Works Published in 2023
Displaying works 41 - 60 of 133 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2023 journal article
Rare variants in <i>CAPN2</i> increase risk for isolated hypoplastic left heart syndrome
HUMAN GENETICS AND GENOMICS ADVANCES, 4(4).
TL;DR:
The findings show that iHLHS is typically not a Mendelian condition, demonstrate that CAPN2 variants increase risk of i HLHS, and identify a novel pathway involved in HLHS pathogenesis.
(via Semantic Scholar)
doi.org (publisher)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: October 16, 2023
2023 journal article
Caveolin-1-derived peptide attenuates cigarette smoke-induced airway and alveolar epithelial injury.
American Journal of Physiology. Lung Cellular and Molecular Physiology.
TL;DR:
Treatment of patients with COPD or mice with CS-LI with a seven amino acid caveolin-1 scaffolding domain peptide (CSP7) reduced mucus hypersecretion in AECs and improved AT2 cell viability and significantly improved lung function.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: October 15, 2023
2023 article
Assessing the Toxicity of Sea Salt to Early Life Stages of Freshwater Mussels: Implications for Sea Level Rise in Coastal Rivers
Mciver II, J. K., Cope, W. G., Bringolf, R. B., Kwak, T. J., Watson, B., Maynard, A., & Mair, R. (2023, September 20). ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, Vol. 9.
author keywords: Sea salt toxicity; Climate change; Freshwater mussel; Median effect concentration (EC50); Acute toxicity; Salinization
TL;DR:
The results show that acute exposure to sea salt adversely affects freshwater mussels viability, particularly glochidia, and this information can be used to enhance freshwater mussel conservation strategies in regions that are or will be impacted by climate‐induced sea level rise and associated freshwater salinization.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(Web of Science; OpenAlex)
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: October 10, 2023
2023 journal article
Estimation of the Half-Lives of Recently Detected Per- and Polyfluorinated Alkyl Ethers in an Exposed Community
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 57(41), 15348–15355.
author keywords: exposure; PFAS; water; humans; environment; toxicokinetic modeling
TL;DR:
These fluoroethers had biological half-Lives longer than published half-lives for PFHxA and PFHpA but shorter than those for PFOA andPFOS (800-1200 days).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: October 7, 2023
2023 journal article
A vision for safer food contact materials: Public health concerns as drivers for improved testing
ENVIRONMENT INTERNATIONAL, 180.
author keywords: Food packaging; Hazard assessment; Chronic disease; Chemical safety
TL;DR:
The safety of FCMs may be improved by testing the overall migrate, including non-intentionally added substances (NIAS), of finished food contact articles, and expanding toxicological testing beyond genotoxicity to multiple endpoints associated with non-communicable diseases relevant to human health.
(via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: September 26, 2023
2023 journal article
Development of machine learning algorithms to estimate maximum residue limits for veterinary medicines
FOOD AND CHEMICAL TOXICOLOGY, 179.
author keywords: Unestablished MRL; Veterinary drugs; Machine learning; International market and trade; Published commodity (animal organ); Data resampling techniques
TL;DR:
This study demonstrates unestablished MRLs can be reliably predicted for under-represented food commodity groups using machine learning (ML) and provides the first study to apply ML algorithms in regulatory food animal medicine.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: September 25, 2023
2023 article
Comparative analysis of sucrose-embedding for whole-body zebrafish MSI by IR-MALDESI
Wang, M. F., Ritter, M. M., Kullman, S. W., & Muddiman, D. C. (2023, August 29). ANALYTICAL AND BIOANALYTICAL CHEMISTRY, Vol. 8.
author keywords: IR-MALDESI; Mass spectrometry imaging; Sucrose; PFA; Zebrafish
TL;DR:
Danio rerio, or zebrafish, are model organisms for various disease states and can be imaged as a multi-organ sample to analyze morphological and metabolomic preservation as a result of sample preparation to compare sucrose-embedding with paraformaldehyde fixation against conventional fresh-frozen sample preparation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: September 25, 2023
2023 journal article
Biomolecular Minerals and Volcanic Glass Bio-Mimics to Control Adult Sand Flies, the Vector of Human Leishmania Protozoan Parasites
BIOMOLECULES, 13(8).
author keywords: industrial biomolecular minerals; sand flies; Imergard; Celite
TL;DR:
Proof of concept was established for the use of these biominerals for sand fly and leishmaniasis disease control and scanning electron microscopy of dead sand flies showed high coating levels of Celite only on the sides of the thorax and on the tarsi, suggesting an alternative mode of action for mechanical insecticides.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: September 25, 2023
2023 article
Deep autoencoder-based behavioral pattern recognition outperforms standard statistical methods in high-dimensional zebrafish studies
Green, A. J., Truong, L., Thunga, P., Leong, C., Hancock, M., Tanguay, R. L., & Reif, D. M. (2023, September 17).
TL;DR:
It is demonstrated that a deep autoencoder using raw behavioral tracking data from zebrafish toxicity screens outperforms conventional statistical methods, resulting in a comprehensive evaluation of behavioral data.
(via Semantic Scholar)
Source: ORCID
Added: September 18, 2023
2023 journal article
Detection of Orientia spp. Bacteria in Field-Collected Free-Living Eutrombicula Chigger Mites, United States
EMERGING INFECTIOUS DISEASES, 29(8), 1676–1679.
TL;DR:
The molecular detection of Orientia species in free-living Eutrombicula chiggers collected in an area in North Carolina, USA, to which spotted fever group rickettsiae infections are endemic is reported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: September 11, 2023
2023 journal article
PFAS levels in paired drinking water and serum samples collected from an exposed community in Central North Carolina
SCIENCE OF THE TOTAL ENVIRONMENT, 895.
author keywords: Per-andpolyfluoroalkyl substances; PFAS; Drinking water; Serum; Human health outcomes
TL;DR:
Extensive exposure to PFAS in Pittsboro is revealed and associations with clinical blood markers are revealed, suggesting potential health impacts in community residents.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: September 11, 2023
2023 journal article
Acaricidal Biominerals and Mode-of-Action Studies against Adult Blacklegged Ticks, Ixodes scapularis
MICROORGANISMS, 11(8).
author keywords: mechanical insecticides; ticks; Imergard; Celite; repellency
TL;DR:
Although the assumed mode of action of Imergard and Celite is dehydration, the minerals are not hygroscopic, there was no evidence of cuticle damage, and death occurred in as little as 2 h, suggesting minimal abrasive action of the cuticle.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: September 11, 2023
2023 article
The dirty side of clean energy: Lithium ion batteries as a source of PFAS in the environment
Guelfo, J., Ferguson, P., Beck, J., Chernick, M., Doria-Manzur, A., Faught, P., … Shojaei, M. (2023, August 1).
Source: ORCID
Added: September 9, 2023
2023 article
Assessing Per- and Polyfluoroalkyl Substances (PFAS) in Fish Fillet Using Non-Targeted Analyses
Boatman, A. K., Chappel, J. R., Polera, M. E., Dodds, J. N., Belcher, S. M., & Baker, E. S. (2023, September 5).
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: ORCID
Added: September 6, 2023
2023 article
Role of hormones in substance use disorders
Rissman, E. F., & Lynch, W. J. (2023, August 10). NEUROENDOCRINOLOGY.
TL;DR:
A group of primary-literature papers solicited from many of the leading addiction laboratories in the world are assembled, highlighting different drug classes, hormones, levels of analysis, and animal models in the hope that this “ wide angle ” approach provides some overarching conclusions on common mechanisms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: September 5, 2023
2023 article
Application of Ion Mobility Spectrometry-Mass Spectrometry for Compositional Characterization and Fingerprinting of a Library of Diverse Crude Oil Samples
Cordova, A. C., Dodds, J. N., Tsai, H.-H. D., Lloyd, D. T., Roman-Hubers, A. T., Wright, F. A., … Rusyn, I. (2023, August 22). ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY.
author keywords: Analytical chemistry; Environmental chemistry; Hazard; risk assessment; Mixtures; Oil spills
TL;DR:
It is found that IMS-MS data has complementary advantages for fingerprinting and characterization of diverse crude oils and that the proposed polycyclic aromatic hydrocarbon (PAH) biomarkers can be used for rapid exposure characterization.
(via Semantic Scholar)
Source: Web Of Science
Added: September 5, 2023
2023 journal article
Analysis of reproducibility and robustness of a renal proximal tubule microphysiological system OrganoPlate 3-lane 40 for in vitro studies of drug transport and toxicity
TOXICOLOGICAL SCIENCES.
author keywords: kidney; in vitro models; validation
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Web Of Science
Added: September 5, 2023
2023 article
The Effects of Long-term, Low-dose beta-N-methylamino-L-alanine (BMAA) Exposures in Adult SODG93R (Aug, 10.1007/s12640-023-00658-z, 2023)
Weeks, R. D., Banack, S. A., Howell, S., Thunga, P., Metcalf, J. S., Green, A. J., … Planchart, A. (2023, August 24). NEUROTOXICITY RESEARCH, Vol. 8.
Sources: Web Of Science, NC State University Libraries
Added: September 5, 2023
2023 journal article
Factors associated with per- and polyfluoroalkyl substances (PFAS) serum concentrations in residents of New Hanover County, North Carolina: The GenX exposure study
ENVIRONMENTAL RESEARCH, 237.
author keywords: Per-and polyfluoroalkyl substances (PFAS); Fluoroethers; Contaminated drinking water; Environmental exposure predictors
TL;DR:
It is shown that drinking water is a primary source for serum PFAS concentrations among New Hanover County residents and years of residence in the lower Cape Fear Region as a surrogate for water consumption were important for both the association and predictive investigations.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: September 4, 2023
2023 article
Ancient fish lineages illuminate toll-like receptor diversification in early vertebrate evolution
Carlson, K. B., Nguyen, C., Wcisel, D. J., Yoder, J. A., & Dornburg, A. (2023, August 9). IMMUNOGENETICS, Vol. 8.
author keywords: Vertebrate; TLR; Immunogenetics; Evolution; Actinopterygii; Polypterus senegalus
TL;DR:
This work investigates the diversification of vertebrate Toll-like receptors (TLRs), one of the most ancient and well conserved innate immune receptor families found across the Tree of Life, integrating genomic data that represent all major vertebrate lineages with new transcriptomic data from Polypteriformes, the earliest diverging ray-finned fish lineage.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 28, 2023
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