Works Published in 2007

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Displaying works 61 - 79 of 79 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2007 journal article

Mapping phosphoproteins in Mycoplasma genitalium and Mycoplasma pneumoniae

BMC Microbiology, 7.

By: H. Su, C. Hutchison & M. Giddings

Source: NC State University Libraries
Added: August 6, 2018

2007 journal article

Effects of serial passaging on the adipogenic and osteogenic differentiation potential of adipose-derived human mesenchymal stem cells

TISSUE ENGINEERING, 13(6), 1291–1298.

MeSH headings : Adipocytes / cytology; Adipocytes / physiology; Adipogenesis / physiology; Adult; Cell Culture Techniques / methods; Cell Differentiation; Cells, Cultured; Female; Humans; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / physiology; Middle Aged; Osteocytes / cytology; Osteocytes / physiology; Osteogenesis / physiology; Tissue Engineering / methods
TL;DR: The results of this study indicate that adipose-derived hMSCs are capable of both adipogenic and osteogenic differentiation through 10 passages (34 population doublings) but that osteogenic differentiate may start to dominate at later passages. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Differential effects on messenger ribonucleic acid expression by bone marrow-derived human mesenchymal stem cells seeded in agarose constructs due to ramped and steady applications of cyclic hydrostatic pressure

TISSUE ENGINEERING, 13(6), 1151–1158.

By: A. Finger n, C. Sargent n, K. Dulaney n, S. Bernacki n & E. Loboa n

MeSH headings : Adolescent; Adult; Biocompatible Materials / chemistry; Bone Marrow Cells / cytology; Bone Marrow Cells / drug effects; Bone Marrow Cells / metabolism; Cell Culture Techniques / methods; Cells, Cultured; Chondrocytes / cytology; Chondrocytes / drug effects; Chondrocytes / metabolism; Chondrogenesis / drug effects; Chondrogenesis / physiology; Cytoskeletal Proteins / genetics; Cytoskeletal Proteins / metabolism; Gene Expression Regulation, Developmental / drug effects; Gene Expression Regulation, Developmental / physiology; Humans; Male; Mechanotransduction, Cellular / drug effects; Mechanotransduction, Cellular / physiology; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / drug effects; Mesenchymal Stem Cells / metabolism; Pressure; RNA, Messenger / metabolism; Sepharose / chemistry; Tissue Engineering / methods; Transforming Growth Factor beta / administration & dosage
TL;DR: Findings indicate that hydrostatic pressure may induce chondrogenesis in hMSC-seeded agarose constructs without TGF-beta, and that hMSCs are capable of withstanding high initial pressures that may initiate chondrogensesis faster than lower pressures. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Human adipose-derived adult stem cells upregulate palladin during osteogenesis and in response to cyclic tensile strain

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 293(5), C1532–C1538.

By: M. Wall n, A. Rachlin, C. Otey* & E. Loboa*

author keywords: adipose-derived adult stem cells; mechanobiology; Eps8; actin cytoskeleton; mesenchymal stem cells
MeSH headings : Actins / metabolism; Adaptor Proteins, Signal Transducing; Adipose Tissue / cytology; Adipose Tissue / metabolism; Adult; Adult Stem Cells / metabolism; Cell Lineage / genetics; Cell Shape; Cells, Cultured; Cytoskeletal Proteins / genetics; Cytoskeletal Proteins / metabolism; Female; Humans; Intracellular Signaling Peptides and Proteins / metabolism; Mechanotransduction, Cellular / genetics; Middle Aged; Osteogenesis / genetics; Phosphoproteins / genetics; Phosphoproteins / metabolism; Protein Isoforms / metabolism; RNA Interference; RNA, Messenger / metabolism; RNA, Small Interfering / metabolism; Stress Fibers / metabolism; Stress, Mechanical; Up-Regulation
TL;DR: It is shown that palladin was expressed by hADAS cells and was modulated during osteogenic differentiation and in response to cyclic tensile strain, and that knocking down the palladin gene resulted in decreased actin stress fibers and decreased protein levels of Eps8. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Genetic background influences fluoride's effects on osteoclastogenesis

BONE, 41(6), 1036–1044.

By: D. Yan*, A. Gurumurth*, M. Wright n, T. Pfeiler n, E. Loboa n & E. Everett*

author keywords: F; osteoclastogenesis; hematopoietic colony-forming cell (CFC) assays; bone resorption markers; inbred mouse strains
MeSH headings : Alkaline Phosphatase / metabolism; Animals; Biomarkers / blood; Bone Density; Bone and Bones / cytology; Bone and Bones / metabolism; Colony-Forming Units Assay; Female; Fluorides / metabolism; Fluorides / pharmacology; Mice; Osteoclasts / drug effects; Osteoclasts / metabolism; Osteogenesis / drug effects; Osteogenesis / genetics; Stress, Mechanical
TL;DR: In conclusion, short term F treatment at physiological levels has strain-specific effects in mice and novel actions hallmarked by enhanced osteoclastogenesis shifts in hematopoietic cell differentiation in the C3H strain are demonstrated. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Distributing a fixed amount of cyclic loading to tendon explants over longer periods induces greater cellular and mechanical responses

JOURNAL OF ORTHOPAEDIC RESEARCH, 25(8), 1078–1086.

By: A. Devkota n, M. Tsuzaki*, L. Almekinders, A. Banes n & P. Weinhold n

author keywords: tendon overuse injury; tendinopathy; tendon explant
MeSH headings : Animals; Biomechanical Phenomena; Cell Death; Chickens; Collagenases / metabolism; Cumulative Trauma Disorders / physiopathology; Dinoprostone / metabolism; Female; Glycosaminoglycans / metabolism; Organ Culture Techniques; Stress, Mechanical; Tendon Injuries / physiopathology; Tendons / cytology; Tendons / physiopathology; Time Factors; Weight-Bearing
TL;DR: Mechanical fatigue‐induced mechanical property changes were exhibited by the tendons in response to increased loading magnitude across just 1 day, however, when the same loading was applied over a longer period, most outcomes were magnified substantially, relative to the short duration regimens. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Semiautomated finite element mesh generation methods for a long bone

COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE, 85(3), 196–202.

author keywords: canine radius; CT to FEA; four-point bending; strain gage
MeSH headings : Animals; Bone and Bones / diagnostic imaging; Cadaver; Computer Simulation; Dogs; Finite Element Analysis; North Carolina; Tomography, X-Ray Computed
TL;DR: A semi-automated finite element mesh generation method using computed tomography image data of a canine radius is developed and test to minimize user interaction and eliminate the need for mesh smoothing to produce a model suitable for finite element analysis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Nanostructured GaN nucleation layer for light-emitting diodes

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 7(8), 2719–2725.

By: J. Narayan*, P. Pant*, W. Wei*, R. Narayan* & J. Budai

author keywords: gallium nitride; nanostructured nucleation layer; light emitting diodes (LEDs); domain matching epitaxy
MeSH headings : Aluminum Oxide; Crystallization; Gallium / chemistry; Hot Temperature; Light; Microscopy, Atomic Force; Microscopy, Electron, Transmission; Molecular Conformation; Nanoparticles / chemistry; Nanotechnology / instrumentation; Nanotechnology / methods; Photochemistry / methods; Semiconductors; X-Rays
TL;DR: The NL layer grows epitaxially with the (0001) sapphire substrate by domain matching epitaxy, and this epitaxial relationship is remarkably maintained when c-GaN converts into h- GaN during high-temperature growth. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Grafting of poly(N-isopropylacrylamide) onto nylon and polystyrene surfaces by atmospheric plasma treatment followed with free radical graft copolymerization

JOURNAL OF APPLIED POLYMER SCIENCE, 104(6), 3614–3621.

By: X. Wang n & M. McCord n

author keywords: polystyrene; hydrogels; biomaterials; graft copolymers; plasma polymerization
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Development, optimization, and characterization of electrospun poly(lactic acid) nanofibers containing multi-walled carbon nanotubes

JOURNAL OF APPLIED POLYMER SCIENCE, 105(3), 1668–1678.

author keywords: electrospinning; polymers; nanofibers; carbon nanotubes; electrical properties; mechanical properties; electron microscopy
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Selection and initial characterization of novel peptide ligands that bind specifically to human blood outgrowth endothelial cells

BIOTECHNOLOGY AND BIOENGINEERING, 98(1), 306–312.

By: A. Veleva n, S. Cooper* & C. Patterson*

author keywords: human blood outgrowth endothelial cells (HBOEC); phage displayed peptide library screening; cell-specific; peptides; progenitor cell-based therapies
MeSH headings : Endothelial Cells / metabolism; Humans; Ligands; Peptide Library; Peptides / metabolism; Protein Binding; Protein Interaction Mapping / methods
TL;DR: The isolated 12-mer peptide ligands that bind to human blood outgrowth endothelial cells (HBOEC) display outstanding cell specificity and are expected to be exploited in the development of future cell-based therapeutic revascularization approaches to ischemic disease and endothelial injury. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Probing protein adsorption onto mercaptoundecanoic acid stabilized gold nanoparticles and surfaces by quartz crystal microbalance and zeta-potential measurements

LANGMUIR, 23(11), 6053–6062.

By: E. Kaufman n, J. Belyea n, M. Johnson n, Z. Nicholson n, J. Ricks n, P. Shah n, M. Bayless n, T. Pettersson n ...

MeSH headings : Adsorption; Animals; Biosensing Techniques; Cattle; Coated Materials, Biocompatible / chemistry; Cytochromes c / chemistry; Electrochemistry; Fatty Acids / chemistry; Gold / chemistry; Hydrogen-Ion Concentration; In Vitro Techniques; Metal Nanoparticles / chemistry; Myoglobin / chemistry; Proteins / chemistry; Quartz; Serum Albumin, Bovine / chemistry; Surface Properties
TL;DR: The observation of stable BSA complexes on MUA/AuNPs at the isoelectric point by zeta-potential measurements demonstrates that BSA can sterically stabilize MUA /AuNP. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Fragmentation characteristics of collision-induced dissociation in MALDI TOF/TOF mass spectrometry

ANALYTICAL CHEMISTRY, 79(8), 3032–3040.

By: J. Khatun n, K. Ramkissoon n & M. Giddings n

MeSH headings : Amino Acids / chemistry; Data Interpretation, Statistical; Proteins / chemistry; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
TL;DR: Fragmentation in MALDI TOF/TOF mass spectrometry is analyzed, collecting statistics using a curated set of 2459 MS/MS spectra and applying bootstrap resampling to assess confidence intervals. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2007 article

Next generation biomaterials - Preface

Narayan, R. J., Bhaduri, S. B., Fischman, G., Rigsbee, J. M., & Zhang, X. (2007, April). MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS, Vol. 27, pp. 345–346.

By: R. Narayan*, S. Bhaduri, G. Fischman, J. Rigsbee* & X. Zhang*

UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Effects of mechanical flexion on the penetration of fullerene amino acid-derivatized peptide nanoparticles through skin

NANO LETTERS, 7(1), 155–160.

MeSH headings : Amino Acids / chemistry; Fluorescein-5-isothiocyanate; Fullerenes / chemistry; Microscopy, Confocal; Nanoparticles / chemistry; Nuclear Localization Signals; Peptides / pharmacokinetics; Skin Absorption
TL;DR: TEM analysis revealed fullerene-peptide localization within the intercellular spaces of the stratum granulosum in skin flexed for 60 and 90 min, whereas Baa-Lys(FITC)-NLS did not penetrate into the dermis of unflexed skin until 24 h. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2007 journal article

ATP reduces gel compaction in osteoblast-populated collagen gels

JOURNAL OF APPLIED PHYSIOLOGY, 102(3), 1152–1160.

By: J. Qi*, L. Chi*, J. Faber*, B. Koller & A. Banes*

author keywords: adenosine triphosphate; three-dimensional culture; purinoceptor; osteoblast; extracellular matrix
MeSH headings : Adenosine Triphosphate / metabolism; Adenosine Triphosphate / physiology; Animals; Biomechanical Phenomena; Bone Remodeling / physiology; Cell Adhesion; Cell Culture Techniques; Cell Line; Cell Survival; Collagen Type I; Extracellular Fluid; Gene Expression Profiling; Hydrolysis; Kinetics; Mice; Nucleotides / physiology; Osteoblasts / physiology; Receptors, Purinergic P2 / physiology; Stress, Mechanical
TL;DR: A potential role for P2 receptors in matrix remodeling and repair and as a potential drug target in treatment of bone diseases is suggested. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

A linear dilution microfluidic device for cytotoxicity assays

LAB ON A CHIP, 7(2), 226–232.

By: G. Walker n, N. Monteiro-Riviere n, J. Rouse n & . Adrian T. O'Neill n

MeSH headings : Cells, Cultured; Combinatorial Chemistry Techniques; Diffusion; Drug Evaluation, Preclinical / instrumentation; Drug Evaluation, Preclinical / methods; Electrochemistry / methods; Equipment Design; Humans; Keratinocytes / cytology; Keratinocytes / drug effects; Microchemistry; Microfluidic Analytical Techniques / instrumentation; Microfluidic Analytical Techniques / methods; Microfluidics; Models, Statistical; Models, Theoretical
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Connexin 43 is localized with actin in tenocytes

CELL MOTILITY AND THE CYTOSKELETON, 64(2), 121–130.

By: M. Wall*, C. Otey*, J. Qi* & A. Banes*

author keywords: cyclic strain; cytoskeleton; gap junctions; tendon; myosin II
MeSH headings : Actin Cytoskeleton / metabolism; Actins / analysis; Actins / metabolism; Adult; Animals; Birds; COS Cells; Cells, Cultured; Child, Preschool; Chlorocebus aethiops; Connexin 43 / analysis; Connexin 43 / metabolism; Female; Fibroblasts / chemistry; Gap Junctions / chemistry; Gap Junctions / metabolism; Humans; Male; Middle Aged; Myosin Type II / metabolism; Stress, Mechanical; Tendons / chemistry; Tendons / cytology
TL;DR: Connexin 43 (Cx43) may associate with actin to stabilize gap junctions at the plasma membrane, ensuring that tenocytes remain coupled during periods of prolonged or intense mechanical loading. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Two photon polymerization of polymer-ceramic hybrid materials for transdermal drug delivery

INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY, 4(1), 22–29.

TL;DR: 2PP is able to create microneedle structures for transdermal drug delivery with a larger range of geometries than conventional microfabrication techniques, and human epidermal keratinocyte viability on the Ormocer® surfaces polymerized using 2PP was similar to that on control surfaces. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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