Works Published in 2020
Displaying works 121 - 140 of 216 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2020 journal article
Environmental Context Prediction for Lower Limb Prostheses With Uncertainty Quantification
IEEE Transactions on Automation Science and Engineering.
author keywords: Uncertainty; Neural networks; Bayes methods; Measurement uncertainty; Cameras; Microsoft Windows; Bayesian neural network (BNN); environmental context prediction; prosthesis; uncertainty quantification
TL;DR:
A novel vision-based context prediction framework for lower limb prostheses to simultaneously predict human’s environmental context for multiple forecast windows by leveraging the Bayesian neural networks (BNNs) and producing a calibrated predicted probability for online decision-making.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: July 28, 2020
2020 journal article
An Easy-to-Use Socket-Suspension System Monitor for Lower Limb Amputees
IEEE Transactions on Instrumentation and Measurement, 69(11), 8973–8982.
Contributors: M. Liu, D. Kamper n & H. Huang n
author keywords: Sockets; Monitoring; Magnetic field measurement; Magnetic sensors; Biomedical monitoring; Prosthetics; Biomedical monitoring; displacement measurement; magnetic sensors; prosthetics; wearable sensors
TL;DR:
A wearable SSS monitor that can be adopted for any SSS using liners without requiring permanent modifications of the SSS is designed and demonstrated the capability of tracking SSS fit changes during locomotion without permanent modification ofThe SSS.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: July 28, 2020
2020 journal article
Reliable Vision-Based Grasping Target Recognition for Upper Limb Prostheses
IEEE Transactions on Cybernetics.
author keywords: Grasping; Uncertainty; Prosthetics; Task analysis; Target recognition; Bayes methods; Prediction algorithms; Bayesian deep learning (BDL); grasping strategy; reliable computer vision; upper limb prosthesis
MeSH headings : Arm; Artificial Limbs; Bayes Theorem; Hand Strength; Humans; Robotics; Upper Extremity
TL;DR:
A novel, reliable vision-based framework to assist upper limb prosthesis grasping during arm reaching using Bayesian deep learning (BDL) and a probability calibration network was developed to fuse the uncertainty measures into one calibrated probability for online decision making.
(via Semantic Scholar)
Source: ORCID
Added: July 28, 2020
2020 journal article
Targeted Delivery of Notch Inhibitor Attenuates Obesity-Induced Glucose Intolerance and Liver Fibrosis
ACS NANO, 14(6), 6878–6886.
author keywords: drug delivery; nanomedicine; Notch inhibitor; nonalcoholic steatohepatitis; obesity; liver fibrosis
MeSH headings : Animals; Diabetes Mellitus, Type 2 / pathology; Disease Models, Animal; Glucose Intolerance / drug therapy; Glucose Intolerance / pathology; Liver / pathology; Liver Cirrhosis / drug therapy; Liver Cirrhosis / pathology; Mice; Obesity / drug therapy
TL;DR:
A nanoparticle-mediated delivery system to target γ-secretase inhibitor to liver (GSI NPs) reduces hepatic glucose production in diet-induced obese mice and reduced hepatic fibrosis and inflammation in mice fed a NASH-provoking diet, without apparent gastrointestinal toxicity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: July 20, 2020
2020 journal article
EXAMINING THE INFLUENCE OF LOW-DOSE TISSUE PLASMINOGEN ACTIVATOR ON MICROBUBBLE-MEDIATED FORWARD-VIEWING INTRAVASCULAR SONOTHROMBOLYSIS
ULTRASOUND IN MEDICINE AND BIOLOGY, 46(7), 1698–1706.
author keywords: Sonothrombolysis; Intravascular sonothrombolysis; Microbubble-mediated sonothrombolysis; Clot lysis; Tissue plasminogen activator
MeSH headings : Animals; Cattle; Combined Modality Therapy; Mechanical Thrombolysis / methods; Microbubbles / therapeutic use; Thrombolytic Therapy / methods; Thrombosis / drug therapy; Thrombosis / therapy; Tissue Plasminogen Activator / administration & dosage; Tissue Plasminogen Activator / therapeutic use; Ultrasonic Therapy / methods
TL;DR:
Changes in stable and inertial cavitation doses were observed, corresponding to changes in clot lysis in MB-mediated FVI sonothrombolysis with and without tPA.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: July 20, 2020
2020 journal article
The effects of knee extensor moment biofeedback on gait biomechanics and quadriceps contractile behavior
PEERJ, 8.
author keywords: Walking; Osteoarthritis; Joint loading; Rehabilitation; Gait training; Ultrasound; Biofeedback
TL;DR:
Targeted pKEM biofeedback may be a useful rehabilitative and/or scientific tool to elicit desirable changes in knee joint biomechanics considered relevant to the development of osteoarthritis.
(via Semantic Scholar)
peerj.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: July 20, 2020
2020 review
Alteration of Electron Acceptor Preferences in the Oxidative Half-Reaction of Flavin-Dependent Oxidases and Dehydrogenases
[Review of ]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21(11).
author keywords: oxidase; dehydrogenase; oxidative half-reaction; oxygen; electron acceptor; flavin adenine dinucleotide; flavin mononucleotide; oxygen accessible pathway; bioelectrochemistry; enzyme engineering
MeSH headings : Animals; Electron Transport; Flavins / chemistry; Flavins / metabolism; Flavoproteins / chemistry; Flavoproteins / metabolism; Humans; Oxidoreductases / chemistry; Oxidoreductases / metabolism; Oxygen / chemistry; Oxygen / metabolism
TL;DR:
In this review, recent progress in the engineering of the oxidative half-reaction of flavin-dependent oxidases and dehydrogenases is discussed, considering their current and future applications in bioelectrochemical studies, such as for the development of biosensors and biofuel cells.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: July 20, 2020
2020 journal article
Impact of elastic ankle exoskeleton stiffness on neuromechanics and energetics of human walking across multiple speeds
JOURNAL OF NEUROENGINEERING AND REHABILITATION, 17(1).
author keywords: Locomotion; Wearable robotics; Plantarflexors; Spring-loaded; Lower-limb joints; Biomechanics; Metabolic cost; Compliant
MeSH headings : Adult; Ankle Joint / physiology; Biomechanical Phenomena / physiology; Energy Metabolism / physiology; Exoskeleton Device; Female; Humans; Male; Muscle, Skeletal / physiology; Walking / physiology
TL;DR:
The relationship between the non-weighted sum of soleus and tibialis activation rate and metabolic cost indicates that muscle activation may drive metabolic demand in exoskeleton systems, and elastic ankle exoskeletons with low rotational stiffness reduce users’ metabolic cost at slow and fast but not intermediate walking speed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: July 13, 2020
2020 journal article
Utilizing multi-user virtual reality to bring clinical therapy into stroke survivors' homes
JOURNAL OF HAND THERAPY, 33(2), 246–253.
author keywords: Therapy; Stroke; Home-based training; Virtual reality
TL;DR:
Multiuser virtual reality offers a relatively inexpensive means of extending clinical therapy into home and enabling family and friends to support rehabilitation efforts, even when physically remote from each other.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: July 13, 2020
2020 journal article
Electro-thermal therapy: Microsecond duration pulsed electric field tissue ablation with dynamic temperature control algorithms
COMPUTERS IN BIOLOGY AND MEDICINE, 121.
author keywords: Cancer therapy; Irreversible electroporation; Thermal ablation; H-FIRE; NK-IRE
MeSH headings : Algorithms; Electrodes; Electroporation; Liver / surgery; Temperature
TL;DR:
The results establish ETT as a viable method for hepatic tumor treatment with ablation profiles equivalent to other energy based techniques and the single applicator and multi-applicator approaches demonstrated may enable the treatment of complex tumor geometries.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
7. Affordable and Clean Energy
(OpenAlex)
Source: Web Of Science
Added: July 13, 2020
2020 journal article
Survivors of Chronic Stroke Experience Continued Impairment of Dexterity But Not Strength in the Nonparetic Upper Limb
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION, 101(7), 1170–1175.
author keywords: Functional laterality; Recovery of function; Rehabilitation; Stroke; Stroke rehabilitation
MeSH headings : Academic Medical Centers; Aged; Chronic Disease; Cohort Studies; Cross-Sectional Studies; Disability Evaluation; Exercise Test / methods; Female; Hand Strength / physiology; Humans; Male; Middle Aged; Paresis / rehabilitation; Prognosis; Reference Values; Rehabilitation Centers; Risk Assessment; Stroke / diagnosis; Stroke / therapy; Stroke Rehabilitation / methods; Survivors; Treatment Outcome; Upper Extremity / physiopathology
TL;DR:
The results suggest that the nonparetic upper limb should be targeted for rehabilitation in stroke survivors with severe impairment of the paretic limb, as they continue to present significant upper extremity impairment in their nominally nonperetic limb even years after stroke.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
4. Quality Education
(OpenAlex)
Source: Web Of Science
Added: July 13, 2020
2020 journal article
Increasing the Propulsive Demands of Walking to Their Maximum Elucidates Functionally Limiting Impairments in Older Adult Gait
JOURNAL OF AGING AND PHYSICAL ACTIVITY, 28(1), 1–8.
author keywords: ankle moment; biomechanics; impeding forces; push-off
MeSH headings : Aged; Aging; Ankle Joint; Biomechanical Phenomena; Gait; Humans; Walking; Walking Speed; Young Adult
TL;DR:
It was found that older adults walked at their preferred speed with hallmark deficits in push-off intensity, and age-related deficits in ankle moment emerged as the lone genuine functionally limiting impairment in older adults.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: July 6, 2020
2020 journal article
Biomechanical effects of manipulating peak vertical ground reaction force throughout gait in individuals 6-12 months after anterior cruciate ligament reconstruction
CLINICAL BIOMECHANICS, 76.
author keywords: Knee; Biofeedback; Gait-training; Unloading
MeSH headings : Adult; Anterior Cruciate Ligament Injuries / physiopathology; Anterior Cruciate Ligament Injuries / surgery; Anterior Cruciate Ligament Reconstruction; Biomechanical Phenomena; Female; Gait / physiology; Humans; Male; Mechanical Phenomena
TL;DR:
Cueing a 5% body weight increase in vertical ground reaction force impact peak resulted in a more dynamic vertical ground reacted force loading pattern, increased knee excursion, and a greater internal extension moment during stance which may be useful in restoring gait patterns following anterior cruciate ligament reconstruction.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: June 29, 2020
2020 journal article
Rational engineering of Aerococcus viridans L-lactate oxidase for the mediator modification to achieve quasi-direct electron transfer type lactate sensor
BIOSENSORS & BIOELECTRONICS, 151.
author keywords: L-lactate oxidase; Amine reactive phenazine ethosulfate; Site-directed mutagenesis; Amperometric L-lactate biosensor; Interference; Direct electron transfer
MeSH headings : Aerococcus / chemistry; Aerococcus / isolation & purification; Biosensing Techniques; Catalysis; Enzymes, Immobilized / chemistry; Glucose / chemistry; Humans; Lactic Acid / chemistry; Lactic Acid / isolation & purification; Mixed Function Oxygenases / chemistry; Oxidation-Reduction
TL;DR:
Results indicated that a quasi-DET type lactate sensor was developed that did not suffer from the interference of oxygen and representative electroactive ingredient compounds.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: June 29, 2020
2020 journal article
Scaffold-Mediated Static Transduction of T Cells for CAR-T Cell Therapy
ADVANCED HEALTHCARE MATERIALS, 9(14).
author keywords: alginate scaffold; CAR-T cells; cell therapy; immunotherapy; viral transduction
MeSH headings : Antigens, CD19; Cell- and Tissue-Based Therapy; Humans; Immunotherapy, Adoptive; Receptors, Chimeric Antigen / genetics; T-Lymphocytes
TL;DR:
The data show that macroporous alginate scaffolds serve as an attractive alternative to current transduction protocols and have high potential for clinical translation to genetically modify T cells for adoptive cellular therapy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: June 29, 2020
2020 review
Nanostructured Medical Adhesives
[Review of ]. JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, 16(3), 263–282.
author keywords: Adhesive; Laser; Tissue Closure; Photothermal; Photochemical; Nanoparticle; Microbarb; Glue; Tape
MeSH headings : Adhesives; Extracellular Matrix; Lasers; Nanoparticles; Tissue Adhesives
TL;DR:
The capability for rapid attachment and release may further reduce surgical procedure time and the novel tissue joining methods aim to provide an adhesive with appropriate strength, non-cytotoxicity, and minimal damage.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 29, 2020
2020 journal article
Elicited upper limb motions through transcutaneous cervical spinal cord stimulation
JOURNAL OF NEURAL ENGINEERING, 17(3).
author keywords: transcutaneous electrical stimulation; spinal cord stimulation; upper extremity kinematics; arm function; hand function
MeSH headings : Hand; Humans; Muscle, Skeletal; Range of Motion, Articular; Spinal Cord; Spinal Cord Stimulation; Upper Extremity
TL;DR:
The results revealed that distal and proximal joint movements can be elicited either independently or synergistically, and the feasibility of the spinal cord stimulation technique in eliciting functional movements of the upper limb was demonstrated.
(via Semantic Scholar)
Source: Web Of Science
Added: June 29, 2020
2020 journal article
Vitamin D Receptor Activation and Photodynamic Priming Enables Durable Low-dose Chemotherapy
MOLECULAR CANCER THERAPEUTICS, 19(6), 1308–1319.
MeSH headings : Animals; Antineoplastic Agents / pharmacology; Apoptosis; Biomarkers, Tumor / genetics; Biomarkers, Tumor / metabolism; Calcitriol / analogs & derivatives; Calcitriol / pharmacology; Carcinoma, Pancreatic Ductal / drug therapy; Carcinoma, Pancreatic Ductal / metabolism; Carcinoma, Pancreatic Ductal / pathology; Carcinoma, Pancreatic Ductal / radiotherapy; Cell Proliferation; Chemokine CXCL12 / genetics; Chemokine CXCL12 / metabolism; Dermatologic Agents / pharmacology; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Nude; Pancreatic Neoplasms / drug therapy; Pancreatic Neoplasms / metabolism; Pancreatic Neoplasms / pathology; Pancreatic Neoplasms / radiotherapy; Photochemotherapy; Receptors, CXCR / genetics; Receptors, CXCR / metabolism; Receptors, CXCR4 / genetics; Receptors, CXCR4 / metabolism; Receptors, Calcitriol / genetics; Receptors, Calcitriol / metabolism; Tumor Cells, Cultured; Xenograft Model Antitumor Assays
TL;DR:
A dual pronged approach to modulate the microenvironment of desmoplastic pancreatic tumors and enable significant dose deescalation of the FDA-approved chemotherapeutic nanoliposomal irinotecan (nal-IRI) without compromising tumor control is introduced.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 22, 2020
2020 journal article
CRISPR-Cas12a delivery by DNA-mediated bioresponsive editing for cholesterol regulation
SCIENCE ADVANCES, 6(21).
MeSH headings : CRISPR-Cas Systems; Cholesterol; DNA / genetics; DNA / metabolism; Gene Editing; Polymers / metabolism; Proprotein Convertase 9 / genetics; Proprotein Convertase 9 / metabolism; RNA / genetics; Ribonucleoproteins / genetics
TL;DR:
A DNA nanoclew (NC)-based carrier for delivery of Cas12a/CRISPR RNA (crRNA) ribonucleoprotein (R NP) toward regulating serum cholesterol levels and significantly reducing the expression of PCSK9 and gaining the therapeutic benefit of cholesterol control.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 22, 2020
2020 journal article
Scalable Formation of Concentrated Monodisperse Lignin Nanoparticles by Recirculation-Enhanced Flash Nanoprecipitation
PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION, 37(7).
author keywords: benign nanomaterials; flash nanoprecipitation; monodisperse lignin nanoparticles; scale-up
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: Web Of Science
Added: June 22, 2020
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