Works Published in 2020
Displaying works 141 - 160 of 216 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2020 journal article
Viscoelastic Response Ultrasound Derived Relative Elasticity and Relative Viscosity Reflect True Elasticity and Viscosity: In Silico and Experimental Demonstration
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 67(6), 1102–1117.
author keywords: Acoustic radiation force impulse (ARFI); mass-spring-damper (MSD); shear wave dispersion ultrasound vibrometry (SDUV); shear wave elasticity; ultrasound; viscoelastic response (VisR) ultrasound; viscoelasticity
MeSH headings : Animals; Computer Simulation; Dogs; Elasticity / physiology; Elasticity Imaging Techniques / methods; Image Processing, Computer-Assisted / methods; Liver / diagnostic imaging; Liver / physiology; Phantoms, Imaging; Viscosity
TL;DR:
The hypothesis that RE and RV linearly correlate to true elasticity and viscosity in tissue is tested and results suggest thatRE and RV are relevant for qualitatively assessing the elastic and viscous properties of tissue.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 22, 2020
2020 journal article
Muscle activation pattern elicited through transcutaneous stimulation near the cervical spinal cord
JOURNAL OF NEURAL ENGINEERING, 17(1).
author keywords: transcutaneous electrical stimulation; spinal cord; hand function; arm function; muscle activation
MeSH headings : Adult; Arm / innervation; Arm / physiology; Cervical Cord / physiology; Electromyography / methods; Humans; Male; Muscle Contraction / physiology; Muscle, Skeletal / innervation; Muscle, Skeletal / physiology; Transcutaneous Electric Nerve Stimulation / methods; Young Adult
TL;DR:
The tsCSC approach can improve the muscle activation pattern during electrical stimulation with a possible involvement of the spinal and supraspinal pathways, which can facilitate applications on rehabilitation/assistance of individuals with impaired motor function.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Web Of Science
Added: June 22, 2020
2020 journal article
Perspectives on high resolution microvascular imaging with contrast ultrasound
APPLIED PHYSICS LETTERS, 116(21).
TL;DR:
This Perspective article introduces microvascular imaging strategies and their underlying technology and demonstrates a potential to visualize small blood vessels in vivo, unlike anything possible with traditional grayscale ultrasound.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 22, 2020
2020 journal article
Fast Automated Approach for the Derivation of Acellular Extracellular Matrix Scaffolds from Porcine Soft Tissues
ACS Biomaterials Science & Engineering, 6(7), 4200–4213.
author keywords: automation; decellularization; extracellular matrix; hydrogel; biomaterial; biofabrication
MeSH headings : Animals; Biocompatible Materials; Bioreactors; Extracellular Matrix; Hydrogels; Swine; Tissue Scaffolds
TL;DR:
This work presents a versatile, scalable, and automated platform for the rapid production of ECM scaffolds with a biofabrication method for fast and automated derivation of raw material for ECM hydrogel production while preserving ECM composition and controlling lot-to-lot variability.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: June 16, 2020
2020 journal article
Can optical flow perturbations detect walking balance impairment in people with multiple sclerosis?
PLOS ONE, 15(3).
MeSH headings : Accidental Falls / prevention & control; Adult; Biomechanical Phenomena / physiology; Exercise Test / methods; Female; Foot / physiology; Gait / physiology; Humans; Lower Extremity / physiology; Male; Multiple Sclerosis / diagnostic imaging; Multiple Sclerosis / physiopathology; Optic Flow / physiology; Postural Balance / physiology; Virtual Reality; Walking / physiology
TL;DR:
Investigating the effects of optical flow perturbations applied using virtual reality on walking balance in multiple sclerosis revealed differences in Walking balance in PwMS that went undetected during normal, unperturbed walking.
(via Semantic Scholar)
journals.plos.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 15, 2020
2020 article
Neonatal Fibrin Scaffolds Promote Enhanced Cell Adhesion, Migration, and Wound Healing In Vivo Compared to Adult Fibrin Scaffolds
CELLULAR AND MOLECULAR BIOENGINEERING.
TL;DR:
In vivo significantly smaller wound areas and greater epidermal thickness were observed when wounds were treated with neonatal fibrin compared to adultfibrin or a saline control, indicating that fibr in scaffolds sourced from neonatal plasma could improve healing outcomes compared to scaffoldsourced from adult plasma.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 15, 2020
2020 journal article
Engineered PD-L1-Expressing Platelets Reverse New-Onset Type 1 Diabetes
ADVANCED MATERIALS, 32(26).
author keywords: drug delivery; immune tolerance; platelets; programmed death-ligand 1 (PD-L1); type 1 diabetes (T1D)
MeSH headings : Animals; B7-H1 Antigen / genetics; B7-H1 Antigen / metabolism; Blood Glucose / analysis; CD8-Positive T-Lymphocytes / cytology; CD8-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / metabolism; Diabetes Mellitus, Type 1 / pathology; Diabetes Mellitus, Type 1 / therapy; Diabetes Mellitus, Type 1 / veterinary; Genetic Engineering; Immune Tolerance; Insulin / blood; Insulin-Secreting Cells / cytology; Insulin-Secreting Cells / immunology; Insulin-Secreting Cells / metabolism; Megakaryocyte Progenitor Cells / cytology; Megakaryocyte Progenitor Cells / metabolism; Megakaryocyte Progenitor Cells / transplantation; Mice; Mice, Inbred NOD; T-Lymphocytes, Regulatory / cytology; T-Lymphocytes, Regulatory / immunology; T-Lymphocytes, Regulatory / metabolism
TL;DR:
It is demonstrated that the rescue of β‐cells by PD‐L1 platelets can effectively maintain normoglycemia and reverse diabetes in newly hyperglycemic NOD mice.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: June 8, 2020
2020 journal article
Ultrasound Enhanced Synthetic Platelet Therapy for Augmented Wound Repair
ACS BIOMATERIALS SCIENCE & ENGINEERING, 6(5), 3026–3036.
author keywords: biomimetic; fibrin; wound healing clot retraction; artificial platelet
MeSH headings : Blood Coagulation; Blood Platelets; Clot Retraction; Fibrin; Wound Healing
TL;DR:
Application of ultrasound in combination with a subtherapeutic dosage of PLPs resulted in increased clot density and stiffness, improved fibroblast migration in vitro and increased epidermal thickness and angiogenesis in vivo, indicating that this combination therapy has potential to facilitate multiphase pro-healing outcomes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 8, 2020
2020 journal article
Temperature Dependence of High Frequency Irreversible Electroporation Evaluated in a 3D Tumor Model
ANNALS OF BIOMEDICAL ENGINEERING, 48(8), 2233–2246.
author keywords: Nano-knife irreversible electroporation (NK-IRE); Electro thermal therapy; Tissue ablation; Cancer therapy; Integrated energized time (IET); Pulsed electric fields
MeSH headings : Cell Death; Cell Line, Tumor; Cell Survival; Electroporation; Glioblastoma / metabolism; Glioblastoma / pathology; Humans; Models, Biological; Temperature
TL;DR:
Results were found for pancreatic cancer cells which indicate that tissue temperature may be a significant factor affecting H-FIRE ablation size and treatment planning in vivo while lower temperatures may be useful in maintaining cell viability for transfection applications.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 1, 2020
2020 book
Coronary Artery Disease and The Evolution of Angioplasty Devices
In SpringerBriefs in Materials.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: May 27, 2020
2020 journal article
Pooled CRISPR screens with imaging on microraft arrays reveals stress granule-regulatory factors
NATURE METHODS, 17(6), 636-+.
MeSH headings : CRISPR-Cas Systems / genetics; Clustered Regularly Interspaced Short Palindromic Repeats / genetics; Cytoplasm / metabolism; Humans; Machine Learning; Microscopy, Confocal / methods; Oxidative Stress / genetics; Protein Aggregates / genetics; RNA, Guide, Kinetoplastida / genetics; RNA-Binding Proteins / genetics; Tissue Array Analysis / methods
TL;DR:
A machine-learning model trained on nuclear morphology was developed and validated previously uncharacterized RBPs that modulate stress granule abundance, highlighting the applicability of the approach to facilitate image-based pooled CRISPR screens.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 26, 2020
2020 journal article
Superharmonic Ultrasound for Motion-Independent Localization Microscopy: Applications to Microvascular Imaging From Low to High Flow Rates
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 67(5), 957–967.
author keywords: Acoustic angiography (AA); angiogenesis; contrast agent; microbubble (MB); microvasculature; superharmonic imaging (SHI); ultrasound localization microscopy (ULM)
MeSH headings : Angiography; Animals; Female; Image Processing, Computer-Assisted / methods; Kidney / blood supply; Kidney / diagnostic imaging; Microscopy / methods; Microvessels / diagnostic imaging; Movement; Rats; Ultrasonography / methods
TL;DR:
Superharmonic imaging is applied to ULM and an average improvement in SNR of 10.3-dB in vitro when compared with the standard singular value decomposition filter approach and an increase inSNR at low flow from 5 to 16.5 dB.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 26, 2020
2020 article
Nanostructured biomaterials for regenerative medicine: Clinical perspectives
NANOSTRUCTURED BIOMATERIALS FOR REGENERATIVE MEDICINE, pp. 47–80.
TL;DR:
An overview of innovative platform technologies based on nanostructured biomaterials as a function of their material properties as well as their role in tissue engineering and regenerative medicine is provided.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 26, 2020
2020 journal article
Biodegradable Polymers as the Pivotal Player in the Design of Tissue Engineering Scaffolds
Advanced Healthcare Materials, 5, 1901358.
author keywords: biodegradable materials; biomaterials; composites; polymers; tissue engineering scaffolds
MeSH headings : Biocompatible Materials; Polymers; Regenerative Medicine; Tissue Engineering; Tissue Scaffolds
TL;DR:
The interaction between implanted biodegradable biomaterials and the in vivo environment are discussed, including the properties and functional changes of the degradable scaffold, the local effect of degradation on the contiguous tissue and their evaluation using both in vitro and in vivo models.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: May 19, 2020
2020 journal article
Effects of aging and target location on reaction time and accuracy of lateral precision stepping during walking
JOURNAL OF BIOMECHANICS, 104.
author keywords: Elderly; Balance; Foot Placement; Stability; Gait
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Aging; Exercise Test; Foot; Gait; Humans; Male; Postural Balance; Reaction Time; Walking; Young Adult
TL;DR:
This is the first study to show a potential neuromuscular basis for precision stepping deficits in older adults, and suggests that age-related deficits other than those in visuomotor processing contribute to poorer performance for more difficult stepping tasks.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 18, 2020
2020 journal article
Quantitative sub-resolution blood velocity estimation using ultrasound localization microscopy ex-vivo and in-vivo
BIOMEDICAL PHYSICS & ENGINEERING EXPRESS, 6(3).
author keywords: ultrasound imaging; super-resolution; blood flow
MeSH headings : Algorithms; Animals; Blood Flow Velocity; Blood Vessels / diagnostic imaging; Calibration; Contrast Media; Equipment Design; Humans; Image Processing, Computer-Assisted; In Vitro Techniques; Mice; Microbubbles; Microscopy / methods; Microvessels / diagnostic imaging; Phantoms, Imaging; Reproducibility of Results; Signal Processing, Computer-Assisted; Transducers; Ultrasonography / instrumentation; Ultrasonography / methods
TL;DR:
It is shown that the parabolic flow profiles within these micro-vessels are resolvable and velocity measurements are in excellent agreement with theoretical predictions within the considered range of flow rates.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 18, 2020
2020 journal article
Fully-textile Insole Seam-line for Multi-modal Sensor Mapping
IEEE Sensors Journal, 20(17), 1–1.
Contributors: M. McKnight n, J. Tabor n, T. Agcayazi n, A. Fleming n, T. Ghosh n, H. Huang n , A. Bozkurt n
author keywords: Yarn; Sensor arrays; Fabrics; Sensor systems; Foot; Pressure sensors; sensor arrays; multiple-sensor systems; impedance measurement; moisture measurement; multimodal sensors; sensor systems and applications; textiles; wearable sensors
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: ORCID
Added: May 13, 2020
2020 journal article
Evoking haptic sensations in the foot through high-density transcutaneous electrical nerve stimulations
Journal of Neural Engineering, 4(3).
Contributors: L. Pan, L. Vargas, L. Vargas, A. Fleming, A. Fleming, X. Hu, X. Hu, Y. Zhu, H. Huang*
author keywords: haptic sensation; electrical stimulation; transcutaneous nerve stimulation; peripheral nerve; amputee; sensory feedback
MeSH headings : Amputees; Artificial Limbs; Humans; Phantom Limb; Touch; Transcutaneous Electric Nerve Stimulation
TL;DR:
The capability of the non-invasive transcutaneous electrical nerve stimulation method to evoke haptic sensations in the foot of transtibial amputees and the able-bodied subject is demonstrated.
(via Semantic Scholar)
Source: ORCID
Added: May 13, 2020
2020 journal article
Multiplexed Cre-dependent selection yields systemic AAVs for targeting distinct brain cell types
NATURE METHODS, 17(5), 541-+.
MeSH headings : Animals; Blood-Brain Barrier / metabolism; Brain / virology; Capsid Proteins / genetics; Capsid Proteins / metabolism; Dependovirus / genetics; Female; Gene Transfer Techniques; Genetic Engineering / methods; Genetic Therapy; Genetic Vectors / genetics; Integrases / metabolism; Male; Mice; Mice, Inbred C57BL; Organ Specificity; Viral Tropism
TL;DR:
M-CREATE is an in vivo screening strategy for identifying recombinant AAVs with desired tropism that can cross the blood–brain barrier in adult mice across strains when delivered intravenously and accelerates the discovery of capsids for use in neuroscience and gene-therapy applications.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 8, 2020
2020 journal article
Regenerating Antithrombotic Surfaces through Nucleic Acid Displacement
ACS BIOMATERIALS SCIENCE & ENGINEERING, 6(4), 2159–2166.
author keywords: blood-contacting devices; antithrombotic; refillable surface coatings; oligonucleotides; toehold exchange
MeSH headings : Fibrin; Fibrinogen; Fibrinolytic Agents / pharmacology; Nucleic Acids; Regeneration
TL;DR:
This study presents a unique strategy for achieving a continuous antithrombotic state for blood-contacting devices using an ODN-based regeneration method using oligodeoxynucleotide toehold exchange.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: May 8, 2020
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