Works Published in 2013
Displaying works 61 - 80 of 127 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2013 journal article
Expression of Genes Associated with Apoptosis in the Porcine Corpus Luteum During the Oestrous Cycle
REPRODUCTION IN DOMESTIC ANIMALS, 48(5), 755–761.
MeSH headings : Animals; Apoptosis / physiology; Corpus Luteum / metabolism; Estrous Cycle / physiology; Female; Gene Expression Regulation / physiology; Pregnancy; RNA, Messenger / genetics; RNA, Messenger / metabolism; Swine / physiology
TL;DR:
It is concluded that apoptosis-associated proteins (i.e. Bcl-x and Caspase 3) may play a critical role in luteolytic sensitivity in the pig.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2013 journal article
Effects of tepoxalin and medetomidine on glomerular filtration rate in dogs
Journal of Veterinary Medical Science, 75(1), 69–74.
Source: NC State University Libraries
Added: August 6, 2018
2013 journal article
CONSTRAINTS ON MAMMALIAN FORELIMB DEVELOPMENT: INSIGHTS FROM DEVELOPMENTAL DISPARITY
Evolution, 67(12), 3645–3652.
author keywords: Constraints; diversity; limb; mammal; morphometrics; ontogeny
MeSH headings : Animals; Evolution, Molecular; Forelimb / anatomy & histology; Forelimb / embryology; Horses / embryology; Horses / genetics; Mice / embryology; Mice / genetics; Opossums / embryology; Opossums / genetics; Swine / embryology; Swine / genetics
TL;DR:
Investigation of levels and patterns of morphological diversity (disparity) among the developing forelimbs of four mammals with diverse limb morphologies indicates that disparity slightly decreases or stays the same from the appearance of the limb ridge to the bud stage, and increases dramatically from the paddle through tissue regression stages.
(via Semantic Scholar)
onlinelibrary.wiley.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref
Added: August 6, 2018
2013 journal article
Alternating Current Electric Fields of Varying Frequencies: Effects on Proliferation and Differentiation of Porcine Neural Progenitor Cells
Cellular Reprogramming, 15(5), 405–412.
MeSH headings : Animals; Cell Differentiation; Cell Proliferation; Cells, Cultured; Electricity; Electrodes; Fluorescence; Glial Fibrillary Acidic Protein / metabolism; Neural Stem Cells / cytology; Swine; Swine, Miniature; Tubulin / metabolism
TL;DR:
Higher frequency stimulation of low-frequency alternating current EFs via IDEs did not alter the alignment and proliferation of porcine neural progenitor cells, but higher frequency stimulation appeared to delay differentiation into mature astrocytes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref
Added: August 6, 2018
2013 journal article
Stability of three commonly compounded extemporaneous enrofloxacin suspensions for oral administration to exotic animals
JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 243(1), 85–90.
MeSH headings : Administration, Oral; Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / chemistry; Drug Compounding; Drug Stability; Enrofloxacin; Fluoroquinolones / administration & dosage; Fluoroquinolones / chemistry; Pets; Suspensions / chemistry
TL;DR:
Results indicated that, when stored in amber-colored vials at room temperature for 56 days, the enrofloxacin concentration strength in all 3 formulations was retained within acceptance criteria of 90% to 110%.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2013 journal article
Ronidazole pharmacokinetics in cats following delivery of a delayed-release guar gum formulation
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 36(4), 399–407.
MeSH headings : Animals; Antiprotozoal Agents / administration & dosage; Antiprotozoal Agents / blood; Antiprotozoal Agents / pharmacokinetics; Area Under Curve; Cats / blood; Cats / metabolism; Delayed-Action Preparations; Galactans / chemistry; Half-Life; Male; Mannans / chemistry; Plant Gums / chemistry; Ronidazole / administration & dosage; Ronidazole / blood; Ronidazole / pharmacokinetics; Tablets
TL;DR:
Delayed release of ronidazole from guar gum-coated tablets indicates that release of RDZ may be delayed to deliver the medication to a targeted area of the intestine in cats.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2013 journal article
Polyomavirus-Associated Nephritis in 2 Horses
VETERINARY PATHOLOGY, 50(5), 769–774.
author keywords: kidney; horse; myocarditis; nephritis; polyomavirus
MeSH headings : Animals; Blood Chemical Analysis / veterinary; Capsid Proteins / genetics; DNA Primers / genetics; Fatal Outcome; Female; Horse Diseases / immunology; Horse Diseases / pathology; Horse Diseases / virology; Horses; Immunocompromised Host / immunology; Immunoglobulin G / blood; Immunohistochemistry / veterinary; Kidney Cortex Necrosis / pathology; Kidney Cortex Necrosis / veterinary; Kidney Cortex Necrosis / virology; Male; Nephritis, Interstitial / pathology; Nephritis, Interstitial / veterinary; Nephritis, Interstitial / virology; Phylogeny; Polyomavirus / genetics; Polyomavirus Infections / pathology; Polyomavirus Infections / veterinary
TL;DR:
2 Standardbred horses with tubular necrosis and tubulointerstitial nephritis associated with productive equine polyomvirus infection that resembles BK polyomavirus nephropathy in immunocompromised humans are described.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Measurement of carbon storage in landfills from the biogenic carbon content of excavated waste samples
WASTE MANAGEMENT, 33(10), 2001–2005.
author keywords: Landfill; Carbon storage; Municipal solid waste
MeSH headings : Biodegradation, Environmental; Carbon / analysis; Cellulose / metabolism; Kentucky; Lignin / metabolism; Methane / metabolism; North Carolina; Polysaccharides / metabolism; Refuse Disposal / methods; Waste Disposal Facilities
TL;DR:
The fraction of biogenic carbon that is not reactive in the landfill environment and therefore stored was derived for samples of excavated waste by measurement of the total organic carbon, its biogenic fraction, and the remaining methane potential.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Inquiry into Chemotherapy-induced p53 Activation in Cancer Cells as a Model for Teaching Signal Transduction
BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION, 41(6), 419–432.
author keywords: cancer; laboratory; cell signaling; p53
MeSH headings : Antineoplastic Agents, Phytogenic / pharmacology; Biochemistry / education; Blotting, Western; Cell Line, Tumor; Cell Survival / drug effects; Drug Therapy / methods; Etoposide / pharmacology; Flow Cytometry; Humans; Medical Laboratory Personnel / education; Microscopy, Fluorescence; Neoplasms / metabolism; Neoplasms / pathology; Phosphorylation / drug effects; Problem-Based Learning / methods; Reproducibility of Results; Research / education; Research / instrumentation; Research Design / standards; Research Report / standards; Signal Transduction / drug effects; Students; Teaching / methods; Tumor Suppressor Protein p53 / metabolism; Universities
TL;DR:
A new laboratory‐intensive course that teaches students the theory and techniques used to study cell signaling pathways as they conduct a hypothesis‐driven research project to elucidate the mechanism of breast cancer cell death caused by a cancer chemotherapeutic agent is developed and implemented.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2013 journal article
IL-17A Induces Signal Transducers and Activators of Transcription-6-Independent Airway Mucous Cell Metaplasia
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 48(6), 711–716.
author keywords: asthma; mucous cell metaplasia; IL-17A; STAT6; IL-13
MeSH headings : Adoptive Transfer; Animals; Bronchoalveolar Lavage Fluid / immunology; Female; Interleukin-13 / metabolism; Interleukin-17 / genetics; Interleukin-17 / metabolism; Lung / immunology; Lung / pathology; Metaplasia / immunology; Metaplasia / pathology; Metaplasia / virology; Mice; Mice, Inbred BALB C; Mice, Knockout; Mucus / metabolism; Neutrophils / metabolism; Ovalbumin / administration & dosage; Ovalbumin / immunology; Peptide Fragments / administration & dosage; Peptide Fragments / immunology; Receptors, Interleukin-17 / genetics; Receptors, Interleukin-17 / immunology; Receptors, Interleukin-17 / metabolism; Respiratory Syncytial Virus Infections / immunology; Respiratory Syncytial Virus Infections / pathology; Respiratory Syncytial Viruses / immunology; STAT1 Transcription Factor / genetics; STAT1 Transcription Factor / metabolism; STAT6 Transcription Factor / genetics; STAT6 Transcription Factor / metabolism; Th17 Cells / immunology; Transcriptional Activation
TL;DR:
It is hypothesized that IL-17A induces mucous cell metaplasia independent of STAT6, and this hypothesis was tested in two murine models in which increased IL- 17A protein expression is evident.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Hydrogen peroxide and extracellular signal-related kinase 1/2 pathway regulate ferritin levels in retinal pigmented and lens epithelial cells
Molecular Vision, 19, 2106–2112.
Source: NC State University Libraries
Added: August 6, 2018
2013 journal article
Expression of Fibroblast Growth Factor 9 in Normal Human Lung and Idiopathic Pulmonary Fibrosis
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 61(9), 671–679.
author keywords: smooth muscle cells; myofibroblast; metaplastic epithelium
MeSH headings : Adult; Cells, Cultured; Fibroblast Growth Factor 9 / analysis; Fibroblast Growth Factor 9 / metabolism; Humans; Idiopathic Pulmonary Fibrosis / metabolism; Idiopathic Pulmonary Fibrosis / pathology; Immunohistochemistry; Lung / metabolism; Lung / pathology; Lung / ultrastructure; Myocytes, Smooth Muscle / metabolism; Myocytes, Smooth Muscle / pathology; Myocytes, Smooth Muscle / ultrastructure; Myofibroblasts / metabolism; Myofibroblasts / pathology; Myofibroblasts / ultrastructure
TL;DR:
Lungs of IPF patients expressed FGF9 in a population of myofibroblasts within fibroblastic foci, hypertrophic and hyperplastic epithelium of airways and alveoli, and smooth muscle cells surrounding vessels embedded in thickened interstitium, demonstrating a potentially strong candidate for contributing to the progression of IPf.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2013 article
Environmental Pathobiology and Global Opportunities
Schmidt, S. P., Jokinen, M. P., Law, J. M., Pandiri, A. R., Weddle, D. L., Wolf, J. C., & Sills, R. C. (2013, September). VETERINARY PATHOLOGY, Vol. 50, pp. 733–734.
MeSH headings : Ecology / methods; Ecology / trends; Editorial Policies; Pathology, Veterinary / methods; Pathology, Veterinary / trends; Periodicals as Topic
TL;DR:
The establishment of a section on Environmental Pathobiology will provide opportunities for diagnosticians, pathologists, pathology residents, and scientists to learn and publish about current mechanistic research and various types of diagnostic methods used to assess and clarify disease processes caused by exposure to environmental contaminants.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Ecological epigenetics: an introduction to the symposium
Integrative and Comparative Biology, 53(2), 307–318.
Source: NC State University Libraries
Added: August 6, 2018
2013 journal article
Differentially expressed microRNAs and affected biological pathways revealed by modulated modularity clustering (MMC) analysis of human preeclamptic and IUGR placentas
Placenta, 34(7), 599–605.
author keywords: Placenta; Preeclampsia; IUGR; MiR-194; MiR-149
MeSH headings : Down-Regulation; Female; Fetal Growth Retardation / genetics; Fetal Growth Retardation / metabolism; Humans; MicroRNAs / biosynthesis; Placenta / metabolism; Pre-Eclampsia / genetics; Pre-Eclampsia / metabolism; Pregnancy; Transcriptome
TL;DR:
Modulated modularity clustering (MMC) allowed the elucidation of a molecular signature associated with preeclampsia and a subset of IUGR samples, which allowed the identification of genes, pathways, and microRNAs affected in these diseases.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, Crossref
Added: August 6, 2018
2013 journal article
Apheresis in three dogs weighing <14 kg
Veterinary Anaesthesia and Analgesia, 40(4), 403–409.
author keywords: apheresis; dog; fluid therapy; chemical restraint
MeSH headings : Anesthetics / pharmacology; Animals; Blood Component Removal / instrumentation; Blood Component Removal / methods; Blood Component Removal / veterinary; Body Weight; Dexmedetomidine / pharmacology; Dogs; Hypnotics and Sedatives / pharmacology; Lymphoma / therapy; Lymphoma / veterinary; Male; Propofol / pharmacology
TL;DR:
Dogs as small as 9.9 kg can successfully undergo apheresis with a variety of priming solutions, and Dexmedetomidine or propofol given as a CRI provides sufficient sedation for this procedure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref
Added: August 6, 2018
2013 journal article
The pharmacokinetics of cytarabine in dogs when administered via subcutaneous and continuous intravenous infusion routes
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 36(4), 408–411.
MeSH headings : Animals; Antimetabolites, Antineoplastic / administration & dosage; Antimetabolites, Antineoplastic / blood; Antimetabolites, Antineoplastic / pharmacokinetics; Area Under Curve; Cross-Over Studies; Cytarabine / administration & dosage; Cytarabine / blood; Cytarabine / pharmacokinetics; Dogs / blood; Dogs / metabolism; Half-Life; Infusions, Intravenous / veterinary; Injections, Subcutaneous / veterinary
TL;DR:
The steady state achieved with the cyTarabine CRI may produce a more prolonged exposure of cytarabine at cytotoxic levels in plasma compared to the concentrations after SC administration, as these are two routes of administration commonly employed in the treatment of meningitis of unknown etiology.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2013 journal article
Super Resolution Microscopy Reveals that Caveolin-1 Is Required for Spatial Organization of CRFB1 and Subsequent Antiviral Signaling in Zebrafish
PLoS ONE, 8(7), e68759.
Ed(s): C. Lamaze
MeSH headings : Animals; Caveolin 1 / metabolism; Cell Membrane / metabolism; Disease Resistance / immunology; Fish Diseases / immunology; Fish Diseases / metabolism; Fish Diseases / virology; Immunity, Innate / genetics; Interferons / metabolism; Protein Binding; Receptors, Interferon / metabolism; Signal Transduction; Zebrafish / immunology; Zebrafish / metabolism; Zebrafish / virology; Zebrafish Proteins / metabolism
TL;DR:
This response strongly suggests that CRFB1 organization within cav-1b-containing membrane domains is critical for IFN-mediated antiviral defense and presents a previously undescribed antiviral evasion strategy to alter IFN signaling and the antiviral immune response.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2013 journal article
Pharmacokinetics and thrombolytic effects of the recombinant tissue-type plasminogen activator in horses
BMC VETERINARY RESEARCH, 9.
author keywords: Alteplase; Recombinant tissue plasminogen activator; Thrombus; Clot formation; Hypercoagulopathy
MeSH headings : Animals; Area Under Curve; Female; Fibrinogen / analysis; Fibrinolytic Agents / administration & dosage; Fibrinolytic Agents / pharmacokinetics; Fibrinolytic Agents / therapeutic use; Half-Life; Horses / metabolism; Infusions, Intravenous / veterinary; Male; Partial Thromboplastin Time / veterinary; Prothrombin Time / veterinary; Thrombin Time / veterinary; Thrombosis / drug therapy; Thrombosis / veterinary; Tissue Plasminogen Activator / administration & dosage; Tissue Plasminogen Activator / pharmacokinetics; Tissue Plasminogen Activator / therapeutic use
TL;DR:
Findings indicate that a single dose of 1 mg/kg alteplase results in rt-PA plasma concentrations comparable to those in humans and might be sufficient for a thrombolytic therapy in horses.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Peptide Aptamers That Bind to Geminivirus Replication Proteins Confer a Resistance Phenotype to Tomato Yellow Leaf Curl Virus and Tomato Mottle Virus Infection in Tomato
JOURNAL OF VIROLOGY, 87(17), 9691–9706.
MeSH headings : Amino Acid Sequence; Aptamers, Peptide / genetics; Aptamers, Peptide / metabolism; Begomovirus / genetics; Begomovirus / pathogenicity; Begomovirus / physiology; DNA, Viral / genetics; DNA, Viral / metabolism; Geminiviridae / genetics; Geminiviridae / pathogenicity; Geminiviridae / physiology; Solanum lycopersicum / virology; Molecular Sequence Data; Phenotype; Plant Diseases / genetics; Plant Diseases / prevention & control; Plant Diseases / virology; Plants, Genetically Modified; Protein Binding; Two-Hybrid System Techniques; Viral Proteins / genetics; Viral Proteins / physiology; Virus Replication
TL;DR:
The efficacy of using Rep-binding peptide aptamers to develop crops that are resistant to diverse geminiviruses is established.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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