Works Published in 2016
Displaying works 101 - 117 of 117 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2016 journal article
Navigational ultrasound imaging: A novel imaging tool for aiding interventional therapies of equine musculoskeletal injuries
EQUINE VETERINARY JOURNAL, 48(2), 195–200.
author keywords: horse; navigational ultrasound imaging; fusion imaging; musculoskeletal; MRI
MeSH headings : Animals; Forelimb; Hindlimb; Horse Diseases / diagnosis; Horse Diseases / diagnostic imaging; Horse Diseases / surgery; Horses; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging / veterinary; Musculoskeletal Diseases / diagnostic imaging; Musculoskeletal Diseases / pathology; Musculoskeletal Diseases / surgery; Musculoskeletal Diseases / veterinary; Tomography, X-Ray Computed / veterinary; Ultrasonography
TL;DR:
Navigational ultrasound imaging is a complementary imaging modality that can be used for the treatment of equine soft tissue musculoskeletal injuries diagnosed with MRI and is considered successful based on the authors' criteria.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Carprofen pharmacokinetics in plasma and in control and inflamed canine tissue fluid using in vivo ultrafiltration
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 39(1), 32–39.
MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / blood; Anti-Inflammatory Agents, Non-Steroidal / metabolism; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Area Under Curve; Body Fluids / chemistry; Carbazoles / blood; Carbazoles / metabolism; Carbazoles / pharmacokinetics; Carrageenan / toxicity; Dinoprostone / metabolism; Dog Diseases / blood; Dog Diseases / chemically induced; Dog Diseases / metabolism; Dogs; Half-Life; Inflammation / chemically induced; Inflammation / metabolism; Inflammation / veterinary; Ultrafiltration / veterinary
TL;DR:
In vivo ultrafiltration is a reliable method to determine unbound carprofen in ISF, and that disposition of unbound drug into tissue is much higher than predicted from un bound drug concentration in plasma, however, concentrations and pharmacokinetic parameter estimates are not significantly different in inflamed vs. un-inflamed tissues.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
Alternate-day dosing of itraconazole in healthy adult cats
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 39(1), 27–31.
MeSH headings : Animals; Antifungal Agents / administration & dosage; Antifungal Agents / blood; Antifungal Agents / pharmacokinetics; Cats / blood; Drug Administration Schedule; Half-Life; Itraconazole / administration & dosage; Itraconazole / blood; Itraconazole / pharmacokinetics
TL;DR:
Overall, a 100 mg every other day oral dosage regimen for itraconazole in cats yielded serum concentrations with minimal fluctuation and with careful monitoring may be considered for treatment of cats with systemic fungal disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
Structural perturbation of a dipalmitoylphosphatidylcholine (DPPC) bilayer by warfarin and its bolaamphiphilic analogue: A molecular dynamics study
JOURNAL OF COLLOID AND INTERFACE SCIENCE, 468, 227–237.
Contributors: M. Ayee*, C. Roth* & B. Akpa n
author keywords: Bolaamphiphile; Bilayer; Anticoagulant; Toxicity; Permeation; Phospholipid; Warfarin; Brodifacoum; Defect; Hydroxycoumarin
MeSH headings : 1,2-Dipalmitoylphosphatidylcholine / chemistry; Lipid Bilayers / chemistry; Molecular Dynamics Simulation; Molecular Structure; Surface-Active Agents / chemistry; Warfarin / chemistry
TL;DR:
The consequences of anticoagulant accumulation in a dipalmitoylphosphatidylcholine bilayer are explored and it is found that brodifacoum partitioning into bilayers causes membrane thinning and permeabilization and promotes lipid flip-flop - phenomena that are suspected to play a role in triggering cell death.
(via Semantic Scholar)
manuscript.elsevier.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2016 journal article
Histamine H4 receptor knockout mice display reduced inflammation in a chronic model of atopic dermatitis
ALLERGY, 71(2), 189–197.
author keywords: Allergic inflammation; atopic dermatitis; histamine H4 receptor; OVA
MeSH headings : Animals; CD4-Positive T-Lymphocytes / immunology; CD4-Positive T-Lymphocytes / metabolism; Cytokines / biosynthesis; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / etiology; Dermatitis, Atopic / metabolism; Dermatitis, Atopic / pathology; Disease Models, Animal; Epidermis / immunology; Epidermis / metabolism; Epidermis / pathology; Female; Immunoglobulin E / immunology; Lymph Nodes / immunology; Lymph Nodes / metabolism; Mice; Mice, Knockout; Ovalbumin / adverse effects; Piperidines / pharmacology; Pyridines / pharmacology; Receptors, G-Protein-Coupled / antagonists & inhibitors; Receptors, G-Protein-Coupled / deficiency; Receptors, G-Protein-Coupled / genetics; Receptors, Histamine / deficiency; Receptors, Histamine / genetics; Receptors, Histamine H4; Skin / immunology; Skin / metabolism; Skin / pathology
TL;DR:
The histamine H4 receptor (H4R) was brought into focus as a new therapeutic target for the treatment of allergic disorders such as atopic dermatitis (AD).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Factors associated with tick bites and pathogen prevalence in ticks parasitizing humans in Georgia, USA
Parasites & Vectors, 9.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Exuberant granulation tissue response associated with Neobenedenia sp (Monogenea: Capsalidae) infestation in two cobia, Rachycentron canadum (Linnaeus)
JOURNAL OF FISH DISEASES, 39(3), 277–283.
author keywords: granulation tissue; Neobenedenia; Rachycentron canadum
MeSH headings : Animals; Animals, Zoo / parasitology; Fish Diseases / parasitology; Gills / parasitology; Granulation Tissue / parasitology; Perciformes / parasitology; Trematoda / physiology; Trematode Infections / parasitology; Trematode Infections / veterinary
TL;DR:
An unusual pathological presentation of exuberant granulation tissue of the gills, suspected to be related to Neobenedenia infestation in two cobia housed together at a North Carolina aquarium is described.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Expression of WNT5A in idiopathic pulmonary fibrosis and its control by TGF-beta and WNT7B in human lung fibroblasts
Journal of Histochemistry and Cytochemistry, 64(2), 99–111.
MeSH headings : Cells, Cultured; Fibroblasts / metabolism; Fibroblasts / pathology; Gene Expression Regulation; Gene Silencing; Humans; Idiopathic Pulmonary Fibrosis / genetics; Idiopathic Pulmonary Fibrosis / metabolism; Idiopathic Pulmonary Fibrosis / pathology; Lung / metabolism; Lung / pathology; Myocytes, Smooth Muscle / metabolism; Myofibroblasts / metabolism; Myofibroblasts / pathology; Proto-Oncogene Proteins / analysis; Proto-Oncogene Proteins / genetics; Proto-Oncogene Proteins / metabolism; Transforming Growth Factor beta / analysis; Transforming Growth Factor beta / genetics; Transforming Growth Factor beta / metabolism; Up-Regulation; Wnt Proteins / analysis; Wnt Proteins / genetics; Wnt Proteins / metabolism; Wnt-5a Protein
TL;DR:
A wide distribution of Wnt5A expression in cells of the IPF lung is demonstrated and it is revealed that it is significantly increased by Wnt7B and TGF-β1, which, in combination, could represent key signaling pathways that modulate the pathogenesis of IPF.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons
Nature Genetics, 48(4), 427–437.
MeSH headings : Animals; Evolution, Molecular; Female; Fishes / genetics; Fishes / metabolism; Genome; Humans; Karyotype; Models, Genetic; Organ Specificity; Sequence Analysis, DNA; Transcriptome
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: NC State University Libraries, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2016 journal article
The mitochondrial landscape of African Americans: An examination of more than 2500 control region haplotypes from 22 US locations
FORENSIC SCIENCE INTERNATIONAL-GENETICS, 22, 139–148.
author keywords: Mitochondrial DNA; Control region; African American
MeSH headings : Black or African American / genetics; DNA, Mitochondrial / genetics; Databases, Genetic; Forensic Genetics / methods; Genetic Variation; Genetics, Population; Haplotypes; Humans; Mitochondria / genetics; United States
TL;DR:
The mitochondrial DNA control region was Sanger-sequenced for a total of 2563 self-identified African Americans, using automated processing techniques and data review standards exceeding guidelines for forensic applications and are suitable for use in a forensic mtDNA database.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Sequence variation of 22 autosomal STR loci detected by next generation sequencing
Forensic Science International-Genetics, 21, 15–21.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Mechanisms of Tritrichomonas foetus Pathogenicity in Cats with Insights from Venereal Trichomonosis
Journal of Veterinary Internal Medicine, 30(2), 516–526.
author keywords: Diarrhea; Protozoa; Trichomonas; Trichomonas vaginalis
MeSH headings : Animals; Cat Diseases / parasitology; Cat Diseases / pathology; Cats; Protozoan Infections, Animal / parasitology; Protozoan Infections, Animal / pathology; Sexually Transmitted Diseases / parasitology; Sexually Transmitted Diseases / pathology; Sexually Transmitted Diseases / veterinary; Tritrichomonas foetus
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2016 review
Frogs as integrative models for understanding digestive organ development and evolution
[Review of ]. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 51, 92–105.
author keywords: Embryo; Xenopus; Lepidobatrachus; Eleutherodactylous coqui; Gut; Specification; Morphogenesis; Evolution
MeSH headings : Animals; Biological Evolution; Calcium Signaling; Cell Communication; Digestive System / cytology; Digestive System / embryology; Endoderm / cytology; Endoderm / embryology; Gene Expression; Gene Expression Regulation, Developmental; Humans; Morphogenesis; Xenopus Proteins / genetics; Xenopus Proteins / metabolism; Xenopus laevis / embryology
TL;DR:
The unparalleled experimental versatility of frog embryos make them excellent, integrative models for studying digestive organ development across multiple disciplines, including the regeneration or replacement of diseased organs, the etiology of digestive organ birth defects, and the evolution of specialized features of digestive anatomy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Evaluation of a DLA-79 allele associated with multiple immune-mediated diseases in dogs
IMMUNOGENETICS, 68(3), 205–217.
author keywords: Canine; Immune-mediated disease; Dog leukocyte antigen; Major histocompatibility complex class Ib
MeSH headings : Alleles; Amino Acid Substitution; Animals; Autoimmune Diseases / genetics; Autoimmune Diseases / immunology; Binding Sites; Dog Diseases / genetics; Dog Diseases / immunology; Dogs; Exons; Gene Frequency; Genetic Predisposition to Disease; Genotype; Histocompatibility Antigens Class I / chemistry; Histocompatibility Antigens Class I / genetics; Histocompatibility Antigens Class I / immunology; Immune System Diseases / veterinary; Meta-Analysis as Topic; Models, Molecular; Peptides / chemistry; Peptides / metabolism; Phenotype; Polymorphism, Single Nucleotide; Protein Conformation; Reproducibility of Results; Structure-Activity Relationship
TL;DR:
A strong association is demonstrated between two polymorphic positions (10 bp apart) in exon 2 of one allele in D LA-79, DLA-79*001:02, and multiple immune-mediated diseases, resulting in F33L and N37D amino acid changes that are likely to affect critical interactions with the peptide N-terminus.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Best practice recommendations for prehospital veterinary care of dogs and cats
JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 26(2), 166–233.
author keywords: cat; dog; first response; trauma; VetCOT
MeSH headings : Animals; Cats; Consensus; Databases, Factual; Dogs; Emergency Service, Hospital / standards; Practice Guidelines as Topic; Practice Management, Veterinary / standards; United States; Veterinary Medicine / standards; Wounds and Injuries / therapy; Wounds and Injuries / veterinary
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Neurotypic cell attachment and growth on III-nitride lateral polarity structures
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 58, 1194–1198.
author keywords: Gallium nitride; Cell adhesion; Neurons; Semiconductor; Polarity
MeSH headings : Aluminum Compounds / chemistry; Aluminum Compounds / pharmacology; Animals; Cell Adhesion / drug effects; Cell Differentiation / drug effects; Gallium / chemistry; Gallium / pharmacology; Neurons / cytology; Neurons / drug effects; PC12 Cells; Rats; Semiconductors
TL;DR:
The designed material configuration is further explored for biochemical sensing, and the lateral polarity scheme may provide a route in assessing the non-specific protein adsorption to this varying nano-topography that drives the subsequent cell response.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2016 article
Development of an Allergen-induced Atopic Itch Model in Dogs: A Preliminary Report
ACTA DERMATO-VENEREOLOGICA, Vol. 96, pp. 400–401.
MeSH headings : Animals; Anti-Allergic Agents / pharmacology; Antigens, Dermatophagoides; Behavior, Animal; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / immunology; Dermatitis, Atopic / psychology; Disease Models, Animal; Dogs; Glucocorticoids / pharmacology; Motor Activity; Prednisolone / pharmacology; Pruritus / drug therapy; Pruritus / immunology; Pruritus / psychology; Reproducibility of Results; Time Factors
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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