Works Published in 2015

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Displaying works 81 - 100 of 134 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2015 journal article

Researching Applicants Online in the Veterinary Program Admissions Process: Perceptions, Practices, and Implications for Curricular Change

JOURNAL OF VETERINARY MEDICAL EDUCATION, 42(4), 286–296.

By: L. Kogan, P. Hellyer, S. Stewart, D. Hendrickson, K. Dowers & R. Schoenfeld-Tacher

author keywords: admissions process; social media; online privacy; professionalism; e-professionalism
MeSH headings : Animals; Attitude of Health Personnel; Canada; Curriculum; Education, Veterinary; Humans; Internet; School Admission Criteria; Schools, Veterinary; Social Networking; Surveys and Questionnaires; United States
TL;DR: The results showed that most veterinary schools do not currently use online research in their admissions process; however, most admissions committee members feel that using online social networking information to investigate applicants is an acceptable use of technology. (via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Pharmacokinetics and distribution of voriconazole in body fluids of dogs after repeated oral dosing

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 38(5), 451–456.

By: J. Lemetayer*, P. Dowling*, S. Taylor* & M. Papich n

MeSH headings : Administration, Oral; Animals; Antifungal Agents / administration & dosage; Antifungal Agents / analysis; Antifungal Agents / blood; Antifungal Agents / cerebrospinal fluid; Antifungal Agents / pharmacokinetics; Aqueous Humor / chemistry; Chromatography, High Pressure Liquid / veterinary; Dogs; Female; Male; Microbial Sensitivity Tests / veterinary; Synovial Fluid / chemistry; Voriconazole / administration & dosage; Voriconazole / analysis; Voriconazole / blood; Voriconazole / cerebrospinal fluid; Voriconazole / pharmacokinetics
TL;DR: Results of this study suggest that twice daily, administration may be necessary to maintain therapeutic plasma concentrations in dogs but further studies are warranted. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2015 journal article

ORAL TRANSMUCOSAL DETOMIDINE GEL FOR THE SEDATION OF THE DOMESTIC FERRET (MUSTELA PUTORILIS FURO)

JOURNAL OF EXOTIC PET MEDICINE, 24(4), 446–454.

By: B. Phillips n, C. Harms n & K. Messenger n

author keywords: ferret; detomidine; transmucosal; sedation; alpha-2-receptor agonist
TL;DR: TM detomidine effectively sedated domestic ferrets for physical examination and venipuncture in a teaching laboratory setting and scored significantly increased throughout the study period. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Genome-wide assessment of recurrent genomic imbalances in canine leukemia identifies evolutionarily conserved regions for subtype differentiation

CHROMOSOME RESEARCH, 23(4), 681–708.

author keywords: Leukemia; Canine; Chromosome; Comparative genomic hybridization; Comparative genomics
MeSH headings : Algorithms; Animals; Cell Transformation, Neoplastic / genetics; Chromosome Aberrations; Chromosome Mapping; Cluster Analysis; Comparative Genomic Hybridization; Conserved Sequence; DNA Copy Number Variations; Disease Models, Animal; Dogs; Evolution, Molecular; Female; Gene Dosage; Genome-Wide Association Study; Genomic Library; Genomics; Humans; In Situ Hybridization, Fluorescence; Leukemia / diagnosis; Leukemia / genetics; Leukemia / metabolism; Male
TL;DR: The use of canine leukemia as a relevant in vivo model for human leukemia is supported and the need to further explore the conserved genomic regions of interest for their clinical impact is justified. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Educational Research Report: Changes in Students' Levels of Empathy during the Didactic Portion of a Veterinary Program

Journal of Veterinary Medical Education, 42(3), 194–205.

By: R. Schoenfeld-Tacher, L. Kogan, B. Meyer-Parsons, K. Royal* & J. Shaw

author keywords: empathy; communication; veterinary students; longitudinal; Davis Interpersonal Reactivity Index
MeSH headings : Adult; Education, Veterinary; Empathy; Female; Humans; Longitudinal Studies; Male; Self Report; Students / psychology; Teaching; Young Adult
UN Sustainable Development Goal Categories
4. Quality Education (OpenAlex)
Sources: Web Of Science, Crossref
Added: August 6, 2018

2015 journal article

Decomposition and carbon storage of selected paper products in laboratory-scale landfills

SCIENCE OF THE TOTAL ENVIRONMENT, 532, 70–79.

author keywords: Landfills; Municipal solid waste; Paper products; Anaerobic decomposition; Biochemical methane potential; Carbon storage
MeSH headings : Biodegradation, Environmental; Carbon / analysis; Carbon Sequestration; Cellulose; Climate Change; Laboratories; Lignin; Methane; Models, Chemical; Paper; Refuse Disposal / methods; Waste Disposal Facilities
TL;DR: The methane yields, carbon storage factors and the extent of cellulose and hemicellulose decomposition all consistently show that papers made from mechanical pulps are less degradable than those made from chemical pulps where essentially all lignin was chemically removed. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Budgett's frog (Lepidobatrachus laevis): A new amphibian embryo for developmental biology

DEVELOPMENTAL BIOLOGY, 405(2), 291–303.

author keywords: Lepidobatrachus; Xenopus; Amphibian; Embryo; Stages; Scaling
MeSH headings : Amphibians; Animals; Anura / embryology; Cell Lineage; Developmental Biology; Embryonic Development; Immunohistochemistry; Models, Animal; Morphogenesis; Organogenesis; Regeneration; Species Specificity; Xenopus laevis / physiology
TL;DR: The Budgett's frog is described, an unusual species with eggs that are over twice the diameter of laboratory Xenopus, and embryos that can tolerate higher temperatures to develop into a tadpole four times more rapidly, which substantially accelerates the pace of experimentation. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

A novel canine kidney cell line model for the evaluation of neoplastic development: karyotype evolution associated with spontaneous immortalization and tumorigenicity

CHROMOSOME RESEARCH, 23(4), 663–680.

By: R. Omeir*, R. Thomas n, B. Teferedegne*, C. Williams n, G. Foseh*, J. Macauley*, L. Brinster*, J. Beren* ...

author keywords: Neoplastic transformation; Tumorigenicity; Canine chromosomes; Comparative genomic hybridization (CGH); Fluorescence in situ hybridization (FISH); Madin-Darby canine kidney (MDCK) cell line; CKB1-3T7 cell line
MeSH headings : Animals; Cell Line; Cell Line, Transformed; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic / genetics; Cells, Cultured; Chromosome Aberrations; DNA Copy Number Variations; Dogs; In Situ Hybridization, Fluorescence; Karyotype; Madin Darby Canine Kidney Cells; Male; Neoplasms / genetics; Neoplasms / pathology
TL;DR: Through integrated cytogenomic and phenotypic characterization of serial passages of CKB1-3T7 from initiation to development of a tumorigenic phenotype, this work presents a robust and readily accessible model of spontaneous neoplastic transformation that overcomes many of the limitations of earlier studies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

A nonclassical MHC class I U lineage locus in zebrafish with a null haplotypic variant

Immunogenetics, 67(9), 501–513.

By: H. Dirscherl n & J. Yoder n

author keywords: Teleost; MHC class I; Evolution; Polymorphism; Haplotype
MeSH headings : Amino Acid Sequence; Animals; Cell Line; Chromosome Mapping; Chromosome Walking; Evolution, Molecular; Female; Gene Expression Profiling; Genotype; Genotyping Techniques; Haplotypes / genetics; Histocompatibility Antigens Class I / classification; Histocompatibility Antigens Class I / genetics; Male; Molecular Sequence Data; Polymorphism, Genetic / genetics; Zebrafish / genetics; Zebrafish / immunology
TL;DR: Two MHC class I U lineage genes are described that map to chromosome 22 in zebrafish and are likely to play a nonclassical role as they lack conservation of key peptide binding residues, display limited polymorphic variation, and exhibit tissue-specific expression. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Naturally Occurring Ehrlichia ewingii and Mycoplasma sp Co-Infection in a Goat

JOURNAL OF VETERINARY INTERNAL MEDICINE, 29(6), 1735–1738.

author keywords: Caprine; Ehrlichiosis; Tick-borne disease
MeSH headings : Animals; Coinfection / microbiology; Coinfection / veterinary; Ehrlichia / isolation & purification; Ehrlichiosis / complications; Ehrlichiosis / microbiology; Ehrlichiosis / veterinary; Female; Goat Diseases / microbiology; Goats; Mycoplasma / isolation & purification; Mycoplasma Infections / complications; Mycoplasma Infections / microbiology; Mycoplasma Infections / veterinary; Polymerase Chain Reaction; RNA, Bacterial / genetics; RNA, Ribosomal, 16S / genetics
TL;DR: A 9-year-old nonpregnant, nonlactating doe Boer goat was examined because of a 2-day history of not being able to stand and some degree of chronicity was considered likely. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Intravenous Cardiac Stem Cell-Derived Exosomes Ameliorate Cardiac Dysfunction in Doxorubicin Induced Dilated Cardiomyopathy

Stem Cells International, 2015, 1–8.

By: A. Vandergriff n, J. de Andrade n, J. Tang n, M. Hensley n, J. Piedrahita n, T. Caranasos*, K. Cheng n

TL;DR: Mice receiving CSC-XOs showed improved heart function via echocardiography, as well as decreased apoptosis and fibrosis, and mice showed no adverse immune reaction, showing promise for overcoming the limitations of stem cells and improving cardiac therapies. (via Semantic Scholar)
Sources: Web Of Science, Crossref
Added: August 6, 2018

2015 journal article

Heparin and LPS-induced COX-2 expression in airway cells: a link between its anti-inflammatory effects and GAG sulfation

EXPERIMENTAL LUNG RESEARCH, 41(9), 499–513.

author keywords: COX-2; heparin; LPS; lung; sulfation
MeSH headings : Anti-Inflammatory Agents, Non-Steroidal / chemistry; Anti-Inflammatory Agents, Non-Steroidal / pharmacology; Cell Line; Cyclooxygenase 2 / genetics; Cyclooxygenase 2 / metabolism; Gene Expression / drug effects; Glycosaminoglycans / chemistry; Glycosaminoglycans / metabolism; Heparin / chemistry; Heparin / pharmacology; Humans; Interleukin-8 / genetics; Interleukin-8 / metabolism; Lipopolysaccharides / toxicity; MAP Kinase Signaling System / drug effects; RNA, Messenger / genetics; RNA, Messenger / metabolism; Respiratory Mucosa / cytology; Respiratory Mucosa / drug effects; Respiratory Mucosa / metabolism
TL;DR: Heparin's anti-inflammatory effects result from its nonspecific suppression of signaling and gene expression and are determined by its sulfation, which may reflect the moderating role of GAG sulfation in lung injury and health. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Evaluation of canine- specific minocycline and doxycycline susceptibility breakpoints for meticillin-resistant Staphylococcus pseudintermedius isolates from dogs

Veterinary Dermatology, 26(5), 334–338.

By: M. Hnot, L. Cole, G. Lorch, M. Papich, P. Rajala-Schultz & J. Daniels

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Effect of feeding on the pharmacokinetics of oral minocycline in healthy research dogs

Veterinary Dermatology, 26(6), 399–405.

By: M. Hnot, L. Cole, G. Lorch, P. Rajala-Schultz & M. Papich

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Association of Gallbladder Mucocele Histologic Diagnosis with Selected Drug Use in Dogs: A Matched Case-Control Study

JOURNAL OF VETERINARY INTERNAL MEDICINE, 29(6), 1464–1472.

By: J. Gookin n, M. Correa n, A. Peters n, A. Malueg n, K. Mathews n, J. Cullen n, G. Seiler n

author keywords: Bile; Canine; Mucus; Xenobiotic
MeSH headings : Animals; Case-Control Studies; Cholinergic Agents / adverse effects; Dog Diseases / chemically induced; Dogs; Female; Gallbladder Diseases / chemically induced; Gallbladder Diseases / veterinary; Hypothyroidism / drug therapy; Imidazoles / adverse effects; Male; Mucocele / chemically induced; Mucocele / pathology; Mucocele / veterinary; Neonicotinoids; Nitro Compounds / adverse effects; Pituitary ACTH Hypersecretion / drug therapy; Pituitary ACTH Hypersecretion / veterinary; Risk Factors; Thyroxine / adverse effects
TL;DR: This study provides evidence for an association between selected drug use and GBM formation in dogs and exposure to imidacloprid in Shetland sheepdogs. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2015 journal article

Posaconazole pharmacokinetics after administration of an intravenous solution, oral suspension, and delayed-release tablet to dogs

AMERICAN JOURNAL OF VETERINARY RESEARCH, 76(5), 454–459.

By: J. Kendall* & M. Papich*

MeSH headings : Administration, Intravenous / veterinary; Administration, Oral; Animals; Antifungal Agents / administration & dosage; Antifungal Agents / pharmacokinetics; Biological Availability; Chromatography, High Pressure Liquid / veterinary; Cross-Over Studies; Delayed-Action Preparations / administration & dosage; Delayed-Action Preparations / pharmacokinetics; Dogs / metabolism; Female; Half-Life; Male; Suspensions / administration & dosage; Suspensions / pharmacokinetics; Tablets / administration & dosage; Tablets / pharmacokinetics; Triazoles / administration & dosage; Triazoles / pharmacokinetics
TL;DR: Absorption of the delayed-release tablets was greater than absorption of the oral suspension, with a longer t1/2 that may favor its clinical use in dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2015 journal article

Plasma Drug Concentrations of Orally Administered Rosuvastatin in Hispaniolan Amazon Parrots (Amazona ventralis)

JOURNAL OF AVIAN MEDICINE AND SURGERY, 29(1), 18–24.

By: H. Beaufrere, M. Papich*, J. Brandao, J. Nevarez & T. Tully

author keywords: atherosclerosis; statins; rosuvastatin; avian; Hispaniolan Amazon parrot; Amazona ventralis
MeSH headings : Administration, Oral; Amazona / blood; Animals; Fluorobenzenes / administration & dosage; Fluorobenzenes / blood; Fluorobenzenes / pharmacokinetics; Hydroxymethylglutaryl-CoA Reductase Inhibitors / administration & dosage; Hydroxymethylglutaryl-CoA Reductase Inhibitors / blood; Hydroxymethylglutaryl-CoA Reductase Inhibitors / pharmacokinetics; Pyrimidines / administration & dosage; Pyrimidines / blood; Pyrimidines / pharmacokinetics; Rosuvastatin Calcium; Sulfonamides / administration & dosage; Sulfonamides / blood; Sulfonamides / pharmacokinetics
TL;DR: Results indicate that rosuvastatin does not appear suitable in Amazon parrots as compounded and used at the dose in this study, and pharmacodynamic studies investigating lipid-lowering effects of statins rather than pharmacokinetic studies may be more practical and cost effective in future studies to screen for a statin with more ideal properties. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2015 journal article

Pharmacokinetic Evaluation of the Equivalency of Gavage, Dietary, and Drinking Water Exposure to Manganese in F344 Rats

TOXICOLOGICAL SCIENCES, 145(2), 244–251.

By: M. Foster n, T. Bartnikas n, L. Johnson n, C. Herrera n, M. Pettiglio n, A. Keene n, M. Taylor n, D. Dorman n

author keywords: manganese; pharmacokinetics; oral exposure; dose rate
MeSH headings : Administration, Oral; Animals; Body Burden; Chlorides / administration & dosage; Chlorides / pharmacokinetics; Chlorides / toxicity; Diet; Food Contamination; Male; Manganese Compounds / administration & dosage; Manganese Compounds / pharmacokinetics; Manganese Poisoning / etiology; Rats, Inbred F344; Risk Assessment; Tissue Distribution; Water Pollutants, Chemical / administration & dosage; Water Pollutants, Chemical / pharmacokinetics; Water Pollutants, Chemical / toxicity
TL;DR: Increased femur, striatum, cerebellum, frontal cortex, and olfactory bulb manganese concentrations were also seen following gavage suggesting that dose rate is an important factor in the pharmacokinetics of oral mangansese. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

PHARMACOKINETICS OF SINGLE-DOSE ORALLY ADMINISTERED CIPROFLOXACIN IN CALIFORNIA SEA LIONS (ZALOPHUS CALIFORNIANUS)

JOURNAL OF ZOO AND WILDLIFE MEDICINE, 46(2), 266–272.

By: L. Barbosa, S. Johnson, M. Papich* & F. Gulland

author keywords: Antibiotic; California sea lion; ciprofloxacin; fluoroquinolone; pharmacokinetic; marine mammal
MeSH headings : Administration, Oral; Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Ciprofloxacin / administration & dosage; Ciprofloxacin / blood; Ciprofloxacin / pharmacokinetics; Dose-Response Relationship, Drug; Sea Lions / blood
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2015 journal article

Initial evaluation of a canine stifle arthrotomy post-operative pain model

VETERINARY JOURNAL, 204(3), 293–298.

By: A. Tomas n, D. Bledsoe, S. Wall n, G. Davidson n & B. Lascelles n

author keywords: Arthrotomy; Ground reaction force; Pain model; Percentage bodyweight distribution; Symmetry index; Extended-release buprenorphine
MeSH headings : Analgesics, Opioid / administration & dosage; Analgesics, Opioid / pharmacology; Animals; Buprenorphine / administration & dosage; Buprenorphine / pharmacology; Cross-Over Studies; Delayed-Action Preparations; Dogs; Male; Orthopedic Procedures / adverse effects; Orthopedic Procedures / veterinary; Pain Measurement / veterinary; Pain, Postoperative / drug therapy; Pain, Postoperative / pathology; Pain, Postoperative / veterinary; Stifle / surgery
TL;DR: Subjective assessments did not detect the pain-inducing effects of arthrotomy or pain-alleviating effects of treatment, and subjective measures of procedural pain in research dogs need to be developed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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