Works Published in 2003

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Displaying works 21 - 40 of 84 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2003 article

Differential effects of albuterol isomers on normal human bronchial epithelial cells in vitro.

American Journal of Respiratory and Critical Care Medicine, Vol. 167, p. A205.

Source: NC State University Libraries
Added: August 6, 2018

2003 article

Activation of protease-activated receptors?2 (PAR-2) is not associated with enhanced mucin secretion by well-differentiated normal human bronchial epithelial cells in vitro.

American Journal of Respiratory and Critical Care Medicine, Vol. 167, p. A204.

Source: NC State University Libraries
Added: August 6, 2018

2003 article

A myristoylated peptide directed against the N-terminal region of MARCKS protein inhibits mucin secretion in ovalbumin sensitized/challenged mice in vivo.

American Journal of Respiratory and Critical Care Medicine, Vol. 167, p. A17.

By: B. Vargaftig, M. Singer, L. Martin, Y. Li & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

UP1 extends life of primary porcine fetal fibroblasts in culture

CLONING AND STEM CELLS, 5(2), 143–148.

By: B. Mir n, N. Tanner*, B. Chowdhary* & J. Piedrahita n

MeSH headings : Animals; Antioxidants / pharmacology; Cell Survival / drug effects; Cells, Cultured; Chromosome Aberrations; Culture; Electroporation; Fetus / cytology; Fibroblasts / cytology; Fibroblasts / drug effects; Glutathione / pharmacology; Heterogeneous-Nuclear Ribonucleoprotein Group A-B / genetics; Heterogeneous-Nuclear Ribonucleoprotein Group A-B / metabolism; Hydroxylamines / pharmacology; Karyotyping; Swine / embryology
TL;DR: Effect of two anti-oxidants, glutathione and n-t-butyl hydroxylamine, and of the expression of UP1, a shortened derivative of heterogeneous nuclear riboprotein (hnRNP)A1, on the life extension of primary porcine fibroblasts in culture is reported. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Pleural fluid from a dog with marked eosinophilia

VETERINARY CLINICAL PATHOLOGY, 32(3), 147–149.

By: E. Cowgill n & J. Neel n

author keywords: dog; eosinophilic inflammation; mast cell tumor; mastocytosis; skin; systemic mastocytosis; visceral mast cell neoplasia
MeSH headings : Animals; Biopsy, Fine-Needle / veterinary; Bone Marrow / pathology; Diagnosis, Differential; Dog Diseases / diagnosis; Dog Diseases / diagnostic imaging; Dog Diseases / pathology; Dogs; Fatal Outcome; Male; Mast-Cell Sarcoma / diagnosis; Mast-Cell Sarcoma / pathology; Mast-Cell Sarcoma / veterinary; Mediastinal Neoplasms / diagnosis; Mediastinal Neoplasms / pathology; Mediastinal Neoplasms / veterinary; Pleural Effusion, Malignant / cytology; Pleural Effusion, Malignant / diagnostic imaging; Pleural Effusion, Malignant / pathology; Pleural Effusion, Malignant / veterinary; Pulmonary Eosinophilia / diagnosis; Pulmonary Eosinophilia / pathology; Pulmonary Eosinophilia / veterinary; Radiography, Thoracic / veterinary
TL;DR: The dog was diagnosed with systemic (visceral) mastocytosis, a rare form of neoplasia in dogs, and was euthanized. (via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Identification of a mechanism by which lens epithelial cells limit accumulation of overexpressed ferritin H-chain

JOURNAL OF BIOLOGICAL CHEMISTRY, 278(44), 42920–42926.

By: M. Goralska n, B. Holley n & M. McGahan n

MeSH headings : Animals; Apoferritins; Blotting, Western; Cataract / metabolism; Cytosol / metabolism; DNA, Complementary / metabolism; Dogs; Electrophoresis, Polyacrylamide Gel; Epithelial Cells / metabolism; Eye Diseases, Hereditary / metabolism; Ferritins / biosynthesis; Ferritins / chemistry; Ferritins / metabolism; Humans; Iron Metabolism Disorders; Lens, Crystalline / metabolism; Mutation; Peptides / chemistry; Plasmids / metabolism; Precipitin Tests; RNA, Messenger / metabolism; Recombinant Proteins / metabolism; Time Factors; Transfection
TL;DR: It is concluded that lens epithelial cells differentially regulate concentration of both ferritin chains in the cytosol, which indicates that the inability of cells to more strictly control cytosolic levels of L-chain may augment its accumulation in lenses of humans with hereditary hyperferritinemia cataract syndrome. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Antimicrobial therapy for gastrointestinal diseases

Veterinary Clinics of North America: Equine Practice, 19(3), 645–663.

By: M. Papich n

MeSH headings : Animals; Anti-Bacterial Agents / adverse effects; Anti-Bacterial Agents / therapeutic use; Bacterial Infections / chemically induced; Bacterial Infections / microbiology; Bacterial Infections / veterinary; Colic / chemically induced; Colic / microbiology; Colic / veterinary; Diarrhea / chemically induced; Diarrhea / microbiology; Diarrhea / veterinary; Drug Resistance, Bacterial; Gastrointestinal Diseases / chemically induced; Gastrointestinal Diseases / microbiology; Gastrointestinal Diseases / veterinary; Horse Diseases / chemically induced; Horse Diseases / microbiology; Horses; Intestinal Absorption; Intestines / microbiology; Kinetics
TL;DR: There is justification for antibiotic therapy for the conditions described in this article and disruption of the endogenous bacterial population, colitis, and diarrhea are the most common complications from antibiotic therapy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2003 journal article

Pharmacokinetics of florfenicol in loggerhead sea turtles (Caretta caretta) after single intravenous and intramuscular injections

Journal of Zoo and Wildlife Medicine, 34(1), 3–8.

By: M. Stamper n, M. Papich*, G. Lewbart*, S. May, D. Plummer* & M. Stoskopf*

TL;DR: Florfenicol does not appear to be a practical antibiotic in sea turtles when administered at these doses, and plasma florfenicol plasma concentrations were below the minimum inhibitory concentrations for sensitive bacteria within 1 hr. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2003 journal article

Mutational analysis of LoxP sites for efficient Cre-mediated insertion into genomic DNA

GENESIS, 36(3), 162–167.

By: J. Thomson*, E. Rucker* & J. Piedrahita n

author keywords: Cre recombinase; mutant loxP; insertion; lambda integrase
MeSH headings : Base Sequence; DNA Mutational Analysis; DNA Primers; Electroporation; Integrases / genetics; Molecular Sequence Data; Mutagenesis, Insertional / methods; Mutation / genetics; Plasmids / genetics; Viral Proteins / genetics
TL;DR: The Cre/loxP system has been used in transgenic models primarily to excise DNA flanked by loxP sites for gene deletion, but the insertion reaction is more difficult to control since the excision event is kinetically favored. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Influence of pregnancy on the pathogenesis of listeriosis in mice inoculated intragastrically

INFECTION AND IMMUNITY, 71(9), 5202–5209.

By: T. Hamrick n, . Horton n, P. Spears n, E. Havell n, I. Smoak n & P. Orndorff n

MeSH headings : Animals; Base Sequence; Colon / microbiology; Colony Count, Microbial; DNA, Bacterial / genetics; Enterocytes / microbiology; Female; Listeria monocytogenes / genetics; Listeria monocytogenes / isolation & purification; Listeria monocytogenes / pathogenicity; Listeriosis / complications; Listeriosis / etiology; Liver / microbiology; Mice; Mutagenesis, Insertional; Pregnancy; Pregnancy Complications, Infectious / etiology; Risk Factors; Spleen / microbiology; Virulence / genetics
TL;DR: The ability of the 4nonb strain to produce a lethal infection in pregnant animals did not correlate with an increased incidence or level of liver and spleen colonization over that in nonpregnant females, but the lethality rate did correlate well with the rate at which embryos and their surrounding decidual covering became infected, suggesting that intrauterine infection could be responsible for the increased disease severity in the gravid females. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Comparison of the cardiorespiratory effects of medetomidine- butorphanol-ketamine and medetomidine-butorphanol-midazolam in patas monkeys (Erythrocebus patas)

Journal of Zoo and Wildlife Medicine, 34(1), 47–52.

Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

Disposition and analgesic cockatoos effects of fentanyl in white (Cacatua alba)

JOURNAL OF AVIAN MEDICINE AND SURGERY, 17(3), 124–130.

By: S. Hoppes n, K. Flammer n, K. Hoersch*, M. Papich n & J. Paul-Murphy*

author keywords: fentanyl; opioids; analgesia; pharmacokinetics; psittaciformes; cockatoo; Cacatua alba
TL;DR: Although the 0.2 mg/kg SC dose provided significant analgesia in some birds, fentanyl at this dose is not recommended as a routine analgesic agent because a large volume of drug must be injected and this dose causes hyperactivity in some Birds. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2003 journal article

Comparison of peripheral-to-central circulation delivery times between intravenous and intraosseous infusion in foals

Equine Veterinary Education, 15(4), 201–206.

By: L. Tate n, C. Berry* & C. King*

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

Atypical development of the tracheal basement membrane zone of infant rhesus monkeys exposed to ozone and allergen

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 285(4), L931–L939.

By: M. Evans, M. Fanucchi, G. Baker, L. Van Winkle*, L. Pantle, S. Nishio, E. Schelegle*, L. Gershwin* ...

author keywords: perlecan; fibroblast growth factor-2; fibroblast growth factor; receptor-1; syndecan-4; epithelial-mesenchymal trophic unit
MeSH headings : Allergens / pharmacology; Animals; Animals, Newborn / growth & development; Basement Membrane / anatomy & histology; Basement Membrane / drug effects; Basement Membrane / growth & development; Basement Membrane / metabolism; Collagen Type I / metabolism; Drug Combinations; Fibroblast Growth Factor 2 / metabolism; Heparan Sulfate Proteoglycans / metabolism; Immunohistochemistry; In Vitro Techniques; Macaca mulatta; Membrane Glycoproteins / metabolism; Ozone / pharmacology; Proteoglycans / metabolism; Pyroglyphidae / immunology; Receptor Protein-Tyrosine Kinases / metabolism; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor / metabolism; Syndecan-4; Trachea / anatomy & histology; Trachea / drug effects; Trachea / growth & development; Trachea / metabolism
TL;DR: It is concluded that ozone and HDMA plus ozone effected incorporation of perlecan into the BMZ, resulting in atypical development of theBMZ, which may be associated with the developmental problems of lungs associated with exposure to ozone. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2003 journal article

A retrospective analysis of 140 dogs with oral melanoma treated with external beam radiation

VETERINARY RADIOLOGY & ULTRASOUND, 44(3), 352–359.

By: D. Proulx n, D. Ruslander n, R. Dodge*, M. Hauck n, L. Williams n, B. Horn, G. Price, D. Thrall n

author keywords: dog; oral malignant melanoma; radiation therapy; prognostic factors
MeSH headings : Animals; Disease-Free Survival; Dog Diseases / mortality; Dog Diseases / radiotherapy; Dogs; Dose Fractionation, Radiation; Female; Male; Melanoma / mortality; Melanoma / veterinary; Mouth Neoplasms / mortality; Mouth Neoplasms / veterinary; Neoplasm Recurrence, Local / mortality; Neoplasm Recurrence, Local / veterinary; North Carolina / epidemiology; Records / veterinary; Retrospective Studies; Survival Analysis; Treatment Outcome
TL;DR: External beam radiation therapy is effective in local disease control of canine oral malignant melanoma; however, the optimal fractionation scheme has yet to be determined and further investigation into novel therapies is warranted. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2003 journal article

The effect of UVB irradiation on ferritin subunit synthesis, ferritin assembly and Fe metabolism in cultured canine lens epithelial cells

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 77(4), 440–445.

By: J. Harned*, A. Grimes* & M. McGahan

TL;DR: It was hypothesized and then determined that newly synthesized chains did not assemble into functional holoferritin, and this study provides a cautionary note regarding the conclusions of such studies in the absence of data indicating assembly of functional ferritin molecules. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Steroidogenic responses of pig corpora lutea to insulin-like growth factor I (IGF-I) throughout the oestrous cycle

REPRODUCTION, 125(2), 241–249.

TL;DR: IGF-I has steroidogenic actions only on 'young' (days 4-7) pig corpora lutea; endogenous IGF-I and IGFBP are insufficient to modulate progesterone secretion in vitro; and the steroidsogenic actions of IGF- I are mediated via PI-3-kinase. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2003 journal article

Pharmacologic management in veterinary behavioral medicine

Veterinary Clinics of North America: Small Animal Practice, 33(2), 365–404.

By: B. Simpson n & M. Papich n

MeSH headings : Animals; Anxiety Disorders / drug therapy; Behavior, Animal; Cat Diseases / drug therapy; Cats / metabolism; Dog Diseases / drug therapy; Dogs / metabolism; Psychotropic Drugs / pharmacokinetics; Psychotropic Drugs / therapeutic use; Veterinary Drugs
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2003 journal article

Is there a physiological role for the neurosteroid THDOC in stress-sensitive conditions?

TRENDS IN PHARMACOLOGICAL SCIENCES, 24(3), 103–106.

By: D. Reddy n

MeSH headings : Animals; Anti-Anxiety Agents / pharmacology; Brain / metabolism; Desoxycorticosterone / analogs & derivatives; Desoxycorticosterone / pharmacology; Desoxycorticosterone / physiology; GABA-A Receptor Antagonists; Humans; Stress, Physiological / metabolism
TL;DR: Recent studies indicate that stress induces THDOC to levels that can activate GABA(A) receptors, which might have significant implications for human stress-sensitive conditions such as epilepsy, post-traumatic stress disorder and depression. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Effects of hydrochloric, acetic, butyric, and propionic acids on pathogenesis of ulcers in the nonglandular portion of the stomach of horses

AMERICAN JOURNAL OF VETERINARY RESEARCH, 64(4), 404–412.

By: J. Nadeau n, F. Andrews n, C. Patton n, R. Argenzio n, A. Mathew n & A. Saxton n

MeSH headings : Acetic Acid / adverse effects; Animals; Butyric Acid / adverse effects; Culture Techniques; Fatty Acids, Volatile / adverse effects; Female; Gastric Mucosa / drug effects; Gastric Mucosa / pathology; Horse Diseases / chemically induced; Horse Diseases / etiology; Horse Diseases / pathology; Horses; Hydrochloric Acid / adverse effects; Hydrogen-Ion Concentration; Male; Membrane Potentials / drug effects; Propionates / adverse effects; Stomach / drug effects; Stomach / pathology; Stomach Ulcer / chemically induced; Stomach Ulcer / etiology; Stomach Ulcer / pathology; Stomach Ulcer / veterinary; Time Factors
TL;DR: Results indicate that HCl alone or in combination with VFAs at gastric pH < or = 4.0 may be important in the pathogenesis of gastric ulcers in the nonglandular portion of the stomach of horses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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