Works Published in 2014
Displaying works 81 - 100 of 135 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2014 journal article
Virtual Microscopy: A Useful Tool for Meeting Evolving Challenges in the Veterinary Medical Curriculum
JOURNAL OF SCIENCE EDUCATION AND TECHNOLOGY, 23(6), 756–762.
author keywords: Online; Virtual; Microscopy; Histology; Veterinary education; Doctor of Veterinary Medicine curriculum
TL;DR:
Results of a survey given to assess Professional Veterinary Medical students’ perceptions of using virtual microscope for learning basic histology/microscopic anatomy are discussed and implications of these results for using virtual microscopy as a pedagogical tool in teaching first-year Professional Veterinary medicalStudents’ basic histological concepts are discussed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Surgical treatment of synovial osteochondromatosis in the middle carpal joint of a pony
EQUINE VETERINARY EDUCATION, 26(8), 395–399.
author keywords: horse; synovial osteochondromatosis; arthroscopic; carpus
TL;DR:
Radiographic, ultrasonographic and arthroscopic evaluation of the left carpus was consistent with synovial osteochondromatosis, and this presumptive clinical diagnosis was confirmed histopathologically.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Genomic profiling reveals extensive heterogeneity in somatic DNA copy number aberrations of canine hemangiosarcoma
CHROMOSOME RESEARCH, 22(3), 305–319.
author keywords: canine; chromosome; hemangiosarcoma; comparative genomic hybridization (CGH)
MeSH headings : Animals; Breeding; Comparative Genomic Hybridization; DNA Copy Number Variations / genetics; Dog Diseases / genetics; Dogs; Gene Amplification; Gene Expression Profiling; Genetic Heterogeneity; Genome; Hemangiosarcoma / genetics; Hemangiosarcoma / veterinary; Penetrance; Vascular Endothelial Growth Factor A / genetics
TL;DR:
Analysis of genome-wide microarray-based somatic DNA copy number profiling of 75 primary intra-abdominal hemangiosarcomas from five popular dog breeds supports prior transcriptional studies suggesting that the clinical heterogeneity of this cancer may reflect the existence of multiple, molecularly distinct subtypes of canine hemangiusarcoma.
(via Semantic Scholar)
europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Prostatitis, Steatitis, and Diarrhea in a Dog following Presumptive Flea-Borne Transmission of Bartonella henselae
JOURNAL OF CLINICAL MICROBIOLOGY, 52(9), 3447–3452.
MeSH headings : Animals; Bartonella Infections / complications; Bartonella Infections / microbiology; Bartonella Infections / pathology; Bartonella Infections / veterinary; Bartonella henselae / isolation & purification; Diarrhea / microbiology; Diarrhea / pathology; Diarrhea / veterinary; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Flea Infestations / complications; Flea Infestations / veterinary; Male; Prostatitis / diagnosis; Prostatitis / microbiology; Prostatitis / pathology; Steatitis / microbiology; Steatitis / pathology
TL;DR:
A dog developed an unusual clinical presentation for canine bartonellosis following an acute flea infestation, and comprehensive medical, microbiological, and surgical interventions were required for diagnosis and to achieve a full recovery.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Myristoylated Alanine Rich C Kinase Substrate (MARCKS) is essential to beta 2-integrin dependent responses of equine neutrophils
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 160(3-4), 167–176.
author keywords: Neutrophil; Migration; Adhesion; Respiratory burst; Beta2-integrin; Inflammation
MeSH headings : Amino Acid Sequence; Animals; Antigen-Antibody Complex / physiology; CD18 Antigens / immunology; CD18 Antigens / physiology; Cell Adhesion / drug effects; Cell Adhesion / physiology; Cell Movement / drug effects; Cell Movement / physiology; Conserved Sequence; Horses / immunology; Horses / physiology; In Vitro Techniques; Intracellular Signaling Peptides and Proteins / antagonists & inhibitors; Intracellular Signaling Peptides and Proteins / genetics; Intracellular Signaling Peptides and Proteins / physiology; Membrane Proteins / antagonists & inhibitors; Membrane Proteins / genetics; Membrane Proteins / physiology; Molecular Sequence Data; Myristoylated Alanine-Rich C Kinase Substrate; Neutrophil Infiltration / drug effects; Neutrophil Infiltration / immunology; Neutrophil Infiltration / physiology; Peptide Fragments / genetics; Peptide Fragments / pharmacology; Respiratory Burst / drug effects; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate / pharmacology
TL;DR:
It is demonstrated that inhibition of MARCKS function significantly attenuates β2-integrin-dependent neutrophil functions including migration, adhesion, and immune complex-mediated respiratory burst, and strongly implicate MARC KS as a potential regulator of β 2-integrins in neutrophils.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Hypoxia induced changes in expression of proteins involved in iron uptake and storage in cultured lens epithelial cells
EXPERIMENTAL EYE RESEARCH, 125, 135–141.
author keywords: lens; iron; iron proteins; hypoxia
MeSH headings : Animals; Cell Hypoxia / physiology; Cells, Cultured; Dogs; Epithelial Cells / metabolism; Ferritins / metabolism; Gene Expression Regulation; Lens, Crystalline / cytology; Lens, Crystalline / metabolism; Oxidative Stress / physiology; RNA, Messenger / metabolism; Real-Time Polymerase Chain Reaction; Receptors, Transferrin / metabolism; Transferrin / metabolism
TL;DR:
Changes in expression of ferritin and Tf/TfR1 in LEC cultured under hypoxic conditions are examined to better protect LEC against oxidative stress by limiting iron-catalyzed ROS formation in the low oxygen environment in which the lens resides.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Hypoxia controls iron metabolism and glutamate secretion in retinal pigmented epithelial cells
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1840(10), 3138–3144.
author keywords: Iron transport; Glutamate; Hypoxia; Blood-ocular barriers
MeSH headings : Animals; Cell Hypoxia; Cells, Cultured; Dogs; Epithelial Cells / metabolism; Epithelial Cells / pathology; Glutamic Acid / metabolism; Humans; Iron / metabolism; Oxidation-Reduction; Retinal Pigment Epithelium / metabolism; Retinal Pigment Epithelium / pathology; Stroke / metabolism; Stroke / pathology
TL;DR:
Iron, a key catalyst of free radical generation, is removed from RPE under hypoxic conditions which may help protect RPE from oxidative stress and indicate the importance of using polarized tight junctional cells as more physiologically relevant models for blood-barrier-like systems.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Evaluation of standard magnetic resonance characteristics used to differentiate neoplastic, inflammatory, and vascular brain lesions in dogs
Veterinary Radiology & Ultrasound, 55(4), 399–406.
Source: NC State University Libraries
Added: August 6, 2018
2014 journal article
COMPUTED TOMOGRAPHIC FEATURES OF CANINE NONPARENCHYMAL HEMANGIOSARCOMA
VETERINARY RADIOLOGY & ULTRASOUND, 55(4), 374–379.
author keywords: CT; Dog; Hemangiosarcoma
MeSH headings : Animals; Contrast Media; Dog Diseases / diagnostic imaging; Dog Diseases / etiology; Dog Diseases / pathology; Dogs; Female; Hemangiosarcoma / diagnostic imaging; Hemangiosarcoma / etiology; Hemangiosarcoma / pathology; Hemangiosarcoma / veterinary; Male; Retrospective Studies; Tomography, X-Ray Computed / veterinary
TL;DR:
Findings indicated that there were no unique distinguishing CT characteristics for nonparenchymal hemangiosarcoma in dogs; however, the presence of highly attenuating foci of contrast enhancement may warrant further investigation in prospective diagnostic sensitivity and treatment outcome studies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Stem Cells and Regenerative Medicine in Domestic and Companion Animals: A Multispecies Perspective
Reproduction in Domestic Animals, 49, 2–10.
MeSH headings : Adult; Animals; Animals, Domestic / embryology; Cats; Dogs; Embryonic Stem Cells; Horses; Humans; Induced Pluripotent Stem Cells; Mice; Pets / embryology; Rats; Regenerative Medicine / trends; Stem Cells
TL;DR:
A range of stem cells are reviewed, from ESC to induced pluripotent stem cells, and their potential application in the field of regenerative medicine is discussed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref
Added: August 6, 2018
2014 journal article
SnRK1 Phosphorylation of AL2 Delays Cabbage Leaf Curl Virus Infection in Arabidopsis
JOURNAL OF VIROLOGY, 88(18), 10598–10612.
MeSH headings : Amino Acid Sequence; Arabidopsis / enzymology; Arabidopsis / genetics; Arabidopsis / virology; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Begomovirus / chemistry; Begomovirus / classification; Begomovirus / genetics; Begomovirus / metabolism; Host-Pathogen Interactions; Molecular Sequence Data; Phylogeny; Plant Diseases / virology; Protein Binding; Protein Kinases / genetics; Protein Kinases / metabolism; Transcription Factors / genetics; Transcription Factors / metabolism; Viral Proteins / chemistry; Viral Proteins / genetics; Viral Proteins / metabolism
TL;DR:
It is shown that the host protein kinase SnRK1, a central regulator of energy balance and nutrient metabolism in plants, phosphorylates serine-109 in AL2 proteins of three subgroups of New World begomoviruses, resulting in a delay in viral DNA accumulation and symptom appearance.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
N-Terminal Pro-C-Natriuretic Peptide and Cytokine Kinetics in Dogs with Endotoxemia
JOURNAL OF VETERINARY INTERNAL MEDICINE, 28(5), 1447–1453.
author keywords: Biomarker; ELISA; Immunology; Inflammation; Multiplex; Sepsis
MeSH headings : Animals; Chemokine CCL2 / blood; Chemokine CXCL10 / blood; Chemokines / blood; Cross-Over Studies; Cytokines / blood; Dog Diseases / blood; Dog Diseases / metabolism; Dogs / blood; Endotoxemia / blood; Endotoxemia / metabolism; Endotoxemia / veterinary; Female; Interleukin-10 / blood; Interleukin-6 / blood; Interleukin-8 / blood; Natriuretic Peptide, C-Type / blood; Sepsis / blood; Sepsis / metabolism; Sepsis / veterinary; Tumor Necrosis Factor-alpha / blood
TL;DR:
Serum NT‐proCNP concentration does not change significantly in response to LPS administration in healthy dogs and certain serum cytokine and chemokine concentrations are significantly increased within 1–4 hours after L PS administration and warrant further investigation as tools for the detection and management of sepsis in dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Canine Prostate Cancer Cell Line (Probasco) Produces Osteoblastic Metastases In Vivo
PROSTATE, 74(13), 1251–1265.
author keywords: prostate cancer; osteoblastic metastases; canine; dog
MeSH headings : Animals; Biomarkers, Tumor / genetics; Biomarkers, Tumor / metabolism; Bone Neoplasms / genetics; Bone Neoplasms / metabolism; Bone Neoplasms / secondary; Carcinoma / genetics; Carcinoma / metabolism; Carcinoma / secondary; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dogs; Male; Mice; Mice, Nude; Neoplasm Transplantation; Osteoblasts / metabolism; Osteoblasts / pathology; Prostatic Neoplasms / genetics; Prostatic Neoplasms / metabolism; Prostatic Neoplasms / pathology
TL;DR:
This study established and characterized a novel canine prostate cancer cell line that will contribute to the understanding of prostate cancer pathogenesis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
The Effect of Tramadol and Indomethacin Coadministration on Gastric Barrier Function in Dogs
JOURNAL OF VETERINARY INTERNAL MEDICINE, 28(3), 793–798.
author keywords: NSAID; tramadol; ulcer
MeSH headings : Analgesics, Opioid / administration & dosage; Analgesics, Opioid / pharmacology; Animals; Anti-Inflammatory Agents, Non-Steroidal / administration & dosage; Anti-Inflammatory Agents, Non-Steroidal / pharmacology; Cyclooxygenase 1 / metabolism; Cyclooxygenase 2 / metabolism; Dinoprostone / analysis; Dogs; Drug Therapy, Combination; Gastric Mucosa / chemistry; Gastric Mucosa / drug effects; Gastric Mucosa / physiology; Indomethacin / administration & dosage; Indomethacin / pharmacology; Thromboxane B2 / analysis; Tramadol / administration & dosage; Tramadol / pharmacology
TL;DR:
The results suggest that if there is an adverse interaction of the 2 drugs in vivo, it is unlikely to be via prostanoid inhibition, and could be via nonselective cyclooxygenase inhibition.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
PHARMACOKINETICS OF SINGLE DOSE ORAL MELOXICAM IN BOTTLENOSE DOLPHINS (TURSIOPS TRUNCATUS)
JOURNAL OF ZOO AND WILDLIFE MEDICINE, 45(3), 594–599.
author keywords: Bottlenose dolphin; pharmacokinetics; meloxicam; Tursiops truncatus
MeSH headings : Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal / administration & dosage; Anti-Inflammatory Agents, Non-Steroidal / blood; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Bottle-Nosed Dolphin / blood; Female; Male; Meloxicam; Thiazines / administration & dosage; Thiazines / blood; Thiazines / pharmacokinetics; Thiazoles / administration & dosage; Thiazoles / blood; Thiazoles / pharmacokinetics
TL;DR:
The elimination of meloxicam in cetaceans was slower than in other species, with an elimination half-life of almost 70 hr, and detectable drug concentrations up to 7 days, suggesting that a single oral dose of 0.1 mg/kg appears safe for use in this species.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2014 journal article
Minocycline pharmacokinetics and pharmacodynamics in dogs: dosage recommendations for treatment of meticillin-resistant Staphylococcus pseudintermedius infections
Veterinary Dermatology, 25(3), 182–e47.
MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Anti-Bacterial Agents / pharmacology; Area Under Curve; Cross-Over Studies; Dog Diseases / drug therapy; Dog Diseases / microbiology; Dogs; Dose-Response Relationship, Drug; Half-Life; Methicillin Resistance; Minocycline / administration & dosage; Minocycline / blood; Minocycline / pharmacokinetics; Minocycline / pharmacology; Staphylococcal Skin Infections / drug therapy; Staphylococcal Skin Infections / veterinary; Staphylococcus / drug effects; Tissue Distribution
TL;DR:
This study provides dosage recommendations for therapy of meticillin-resistant Staphylococcus pseudintermedius infections in dogs and provides PK/PD data necessary to consider species-specific clinical breakpoints for minocycline susceptibility testing.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018
2014 journal article
Magnetic targeting of cardiosphere-derived stem cells with ferumoxytol nanoparticles for treating rats with myocardial infarction
BIOMATERIALS, 35(30), 8528–8539.
author keywords: Cardiac stem cells; Magnetic targeting; Myocardial infarction; Ferumoxytol; MRI; Superparamagnetic iron oxide nanoparticles
MeSH headings : Animals; Apoptosis / drug effects; Cell Movement / drug effects; Cell Proliferation / drug effects; Cell Survival / drug effects; Female; Ferrosoferric Oxide / pharmacology; Ferrosoferric Oxide / therapeutic use; Finite Element Analysis; Heart Function Tests; Heparin / pharmacology; Humans; Inflammation / pathology; Iron Overload / pathology; Magnetic Phenomena; Male; Myocardial Infarction / pathology; Myocardial Infarction / physiopathology; Myocardial Infarction / therapy; Myocardium / pathology; Nanoparticles / therapeutic use; Nanoparticles / ultrastructure; Neovascularization, Physiologic / drug effects; Protamines / pharmacology; Rats; Rats, Inbred WKY; Spheroids, Cellular / drug effects; Spheroids, Cellular / pathology
TL;DR:
FHP labeling is safe to cardiac stem cells and facilitates magnetically-targeted stem cell delivery into the heart which leads to augmented cell engraftment and therapeutic benefit, and magnetic targeting increased cardiac retention of transplanted FHP-rCDCs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Magnetic antibody-linked nanomatchmakers for therapeutic cell targeting
Nature Communications, 5(1).
MeSH headings : Animals; Antibodies; Bone Marrow Cells / metabolism; Bone Marrow Transplantation / methods; Cell Movement; Ferrosoferric Oxide / therapeutic use; Iron; Leukocytes, Mononuclear / metabolism; Magnets; Myocardial Infarction / therapy; Myocytes, Cardiac / metabolism; Nanotechnology / methods; Rats; Regeneration; Stem Cells
TL;DR:
The authors use magnetic iron nanoparticles conjugated with antibodies that bind therapeutic cells and cardiomyocytes to treat myocardial ischemia/reperfusion injury in rats and show that targeting to the heart is enhanced upon local application of a magnetic field.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, Crossref
Added: August 6, 2018
2014 journal article
A novel canine model of immune thrombocytopenia: has immune thrombocytopenia (ITP) gone to the dogs?
BRITISH JOURNAL OF HAEMATOLOGY, 167(1), 110–120.
author keywords: immune thrombocytopenia; canine; interleukin-8; animal model
MeSH headings : Animals; Antibodies, Monoclonal / administration & dosage; Antibodies, Monoclonal / adverse effects; Antibodies, Monoclonal / immunology; Blood Platelets / immunology; Blood Platelets / metabolism; Cytokines / blood; Cytokines / metabolism; Disease Models, Animal; Dogs; Hemorrhage / immunology; Phenotype; Platelet Count; Purpura, Thrombocytopenic, Idiopathic / blood; Purpura, Thrombocytopenic, Idiopathic / diagnosis; Purpura, Thrombocytopenic, Idiopathic / immunology
TL;DR:
Evaluation of cytokine profiles led to the identification of platelets as a potential source of serum interleukin‐8 (IL8) in dogs, suggesting that platelet IL8 may be a previously unrecognized modulator of platelet‐neutrophil crosstalk in humans with ITP.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Whole-Genome Analysis of Temporal Gene Expression during Early Transdifferentiation of Human Lung Alveolar Epithelial Type 2 Cells In Vitro
PLOS ONE, 9(4).
MeSH headings : Alveolar Epithelial Cells / cytology; Alveolar Epithelial Cells / metabolism; Caveolin 1 / genetics; Caveolin 1 / metabolism; Cell Transdifferentiation / genetics; Cells, Cultured; Gene Expression; Gene Expression Profiling; Gene Expression Regulation; Genome-Wide Association Study; Humans; Protein Transport; Reproducibility of Results; Time Factors; Transcriptome
TL;DR:
The utility of genome-wide analysis to identify relevant, novel cell type-specific signatures of early ECM-regulated alveolar epithelial transdifferentiation processes in vitro is demonstrated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.
Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.