Works Published in 2013

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Displaying works 81 - 100 of 127 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2013 journal article

Doxycycline concentration over time after storage in a compounded veterinary preparation

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 242(12), 1674–1678.

By: M. Papich*, G. Davidson & L. Fortier

MeSH headings : Anti-Bacterial Agents / chemistry; Chemistry, Pharmaceutical; Doxycycline / chemistry; Drug Compounding; Drug Stability; Drug Storage; Suspensions; Time Factors; Veterinary Drugs / chemistry
TL;DR: The concentration of doxycycline compounded from commercial tablets in the vehicles evaluated to yield doses of 33.3 and 166.7 mg/mL cannot be assured beyond 7 days, and the quality of the formulations decreased as well. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2013 journal article

Conditioning laboratory cats to handling and transport

LAB ANIMAL, 42(10), 385–389.

By: M. Gruen n, A. Thomson n, G. Clary*, A. Hamilton n, L. Hudson n, R. Meeker*, B. Sherman n

MeSH headings : Animal Husbandry / methods; Animal Welfare; Animals; Cats / physiology; Conditioning, Classical; Handling, Psychological; Housing, Animal; Stress, Physiological; Time Factors; Transportation
TL;DR: A behavioral protocol used in their laboratory to condition cats to condition them to handling and transport benefits the welfare of the cats, the safety of animal technicians and the quality of feline research data. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Assessment of geographical variation in the respiratory toxicity of desert dust particles

INHALATION TOXICOLOGY, 25(7), 405–416.

By: K. Taylor n, M. Foster n, J. Law n, J. Centeno*, E. Fornero*, M. Henderson n, S. Trager n, M. Stockelman*, D. Dorman n

author keywords: Cytotoxicity; dust inhalation; in vitro; in vivo; particle toxicity; pulmonary toxicity; rat
MeSH headings : Administration, Inhalation; Afghanistan; Animals; Arsenic / analysis; Arsenic / toxicity; Bronchoalveolar Lavage Fluid / chemistry; Bronchoalveolar Lavage Fluid / cytology; Cell Count; Cell Line; Cell Survival / drug effects; Cytokines / metabolism; Dust / analysis; Endotoxins / analysis; Endotoxins / toxicity; Geography; Iraq; L-Lactate Dehydrogenase / metabolism; Lung / drug effects; Lung / metabolism; Lung / pathology; Male; Metals / analysis; Metals / toxicity; Rats; Silicon Dioxide / analysis; Silicon Dioxide / toxicity; United States
TL;DR: The in vitro cytotoxicity assay results were partially predictive of in vivo responses and could be used to prioritize future particle inhalation studies or guide epidemiological study design. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Antimicrobials, Susceptibility Testing, and Minimum Inhibitory Concentrations (MIC) in Veterinary Infection Treatment

Veterinary Clinics of North America: Small Animal Practice, 43(5), 1079–1089.

By: M. Papich n

author keywords: Antimicrobials; Minimum inhibitory concentration; Susceptibility testing; Veterinary infection treatment
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / therapeutic use; Bacteria / drug effects; Bacterial Infections / drug therapy; Bacterial Infections / microbiology; Bacterial Infections / veterinary; Bacteriological Techniques; Dogs; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Veterinary Drugs
TL;DR: There are many reasons why antimicrobial treatment fails and when evaluating a patient that has failed to respond to therapy, one must consider any of the many factors that contribute to antibiotic failure. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2013 journal article

Antibiotic Treatment of Resistant Infections in Small Animals

Veterinary Clinics of North America: Small Animal Practice, 43(5), 1091–1107.

By: M. Papich n

author keywords: Antibiotics; Resistance; Infection; Small animals
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / therapeutic use; Bacterial Infections / drug therapy; Bacterial Infections / microbiology; Bacterial Infections / veterinary; Cat Diseases / drug therapy; Cat Diseases / microbiology; Cats; Dog Diseases / drug therapy; Dog Diseases / microbiology; Dogs; Drug Resistance, Bacterial
TL;DR: There are few veterinary clinical studies to support a recommended use and dose for treating resistant bacterial infections in small animals and a susceptibility test is needed to identify the appropriate drug for these infections. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2013 journal article

The pharmacokinetics of midazolam after intravenous, intramuscular, and rectal administration in healthy dogs

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 36(5), 471–477.

MeSH headings : Administration, Rectal; Animals; Anticonvulsants / administration & dosage; Anticonvulsants / blood; Anticonvulsants / pharmacokinetics; Chromatography, High Pressure Liquid; Dogs; Female; Injections, Intramuscular / veterinary; Injections, Intravenous / veterinary; Male; Midazolam / administration & dosage; Midazolam / blood; Midazolam / pharmacokinetics
TL;DR: It is suggested that IM midazolam might be useful in treating seizures in dogs when venous access is unavailable, but higher doses may be needed to account for intermediate bioavailability. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2013 journal article

Suspected carprofen toxicosis caused by coprophagia in a dog

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 243(5), 709–711.

MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / adverse effects; Carbazoles / adverse effects; Coprophagia; Dog Diseases / chemically induced; Dogs; Female
TL;DR: Findings for the dog of this report suggested that carprofen toxicosis can be caused by consumption of feces of another dog receiving the drug. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Quantifiable Long-term Monitoring on Parks and Nature Preserves

SOUTHEASTERN NATURALIST, 12(2), 339–352.

By: S. Becker, C. Moorman*, C. DePerno* & T. Simons*

TL;DR: A case study at Hemlock Bluffs Nature Preserve in Cary, NC to model occupancy of focal species and demonstrate a replicable long-term protocol useful to parks and nature preserves with limited resources. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Pharmacodynamics of Doxycycline and Tetracycline against Staphylococcus pseudintermedius: Proposal of Canine-Specific Breakpoints for Doxycycline

JOURNAL OF CLINICAL MICROBIOLOGY, 51(11), 3547–3554.

By: M. Maaland*, M. Papich n, J. Turnidge* & L. Guardabassi*

MeSH headings : Animals; Anti-Bacterial Agents / pharmacokinetics; Anti-Bacterial Agents / pharmacology; Dog Diseases / drug therapy; Dog Diseases / microbiology; Dogs; Doxycycline / pharmacokinetics; Doxycycline / pharmacology; Microbial Sensitivity Tests; Models, Theoretical; Staphylococcal Infections / drug therapy; Staphylococcal Infections / microbiology; Staphylococcal Infections / veterinary; Staphylococcus / drug effects; Tetracycline / pharmacokinetics; Tetracycline / pharmacology
TL;DR: Doxycycline was more active than tetracycline in non-wild-type strains and the two drugs displayed bacteriostatic activity and bimodal MIC distributions, and canine-specific doxycycline MIC breakpoints were proposed based on the data generated in this study. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2013 journal article

Partial cytogenetic response with toceranib and prednisone treatment in a young dog with chronic monocytic leukemia

ANTI-CANCER DRUGS, 24(10), 1098–1103.

By: M. Perez, S. Culver*, J. Owen*, M. Dunbar*, K. Kow, M. Breen n, R. Milner*

author keywords: cytogenetic analysis; fluorescence in-situ hybridization; monocytosis; toceranib; tyrosine kinase inhibitor
MeSH headings : Animals; Antineoplastic Combined Chemotherapy Protocols / administration & dosage; Antineoplastic Combined Chemotherapy Protocols / therapeutic use; Cell Proliferation / drug effects; Dog Diseases / drug therapy; Dog Diseases / genetics; Dogs; Female; Fusion Proteins, bcr-abl / antagonists & inhibitors; Fusion Proteins, bcr-abl / genetics; In Situ Hybridization, Fluorescence; Indoles / administration & dosage; Indoles / therapeutic use; Leukemia, Myeloid / drug therapy; Leukemia, Myeloid / genetics; Leukemia, Myeloid / pathology; Leukemia, Myeloid / veterinary; Prednisone / administration & dosage; Prednisone / therapeutic use; Pyrroles / administration & dosage; Pyrroles / therapeutic use; Translocation, Genetic; Treatment Outcome
TL;DR: A case of CMoL in a young dog that achieved clinical remission with treatment with the tyrosine kinase inhibitor toceranib and prednisone is reported. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Mortality in Kittens Is Associated with a Shift in Ileum Mucosa-Associated Enterococci from Enterococcus hirae to Biofilm-Forming Enterococcus faecalis and Adherent Escherichia coli

JOURNAL OF CLINICAL MICROBIOLOGY, 51(11), 3567–3578.

By: A. Ghosh*, L. Borst n, S. Stauffer n, M. Suyemoto n, P. Moisan*, L. Zurek*, J. Gookin n

MeSH headings : Animals; Animals, Newborn; Biofilms / growth & development; Biota; Cat Diseases / microbiology; Cat Diseases / mortality; Cats; Enteritis / microbiology; Enteritis / mortality; Enteritis / veterinary; Enterococcus / isolation & purification; Enterococcus / physiology; Escherichia coli / isolation & purification; Escherichia coli / physiology; Ileum / microbiology; Intestinal Mucosa / microbiology
TL;DR: A significant difference is identified in the species of enterococci cultured from the ileum mucosa of kittens with terminal illness compared to the species cultured from healthy kittens, which is identified as more common and extensive in healthy kittens than in sick kittens. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2013 journal article

Molecular characterization of canine BCR-ABL-positive chronic myelomonocytic leukemia before and after chemotherapy

VETERINARY CLINICAL PATHOLOGY, 42(3), 314–322.

By: S. Culver n, D. Ito*, L. Borst n, J. Bell, J. Modiano* & M. Breen n

author keywords: Chromosome; cytogenetics; hematopoietic cells; remission; vincristine
MeSH headings : Animals; Chromosomes, Human, Pair 7 / genetics; Comparative Genomic Hybridization / veterinary; Dog Diseases / drug therapy; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Fusion Proteins, bcr-abl / genetics; Humans; In Situ Hybridization, Fluorescence / veterinary; Leukemia, Myelomonocytic, Chronic / drug therapy; Leukemia, Myelomonocytic, Chronic / genetics; Leukemia, Myelomonocytic, Chronic / pathology; Leukemia, Myelomonocytic, Chronic / veterinary; Male; Trisomy / genetics
TL;DR: Cytology and flow cytometric techniques were used to diagnose chronic myelomonocytic leukemia in a dog and the applicability of cytogenetics techniques to evaluate the cytogenetic response of canine leukemia to chemotherapy was demonstrated. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Assessment of Plasma Concentrations and Potential Adverse Effects of Doxycycline in Cockatiels (Nymphicus hollandicus) Fed a Medicated Pelleted Diet

JOURNAL OF AVIAN MEDICINE AND SURGERY, 27(3), 187–193.

By: K. Flammer n, J. Massey n, T. Roudybush, C. Meek n & M. Papich n

author keywords: Chlamydophila psittaci; spiral bacteria; antimicrobial drug; doxycycline; pharmacology; avian; cockatiel; Nymphicus hollandicus
MeSH headings : Animal Feed / analysis; Animals; Anti-Bacterial Agents / adverse effects; Anti-Bacterial Agents / blood; Cockatoos / blood; Doxycycline / adverse effects; Doxycycline / blood; Food Handling; Time Factors
TL;DR: This medicated diet may be suitable for treating spiral bacteria and Chlamydophila psittaci infections in cockatiels that will consume a pelleted diet. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2013 journal article

Sphingosine-1-phosphate exhibits anti-proliferative and anti-inflammatory effects in mouse models of psoriasis

JOURNAL OF DERMATOLOGICAL SCIENCE, 71(1), 29–36.

By: K. Schaper, J. Dickhaut, L. Japtok, M. Kietzmann, R. Mischke, B. Kleuser, W. Baeumer

author keywords: Imiquimod; Psoriasis; SCID mice; Sphingosine-1-phosphate
MeSH headings : Administration, Cutaneous; Aminoquinolines; Animals; Anti-Inflammatory Agents / administration & dosage; Anti-Inflammatory Agents / pharmacology; Betamethasone / analogs & derivatives; Betamethasone / pharmacology; Calcitriol / analogs & derivatives; Calcitriol / pharmacology; Cell Differentiation / drug effects; Cell Proliferation / drug effects; Dermatologic Agents / administration & dosage; Dermatologic Agents / pharmacology; Disease Models, Animal; Female; Fingolimod Hydrochloride; Humans; Imiquimod; Keratinocytes / drug effects; Keratinocytes / metabolism; Keratinocytes / pathology; Local Lymph Node Assay; Lysophospholipids / administration & dosage; Lysophospholipids / pharmacology; Mice; Mice, Inbred BALB C; Mice, SCID; Propylene Glycols / administration & dosage; Propylene Glycols / pharmacology; Psoriasis / chemically induced; Psoriasis / drug therapy; Psoriasis / metabolism; Psoriasis / pathology; Receptors, Lysosphingolipid / drug effects; Receptors, Lysosphingolipid / metabolism; Skin / drug effects; Skin / metabolism; Skin / pathology; Skin Transplantation; Sphingosine / administration & dosage; Sphingosine / analogs & derivatives; Sphingosine / pharmacology; Sphingosine-1-Phosphate Receptors; Time Factors
TL;DR: Results imply that topical administration of S1P might be a new option for the treatment of mild to moderate psoriasis lesions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Identification of neuronal loci involved with displays of affective aggression in NC900 mice

BRAIN STRUCTURE & FUNCTION, 218(4), 1033–1049.

By: D. Nehrenberg n, A. Sheikh n & H. Ghashghaei n

author keywords: Aggression; Violence; Neuronal circuits; Neural networks; Neuronal activity; Amygdala; Nucleus accumbens; Hypothalamus; Limbic thalamus; Parafascicular thalamic nucleus; Paraventricular thalamic nucleus; Zona incerta; Anxiety disorders; Mouse; c-Fos
MeSH headings : Aggression / physiology; Analysis of Variance; Animals; Brain Mapping; Cell Count; Immunohistochemistry; Male; Mice; Mice, Inbred Strains; Microscopy, Confocal; Neural Pathways / physiology; Neurons / metabolism; Prosencephalon / cytology; Prosencephalon / physiology; Proto-Oncogene Proteins c-fos / metabolism
TL;DR: A detailed anatomical map of neuronal activity in the forebrain of two inbred lines of mice selected for low (NC100) and high (NC900) affective aggression is provided to speculate that neuronal activities in analogous networks may be disrupted in humans prone to maladaptive affectsive aggression. (via Semantic Scholar)
UN Sustainable Development Goal Categories
16. Peace, Justice and Strong Institutions (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Fibroblast Migration Is Regulated by Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS) Protein

PLOS ONE, 8(6).

By: L. Ott n, E. Sung n, A. Melvin n, M. Sheats n, J. Haugh n, K. Adler n, S. Jones n

MeSH headings : 3T3 Cells; Animals; Becaplermin; Chemotaxis / drug effects; Chemotaxis / physiology; Collagen / metabolism; Fibroblasts / cytology; Fibronectins / metabolism; Intracellular Signaling Peptides and Proteins / metabolism; Intracellular Signaling Peptides and Proteins / physiology; Membrane Proteins / metabolism; Membrane Proteins / physiology; Mice; Myristoylated Alanine-Rich C Kinase Substrate; Phosphorylation; Proto-Oncogene Proteins c-akt / metabolism; Proto-Oncogene Proteins c-sis / pharmacology
TL;DR: Genetic structure-function analysis revealed that MANS peptide-mediated attenuation of NIH-3T3 cell migration does not require the presence of the myristic acid moiety on the amino-terminus, and suggests that MARCKS-mediated regulation of fibroblast migration involves the MARC KS amino- terminus. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Evaluation of 3-methylhistidine levels in dogs with chronic mitral valve disease

Veterinary Record, 172(16), 426-.

By: S. Lee & C. Hyun

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Cell lineage identification and stem cell culture in a porcine model for the study of intestinal epithelial regeneration

PLoS One, 8(6).

By: L. Gonzalez, I. Williamson, J. Piedrahita, A. Blikslager & S. Magness

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Assessment of a novel group-centered testing schema in an upper-level undergraduate molecular biotechnology course

BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION, 41(4), 232–241.

By: M. Srougi n, H. Miller*, D. Witherow* & S. Carson n

author keywords: biotechnology; problem-based testing; collaborative learning; undergraduate
MeSH headings : Biotechnology / education; Curriculum; Educational Measurement / methods; Faculty; Humans; Learning; Students
TL;DR: It is suggested that group‐centered, problem‐based learning is a useful model for achievement of student learning outcomes in courses where it would be infeasible to provide feedback on individual critical thinking assignments due to grading volume. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2013 journal article

A Semantic Model for Species Description Applied to the Ensign Wasps (Hymenoptera: Evaniidae) of New Caledonia

SYSTEMATIC BIOLOGY, 62(5), 639–659.

By: J. Balhoff n, I. Miko n, M. Yoder n, P. Mullins n & A. Deans n

author keywords: Biodiversity informatics; Evaniidae; New Caledonia; new species; ontology; semantic phenotypes; semantic species description; taxonomy
MeSH headings : Animals; Classification / methods; Models, Biological; New Caledonia; Semantics; Species Specificity; Wasps / anatomy & histology; Wasps / classification
TL;DR: A revision of the ensign wasp (Hymenoptera: Evaniidae) fauna of New Caledonia is presented using this new model for species description, and a foundation to discuss limitations and potential benefits such as automated data integration and reasoner-driven queries is provided. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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