Works Published in 2004
Displaying works 41 - 60 of 102 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2004 article
Outcome of cats with diarrhea and Tritrichomonas foetus infection
Foster, D. M., Gookin, J. L., Poore, M. F., Stebbins, M. E., & Levy, M. G. (2004, September 15). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 225, pp. 888–892.
MeSH headings : Animals; Antiprotozoal Agents / therapeutic use; Cat Diseases / drug therapy; Cat Diseases / parasitology; Cats; DNA, Protozoan / analysis; DNA, Ribosomal / analysis; Diarrhea / drug therapy; Diarrhea / parasitology; Diarrhea / veterinary; Female; Male; Paromomycin / therapeutic use; Polymerase Chain Reaction / veterinary; Prospective Studies; Protozoan Infections / drug therapy; Protozoan Infections / parasitology; Protozoan Infections, Animal; Time Factors; Treatment Outcome; Tritrichomonas foetus / isolation & purification; Tritrichomonas foetus / pathogenicity
TL;DR:
Results suggested chronic T. foetus-associated diarrhea in most cats is likely to resolve spontaneously within 2 years of onset, and attempts to treat cats with T.foetus infection may result in prolongation of time to resolution of diarrhea.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2004 journal article
Conservation of genomic imprinting at the XIST, IGF2, and GTL2 loci in the bovine
Mammalian Genome, 15(12), 966–974.
MeSH headings : Alleles; Animals; Base Sequence; Cattle; DNA Methylation; Female; Gene Expression Regulation; Genomic Imprinting / genetics; Humans; Insulin-Like Growth Factor II / genetics; Male; Molecular Sequence Data; Placenta; Polymorphism, Single Nucleotide; Proteins / genetics; RNA, Long Noncoding; RNA, Untranslated / genetics; Sequence Homology, Nucleic Acid; Sheep
TL;DR:
Conservation of genomic imprinting in the bovine is reported at the X chromosome inactivation–specific transcript (XIST), insulin-like growth factor 2 (IGF2), and gene trap locus 2 (GTL2) loci.
(via Semantic Scholar)
citeseerx.ist.psu.edu (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2004 journal article
A mixture of the "antiandrogens" linuron and butyl benzyl phthalate alters sexual differentiation of the male rat in a cumulative fashion
BIOLOGY OF REPRODUCTION, 71(6), 1852–1861.
author keywords: androgen receptor; male reproductive tract; male sexual function; testosterone; toxicology
MeSH headings : Anal Canal / anatomy & histology; Androgen Antagonists / administration & dosage; Androgen Antagonists / pharmacology; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Female; Fetus / metabolism; Genitalia, Male / anatomy & histology; Genitalia, Male / embryology; Linuron / administration & dosage; Linuron / pharmacology; Male; Osmolar Concentration; Phthalic Acids / administration & dosage; Phthalic Acids / pharmacology; Pregnancy; Prenatal Exposure Delayed Effects; Progesterone / metabolism; Rats; Rats, Sprague-Dawley; Sex Differentiation / drug effects; Testis / metabolism; Testosterone / metabolism
TL;DR:
Treatment-related changes to neonatal AGD and infant areolae significantly correlated with adult AGD, nipple retention, reproductive malformations, and reproductive organ and tissue weights provide additional evidence of cumulative effects of antiandrogen mixtures on male reproductive development.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2004 journal article
Physiological concentrations of bile salts inhibit recovery of ischemic-injured porcine ileum
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 287(2), G399–G407.
author keywords: mucosa; barrier function; deoxycholic acid; tight junction
MeSH headings : Animals; Bile Acids and Salts / analysis; Calcium / metabolism; Deoxycholic Acid / pharmacology; Female; Ileum / blood supply; Ileum / chemistry; Ileum / pathology; Ileum / physiopathology; Ischemia / metabolism; Ischemia / pathology; Ischemia / physiopathology; Male; Microscopy, Electron; Osmolar Concentration; Permeability / drug effects; Recovery of Function / drug effects; Swine; Taurodeoxycholic Acid / pharmacology
TL;DR:
Deoxycholic acid at physiological concentrations significantly impairs recovery of epithelial barrier function by an effect on paracellular pathways, and these effects appear to be Ca(2+) dependent.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2004 personal communication
Pharm profile considerations
Source: NC State University Libraries
Added: August 6, 2018
2004 journal article
Effect of NF-kappa B inhibition on TNF-alpha-induced apoptosis in human RPE cells
Investigative Ophthalmology and Visual Science, 45(7), 2438–2446.
Source: NC State University Libraries
Added: August 6, 2018
2004 journal article
Caspase inhibition protects against reovirus-induced myocardial injury in vitro and in vivo
JOURNAL OF VIROLOGY, 78(20), 11040–11050.
MeSH headings : Animals; Apoptosis; Caspase 3; Caspase Inhibitors; Caspases / genetics; Caspases / metabolism; Heart / virology; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocarditis / mortality; Myocarditis / pathology; Myocarditis / prevention & control; Myocarditis / virology; Myocardium / pathology; Reoviridae / pathogenicity; Viral Load
TL;DR:
This study indicates that apoptosis plays a critical role in mediating cardiac injury in the setting of viral myocarditis and is the first demonstration that caspase inhibition may serve as a novel therapeutic strategy for this devastating disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2004 journal article
An integrated 4249 marker FISH/RH map of the canine genome
BMC GENOMICS, 5.
MeSH headings : Animals; Chromosome Mapping / methods; Chromosomes, Artificial, Bacterial; Dogs / genetics; Genetic Markers; Genome; Humans; In Situ Hybridization, Fluorescence; Microsatellite Repeats; Radiation Hybrid Mapping; Synteny
TL;DR:
An integrated canine genome map that is both dense and accurate is constructed, allowing the identification of 79 conserved segments between the dog and human genomes, dramatically extending the length of most previously described CS.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2004 journal article
Resolution of the novel immune-type receptor gene cluster in zebrafish
Proceedings of the National Academy of Sciences, 101(44), 15706–15711.
MeSH headings : Alleles; Alternative Splicing; Amino Acid Sequence; Animals; Chromosome Mapping; DNA, Complementary / genetics; Evolution, Molecular; Genetic Variation; Lectins, C-Type / chemistry; Lectins, C-Type / genetics; Models, Molecular; Molecular Sequence Data; Multigene Family; Phylogeny; Protein Structure, Tertiary; Receptors, Immunologic / chemistry; Receptors, Immunologic / genetics; Zebrafish / genetics; Zebrafish / immunology; Zebrafish Proteins / chemistry; Zebrafish Proteins / genetics; Zebrafish Proteins / immunology
TL;DR:
It is indicated that the NITRs represent the most complex family of activating/inhibitory surface receptors thus far described in zebrafish, and high-confidence modeling of Nitr V-domain structures reveals a significant shift in the spatial orientation of the Ig fold, in the region of highest interfamily variation, compared with Ig V domains.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2004 review
Pharmacology of catamenial epilepsy
[Review of ]. Methods and Findings in Experimental and Clinical Pharmacology, 26(7), 547–561.
Source: NC State University Libraries
Added: August 6, 2018
2004 journal article
Pharmacokinetics of enrofloxacin after single-dose oral and intravenous administration in the American alligator (Alligator mississippiensis)
JOURNAL OF ZOO AND WILDLIFE MEDICINE, 35(3), 333–340.
author keywords: American alligator; Alligator mississippiensis; pharmacokinetics; enrofloxacin; ciprofloxacin; oral; antibiotic
MeSH headings : Administration, Oral; Alligators and Crocodiles / blood; Alligators and Crocodiles / metabolism; Animals; Animals, Wild / metabolism; Anti-Infective Agents / administration & dosage; Anti-Infective Agents / pharmacokinetics; Area Under Curve; Chromatography, High Pressure Liquid / methods; Chromatography, High Pressure Liquid / veterinary; Enrofloxacin; Fluoroquinolones / administration & dosage; Fluoroquinolones / pharmacokinetics; Injections, Intravenous / veterinary; Microbial Sensitivity Tests / veterinary; Quinolones / administration & dosage; Quinolones / pharmacokinetics; Random Allocation
TL;DR:
Enrofloxacin administered to American alligators at 5 mg/kg p.o.v. is expected to maintain plasma concentrations that approximate the minimum inhibitory concentration for susceptible organisms (0.5 μg/ml).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2004 journal article
Pharmacokinetics and pharmacodynamics of furosemide after oral administration to horses
JOURNAL OF VETERINARY INTERNAL MEDICINE, 18(5), 739–743.
author keywords: equine; frusemide; loop diuretic; oral bioavailability
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2004 journal article
Pharmacokinetic disposition of a long-acting oxytetracycline formulation after single-dose intravenous and intramuscular administrations in the American alligator (Alligator mississippiensis)
JOURNAL OF ZOO AND WILDLIFE MEDICINE, 35(3), 341–346.
author keywords: American alligator; Alligator mississippiensis; pharmacokinetics; long-acting oxytetracycline; parenteral; antibiotic
MeSH headings : Alligators and Crocodiles / blood; Alligators and Crocodiles / metabolism; Animals; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Area Under Curve; Injections, Intramuscular / veterinary; Injections, Intravenous / veterinary; Metabolic Clearance Rate; Oxytetracycline / administration & dosage; Oxytetracycline / blood; Oxytetracycline / pharmacokinetics
TL;DR:
Based on the results of this study, long-acting preparations of oxytetracycline administered parenterally to American alligators at 10 mg/kg q 5 days is expected to maintain plasma concentrations above the minimum inhibitory concentration of 4.0 μg/ml for susceptible organisms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2004 journal article
Oral immunization with recombinant Listeria monocytogenes controls virus load after vaginal challenge with feline immunodeficiency virus
JOURNAL OF VIROLOGY, 78(15), 8210–8218.
MeSH headings : Administration, Oral; Animals; Antibodies, Viral / biosynthesis; Cats; Feline Acquired Immunodeficiency Syndrome / prevention & control; Feline Acquired Immunodeficiency Syndrome / virology; Female; Gene Products, gag / genetics; Gene Products, gag / immunology; Immunization; Immunodeficiency Virus, Feline / isolation & purification; Immunoglobulin A / biosynthesis; Immunoglobulin G / biosynthesis; Intestinal Mucosa / immunology; Listeria monocytogenes / genetics; Lymph Nodes / immunology; Lymphocyte Depletion; Proviruses / isolation & purification; Vaccines, Synthetic / immunology; Viral Load; Viral Vaccines / immunology
TL;DR:
It is demonstrated that recombinant L. monocytogenes conferred some control of viral load after vaginal challenge with FIV, using the feline immunodeficiency virus (FIV) model of HIV.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2004 journal article
Nitric oxide synthase stimulates prostaglandin synthesis and barrier function in C-parvum-infected porcine ileum
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 287(3), G571–G581.
author keywords: Cryptosporidium parvum; permeability
MeSH headings : Animals; Animals, Newborn; Atrophy; Cryptosporidiosis / enzymology; Cryptosporidiosis / physiopathology; Cryptosporidium parvum; Diarrhea / microbiology; Diarrhea / pathology; Dinoprostone / biosynthesis; Eicosanoids / biosynthesis; Epoprostenol / biosynthesis; Ileum / physiopathology; Intestinal Mucosa / metabolism; Microscopy, Electron; Nitric Oxide Synthase / genetics; Nitric Oxide Synthase / physiology; Nitric Oxide Synthase Type II; Prostaglandins / biosynthesis; Reverse Transcriptase Polymerase Chain Reaction; Sodium / metabolism; Swine; Thromboxane A2 / biosynthesis
TL;DR:
Using an entire intestinal mucosa, it is demonstrated for the first time that NO serves as a proximal mediator of PGE2 synthesis and barrier function in C. parvum infection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2004 article
Doppler ultrasonographic evaluation of gastrointestinal hemodynamics in food hypersensitivities: A canine model
JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 18, pp. 605–611.
author keywords: celiac artery; cranial mesenteric artery; dietary challenge; splanchnic blood flow
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2004 journal article
Chemotherapy followed by half-body radiation therapy for canine lymphoma
JOURNAL OF VETERINARY INTERNAL MEDICINE, 18(5), 703–709.
author keywords: cancer; dog; multimodality therapy
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2004 journal article
Assessment of CD4+ and CD8+ IFN-gamma producing cells by ELISPOT in naive and FIV-infected cats
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 102(1-2), 77–84.
author keywords: feline immunodeficiency virus; ELISPOT; CD4+; CD8+; T-cell subsets
MeSH headings : Animals; CD4-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / immunology; Cats; Concanavalin A / immunology; Feline Acquired Immunodeficiency Syndrome / blood; Feline Acquired Immunodeficiency Syndrome / immunology; Immunodeficiency Virus, Feline / immunology; Immunoenzyme Techniques / veterinary; Interferon-gamma / biosynthesis; Interferon-gamma / immunology; Lymphocyte Activation / immunology; Lymphocyte Count / veterinary
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2004 journal article
The infant mouse as a in vivo model for the detection and study of DNA damage-induced changes in the liver
MOLECULAR CARCINOGENESIS, 40(1), 62–72.
author keywords: p53 protein; cell cycle; hepatocyte
MeSH headings : Animals; Animals, Newborn; Antibiotics, Antineoplastic / pharmacology; Bleomycin / toxicity; Cell Cycle Proteins / metabolism; Cell Division; Chemokine CXCL1; Chemokines, CXC / metabolism; Cyclin G; Cyclin G1; Cyclin-Dependent Kinase Inhibitor p21; Cyclins / metabolism; DNA / drug effects; DNA / radiation effects; DNA Damage; Disease Models, Animal; Gamma Rays / adverse effects; Insulin-Like Growth Factor Binding Protein 1 / metabolism; Intercellular Signaling Peptides and Proteins / metabolism; Liver / metabolism; Mice; Mice, Inbred C57BL; Nuclear Proteins; Proto-Oncogene Proteins / metabolism; Proto-Oncogene Proteins c-mdm2; Tumor Suppressor Protein p53 / metabolism; Whole-Body Irradiation
TL;DR:
This work characterizes various parameters in the infant mouse, thus validating the use of this model to study in vivo DNA damage–induced cell‐cycle–related changes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2004 journal article
Sp2 DNA binding activity and trans-activation are negatively regulated in mammalian cells
JOURNAL OF BIOLOGICAL CHEMISTRY, 279(14), 13911–13924.
MeSH headings : Animals; Base Sequence; COS Cells; Consensus Sequence; Cricetinae; DNA-Binding Proteins / chemistry; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; Epithelial Cells / cytology; Epithelial Cells / physiology; Humans; Male; Mammals; Mice; Promoter Regions, Genetic / physiology; Prostate / cytology; Prostate-Specific Antigen / genetics; Protein Structure, Tertiary; Recombinant Fusion Proteins / genetics; Recombinant Fusion Proteins / metabolism; Sp1 Transcription Factor / chemistry; Sp1 Transcription Factor / genetics; Sp1 Transcription Factor / metabolism; Sp2 Transcription Factor; Sp3 Transcription Factor; Tetrahydrofolate Dehydrogenase / genetics; Transcription Factors / chemistry; Transcription Factors / genetics; Transcription Factors / metabolism; Transcription, Genetic / physiology
TL;DR:
Sp2 is functionally distinct relative to other Sp family members and suggest that Sp2 may play a unique role in cell physiology, using chimeric molecules prepared with portions of Sp1 and Sp2 and the human prostate-specific antigen promoter.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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