Works Published in 2006

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Displaying works 61 - 80 of 96 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2006 journal article

Early growth response gene-1 regulates hypoxia-induced expression of tissue factor in glioblastoma multiforme through hypoxia-inducible factor-1-independent mechanisms

CANCER RESEARCH, 66(14), 7067–7074.

MeSH headings : Cell Hypoxia / physiology; Cell Line, Tumor; Early Growth Response Protein 1 / biosynthesis; Early Growth Response Protein 1 / genetics; Glioblastoma / genetics; Glioblastoma / metabolism; Humans; Hypoxia-Inducible Factor 1 / biosynthesis; Hypoxia-Inducible Factor 1 / genetics; NF-kappa B / biosynthesis; NF-kappa B / genetics; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun / biosynthesis; Proto-Oncogene Proteins c-jun / genetics; Sp1 Transcription Factor / biosynthesis; Sp1 Transcription Factor / genetics; Thromboplastin / biosynthesis; Thromboplastin / genetics; Transcription Factor AP-1 / biosynthesis; Transcription Factor AP-1 / genetics; Transfection; Up-Regulation; Vascular Endothelial Growth Factor A / genetics
TL;DR: It is concluded that hypoxic up-regulation of tissue factor in glioblastoma multiforme cells depends largely on Egr-1 and is independent of HIF-1. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Differential Muc2 and Muc5ac secretion by stimulated guinea pig tracheal epithelial cells in vitro

Respiratory Research, 7, 35.

By: B. Chorley, A. Crews, Y. Li, K. Adler, M. Minnicozzi & L. Martin

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Changes in tumour oxygenation during fractionated hyperthermia and radiation therapy in spontaneous canine sarcomas

INTERNATIONAL JOURNAL OF HYPERTHERMIA, 22(5), 365–373.

author keywords: hyperthermia; radiation therapy; dog; oxygen measurements
MeSH headings : Animals; Cell Hypoxia / physiology; Cell Hypoxia / radiation effects; Combined Modality Therapy / methods; Combined Modality Therapy / veterinary; Dog Diseases / metabolism; Dog Diseases / therapy; Dogs; Hyperthermia, Induced / methods; Hyperthermia, Induced / veterinary; Oxygen / analysis; Oxygen / metabolism; Sarcoma / metabolism; Sarcoma / therapy; Sarcoma / veterinary
TL;DR: There was an increase in oxygenation in tumours with low pre-treatment oxygenation that persisted throughout treatment, an advantageous hyperthermia effect as it may lead to increased radiation cell killing at each fraction. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2006 article

Annotation of the Affymetrix(1) porcine genome microarray

Tsai, S., Cassady, J. P., Freking, B. A., Nonneman, D. J., Rohrer, G. A., & Piedrahita, J. A. (2006, August). ANIMAL GENETICS, Vol. 37, pp. 423–424.

MeSH headings : Animals; DNA Probes; Gene Expression Profiling; Genomics; Humans; Oligonucleotide Array Sequence Analysis; Sequence Homology, Nucleic Acid; Swine / genetics
TL;DR: The strategy presented here is a strategy for improving the annotation of this microarray, which is minimally annotated on the basis of full-length porcine cDNA sequence. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Role for retinoid signaling in left–right asymmetric digestive organ morphogenesis

Developmental Dynamics, 235(8), 2266–2275.

By: K. Lipscomb*, C. Schmitt*, A. Sablyak*, J. Yoder n & N. Nascone-Yoder n

author keywords: retinoic acid; RALDH2; CYP26A1; gut; looping; malrotation; Xenopus; biliary atresia; annular pancreas
MeSH headings : Aldehyde Dehydrogenase 1 Family; Aldehyde Oxidase / genetics; Animals; Body Patterning; Cytochrome P-450 Enzyme System / genetics; Digestive System / growth & development; Digestive System / metabolism; Morphogenesis; Oxidoreductases / genetics; Receptors, Retinoic Acid / metabolism; Retinal Dehydrogenase; Retinoic Acid 4-Hydroxylase; Retinoids / metabolism; Signal Transduction; Xenopus Proteins / genetics; Xenopus laevis / genetics; Xenopus laevis / growth & development; Xenopus laevis / metabolism
TL;DR: It is shown that the genes for retinaldehyde dehydrogenase and a retinoic acid hydroxylase are expressed in complementary patterns in the Xenopus gut during looping, likely to play a critical role in asymmetric gut tube morphogenesis and may underlie the etiology of several clinically relevant defects in the digestive system. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2006 journal article

Identification of eggshell membrane proteins and purification of ovotransferrin and beta-NAGase from hen egg white

PROTEIN JOURNAL, 25(1), 71–81.

author keywords: beta-N-acetylglucosaminidase; ovotransferrin; isoelectric focusing; SDS-PAGE; eggshell membrane; hen egg white
MeSH headings : Acetylglucosaminidase / analysis; Acetylglucosaminidase / isolation & purification; Animals; Anti-Bacterial Agents / analysis; Chickens; Chromatography, Ion Exchange; Conalbumin / analysis; Conalbumin / isolation & purification; Egg Proteins / chemistry; Electrophoresis, Polyacrylamide Gel; Isoelectric Focusing; Membrane Proteins / chemistry; Muramidase / analysis; Ovum / chemistry; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
TL;DR: Attempts to purify active fractions of β-N-acetylglucosaminidase, lysozyme and ovotransferrin from the ESM proved somewhat limited and will be required in order to fully elucidate the mechanism responsible for the antimicrobial properties associated with the E SM. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Extracellular pH and P-31 magnetic resonance spectroscopic variables are related to outcome in canine soft tissue sarcomas treated with thermoradiotherapy

CLINICAL CANCER RESEARCH, 12(19), 5733–5740.

By: M. Lora-Michiels*, D. Yu*, L. Sanders*, J. Poulson*, C. Azuma*, B. Case n, Z. Vujaskovic*, D. Thrall n, H. Charles*, M. Dewhirst*

MeSH headings : Animals; Combined Modality Therapy; Disease Models, Animal; Dog Diseases / pathology; Dog Diseases / therapy; Dogs; Female; Hydrogen-Ion Concentration; Hyperthermia, Induced; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Phosphorus Isotopes; Prospective Studies; Radiotherapy Dosage; Sarcoma / pathology; Sarcoma / therapy; Sarcoma / veterinary; Soft Tissue Neoplasms / pathology; Soft Tissue Neoplasms / therapy; Soft Tissue Neoplasms / veterinary; Treatment Outcome
TL;DR: PHe was predictive of metastasis and OS in canine spontaneous sarcomas, the first time that pHe has been shown to be predictive of clinical outcome, and the results suggest that additional studies should be considered evaluating the prognostic significance of this variable. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2006 article

Efficacy of ronidazole for treatment of feline Tritrichomonas foetus infection

JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 20, pp. 536–543.

author keywords: colitis; diarrhea; metronidazole; nitroimidazole; tinidazole
TL;DR: Oral administration of RDZ at 30 to 50 mg/kg PO q12h for 14 days resolved diarrhea and eradicated infection in 1 naturally infected cat and 10 experimentally inoculated cats receiving a different isolate of T foetus. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2006 journal article

Correlation of brain magnetic resonance imaging changes with pallidal manganese concentrations in rhesus monkeys following subchronic manganese inhalation

TOXICOLOGICAL SCIENCES, 92(1), 219–227.

By: D. Dorman*, M. Struve, B. Wong, J. Dye & I. Robertson*

author keywords: Parkinson's disease; secondary; manganese poisoning; pharmacokinetics; inhalation exposure; Macaca mulatta; magnetic resonance imaging
MeSH headings : Animals; Globus Pallidus / anatomy & histology; Globus Pallidus / metabolism; Inhalation Exposure; Macaca mulatta; Magnetic Resonance Imaging; Manganese / metabolism; Manganese / pharmacokinetics; Manganese / toxicity
TL;DR: This first comprehensive study to use MRI, pallidal index (PI), and T(1) relaxation rate (R1) in concert with chemical analysis to establish a direct association between MRI changes and pallidal manganese concentration in rhesus monkeys following subchronic inhalation ofManganese sulfate is presented. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Bone marrow hypoplasia secondary to florfenicol toxicity in a Thomson's gazelle (Gazella thomsonii)

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 29(4), 317–319.

By: A. Tuttle n, M. Papich n & B. Wolfe n

MeSH headings : Abscess / drug therapy; Abscess / veterinary; Animals; Animals, Zoo; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / adverse effects; Blood Platelet Disorders / chemically induced; Blood Platelet Disorders / veterinary; Diagnosis, Differential; Injections, Subcutaneous / veterinary; Male; Mandibular Diseases / drug therapy; Mandibular Diseases / veterinary; Ruminants; Thiamphenicol / administration & dosage; Thiamphenicol / adverse effects; Thiamphenicol / analogs & derivatives
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2006 journal article

Nkx3.1 binds and negatively regulates the transcriptional activity of Sp-family members in prostate-derived cells

BIOCHEMICAL JOURNAL, 393, 397–409.

By: S. Simmons n & J. Horowitz n

author keywords: histone deacetylase; Nkx3.1; prostate; prostate-specific antigen; Sp protein; transrepression
MeSH headings : Animals; Cell Line; Down-Regulation; Homeodomain Proteins / genetics; Homeodomain Proteins / metabolism; Humans; Male; Mice; Promoter Regions, Genetic; Prostate / cytology; Prostate-Specific Antigen / metabolism; Sp Transcription Factors / genetics; Sp Transcription Factors / metabolism; Transcription Factors / genetics; Transcription Factors / metabolism; Transcription, Genetic; Transcriptional Activation
TL;DR: It is reported that Nkx3.1 collaborates with Sp-family members in the regulation of PSA (prostate-specific antigen) in prostate-derived cells and negatively regulates Sp-mediated transcription via the tethering of histone deacetylases and/or by inhibiting the association of Sp proteins with co-activators. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Dynamic gene expression changes precede dioxin-induced liver pathogenesis in medaka fish

TOXICOLOGICAL SCIENCES, 89(2), 524–534.

By: D. Volz, D. Hinton, J. Law* & S. Kullman

author keywords: medaka; dioxin; liver; aryl hydrocarbon receptor; gene expression; transcription
MeSH headings : Animals; Cytochrome P-450 CYP1A1 / genetics; Cytochrome P-450 CYP1A2 / genetics; Dose-Response Relationship, Drug; Gene Expression / drug effects; Gene Expression Profiling; Injections, Intraperitoneal; Liver / drug effects; Liver / metabolism; Liver / pathology; Male; Oligonucleotide Array Sequence Analysis; Oryzias; Polychlorinated Dibenzodioxins / toxicity; Receptors, Aryl Hydrocarbon / genetics; Reverse Transcriptase Polymerase Chain Reaction; Time Factors
TL;DR: The data suggest that the cellular response to dioxin involves both AHRE- and non-AHRE-mediated transcription, and that coupling gene expression profiling with analysis of morphologic pathogenesis is essential for establishing temporal relationships between transcriptional changes, toxicity, and adaptation to hepatic injury. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Methylation of tRNAAsp by the DNA Methyltransferase Homolog Dnmt2

Science, 311(5759), 395–398.

By: M. Goll n, F. Kirpekar n, K. Maggert n, J. Yoder n, C. Hsieh n, X. Zhang n, K. Golic n, S. Jacobsen n, T. Bestor n

MeSH headings : Animals; Anticodon; Arabidopsis / genetics; Arabidopsis / physiology; Arabidopsis Proteins / genetics; Catalytic Domain; Cytosine / metabolism; DNA (Cytosine-5-)-Methyltransferases / chemistry; DNA (Cytosine-5-)-Methyltransferases / genetics; DNA (Cytosine-5-)-Methyltransferases / metabolism; Drosophila Proteins / genetics; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Evolution, Molecular; Humans; Mass Spectrometry; Methylation; Mice; Mutation; NIH 3T3 Cells; RNA, Plant / metabolism; RNA, Transfer, Asp / chemistry; RNA, Transfer, Asp / metabolism; Transfection
TL;DR: The sequence and the structure of DNA methyltransferase-2 (DnMT2) bear close affinities to authentic DNA cytosine methyltransferases, and human DNMT2 protein restored methylation in vitro to tRNAAsp from Dnmt2-deficient strains of mouse, Arabidopsis thaliana, and Drosophila melanogaster in a manner that was dependent on preexisting patterns of modified nucleosides. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2006 personal communication

The dog as a cancer model

Khanna, C., Lindblad-Toh, K., Vail, D., London, C., Bergman, P., Barber, L., … Withrow, S. (2006, September).

By: C. Khanna*, K. Lindblad-Toh*, D. Vail*, C. London*, P. Bergman*, L. Barber*, M. Breen n, B. Kitchell* ...

MeSH headings : Animals; Disease Models, Animal; Dogs; Humans; Neoplasms / physiopathology; Neoplasms / veterinary
TL;DR: Rather than arguing for the importance of long-term database funding by granting agencies, BIND’s saga in fact argues for greater caution and more demanding oversight when these agencies elect to fund a database‘s initial development. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Pulmonary lesions in cats with diabetes mellitus

JOURNAL OF VETERINARY INTERNAL MEDICINE, 20(1), 47–51.

author keywords: complications of diabetes mellitus; feline; lung histopathology
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Physiological role of adrenal deoxycorticosterone-derived neuroactive steroids in stress-sensitive conditions

NEUROSCIENCE, 138(3), 911–920.

By: D. Reddy n

author keywords: allopregnanolone; anxiety; deoxycorticosterone; depression; epilepsy; GABA(A) receptor
MeSH headings : Adrenal Cortex / physiology; Adrenal Cortex / physiopathology; Animals; Desoxycorticosterone / metabolism; Disease Models, Animal; Epilepsy / physiopathology; Humans; Models, Neurological; Receptors, GABA-A / physiology; Seizures / physiopathology; Steroids / physiology; Stress, Physiological / physiopathology
TL;DR: These studies indicate that the anticonvulsant activity of deoxycorticosterone is mediated by its conversion to allotetrahydrodeoxycORTicosterone, which is a potent positive allosteric modulator of GABA(A) receptors. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2006 journal article

NF-kappa B-mediated expression of iNOS promotes epithelial defense against infection by Cryptosporidium parvum in neonatal piglets

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 290(1), G164–G174.

By: J. Gookin*, S. Chiang*, J. Allen*, M. Armstrong*, S. Stauffer*, C. Finnegan, M. Murtaugh

author keywords: nitric oxide; barrier function; diarrhea; cryptosporidiosis
MeSH headings : Animals; Animals, Newborn; Body Weight; Chlorides / metabolism; Cryptosporidiosis / enzymology; Cryptosporidiosis / metabolism; Cryptosporidium parvum / immunology; Epithelial Cells / metabolism; Gene Expression Regulation, Enzymologic; Ileum / cytology; Ileum / metabolism; Ileum / ultrastructure; Intestinal Mucosa / cytology; Intestinal Mucosa / metabolism; Intestinal Mucosa / pathology; NF-kappa B / metabolism; Nitric Oxide Synthase Type II / genetics; Nitric Oxide Synthase Type II / metabolism; Swine; Swine Diseases / enzymology; Swine Diseases / metabolism; Swine Diseases / parasitology
TL;DR: It is shown that mucosal expression of inducible nitric oxide (NO) synthase (iNOS) is increased in infected piglets and that inhibition of iNOS in vitro has no short-term effect on barrier function, suggesting that induction of i NOS represents a nonspecific response of the epithelium that mediates enterocyte defense against C. parvum infection. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2006 review

Infections of the head and ocular structures in the horse

[Review of ]. VETERINARY CLINICS OF NORTH AMERICA-EQUINE PRACTICE, 22(2), 591-+.

By: M. Gerard*, K. Wotman & A. Komaromy

MeSH headings : Animals; Anti-Infective Agents / therapeutic use; Antifungal Agents / therapeutic use; Antiviral Agents / therapeutic use; Empyema / diagnosis; Empyema / therapy; Empyema / veterinary; Eye Infections / diagnosis; Eye Infections / therapy; Eye Infections / veterinary; Horse Diseases / diagnosis; Horse Diseases / microbiology; Horse Diseases / therapy; Horses; Mycoses / diagnosis; Mycoses / therapy; Mycoses / veterinary; Periodontal Diseases / diagnosis; Periodontal Diseases / therapy; Periodontal Diseases / veterinary; Recurrence; Respiratory Tract Infections / diagnosis; Respiratory Tract Infections / therapy; Respiratory Tract Infections / veterinary; Sinusitis / diagnosis; Sinusitis / microbiology; Sinusitis / therapy; Sinusitis / veterinary; Uveitis / diagnosis; Uveitis / therapy; Uveitis / veterinary
TL;DR: This article focuses on bacterial and fungal infections of the main anatomic regions of the equine head, where advances in diagnosis and management have been made or consolidated in recent years, and addresses recent advances made in the area of infectious equine corneal disease. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Evaluation of an implanted osmotic pump for delivery of amikacin to corn snakes (Elaphe guttata guttata)

JOURNAL OF ZOO AND WILDLIFE MEDICINE, 37(3), 373–380.

By: J. Sykes*, E. Ramsay, J. Schumacher, G. Daniel, S. Cox & M. Papich*

author keywords: alzet((R)) osmotic pump; amikacin; renal scintigraphy; hypercalcemia; hyperphosphatemia; pharmacokinetics; Elaphe guttata; snake
MeSH headings : Amikacin / administration & dosage; Amikacin / blood; Amikacin / pharmacokinetics; Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Area Under Curve; Drug Administration Routes / veterinary; Drug Delivery Systems / methods; Drug Delivery Systems / veterinary; Female; Infusion Pumps, Implantable / veterinary; Injections, Intramuscular / veterinary; Kidney / diagnostic imaging; Kidney / metabolism; Kidney / physiology; Male; Predictive Value of Tests; Radionuclide Imaging; Snakes / blood; Snakes / metabolism
TL;DR: Osmotic pumps loaded with amikacin were surgically placed into the coelomic cavity of five adult corn snakes and were efficacious in achieving a constant plasma concentration of amikACin at the predicted level. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2006 article

Errors in development of fetuses and placentas from in vitro-produced bovine embryos

Farin, P. W., Piedrahita, J. A., & Farin, C. E. (2006, January 7). THERIOGENOLOGY, Vol. 65, pp. 178–191.

author keywords: bovine; embryo culture; nuclear transfer; fetus; placenta
MeSH headings : Animals; Breeding / methods; Cattle / embryology; Embryo Culture Techniques / methods; Embryo Culture Techniques / veterinary; Embryo Transfer / veterinary; Embryonic Development; Female; Fertilization in Vitro / veterinary; Gene Expression Regulation, Developmental; Male; Nuclear Transfer Techniques; Phenotype; Placenta / blood supply; Placenta / physiology; Placentation; Pregnancy; Pregnancy Complications / epidemiology; Pregnancy Complications / veterinary; Pregnancy Outcome / veterinary
TL;DR: The term 'abnormal offspring syndrome (AOS)' is introduced and a classification system of developmental outcomes is proposed to facilitate research efforts on the mechanisms of the various abnormal phenotypes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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