Works Published in 2018
Displaying works 141 - 160 of 192 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2018 journal article
Design and Functional Evaluation of a Dexterous Myoelectric Hand Prosthesis With Biomimetic Tactile Sensor
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING, 26(7), 1391–1399.
author keywords: Hand prosthesis; tactile sensor; tactile data driven grasping; multifingered prosthesis; myoelectric control
MeSH headings : Algorithms; Amputees; Biomechanical Phenomena; Electromyography / instrumentation; Electromyography / methods; Electronics; Feedback, Sensory; Fingers / innervation; Hand; Hand Strength; Healthy Volunteers; Humans; Prostheses and Implants; Prosthesis Design; Touch
TL;DR:
This paper presents the design, tactile sensor, characterization, and control system of a new dexterous myoelectric hand prosthesis to overcome the limitations of state-of-the-art myoeLECTric prostheses.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Clusters of midlife women identified by cognitive symptoms
MATURITAS, 110, 33–40.
author keywords: Cognition; Symptom; Cluster analysis; Middle aged; Women; Race/ethnicity
MeSH headings : Adult; Body Mass Index; Cluster Analysis; Cognition; Ethnicity; Factor Analysis, Statistical; Female; Health Services Accessibility; Health Status; Humans; Internet; Menopause / ethnology; Menopause / psychology; Middle Aged; Socioeconomic Factors; White People; Women's Health
TL;DR:
Racial/ethnic differences in midlife women's cognitive symptoms and multiple factors that might differently influence their cognitive symptoms need to be considered in health care for mid life women in menopausal transition.
(via Semantic Scholar)
www.ncbi.nlm.nih.gov (repository)
UN Sustainable Development Goal Categories
1. No Poverty
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Bacteria-Driven Hypoxia Targeting for Combined Biotherapy and Photothermal Therapy
ACS NANO, 12(6), 5995–6005.
author keywords: salmonella; polydopamine; hypoxia targeting; photothermal therapy; malignant melanoma
MeSH headings : Animals; Antineoplastic Agents / adverse effects; Antineoplastic Agents / metabolism; Antineoplastic Agents / pharmacology; Cell Survival / drug effects; Hypoxia / metabolism; Indoles / adverse effects; Indoles / metabolism; Indoles / pharmacology; Lasers; Melanoma, Experimental / metabolism; Melanoma, Experimental / pathology; Melanoma, Experimental / therapy; Mice; Phototherapy; Polymers / adverse effects; Polymers / metabolism; Polymers / pharmacology; Salmonella / growth & development; Salmonella / metabolism; Tissue Distribution; Tumor Cells, Cultured
TL;DR:
Both VNP and pDA potentiate the therapeutic ability of each other, resulting in a superior anticancer effect, which eliminated the tumors without relapse or metastasis with only one injection and laser irradiation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2018 review
Advances in liquid metals for biomedical applications
[Review of ]. CHEMICAL SOCIETY REVIEWS, 47(8), 2518–2533.
MeSH headings : Animals; Antineoplastic Agents / administration & dosage; Biocompatible Materials / chemistry; Biocompatible Materials / toxicity; Biosensing Techniques / methods; Drug Carriers / chemistry; Drug Carriers / toxicity; Gallium / chemistry; Humans; Metals / chemistry; Microfluidics / instrumentation; Microfluidics / methods; Nanostructures / chemistry; Neoplasms / diagnosis; Neoplasms / drug therapy; Photosensitizing Agents / chemistry; Photosensitizing Agents / therapeutic use
TL;DR:
This tutorial review introduces the common performances of liquid metals, highlights their featured properties, as well as summarizes various state-of-the-art bio-applications involving carriers for drug delivery, molecular imaging, cancer therapy and biomedical devices.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2018 review
Advances in glycosylation-mediated cancer-targeted drug delivery
[Review of ]. DRUG DISCOVERY TODAY, 23(5), 1126–1138.
MeSH headings : Animals; Drug Delivery Systems; Glycosylation; Humans; Neoplasms / drug therapy
TL;DR:
This review surveys a variety of glycosylation-mediated cancer-targeted drug nanocarriers as well as their applications for cancer therapy and discusses their challenges, opportunities, and future perspectives.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
A Lower-Back Robotic Exoskeleton
IEEE ROBOTICS & AUTOMATION MAGAZINE, 25(2), 95–106.
TL;DR:
Experimental results show that the exoskeleton can lower lumbar compression by reducing the need for muscular activity in the spine, and powering both HFE and HAA can effectively reduce the lumbr spinal loading user experience when lifting and lowering objects while in a twisted posture.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2018 journal article
3D conditional generative adversarial networks for high-quality PET image estimation at low dose
NEUROIMAGE, 174, 550–562.
author keywords: Positron emission tomography (PET); Generative adversarial networks (GANs); 3D conditional GANs (3D c-GANs); Low-dose PET; Image estimation
MeSH headings : Adult; Brain / diagnostic imaging; Deep Learning; Female; Humans; Image Processing, Computer-Assisted / methods; Male; Positron-Emission Tomography / methods; Radiation Dosage; Reproducibility of Results; Signal-To-Noise Ratio; Young Adult
TL;DR:
Experimental results show that the proposed 3D c‐GANs method outperforms the benchmark methods and achieves much better performance than the state‐of‐the‐art methods in both qualitative and quantitative measures.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
10. Reduced Inequalities
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Voluntary Control of Residual Antagonistic Muscles in Transtibial Amputees: Feedforward Ballistic Contractions and Implications for Direct Neural Control of Powered Lower Limb Prostheses
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING, 26(4), 894–903.
author keywords: Residual muscles; myoelectric control; lower limb amputee; powered prosthesis; postural control
MeSH headings : Adolescent; Adult; Aged; Amputees / psychology; Ankle / physiology; Artificial Limbs; Biomechanical Phenomena; Electromyography / statistics & numerical data; Electrophysiological Phenomena; Feedback, Physiological; Female; Humans; Lower Extremity; Male; Middle Aged; Muscle Contraction / physiology; Muscle, Skeletal / physiology; Prosthesis Design / methods; Psychomotor Performance; Recruitment, Neurophysiological; Task Performance and Analysis
TL;DR:
Results suggest that it is feasible for transtibial amputees to generate ballistic control signals using their residual muscles, and future work on volitional control of powered power ankle prostheses might consider anticipatory postural control based on ballistic-like residual muscle activation patterns and direct continuous proportional myoelectric control.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2018 journal article
PD-1 Blockade Cellular Vesicles for Cancer Immunotherapy
ADVANCED MATERIALS, 30(22).
author keywords: cancer immunotherapy; cell therapy; drug delivery; immune checkpoint blockade; nanomedicine
MeSH headings : Humans; Immunotherapy; Lymphocytes, Tumor-Infiltrating; Neoplasms / therapy; Programmed Cell Death 1 Receptor; T-Lymphocytes; Tumor Microenvironment
TL;DR:
E engineered cellular nanovesicles (NVs) presenting PD‐1 receptors on their membranes, which enhance antitumor responses by disrupting thePD‐1/PD‐L1 immune inhibitory axis, are reported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Mutagenesis Study of the Cytochrome c Subunit Responsible for the Direct Electron Transfer-Type Catalytic Activity of FAD-Dependent Glucose Dehydrogenase
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 19(4).
Contributors: Y. Yamashita *, N. Suzuki*, N. Hirose*, K. Kojima*, W. Tsugawa * & K. Sode n
author keywords: glucose dehydrogenase; direct electron transfer; cytochrome c; glucose sensor; biomedical engineering
MeSH headings : Amino Acid Sequence; Biocatalysis; Catalytic Domain / genetics; Cytochromes c / chemistry; Cytochromes c / genetics; Electrodes; Electrons; Enzyme Assays; Flavin-Adenine Dinucleotide / metabolism; Glucose 1-Dehydrogenase / metabolism; Mutagenesis / genetics; Mutant Proteins / metabolism; Solutions
TL;DR:
A mutagenesis investigation of the heme axial ligands was carried out to elucidate the electron transfer pathway to the electron mediators and/or the electrode, and two electron transfer pathways were proposed depending on the electron acceptors.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2018 journal article
Motor-like DNA motion due to an ATP-hydrolyzing protein under nanoconfinement
Scientific Reports, 8.
Source: NC State University Libraries
Added: August 6, 2018
2018 journal article
Improved muscle activation using proximal nerve stimulation with subthreshold current pulses at kilohertz-frequency
JOURNAL OF NEURAL ENGINEERING, 15(4).
author keywords: transcutaneous electrical nerve stimulation; electromyography; motor unit action potential; subthreshold stimulation; kilohertz-frequency
MeSH headings : Action Potentials / physiology; Adult; Electromyography / methods; Female; Humans; Male; Median Nerve / physiology; Muscle Contraction / physiology; Muscle, Skeletal / innervation; Muscle, Skeletal / physiology; Transcutaneous Electric Nerve Stimulation / methods; Ulnar Nerve / physiology; Young Adult
TL;DR:
The findings indicated that different nerve fibers were recruited asynchronously through summations of different numbers of subthreshold depolarizations in the HF mode, which was capable of activating the nerve fibers in a less synchronized way, which is more similar to the physiological activation pattern.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Hierarchical Nanoassemblies-Assisted Combinational Delivery of Cytotoxic Protein and Antibiotic for Cancer Treatment
NANO LETTERS, 18(4), 2294–2303.
author keywords: Drug delivery; protein therapy; radical polymerization; cancer stem-like cells; combination cancer therapy
MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / pharmacokinetics; Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / therapeutic use; Breast Neoplasms / drug therapy; Breast Neoplasms / pathology; Cell Line, Tumor; Cell Survival / drug effects; Delayed-Action Preparations / chemistry; Doxycycline / administration & dosage; Doxycycline / pharmacokinetics; Doxycycline / pharmacology; Doxycycline / therapeutic use; Drug Delivery Systems; Female; Humans; Mice; Nanostructures / chemistry; Neoplastic Stem Cells / drug effects; Ribonuclease, Pancreatic / administration & dosage; Ribonuclease, Pancreatic / pharmacokinetics; Ribonuclease, Pancreatic / pharmacology; Ribonuclease, Pancreatic / therapeutic use
TL;DR:
It is shown that a hierarchically assembled nanocomposite can self-adaptively transform its particulate property in response to endogenous tumor-associated signals to overcome the sequential barriers and achieve an enhanced antitumor efficacy by killing CSCs and bulk tumor cells synchronously.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Evoked haptic sensations in the hand via non-invasive proximal nerve stimulation
JOURNAL OF NEURAL ENGINEERING, 15(4).
Contributors: H. Huang n , H. Shin n, Z. Watkins n, Y. Zhu n & X. Hu n
author keywords: sensory feedback; electrical stimulation; peripheral nerve stimulation; haptic sensations
MeSH headings : Adult; Amputees / rehabilitation; Female; Hand / innervation; Hand / physiology; Humans; Male; Touch Perception / physiology; Transcutaneous Electric Nerve Stimulation / methods; Young Adult
TL;DR:
The elicitation of haptic sensations in the phantom hand of an amputee is a significant step in the development of the stimulation method, and provides insight into the future adaptation and implementation of prostheses with non-invasive sensory feedback to the users.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2018 journal article
Does local dynamic stability during unperturbed walking predict the response to balance perturbations? An examination across age and falls history
GAIT & POSTURE, 62, 80–85.
author keywords: Balance; Elderly; Lyapunov; Stability
MeSH headings : Accidental Falls / statistics & numerical data; Adult; Aged; Female; Humans; Locomotion / physiology; Male; Middle Aged; Postural Balance / physiology; Walking / physiology; Young Adult
TL;DR:
Predicting the response to balance perturbations in older fallers, at least that measured using local dynamic stability, likely requires measuring that response directly, and evidence is found that optical flow perturbation of sufficient amplitude appear capable of revealing independent effects of aging and falls history that are not otherwise apparent during normal, unperturbed walking.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Construction and characterization of flavin adenine dinucleotide glucose dehydrogenase complex harboring a truncated electron transfer subunit
ELECTROCHIMICA ACTA, 277, 276–286.
Contributors: J. Okuda-Shimazaki*, N. Loew n, N. Hirose n, K. Kojima*, K. Mori*, W. Tsugawa *, K. Sode n
author keywords: Direct electron transfer; Truncated electron transfer subunit; Heme c; Glucose dehydrogenase; Glucose sensing
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2018 journal article
Association between kinesiophobia and walking gait characteristics in physically active individuals with anterior cruciate ligament reconstruction
GAIT & POSTURE, 64, 220–225.
author keywords: Ground reaction force; Knee extension moment; Knee flexion excursion; Limb symmetry index; Tampa Scale for Kinesiophobia
MeSH headings : Adolescent; Adult; Anterior Cruciate Ligament Injuries / psychology; Anterior Cruciate Ligament Injuries / surgery; Anterior Cruciate Ligament Reconstruction / adverse effects; Anterior Cruciate Ligament Reconstruction / psychology; Biomechanical Phenomena; Cross-Sectional Studies; Female; Gait / physiology; Humans; Kinetics; Knee Joint / physiopathology; Knee Joint / surgery; Lower Extremity / physiopathology; Male; Phobia, Social / epidemiology; Phobia, Social / etiology; Range of Motion, Articular / physiology; Walking / physiology; Walking / psychology; Walking Speed / physiology; Young Adult
TL;DR:
Data do not support that kinesiophobia is a critical factor contributing to walking gait characteristics in physically active individuals with ACLR.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty
(OpenAlex)
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Aging effects on leg joint variability during walking with balance perturbations
GAIT & POSTURE, 62, 27–33.
author keywords: Visual feedback; Elderly; Gait; Stability; Falls; Kinematics
MeSH headings : Adult; Aged; Aging / physiology; Ankle Joint / physiology; Female; Gait / physiology; Healthy Volunteers; Hip Joint / physiology; Humans; Knee Joint / physiology; Male; Postural Balance / physiology; Range of Motion, Articular / physiology; Walking / physiology; Young Adult
TL;DR:
It is found that leg joint variability during walking is gait phase-dependent, with step-to-step adjustments occurring predominantly during push-off and early swing, and perturbations elicited larger and more pervasive increases in all joint kinematic outcome measures in older adults.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Advances in bioresponsive closed-loop drug delivery systems
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 544(2), 350–357.
author keywords: Closed-loop; Drug delivery; Bioresponsive; Glucose-responsive; Enzyme-responsive
MeSH headings : Anticoagulants / administration & dosage; Diabetes Mellitus, Type 1 / blood; Diabetes Mellitus, Type 1 / drug therapy; Drug Delivery Systems / methods; Feedback, Physiological / drug effects; Homeostasis / drug effects; Humans; Hypoglycemic Agents / administration & dosage; Thrombosis / blood; Thrombosis / drug therapy
TL;DR:
The recent advances in bioresponsive closed‐loop drug delivery systems, including glucose‐responsive, enzyme‐activated, and other biosignal‐mediated delivery systems are surveyed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2018 review
Targeting aging for disease modification in osteoarthritis
[Review of ]. CURRENT OPINION IN RHEUMATOLOGY, 30(1), 101–107.
author keywords: aging; cell senescence; cell signaling; mitochondria; reactive oxygen species
MeSH headings : Aging / metabolism; Animals; Antioxidants / metabolism; Cellular Senescence; Gene Expression Regulation; Humans; Mitochondria / metabolism; NF-E2-Related Factor 2 / metabolism; Osteoarthritis / drug therapy; Osteoarthritis / metabolism; Oxidative Stress; Reactive Oxygen Species / metabolism; Signal Transduction
TL;DR:
Preclinical studies suggest that targeting cellular senescence and/or mitochondrial dysfunction and the effects of excessive ROS may lead to novel interventions that could slow the progression of osteoarthritis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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