Works Published in 2014
Displaying works 61 - 80 of 143 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2014 journal article
Erratum to Incorporating human dosimetry and exposure into High-throughput in Vitro Toxicity Screening [Toxicological sciences 137, 2, (2014), 499]
Toxicological Sciences, 137(2).
Contributors: D. Rotroff, B. Wetmore, D. Dix, S. Ferguson, H. Clewell, K. Houck, E. LeCluyse, M. Andersen
academic.oup.com (publisher PDF)
Source: ORCID
Added: May 14, 2019
2014 conference paper
Pharmaceuticals in the environment: Review of current disposal practices for medications and the influence of public perception on environmental risks.
NC AWWA-WEA Annual Conference.
Source: NC State University Libraries
Added: August 6, 2018
2014 book
Source: NC State University Libraries
Added: August 6, 2018
2014 journal article
C/EBP alpha regulates CRL4(Cdt2)-mediated degradation of p21 in response to UVB-induced DNA damage to control the G(1)/S checkpoint
CELL CYCLE, 13(22), 3602–3610.
author keywords: C/EBP alpha; CRL4(Cdt2); G(1)/S DNA damage checkpoint; keratinocytes; p21
MeSH headings : Animals; CCAAT-Enhancer-Binding Protein-alpha / genetics; CCAAT-Enhancer-Binding Protein-alpha / metabolism; Cell Cycle Checkpoints / genetics; Cell Cycle Checkpoints / radiation effects; Cyclin-Dependent Kinase Inhibitor p21 / metabolism; DNA Damage / genetics; DNA Damage / radiation effects; G1 Phase Cell Cycle Checkpoints / genetics; Keratinocytes / metabolism; Keratinocytes / radiation effects; Mice; Nuclear Proteins / genetics; Nuclear Proteins / metabolism; Proteolysis; Ubiquitin-Protein Ligases / genetics; Ubiquitin-Protein Ligases / metabolism; Ultraviolet Rays; p21-Activated Kinases / genetics; p21-Activated Kinases / metabolism
TL;DR:
Findings reveal C/EBPα regulates G1/S cell cycle arrest in response to DNA damage via the control of CRL4Cdt2 mediated degradation of p21.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2014 journal article
Test driving ToxCast: endocrine profiling for 1858 chemicals included in phase II
CURRENT OPINION IN PHARMACOLOGY, 19, 145–152.
Contributors: D. Filer*, H. Patisaul n , T. Schug*, D. Reif n & K. Thayer *
MeSH headings : Animals; Databases, Factual; Endocrine Disruptors / toxicity; High-Throughput Screening Assays; Humans; Models, Theoretical; Risk Assessment; United States; United States Environmental Protection Agency
TL;DR:
Results from this exercise suggest the spectrum of environmental chemicals with potential endocrine activity is much broader than indicated, and that some aspects of endocrine disruption are not fully covered in ToxCast.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2014 journal article
Is Helicobacter Pylori an endogenous source of diethyl phthalate in humans?
Environmental Research, 134, 402–404.
author keywords: Diethyl phthalate; Monoethyl phthalate; Helicobacter pylori; NHANES; Microbiome
MeSH headings : Adolescent; Adult; Female; Helicobacter pylori / metabolism; Humans; Male; Middle Aged; Phthalic Acids / metabolism; Young Adult
TL;DR:
Results suggest that HP may be an endogenous source of DEP in some populations, and MEP levels were higher in individuals with HP seropositivity, however the association differed by race.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Integrative Genetic Analysis of Allergic Inflammation in the Murine Lung
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 51(3), 436–445.
author keywords: allergic airway disease; systems genetics; gene expression quantitative trait loci
MeSH headings : Animals; Antigens, Dermatophagoides / immunology; Bronchial Hyperreactivity / immunology; Dermatophagoides pteronyssinus / metabolism; Disease Models, Animal; Gene Expression Regulation; Genetics; Hypersensitivity / immunology; Hypersensitivity / metabolism; Immunoglobulin E / blood; Inflammation; Lung / immunology; Lung / metabolism; Male; Mice; Phenotype; Quantitative Trait Loci; Respiratory Hypersensitivity / immunology
TL;DR:
The results demonstrate that hallmark allergic airway disease phenotypes are associated with distinct genetic loci on Chrs 4 and 11, and that gene expression in the allergically inflamed lung is controlled by both cis and trans regulatory factors.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Functional diversification of vitamin D receptor paralogs in teleost fish after a whole genome duplication event
Endocrinology, 155(12), 4641–4654.
MeSH headings : Animals; Calcitriol / metabolism; Evolution, Molecular; Fish Proteins / genetics; Fish Proteins / metabolism; Gene Duplication; Genome; Nuclear Receptor Coactivators / metabolism; Oryzias; Receptors, Calcitriol / genetics; Receptors, Calcitriol / metabolism; Retinoid X Receptors / metabolism; Zebrafish
TL;DR:
The results imply that functional differences between VDRα and VDRβ occurred early in teleost evolution because they are conserved between distantly related species, and suggest that the observed differences may be associated with differential protein-protein interactions between the VDR paralogs and coactivators.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018
2014 journal article
Definition of the Cattle Killer Cell Ig-like Receptor Gene Family: Comparison with Aurochs and Human Counterparts
JOURNAL OF IMMUNOLOGY, 193(12), 6016–6030.
MeSH headings : Animals; Cattle; Chromosome Mapping; Chromosomes, Mammalian; Cloning, Molecular; Evolution, Molecular; Gene Library; Genetic Loci; Genome; Haplotypes; Humans; Immunoglobulins / genetics; Molecular Sequence Data; Multigene Family; Phenotype; Phylogeny; Receptors, IgG / metabolism; Receptors, KIR / classification; Receptors, KIR / genetics; Receptors, KIR / metabolism; Receptors, Natural Killer Cell / metabolism; Sequence Analysis, DNA; Signal Transduction; Telomere
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Accuracy of residential geocoding in the Agricultural Health Study
International Journal of Health Geographics, 13(1), 37.
author keywords: Geocoding; Positional error; Rural location; Environmental exposure assessment; Accuracy
MeSH headings : Agriculture / statistics & numerical data; Cohort Studies; Environmental Exposure / analysis; Environmental Exposure / statistics & numerical data; Female; Geographic Mapping; Health Status; Humans; Iowa / epidemiology; Male; North Carolina / epidemiology; Pesticides; Prospective Studies
TL;DR:
It is suggested that where E911 locations are available, they offer an improvement upon address-matched geocodes for rural addresses, and that exposure misclassification resulting from positional error can be minimized when known coordinates are available to test alternative data and methods.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Urinary Tetrabromobenzoic Acid (TBBA) as a Biomarker of Exposure to the Flame Retardant Mixture Firemaster ® 550
Environmental Health Perspectives, 122(9), 963–969.
MeSH headings : Adult; Aged; Animals; Biomarkers / metabolism; Bromobenzoates / urine; Dust / analysis; Environmental Exposure / analysis; Environmental Pollutants / urine; Female; Flame Retardants / metabolism; Hand; Humans; Male; Mass Spectrometry / methods; Middle Aged; Organophosphates / urine; Phthalic Acids / urine; Polybrominated Biphenyls / urine; Rats
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Transcriptome of the Female Synganglion of the Black-Legged Tick Ixodes scapularis (Acari: Ixodidae) with Comparison between Illumina and 454 Systems
PLOS ONE, 9(7).
MeSH headings : Animals; Female; Ganglia, Invertebrate / metabolism; Ixodes / genetics; Ixodes / metabolism; Neuropeptides / genetics; Neuropeptides / metabolism; Neurotransmitter Agents / genetics; Neurotransmitter Agents / metabolism; Polymerase Chain Reaction / methods; Receptors, Neurotransmitter / genetics; Receptors, Neurotransmitter / metabolism; Transcriptome
TL;DR:
The diversity of messages predicting important genes identified in this study offers a valuable resource useful for understanding how the tick synganglion regulates important physiological functions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2014 journal article
The effect of breed and sex on sulfamethazine, enrofloxacin, fenbendazole and flunixin meglumine pharmacokinetic parameters in swine
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 37(6), 531–541.
MeSH headings : Animals; Anti-Infective Agents / blood; Anti-Infective Agents / pharmacokinetics; Anti-Inflammatory Agents, Non-Steroidal / blood; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Antinematodal Agents / blood; Antinematodal Agents / pharmacokinetics; Benzimidazoles / blood; Ciprofloxacin / blood; Clonixin / analogs & derivatives; Clonixin / blood; Clonixin / pharmacokinetics; Enrofloxacin; Female; Fenbendazole / blood; Fenbendazole / pharmacokinetics; Fluoroquinolones / blood; Fluoroquinolones / pharmacokinetics; Male; Sex Factors; Species Specificity; Sulfamethazine / analogs & derivatives; Sulfamethazine / blood; Sulfamethazine / pharmacokinetics; Swine / metabolism
TL;DR:
Whether drug clearance differs across genetic backgrounds and sex for sulfamethazine, enrofloxacin, fenbendazole and flunixin meglumine is determined to determine the degree of additive genetic variation utilizing a larger population.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Soy but not bisphenol A (BPA) induces hallmarks of polycystic ovary syndrome (PCOS) and related metabolic co-morbidities in rats
REPRODUCTIVE TOXICOLOGY, 49, 209–218.
author keywords: Phytoestrogens; Genistein; Endocrine disruptors; Ovary; Development
MeSH headings : Animals; Benzhydryl Compounds / adverse effects; Diet / adverse effects; Endocrine Disruptors / adverse effects; Female; Ovary / drug effects; Ovary / pathology; Phenols / adverse effects; Polycystic Ovary Syndrome / chemically induced; Polycystic Ovary Syndrome / pathology; Pregnancy; Rats; Rats, Wistar; Soy Foods / adverse effects; Testosterone / blood
TL;DR:
Lifetime exposure to a soy diet, containing endocrine active phytoestrogens, but not developmental exposure to the endocrine disrupting monomer bisphenol A (BPA), can induce key features of PCOS in the rat, results which support the hypothesis that hormonally active diets may contribute to risk when consumed throughout gestation and post-natal life.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2014 journal article
Single-Nucleotide Polymorphism Data Support the General Unrelatedness of the Males in the Agricultural Health Study
Cancer Epidemiology Biomarkers & Prevention, 23(10), 2192–2195.
MeSH headings : Agriculture; Case-Control Studies; Cohort Studies; Consanguinity; Gene-Environment Interaction; Humans; Male; Occupational Exposure; Polymorphism, Single Nucleotide; Principal Component Analysis; Research Design
TL;DR:
This analysis rejects the hypothesis that individuals in the case–control study of prostate cancer exhibit cryptic relatedness, and these findings are important for all subsequent analyses of gene–environment interactions in the AHS.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Polymers for the stabilization and delivery of proteins topically and per os to the insect hemocoel through conjugation with aliphatic polyethylene glycol
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 115, 58–66.
author keywords: Insulin; Heliothis virescens; Tobacco budworm; PEGylation; Polyethylene glycol; Protein delivery
MeSH headings : Animals; Cattle; Drug Delivery Systems / methods; Hemolymph / metabolism; Insulin / chemistry; Insulin / metabolism; Larva / growth & development; Larva / metabolism; Moths / growth & development; Moths / metabolism; Polyethylene Glycols / chemistry; Polymers / chemistry; Polymers / metabolism; Protein Stability; Serum Albumin, Bovine / chemistry; Serum Albumin, Bovine / metabolism
TL;DR:
Co-feeding of aliphatic polyethylene glycol (PEG), phospholipase A2, anionic and ionic detergents, and amphipathic glycoside with bovine serum albumin as a model protein to fourth stadium tobacco budworms, Heliothis virescens, did not affect the levels of BSA in the hemolymph.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2014 journal article
Phytoremediation of a Petroleum-Hydrocarbon Contaminated Shallow Aquifer in Elizabeth City, North Carolina, USA
Remediation Journal, 24(2), 29–46.
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Pesticide use and incident diabetes among wives of farmers in the Agricultural Health Study
Occupational and Environmental Medicine, 71(9), 629–635.
Contributors: A. Starling *, D. Umbach *, F. Kamel*, S. Long*, D. Sandler * & J. Hoppin n
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Diabetes Mellitus / epidemiology; Diabetes Mellitus / etiology; Female; Humans; Incidence; Iowa / epidemiology; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Organophosphates / toxicity; Pesticides / toxicity; Proportional Hazards Models; Spouses; Young Adult
TL;DR:
Results are consistent with previous studies reporting an association between specific organochlorines and diabetes and add to growing evidence that certain organophosphates also may increase risk, though attenuated compared with separate models.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Genomic profiling reveals extensive heterogeneity in somatic DNA copy number aberrations of canine hemangiosarcoma
CHROMOSOME RESEARCH, 22(3), 305–319.
author keywords: canine; chromosome; hemangiosarcoma; comparative genomic hybridization (CGH)
MeSH headings : Animals; Breeding; Comparative Genomic Hybridization; DNA Copy Number Variations / genetics; Dog Diseases / genetics; Dogs; Gene Amplification; Gene Expression Profiling; Genetic Heterogeneity; Genome; Hemangiosarcoma / genetics; Hemangiosarcoma / veterinary; Penetrance; Vascular Endothelial Growth Factor A / genetics
TL;DR:
Analysis of genome-wide microarray-based somatic DNA copy number profiling of 75 primary intra-abdominal hemangiosarcomas from five popular dog breeds supports prior transcriptional studies suggesting that the clinical heterogeneity of this cancer may reflect the existence of multiple, molecularly distinct subtypes of canine hemangiusarcoma.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Fertilization of Radishes, Tomatoes, and Marigolds Using a Large-Volume Atmospheric Glow Discharge
PLASMA CHEMISTRY AND PLASMA PROCESSING, 34(6), 1271–1290.
Contributors: A. Lindsay n, B. Byrns n, W. King n, A. Andhvarapou n, J. Fields n, D. Knappe n , W. Fonteno n, S. Shannon n
author keywords: Large-volume glow; Atmospheric pressure plasma; Fertilization; Reactive nitrogen and oxygen species
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
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