Works Published in 2006
Displaying works 81 - 96 of 96 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2006 journal article
A comparison of oral and intravenous pimonidazole in canine tumors using intravenous CCI-103F as a control hypoxia marker
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 64(2), 592–602.
author keywords: hypoxia; pimonidazole; CCI-103F; differential metabolism; pH
MeSH headings : Administration, Oral; Animals; Area Under Curve; Cell Hypoxia; Cell Line; Cricetinae; Cricetulus; Dog Diseases / metabolism; Dogs; Feasibility Studies; Hydrogen-Ion Concentration; Injections, Intravenous; Neoplasms / metabolism; Neoplasms / veterinary; Nitroimidazoles / administration & dosage; Nitroimidazoles / pharmacokinetics
TL;DR:
Oral pimonidazole HCl is effective as a hypoxia marker in spontaneously arising canine tumors and selective cellular uptake and concomitant higher levels of binding in regions of Hypoxia at the high end of pH gradients might account for the greater extent of pimonidsazole binding.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Financial and welfare implications of immediately euthanizing compromised nursery pigs
Journal of Swine Health and Production, 14(1), 25–34.
Source: NC State University Libraries
Added: August 6, 2018
2006 journal article
Sp2 localizes to subnuclear foci associated with the nuclear matrix
MOLECULAR BIOLOGY OF THE CELL, 17(4), 1711–1722.
MeSH headings : Amino Acid Sequence; Animals; COS Cells; Chlorocebus aethiops; Humans; Interphase; Molecular Sequence Data; Nuclear Matrix / chemistry; Nuclear Matrix / metabolism; Protein Array Analysis; Protein Structure, Tertiary; Sequence Deletion; Sp Transcription Factors / analysis; Sp Transcription Factors / metabolism; Sp2 Transcription Factor / analysis; Sp2 Transcription Factor / genetics; Sp2 Transcription Factor / metabolism; Transfection; Zinc Fingers / genetics
TL;DR:
It is concluded that Sp2 preferentially associates with the nuclear matrix and speculate that this subcellular localization plays an important role in the regulation of Sp2 function.
(via Semantic Scholar)
europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 review
Epithelial proteomics in multiple organs and tissues: Similarities and variations between cells, organs, and diseases
[Review of ]. JOURNAL OF PROTEOME RESEARCH, 5(4), 743–755.
author keywords: epithelial cells; proteomics; differentiation; tumorigenesis; cancer; biomarkers
MeSH headings : Biomarkers, Tumor / analysis; Cell Differentiation; Cell Line, Tumor; Epithelial Cells / chemistry; Epithelial Cells / pathology; Epithelial Cells / physiology; Forecasting; Genetic Variation; Genomics; Humans; Models, Biological; Neoplasm Proteins / analysis; Neoplasms / etiology; Neoplasms / genetics; Neoplasms / pathology; Proteome / analysis; Proteomics; Sensitivity and Specificity; Severity of Illness Index
TL;DR:
It is found that most of disease-associated investigation of epithelial proteomics has been focused on epithelial-origin cancer, and there is a significant gap between acute and chronic organ injury, inflammation, and multiple organ dysfunction.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Better understanding of organ dysfunction requires proteomic involvement
JOURNAL OF PROTEOME RESEARCH, 5(5), 1060–1062.
author keywords: organ dysfunction; MODS; proteomics; biomarkers; prognosis
MeSH headings : Biomarkers / analysis; Epithelial Cells / metabolism; Epithelial Cells / pathology; Humans; Multiple Organ Failure / diagnosis; Multiple Organ Failure / metabolism; Multiple Organ Failure / physiopathology; Prognosis; Proteomics / methods; Proteomics / trends
TL;DR:
It is important to have a special attention from proteomic scientists to explore the combination between advanced proteomic biotechnology, clinical proteomics, tissue imaging and profiling, and organ dysfunction score systems, to improve the clinical outcomes of patients with organ dysfunction.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Value of a single-shot turbo spin-echo pulse sequence for assessing the architecture of the subarachnoid space and the constitutive nature of cerebrospinal fluid
VETERINARY RADIOLOGY & ULTRASOUND, 47(3), 254–259.
author keywords: cervical; half-Fourier acquisition single-shot turbo spin echo; magnetic resonance imaging; myelogram; shot turbo spin echo
MeSH headings : Animals; Cat Diseases / cerebrospinal fluid; Cat Diseases / pathology; Cats; Diagnosis, Differential; Dog Diseases / cerebrospinal fluid; Dog Diseases / pathology; Dogs; Encephalitis / complications; Encephalitis / pathology; Encephalitis / veterinary; Female; Lameness, Animal / etiology; Lumbar Vertebrae / pathology; Lymphoma, Non-Hodgkin / complications; Lymphoma, Non-Hodgkin / pathology; Lymphoma, Non-Hodgkin / veterinary; Magnetic Resonance Imaging / methods; Magnetic Resonance Imaging / veterinary; Male; Spinal Cord Neoplasms / complications; Spinal Cord Neoplasms / pathology; Spinal Cord Neoplasms / veterinary; Subarachnoid Space / pathology
TL;DR:
Although the resolution of the single-shot turbo spin-echo pulse sequence images is relatively poor compared with more conventional sequences, the qualitative information about the subarachnoid space and cerebrospinal fluid and the rapid acquisition time, make it a useful sequence to include in standard protocols of spinal magnetic resonance imaging.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Hippocampal neurodegeneration, spontaneous seizures, and mossy fiber sprouting in the F344 rat model of temporal lobe epilepsy
JOURNAL OF NEUROSCIENCE RESEARCH, 83(6), 1088–1105.
author keywords: temporal lobe epilepsy; epilepsy; hippocampal neurodegeneration; spontaneous seizures; mossy fiber sprouting
MeSH headings : Animals; Behavior, Animal; Cell Death / drug effects; Disease Models, Animal; Electroencephalography / methods; Epilepsy, Temporal Lobe / chemically induced; Epilepsy, Temporal Lobe / complications; Epilepsy, Temporal Lobe / pathology; Epilepsy, Temporal Lobe / physiopathology; Fluoresceins; Forelimb / drug effects; Forelimb / physiopathology; Functional Laterality / physiology; Hippocampus / pathology; Immunohistochemistry / methods; In Situ Nick-End Labeling / methods; Kainic Acid / toxicity; Male; Mossy Fibers, Hippocampal / physiopathology; Neuropeptide Y / metabolism; Organic Chemicals; Phosphopyruvate Hydratase / metabolism; Rats; Rats, Inbred F344; Seizures / physiopathology; Silver Staining / methods; Time Factors
TL;DR:
The F344 model appears ideal for testing the efficacy of potential treatment strategies for mesial TLE, and the occurrence of SRMS in this model is always associated with considerable bilateral hippocampal neurodegeneration and aberrant MFS, however, more extensive hippocampal CA3 cell loss and aberant MFS do not appear to increase the frequency ofSRMS.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Identifying the components in eggshell membrane responsible for reducing the heat resistance of bacterial pathogens
JOURNAL OF FOOD PROTECTION, 69(4), 729–738.
MeSH headings : Acetylglucosaminidase / metabolism; Acetylglucosaminidase / pharmacology; Animals; Anti-Bacterial Agents / metabolism; Anti-Bacterial Agents / pharmacology; Bacterial Outer Membrane Proteins / drug effects; Bacterial Outer Membrane Proteins / physiology; Chickens; Conalbumin / metabolism; Conalbumin / pharmacology; Egg Shell / microbiology; Eggs / microbiology; Hot Temperature; Lipase / pharmacology; Membranes / chemistry; Membranes / enzymology; Muramidase / metabolism; Muramidase / pharmacology; Salmonella typhimurium / drug effects; Salmonella typhimurium / growth & development; Time Factors; Trypsin / pharmacology
TL;DR:
Ovotransferrin, lysozyme, and beta-NAGase are the primary components responsible for ESM antibacterial activity and the combination of these proteins interferes with interactions between bacterial lipopolysaccharides, sensitizing the outer bacterial membrane to the lethal affects of heat and possibly pressure and osmotic stressors.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
The pharmacokinetics of orbifloxacin in the horse following oral and intravenous administration
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 29(3), 191–197.
MeSH headings : Administration, Oral; Animals; Anti-Infective Agents / administration & dosage; Anti-Infective Agents / blood; Anti-Infective Agents / pharmacokinetics; Area Under Curve; Ciprofloxacin / administration & dosage; Ciprofloxacin / analogs & derivatives; Ciprofloxacin / blood; Ciprofloxacin / pharmacokinetics; Cross-Over Studies; Drug Administration Schedule; Female; Horses / metabolism; Infusions, Intravenous / veterinary; Male; Protein Binding
TL;DR:
This dose is suggested for further studies on the clinical efficacy of orbifloxacin for treatment of susceptible bacterial infections in the horse, an oral dose of approximately 5 mg/kg once daily will produce plasma concentrations within the suggested range.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2006 article
Cytokine modulation of the innate immune response in feline immunodeficiency virus - Infected cats
Dean, G. A., Lavoy, A., Yearley, J., & Stanton, C. (2006, June 1). JOURNAL OF INFECTIOUS DISEASES, Vol. 193, pp. 1520–1527.
MeSH headings : Animals; Cats; Cytokines / biosynthesis; Cytokines / genetics; Cytokines / immunology; Disease Models, Animal; Female; Immunity, Innate; Immunodeficiency Virus, Feline / immunology; Immunologic Memory; Interferon-gamma / analysis; Lentivirus Infections / immunology; Listeria monocytogenes / genetics; Listeria monocytogenes / immunology; Listeriosis / immunology; Listeriosis / microbiology; Lymph Nodes / immunology; Lymph Nodes / microbiology; Lymphocyte Subsets / immunology; Male; Reverse Transcriptase Polymerase Chain Reaction
TL;DR:
It is hypothesized that altered dendritic-cell function and increased regulatory T cell activity may underlie the innate immune defect in HIV infection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Construction and characterization of feline immunodeficiency virus proviral mutants that coexpress interferon gamma and green fluorescent protein
AIDS RESEARCH AND HUMAN RETROVIRUSES, 22(4), 342–349.
MeSH headings : Animals; Cats; Cell Line; Gene Deletion; Genes, Viral; Green Fluorescent Proteins / metabolism; Immunodeficiency Virus, Feline / genetics; Immunohistochemistry; Interferon-gamma / metabolism; Leukocytes, Mononuclear / cytology; Leukocytes, Mononuclear / virology; Microscopy, Fluorescence; Proviruses / genetics; T-Lymphocytes / cytology; T-Lymphocytes / virology
TL;DR:
Coexpression of IFN-gamma or other cytokines from this attenuated provirus provides the opportunity to evaluate the ability of an immunomodulator to enhance the safety and efficacy of an infectious attenuated DNA vaccine.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Genetic mosaics reveal both cell-autonomous and cell-nonautonomous function of murine p27(Kip1)
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 103(11), 4122–4127.
author keywords: cell cycle; cyclin-dependent kinase inhibitor; growth genetics; pituitary tumor; thymus development
MeSH headings : Animals; Base Sequence; Cyclin-Dependent Kinase Inhibitor p27 / genetics; Cyclin-Dependent Kinase Inhibitor p27 / physiology; DNA / genetics; Female; Hyperplasia; Male; Mice; Mice, Knockout; Mice, Transgenic; Mosaicism; Mutation; Pituitary Gland / metabolism; Pituitary Neoplasms / etiology; Pituitary Neoplasms / genetics; Pituitary Neoplasms / pathology; Radiation Chimera; Spleen / pathology; Thymus Gland / pathology
TL;DR:
The results indicate that the suppression of pars intermedia pituitary tumors by p27(Kip1) is cell-autonomous and does not contribute to overgrowth or infertility phenotypes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 article
Adverse effects of environmental antiandrogens and androgens on reproductive development in mammals
Gray, L. E., Wilson, V. S., Stoker, T., Lambright, C., Furr, J., Noriega, N., … Guillette, L. (2006, February). INTERNATIONAL JOURNAL OF ANDROLOGY, Vol. 29, pp. 96–104.
author keywords: androgens; CAFO feedlot effluent; linuron; p,p'DDT and p,p'DDE; phthalates; polybrominated diphenyl ethers; prochloraz; procymidone; pulp mill effluent; sexual differentiation; vinclozolin
MeSH headings : Androgen Antagonists / pharmacology; Androgen Antagonists / toxicity; Androgen Receptor Antagonists; Androgens / pharmacology; Animals; Environmental Exposure; Female; Male; Pesticides / pharmacology; Pesticides / toxicity; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Receptors, Androgen / metabolism; Sex Differentiation / drug effects; Sex Differentiation / physiology; Xenobiotics / pharmacology; Xenobiotics / toxicity
TL;DR:
Information is presented on the classes of environmental chemicals that display antiandrogenic and androgenic activities in vitro and in vivo and an insight into how exposure to mixtures these chemicals might behave in utero is provided.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Pharmacokinetics and tissue distribution of doxycycline after oral administration of single and multiple doses in horses
AMERICAN JOURNAL OF VETERINARY RESEARCH, 67(2), 310–316.
MeSH headings : Administration, Oral; Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Area Under Curve; Doxycycline / administration & dosage; Doxycycline / blood; Doxycycline / pharmacokinetics; Drug Administration Schedule; Female; Food Deprivation; Half-Life; Horses / metabolism; Male; Tissue Distribution
TL;DR:
Results suggest that doxycycline administered at a dosage of 20 mg/kg, PO, every 24 hours will result in drug concentrations adequate for killing intracellular bacteria and bacteria with minimum inhibitory concentration < or = 0.25 microg/mL.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2006 journal article
(R)-Albuterol elicits antiinflammatory effects in human airway epithelial cells via iNOS
American Journal of Respiratory Cell and Molecular Biology, 34(1), 119–127.
Source: NC State University Libraries
Added: August 6, 2018
2006 review
Host and bacterial factors in listeriosis pathogenesis
[Review of ]. VETERINARY MICROBIOLOGY, 114(1-2), 1–15.
author keywords: listeria; pathogenesis; pregnancy; predisposition; veterinary
MeSH headings : Animals; Cytosol / microbiology; Disease Susceptibility / microbiology; Environment; Female; Food Microbiology; Humans; Immunity, Cellular / immunology; Listeria / growth & development; Listeria / pathogenicity; Listeriosis / immunology; Listeriosis / microbiology; Listeriosis / transmission; Mice; Pregnancy; Pregnancy Complications, Infectious / immunology; Pregnancy Complications, Infectious / microbiology; Vacuoles / microbiology
TL;DR:
There are many features of the pathogenesis of listeriosis that have remained mysterious despite the extensive use of the microorganism in the study of cell-mediated immunity and intracellular growth, and Informational advances such as the sequence of the mouse and listerial genomes, and technical advancessuch as the discovery of listersia-susceptible mouse strains, may renew interest in the project.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
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