Works Published in 2008

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Displaying works 61 - 80 of 158 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2008 journal article

Regiospecifically alpha-C-13-labeled porphyrins for studies of ground-state hole transfer in multiporphyrin arrays

JOURNAL OF ORGANIC CHEMISTRY, 73(18), 6947–6959.

MeSH headings : Carbon Isotopes; Electrochemistry; Electron Spin Resonance Spectroscopy / methods; Electrons; Metalloporphyrins / chemical synthesis; Metalloporphyrins / chemistry; Models, Chemical; Molecular Structure; Porphyrins / chemistry; Quantum Theory; Stereoisomerism; Zinc / chemistry
TL;DR: Examination of the monocation of the isotopically labeled dyad via electron paramagnetic resonance (EPR) spectroscopy showed that the hole transfer between porphyrin constituents of the dyad is slow on the EPR time scale at room temperature. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2008 journal article

Neurogenetic networks for startle-induced locomotion in Drosophila melanogaster

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 105(34), 12393–12398.

By: A. Yamamoto n, L. Zwarts*, P. Callaerts*, K. Norga*, T. Mackay n & R. Anholt n

author keywords: behavioral genetics; epistasis; sensorimotor integration; startle behavior; P-element insertional mutagenesis
MeSH headings : Animals; DNA Transposable Elements; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Epistasis, Genetic; Gene Regulatory Networks / physiology; Locomotion / genetics; Locomotion / physiology; Mutation; Nervous System Physiological Phenomena; Reflex, Startle / genetics; Reflex, Startle / physiology
TL;DR: It is found that behavioral and neuroanatomical phenotypes are determined by a common set of genes that are organized as partially overlapping genetic networks. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Investigation of the scope of a new route to ABCD-bilanes and ABCD-porphyrins

JOURNAL OF ORGANIC CHEMISTRY, 73(17), 6728–6742.

MeSH headings : Acids / chemistry; Alkanes / chemistry; Catalysis; Magnesium Compounds / chemistry; Metals / chemistry; Microwaves; Models, Chemical; Porphyrins / chemical synthesis; Solvents / chemistry; Stereoisomerism; Temperature; Toluene / chemistry
TL;DR: A new route providing access to meso-substituted bilanes and porphyrins for which access is limited via other methods is studied to elucidate the scope and gain entry to previously inaccessible compounds. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2008 review

Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection

[Review of ]. Plant Physiology, 148(1), 436–454.

By: J. Ascencio-Ibanez, R. Sozzani, T. Lee, T. Chu, R. Wolfinger, R. Cella, L. Hanley-Bowdoin

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

Geminivirus-mediated gene silencing from Cotton leaf crumple virus is enhanced by low temperature in cotton

PLANT PHYSIOLOGY, 148(1), 41–50.

By: J. Tuttle n, A. Idris n, J. Brown n, C. Haigler n & D. Robertson n

MeSH headings : Animals; Capsid Proteins / physiology; Cold Temperature; DNA, Viral / analysis; Flowers / chemistry; Geminiviridae / physiology; Gene Silencing; Genetic Markers; Genetic Vectors / analysis; Genetic Vectors / physiology; Gossypium / chemistry; Gossypium / virology; Host-Pathogen Interactions; Insect Vectors / physiology; Plant Diseases / virology; Plant Leaves / chemistry; Plant Roots / chemistry
TL;DR: The experiments establish the use of the CLCrV silencing vector to study gene function in cotton and show that temperature can have a major impact on the extent of geminivirus-induced gene silencing. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2008 article

Functional genomics of probiotic Lactobacilli

Klaenhammer, T. R., Altermann, E., Pfeiler, E., Buck, B. L., Goh, Y.-J., O'Flaherty, S., … Duong, T. (2008, September). JOURNAL OF CLINICAL GASTROENTEROLOGY, Vol. 42, pp. S160–S162.

author keywords: Lactobacillus acidophilus; Lactobacillus johnsonii; Lactobacillus plantarum; Lactobacillus gasseri; genomics; probiotic cultures; lactic acid bacteria
MeSH headings : Animals; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Evolution, Molecular; Genome, Bacterial; Genomics; Humans; Lactobacillus / classification; Lactobacillus / genetics; Lactobacillus / metabolism; Lactobacillus / physiology; Probiotics / metabolism; Species Specificity
TL;DR: A comparative genomic analysis of 4 completely sequenced Lactobacillus strains versus 25 lactic acid bacterial genomes present in the public database at thetime of analysis is conducted. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2008 journal article

C/EBP beta represses p53 to promote cell survival downstream of DNA damage independent of oncogenic Ras and p19(Arf)

CELL DEATH AND DIFFERENTIATION, 15(11), 1734–1744.

author keywords: apoptosis; p53; C/EBP beta; p19(Arf); DNA damage; keratinocytes
MeSH headings : Animals; Apoptosis / drug effects; CCAAT-Enhancer-Binding Protein-beta / deficiency; CCAAT-Enhancer-Binding Protein-beta / metabolism; Carcinogens / toxicity; Cell Survival / drug effects; Cyclin-Dependent Kinase Inhibitor p16 / metabolism; Cyclophosphamide / administration & dosage; Cyclophosphamide / pharmacology; DNA Damage; Epidermal Cells; Epidermis / drug effects; Epidermis / metabolism; Injections, Intraperitoneal; Keratinocytes / cytology; Keratinocytes / drug effects; Keratinocytes / metabolism; Mice; Oncogene Protein p21(ras) / metabolism; Protein Processing, Post-Translational / drug effects; Repressor Proteins / metabolism; Transcriptional Activation / drug effects; Tumor Suppressor Protein p53 / genetics; Tumor Suppressor Protein p53 / metabolism
TL;DR: Results suggest that inhibition of C/EBPβ may be a target for cancer cotherapy to increase the efficacy of alkylating chemotherapeutic agents and suggest that p19Arf represses p53 to promote cell survival downstream of DNA damage. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2008 journal article

Anti-Mullerian hormone and inhibin B in the definition of ovarian aging and the menopause transition

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 93(9), 3478–3483.

By: M. Sowers*, A. Eyvazzadeh*, D. McConnell*, M. Yosef*, M. Jannausch*, D. Zhang n, S. Harlow*, J. Randolph*

MeSH headings : Adult; Aging / blood; Aging / physiology; Anti-Mullerian Hormone / blood; Anti-Mullerian Hormone / physiology; Biomarkers / blood; Cohort Studies; Female; Follicle Stimulating Hormone / blood; Forecasting; Humans; Inhibins / blood; Inhibins / physiology; Menopause / blood; Menopause / physiology; Menstruation / blood; Middle Aged; Models, Biological; Ovary / physiology
TL;DR: AMH, an endocrine marker that reflects the transition of resting primordial follicles to growing follicles, declined to a time point 5 yr prior to the FMP; this may represent a critical biological juncture in the menopause transition. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Comparison of Electron-Transfer Rates for Metal- versus Ring-Centered Redox Processes of Porphyrins in Monolayers on Au(111)

LANGMUIR, 24(20), 12047–12053.

By: J. Jiao n, I. Schmidt n, M. Taniguchi n, J. Lindsey n & D. Bocian n

TL;DR: The faster rates for the ring- versus metal-centered redox process are attributed to the participating molecular orbitals and their proximity to the surface (given that the porphyrins are relatively upright on the surface): a pi molecular orbital that has significant electron density at the meso-carbon atoms. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2008 journal article

Sequential transphosphorylation of the BRI1/BAK1 receptor kinase complex impacts early events in brassinosteroid signaling

DEVELOPMENTAL CELL, 15(2), 220–235.

By: X. Wang n, U. Kota n, K. He*, K. Blackburn n, J. Li*, M. Goshe n, S. Huber*, S. Clouse n

MeSH headings : Amino Acid Sequence; Arabidopsis / drug effects; Arabidopsis / enzymology; Arabidopsis Proteins / chemistry; Arabidopsis Proteins / metabolism; Brassinosteroids; Cholestanols / metabolism; Cholestanols / pharmacology; Chromatography, Liquid; Flagellin / metabolism; Mass Spectrometry; Models, Biological; Molecular Sequence Data; Mutation / genetics; Phosphorylation / drug effects; Protein Kinases / chemistry; Protein Kinases / metabolism; Protein Serine-Threonine Kinases / chemistry; Protein Serine-Threonine Kinases / metabolism; Protein Structure, Tertiary; Signal Transduction / drug effects; Steroids, Heterocyclic / metabolism; Steroids, Heterocyclic / pharmacology; Substrate Specificity / drug effects
TL;DR: A sequential transphosphorylation model in which BRI1 controls signaling specificity by direct BR binding followed by substrate phosphorylation is proposed, which suggests both conservation and distinct differences between the molecular mechanisms regulating phosphorylated-dependent kinase activation in plant and animal receptor kinases. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Fitness of isolates of Phytophthora capsici resistant to mefenoxam from squash and pepper fields in North Carolina

PLANT DISEASE, 92(10), 1439–1443.

Contributors: A. Café-Filho* & J. Ristaino n

author keywords: fungicide resistance; metalaxyl; oomycetes; phenylamides; stramenopiles
TL;DR: Mefenoxam-resistant isolates from squash were as aggressive on pepper as sensitive or resistant pepper isolates, suggesting that mefenoxAM-resistant populations of P. capsici are as virulent and fit as sensitive populations. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2008 journal article

Epibulbar melanoma in a foal

VETERINARY OPHTHALMOLOGY, 11, 44–50.

By: R. McMullen, A. Clode*, A. Pandiri n, D. Malarkey*, T. Michau* & B. Gilger*

author keywords: congenital; epibulbar; equine; melanoma; neoplasia
MeSH headings : Animals; Animals, Newborn; Choroid Neoplasms / pathology; Choroid Neoplasms / surgery; Choroid Neoplasms / veterinary; Eye Enucleation / methods; Eye Enucleation / veterinary; Eye Neoplasms / pathology; Eye Neoplasms / surgery; Eye Neoplasms / veterinary; Horse Diseases / pathology; Horse Diseases / surgery; Horses; Limbus Corneae; Macrophages / pathology; Male; Melanoma / pathology; Melanoma / surgery; Melanoma / veterinary; Pigment Epithelium of Eye / pathology; Treatment Outcome
TL;DR: Based on the sudden onset and rapid growth as well as the histological evidence of invasion, well-differentiated features, heavy pigmentation, and no apparent mitoses, this neoplasm was considered to be a low-grade malignant melanoma. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2008 article

Acute HIV-1 infection: targeting the regulator

Dean, G. (2008, October 1). BLOOD, Vol. 112, pp. 2600–2600.

By: G. Dean n

TL;DR: The use of humanized rag2-/-γC-/- mice is described to demonstrate the preferential infection and depletion of Tregs during acute HIV-1 infection. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Serum Cardiac Troponin I Concentration in Dogs with Ehrlichiosis

Journal of Veterinary Internal Medicine, 22(5), 1136–1143.

By: P. Diniz n, H. de Morais*, E. Breitschwerdt n & D. Schwartz*

author keywords: canine monocytic ehrlichiosis; myocarditis; risk factor; SIRS; troponin
MeSH headings : Animals; Biomarkers / blood; Dog Diseases / blood; Dogs; Ehrlichiosis / blood; Ehrlichiosis / veterinary; Female; Heart Diseases / blood; Heart Diseases / complications; Heart Diseases / veterinary; Male; Odds Ratio; Risk Factors; Troponin I / blood
TL;DR: Severity of anemia and SIRS might contribute to the pathophysiology of myocardial damage in naturally infected Brazilian dogs. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2008 journal article

Pleiotropic effects of Drosophila neuralized on complex behaviors and brain structure

GENETICS, 179(3), 1327–1336.

By: S. Rollmann n, L. Zwarts*, A. Edwards n, A. Yamamoto n, P. Callaerts*, K. Norga*, T. Mackay n, R. Anholt n

MeSH headings : Alleles; Alternative Splicing / genetics; Animals; Behavior; Brain / anatomy & histology; DNA Transposable Elements; Drosophila Proteins / genetics; Drosophila Proteins / metabolism; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Female; Gene Expression Regulation, Developmental; Genes, Insect; Male; Mutagenesis, Insertional; Mutation / genetics; RNA, Messenger / genetics; RNA, Messenger / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Ubiquitin-Protein Ligases / genetics; Ubiquitin-Protein Ligases / metabolism
TL;DR: The diverse phenotypic effects arising from nearby P-element insertions in neur provide a new appreciation of the concept of allelic effects on phenotype, in which the wild type and null mutant are at the extreme ends of a continuum of pleiotropic allelic Effects. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Failure to identify an association between serologic or molecular evidence ofBartonellainfection and idiopathic rhinitis in dogs

Journal of the American Veterinary Medical Association, 233(4), 597–599.

By: E. Hawkins n, L. Johnson, L. Guptill*, H. Marr n, E. Breitschwerdt n & A. Birkenheuer n

MeSH headings : Animals; Antibodies, Bacterial / blood; Bartonella / immunology; Bartonella / isolation & purification; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Bartonella henselae / immunology; Bartonella henselae / isolation & purification; Case-Control Studies; DNA, Bacterial / analysis; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Female; Fluorescent Antibody Technique, Indirect / methods; Fluorescent Antibody Technique, Indirect / veterinary; Male; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; Rhinitis / diagnosis; Rhinitis / microbiology; Rhinitis / veterinary
TL;DR: The failure to find any evidence of exposure to or infection with Bartonella spp in dogs with idiopathic nasal discharge suggested that Bart onella infection was not a common cause of the disease. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2008 journal article

Enhancement of extra chromosomal recombination in somatic cells by affecting the ratio of homologous recombination (HR) to non-homologous end joining (NHEJ)

ANIMAL BIOTECHNOLOGY, 19(1), 6–21.

By: G. Zaunbrecher*, B. Mir*, P. Dunne n, M. Breen n & J. Piedrahita n

author keywords: extra chromosomal; homologous recombination; somatic cells
MeSH headings : Acetyltransferases / genetics; Animals; Cell Physiological Phenomena; Chromosomes / genetics; DNA Primers; DNA Repair; Plasmids; Recombination, Genetic; Swine; Tumor Suppressor Protein p53 / genetics
TL;DR: Results show that attempts at reducing NHEJ by use of Mre11 or anti-Ku aptamers were unsuccessful, and cell synchrony via thymidine incorporation does increase the ratio of HR/NHEJ and this indicates that this approach may be of use to facilitate targeting in somatic cells by reducing the numbers of colonies that need to be analyzed before a HR is identified. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2008 article

Analysis of the genome sequence of Lactobacillus gasseri ATCC 33323 reveals the molecular basis of an autochthonous intestinal organism

Azcarate-Peril, M. A., Altermann, E., Goh, Y. J., Tallon, R., Sanozky-Dawes, R. B., Pfeiler, E. A., … Klaenhammer, T. R. (2008, August). APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Vol. 74, pp. 4610–4625.

By: M. Azcarate-Peril n, E. Altermann n, Y. Goh n, R. Tallon n, R. Sanozky-Dawes n, E. Pfeiler n, S. O'Flaherty n, B. Buck n ...

MeSH headings : Adult; Bacterial Adhesion / genetics; Bacterial Adhesion / physiology; Bacterial Proteins / genetics; Child; DNA Primers; Gastrointestinal Tract / microbiology; Genes, Bacterial; Genome, Bacterial; Humans; Infant, Newborn; Intestines / microbiology; Lactobacillus / genetics; Lactobacillus / isolation & purification; Lactobacillus / pathogenicity; Open Reading Frames
TL;DR: The results from this study indicated high intraspecies variability from a genome encoding traits important for survival and retention in the gastrointestinal tract. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

A Listeria monocytogenes mutant defective in bacteriophage attachment is attenuated in orally inoculated mice and impaired in enterocyte intracellular growth

INFECTION AND IMMUNITY, 76(9), 4046–4054.

By: P. Spears n, M. Suyemoto n, A. Palermo n, J. Horton n, T. Hamrick*, E. Havell n, P. Orndorff n

MeSH headings : Animals; Bacterial Adhesion; Bacteriophages / physiology; DNA Transposable Elements; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Enterocytes / microbiology; Female; Genetic Complementation Test; Glycosyltransferases / genetics; Listeria monocytogenes / pathogenicity; Listeria monocytogenes / virology; Listeriosis / microbiology; Liver / microbiology; Mice; Mice, Inbred A; Molecular Sequence Data; Mutagenesis, Insertional; Receptors, Virus / genetics; Sequence Analysis, DNA; Spleen / microbiology; Survival Analysis; Viral Plaque Assay; Virulence; Virulence Factors / genetics; Virus Attachment
TL;DR: Interestingly, the glcV lesion, while preventing phage attachment, did not alter the mutant's ability to bind to cultured mouse enterocyte monolayers, rather, the mutation appeared to alter a subsequent step in intracellular replication measured by a reduction in plaque-forming efficiency and plaque size. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Examination of chlorin-bacteriochlorin energy-transfer dyads as prototypes for near-infrared molecular imaging probes

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 84(5), 1061–1072.

MeSH headings : Dimethyl Sulfoxide / chemistry; Energy Transfer; Fluorescent Dyes / chemistry; Metalloporphyrins / chemical synthesis; Metalloporphyrins / chemistry; Molecular Probes / analysis; Molecular Probes / chemistry; Molecular Structure; Photochemistry; Porphyrins / chemistry; Spectroscopy, Near-Infrared; Stereoisomerism; Toluene / chemistry
TL;DR: The narrow spectral widths enabled excellent selectivity in excitation and detection of one chlorin–bacteriochlorin energy‐transfer dyad in the presence of the other upon diffuse optical tomography of solution‐phase phantoms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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