Works Published in 2018

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Displaying works 1 - 20 of 46 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2018 journal article

The NIEHS TaRGET II Consortium and environmental epigenomics

Nature Biotechnology, 36(3), 225–227.

By: T. Wang*, E. Pehrsson*, D. Purushotham*, D. Li*, X. Zhuo*, B. Zhang, H. Lawson*, M. Province* ...

co-author countries: United States of America 🇺🇸
MeSH headings : Environmental Exposure / adverse effects; Epigenomics; Genome / drug effects; Humans; National Institute of Environmental Health Sciences (U.S.); United States
Source: Crossref
Added: February 24, 2020

2018 journal article

Elucidating Gene-by-Environment Interactions Associated with Differential Susceptibility to Chemical Exposure.

Environmental Health Perspectives, 6(6).

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Embryo, Nonmammalian / drug effects; Embryonic Development / drug effects; Female; Gene-Environment Interaction; Genetic Variation; Genome-Wide Association Study; High-Throughput Screening Assays / methods; Ivermectin / analogs & derivatives; Ivermectin / toxicity; Male; Phenotype; Zebrafish / embryology; Zebrafish / genetics
Source: ORCID
Added: May 14, 2019

2018 journal article

Periconceptional Maternal Mediterranean Diet Is Associated With Favorable Offspring Behaviors and Altered CpG Methylation of Imprinted Genes

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 6.

By: J. House n, M. Mendez*, R. Maguire n, S. Gonzalez-Nahm*, Z. Huang*, J. Daniels*, S. Murphy*, B. Fuemmeler*, F. Wright n, C. Hoyo n

co-author countries: United States of America 🇺🇸
Source: NC State University Libraries
Added: January 21, 2019

2018 journal article

Identification of Cytauxzoon felis antigens via protein microarray and assessment of expression library immunization against cytauxzoonosis

CLINICAL PROTEOMICS, 15(1).

By: M. Schreeg n, H. Marr n, J. Tarigo n, M. Sherrill*, H. Outi*, E. Scholl n, D. Bird n, A. Vigil* ...

co-author countries: Australia 🇦🇺 United States of America 🇺🇸

Contributors: M. Schreeg n, H. Marr n, J. Tarigo n, M. Sherrill*, H. Outi*, E. Scholl n, D. Bird n, A. Vigil* ...

author keywords: Cytauxzoonosis; Cytauxzoon felis; Expression library immunization; Protein microarray; Piroplasmid; Vaccine
Sources: Web Of Science, ORCID
Added: January 14, 2019

2018 journal article

Chemistry-Wide Association Studies (CWAS): A Novel Framework for Identifying and Interpreting Structure-Activity Relationships

JOURNAL OF CHEMICAL INFORMATION AND MODELING, 58(11), 2203–2213.

co-author countries: Brazil 🇧🇷 Ukraine 🇺🇦 United States of America 🇺🇸
MeSH headings : Databases, Factual; Drug Discovery / methods; Drug-Related Side Effects and Adverse Reactions / etiology; Humans; Models, Biological; Mutagenicity Tests / methods; Pharmaceutical Preparations / chemistry; Quantitative Structure-Activity Relationship; Stevens-Johnson Syndrome / etiology
Source: Web Of Science
Added: December 17, 2018

2018 journal article

A Human Population-Based Organotypic In Vitro Model for Cardiotoxicity Screening

ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 35(4), 441–452.

By: F. Grimm*, A. Blanchette*, J. House n, K. Ferguson*, N. Hsieh*, C. Dalaijamts*, A. Wright*, B. Anson* ...

co-author countries: United States of America 🇺🇸
MeSH headings : Cardiotoxicity / genetics; Cardiovascular Agents / pharmacology; Cardiovascular Agents / toxicity; Cell Differentiation / drug effects; Cell Differentiation / genetics; Female; Healthy Volunteers; Humans; In Vitro Techniques; Induced Pluripotent Stem Cells / cytology; Induced Pluripotent Stem Cells / drug effects; Male; Myocytes, Cardiac / drug effects; Myocytes, Cardiac / physiology; Phenotype; Reproducibility of Results
Source: Web Of Science
Added: December 10, 2018

2018 journal article

chemmodlab: a cheminformatics modeling laboratoryR package for fitting and assessing machine learning models

JOURNAL OF CHEMINFORMATICS, 10.

co-author countries: United States of America 🇺🇸
author keywords: Machine learning; QSAR; R package; Initial enhancement; Enrichment factor; Accumulation curve; Hit enrichment curve; Repeated cross-validation
Source: Web Of Science
Added: December 10, 2018

2018 journal article

Neonatal mice exposed to a high-fat diet in utero influence the behaviour of their nursing dam

By: M. Baptissart n, H. Lamb n, K. To n, C. Bradish n, J. Tehrani n, D. Reif n, M. Cowley n

co-author countries: United States of America 🇺🇸

Contributors: M. Baptissart n, H. Lamb n, K. To n, C. Bradish n, J. Tehrani n, D. Reif n, M. Cowley n

MeSH headings : Animals; Animals, Newborn / physiology; Diet, High-Fat; Female; Maternal Behavior / physiology; Maternal Exposure; Mice / physiology; Mice, Inbred C57BL; Pregnancy
Sources: NC State University Libraries, ORCID
Added: December 10, 2018

2018 journal article

Exploring drug space with ChemMaps.com

BIOINFORMATICS, 34(21), 3773–3775.

co-author countries: United States of America 🇺🇸
MeSH headings : Computational Biology; Databases, Pharmaceutical; Molecular Structure; Software; Web Browser
Source: Web Of Science
Added: December 3, 2018

2018 journal article

Toward the Rational Design of Sustainable Hair Dyes Using Cheminformatics Approaches: Step 2. Identification of Hair Dye Substance Database Analogs in the Max Weaver Dye Library

ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 6(11), 14248–14256.

co-author countries: United States of America 🇺🇸
author keywords: Cheminformatics; Hair dyes; Hair Dye Substance Database; Max Weaver Dye Library; Skin sensitization; Sustainability
Source: Web Of Science
Added: December 3, 2018

2018 journal article

Cheminformatics-based enumeration and analysis of large libraries of macrolide scaffolds

JOURNAL OF CHEMINFORMATICS, 10.

By: P. Zin n, G. Williams n & D. Fourches n

co-author countries: United States of America 🇺🇸
Source: Web Of Science
Added: December 3, 2018

2018 journal article

Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial

DIABETES CARE, 41(11), 2404–2413.

By: M. Morieri*, H. Gao*, M. Pigeyre*, H. Shah*, J. Sjaarda*, C. Mendonca*, T. Hastings*, P. Buranasupkajorn* ...

co-author countries: Canada 🇨🇦 Thailand 🇹🇭 United States of America 🇺🇸
MeSH headings : Aged; Cohort Studies; Coronary Artery Disease / diagnosis; Coronary Artery Disease / genetics; Coronary Artery Disease / prevention & control; Diabetes Mellitus, Type 2 / complications; Diabetes Mellitus, Type 2 / diagnosis; Diabetes Mellitus, Type 2 / drug therapy; Diabetes Mellitus, Type 2 / genetics; Diabetic Angiopathies / diagnosis; Diabetic Angiopathies / genetics; Diabetic Angiopathies / prevention & control; Female; Fenofibrate / administration & dosage; Genetic Association Studies; Genetic Markers; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Molecular Diagnostic Techniques; Polymorphism, Single Nucleotide; Risk Assessment; Risk Factors; Simvastatin / administration & dosage
Source: Web Of Science
Added: November 5, 2018

2018 journal article

The influence of Neanderthal alleles on cytotoxic response

PEERJ, 6.

co-author countries: Japan 🇯🇵 United States of America 🇺🇸
author keywords: Neanderthal alleles; Cytotoxic response; Pharmacogenomics; Toxicogenomics; Dose responses; Neanderthal ancestry; Lymphoblastoid cell lines; Anti-cancer drugs; Environmental chemicals; Single nucleotide polymorphisms
Source: Web Of Science
Added: November 5, 2018

2018 journal article

Predicting Adverse Drug Effects from Literature- and Database-Mined Assertions

DRUG SAFETY, 41(11), 1059–1072.

By: M. La*, A. Sedykh*, D. Fourches n, E. Muratov & A. Tropsha

co-author countries: United States of America 🇺🇸
MeSH headings : Data Mining / methods; Databases, Factual; Drug-Related Side Effects and Adverse Reactions / epidemiology; Humans; Prescription Drugs / adverse effects; Prescription Drugs / pharmacology; Proteins / drug effects
Source: Web Of Science
Added: October 29, 2018

2018 journal article

Pharmacometabolomics Informs About Pharmacokinetic Profile of Methylphenidate

CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY, 7(8), 525–533.

By: R. Kaddurah-Daouk*, T. Hankemeier*, E. Scholl n, R. Baillie*, A. Harms*, C. Stage*, K. Dalhoff*, G. Jurgens* ...

co-author countries: Denmark 🇩🇰 France 🇫🇷 Netherlands 🇳🇱 United States of America 🇺🇸
MeSH headings : Adult; Central Nervous System Stimulants / pharmacokinetics; Female; Humans; Male; Methylphenidate / pharmacokinetics; Prospective Studies; Young Adult
Source: NC State University Libraries
Added: October 16, 2018

2018 journal article

Estimation of cis-eQTL effect sizes using a log of linear model

BIOMETRICS, 74(2), 616–625.

By: J. Palowitch*, A. Shabalin*, Y. Zhou n, A. Nobel* & F. Wright n

co-author countries: United States of America 🇺🇸
author keywords: eQTL analyses; EQTL effect size; Multiple testing; Nonlinear regression
MeSH headings : Algorithms; Alleles; Gene Expression; Humans; Linear Models; Quantitative Trait Loci; Statistics as Topic
Source: Web Of Science
Added: October 16, 2018

2018 journal article

Polyphasic characterization of four soil-derived phenanthrene-degrading Acidovorax strains and proposal of Acidovorax carolinensis sp nov.

SYSTEMATIC AND APPLIED MICROBIOLOGY, 41(5), 460–472.

By: D. Singleton*, J. Lee*, A. Dickey n, A. Stroud*, E. Scholl n, F. Wright n, M. Aitken*

co-author countries: United States of America 🇺🇸
author keywords: Acidovorax; Phenanthrene; Polycyclic aromatic hydrocarbons
MeSH headings : Biodegradation, Environmental; Comamonadaceae / chemistry; Comamonadaceae / classification; Comamonadaceae / genetics; Comamonadaceae / physiology; DNA, Bacterial; Genes, Bacterial; Genome, Bacterial / genetics; Metabolic Networks and Pathways / genetics; North Carolina; Phenanthrenes / metabolism; Phylogeny; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Soil Microbiology; Soil Pollutants / metabolism
Source: Web Of Science
Added: October 16, 2018

2018 journal article

Permissiveness to form pluripotent stem cells may be an evolutionarily derived characteristic in Mus muscuius

SCIENTIFIC REPORTS, 8.

By: T. Garbutt n, T. Konneker n, K. Konganti*, A. Hillhouse*, F. Swift-Haire n, A. Jones n, D. Phelps n, D. Aylor n, D. Threadgill*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Cells, Cultured; Cellular Reprogramming / drug effects; Cellular Reprogramming / genetics; Culture Media / metabolism; Culture Media / pharmacology; Evolution, Molecular; Female; Fibroblasts; Glycogen Synthase Kinase 3 beta / antagonists & inhibitors; Glycogen Synthase Kinase 3 beta / metabolism; Induced Pluripotent Stem Cells; Leukemia Inhibitory Factor / metabolism; MAP Kinase Kinase Kinases / antagonists & inhibitors; MAP Kinase Kinase Kinases / metabolism; Male; Mice / genetics; Mice, Inbred Strains / genetics; Mouse Embryonic Stem Cells; Primary Cell Culture; Protein Kinase Inhibitors / pharmacology; Sex Factors; Transcription, Genetic
Source: Web Of Science
Added: October 16, 2018

2018 journal article

Chemical-Induced Phenotypes at CTD Help Inform the Predisease State and Construct Adverse Outcome Pathways

TOXICOLOGICAL SCIENCES, 165(1), 145–156.

co-author countries: United States of America 🇺🇸
author keywords: phenotype; database; curation; chemical; disease; adverse outcome pathway
MeSH headings : Adverse Outcome Pathways; Animals; Databases, Factual; Drug-Related Side Effects and Adverse Reactions / genetics; Gene Ontology; Gene-Environment Interaction; Humans; Phenotype; Toxicogenetics / methods
Source: Web Of Science
Added: October 16, 2018

2018 journal article

Confirmation of high-throughput screening data and novel mechanistic insights into VDR-xenobiotic interactions by orthogonal assays

Scientific Reports, 8(1).

co-author countries: United States of America 🇺🇸

Contributors: D. Mahapatra n, J. Franzosa*, K. Roell n, M. Kuenemann n, K. Houck*, D. Reif n, D. Fourches n, S. Kullman n

MeSH headings : Drug Evaluation, Preclinical; Genes, Reporter; High-Throughput Screening Assays; Humans; Luciferases / analysis; Luciferases / genetics; Protein Binding; Receptors, Calcitriol / agonists; Receptors, Calcitriol / antagonists & inhibitors; Two-Hybrid System Techniques; Xenobiotics / metabolism
Sources: Crossref, ORCID, NC State University Libraries
Added: August 6, 2018

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