Works Published in 2008

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Displaying works 1 - 20 of 99 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2008 journal article

Impact of Deliquescence on the Chemical Stability of Vitamins B1, B6, and C in Powder Blends

Journal of Agricultural and Food Chemistry, 56(15), 6471–6479.

author keywords: deliquescence; thiamin; pyridoxine; ascorbate; stability; humidity
MeSH headings : Adsorption; Ascorbic Acid / chemistry; Chromatography, High Pressure Liquid; Drug Stability; Humidity; Hydrogen-Ion Concentration; Pharmaceutical Preparations / chemistry; Powders / chemistry; Thiamine / chemistry; Vitamin B 6 / chemistry; Water / analysis
TL;DR: Formulation, storage conditions, and the relation of these to deliquescence points may affect the shelf life, quality, and functionality of vitamin blends and should be considered in product development, processing, storage, and use. (via Semantic Scholar)
Source: Crossref
Added: January 24, 2021

2008 journal article

ADSA® Presidential Report

Journal of Dairy Science, 91(12), 4892–4894.

By: M. Drake*

Source: Crossref
Added: January 14, 2021

2008 journal article

Comparison of PCR-DGGE and Selective Plating Methods for Monitoring the Dynamics of a Mixed Culture Population in Synthetic Brewery Wastewater

Biotechnology Progress, 21(3), 712–719.

By: K. Tam*, C. Yang*, M. Matsumoto*, D. Crowley* & J. Sheppard*

MeSH headings : Acinetobacter / isolation & purification; Acinetobacter / physiology; Bioreactors / microbiology; Candida / isolation & purification; Candida / physiology; Cell Culture Techniques / methods; Coculture Techniques / methods; Colony Count, Microbial / methods; Electrophoresis / methods; Enterobacter / isolation & purification; Enterobacter / physiology; Industrial Waste / analysis; Polymerase Chain Reaction / methods; Water Microbiology; Water Pollutants, Chemical / pharmacokinetics
TL;DR: PCR‐DGGE was effective for detecting the dominant species, but culture‐based methods were more accurate for monitoring the population dynamics of these microorganisms during growth in the wastewater medium. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Crossref
Added: December 21, 2020

2008 journal article

A Kinetic Model for Suspended and Attached Growth of a Defined Mixed Culture

Biotechnology Progress, 21(3), 720–727.

By: K. Tam*, M. Matsumoto* & J. Sheppard*

MeSH headings : Acinetobacter / physiology; Bacterial Adhesion / physiology; Bioreactors / microbiology; Candida / isolation & purification; Candida / physiology; Cell Culture Techniques / methods; Cell Proliferation; Coculture Techniques / methods; Computer Simulation; Enterobacter / physiology; Ethanol / metabolism; Glucose / metabolism; Industrial Waste / prevention & control; Maltose / metabolism; Models, Biological; Water Microbiology; Water Pollutants, Chemical / pharmacokinetics
TL;DR: Kinetic experiments were carried out in a semicontinuous wastewater treatment process called self‐cycling fermentation (SCF) using a defined mixed culture and various concentrations of synthetic brewery wastewater and indicated that substrate removal by the suspended cells was directly related to the biomass concentration. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Crossref
Added: December 21, 2020

2008 journal article

Isolation of Radiolabeled Isoflavones from Kudzu (Pueraria lobata) Root Cultures

Journal of Agricultural and Food Chemistry, 56(17), 7860–7865.

By: A. Reppert*, G. Yousef*, R. Rogers* & M. Lila*

author keywords: kudzu; Pueraria lobata; isoflavones; puerarin; daidzein
MeSH headings : Carbon Radioisotopes; Isoflavones / analysis; Isoflavones / isolation & purification; Isotope Labeling; Plant Roots / chemistry; Pueraria / chemistry; Tissue Culture Techniques
TL;DR: The isolated isoflavones isolated from kudzu root cultures were sufficiently (14)C-labeled to permit utilization for subsequent in vivo metabolic tracking studies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 9, 2020

2008 journal article

Optimization of Lycopene Extraction from Tomato Cell Suspension Culture by Response Surface Methodology

Journal of Agricultural and Food Chemistry, 56(17), 7710–7714.

By: C. Lu*, N. Engelmann*, M. Lila* & J. Erdman*

author keywords: tomato; cell culture; lycopene; extraction; RSM
MeSH headings : Carotenoids / analysis; Carotenoids / isolation & purification; Cell Culture Techniques; Chromatography, High Pressure Liquid; Ethanol; Fruit / chemistry; Fruit / cytology; Hydroxides; Lycopene; Solanum lycopersicum / chemistry; Organophosphates; Plant Extracts / chemistry; Potassium Compounds; Statistics as Topic
TL;DR: These optimal conditions predicted by RSM were confirmed to enhance lycopene yield from standardized tomato cell cultures by more than 3-fold. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 9, 2020

2008 journal article

Phytoecdysteroids Increase Protein Synthesis in Skeletal Muscle Cells

Journal of Agricultural and Food Chemistry, 56(10), 3532–3537.

By: J. Gorelick-Feldman*, D. MacLean*, N. Ilic*, A. Poulev*, M. Lila*, D. Cheng*, I. Raskin*

author keywords: ecdysteroid; ajuga; spinach; protein synthesis; skeletal muscle; myotube; C2C12
MeSH headings : Ajuga / chemistry; Animals; Cell Line; Ecdysteroids / analysis; Ecdysteroids / pharmacology; Ecdysterone / pharmacology; Humans; Male; Mice; Muscle Cells / drug effects; Muscle Cells / metabolism; Muscle Fibers, Skeletal / drug effects; Muscle Fibers, Skeletal / metabolism; Muscle, Skeletal / drug effects; Muscle, Skeletal / metabolism; Plants / chemistry; Protein Biosynthesis / drug effects; Rats; Rats, Sprague-Dawley; Spinacia oleracea / chemistry
TL;DR: An in vitro cellular assay of protein synthesis was developed and found that phytoecdysteroids increased protein synthesis by up to 20% and ecdysteroid-containing plant extracts produced similar results, which suggests a PI3K-mediated mechanism. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 9, 2020

2008 journal article

Influence of Alternative Liquid Chromatography Techniques on the Chemical Complexity and Bioactivity of Isolated Proanthocyanidin Mixtures

Journal of Agricultural and Food Chemistry, 56(6), 1896–1906.

author keywords: proanthocyanidins; wild blueberry; Vaccinium angustifolium Ait.; Toyopearl HW-40; sephadex; LH-20; silica gel type G; topolsomerase II bioassay
MeSH headings : Chromatography, High Pressure Liquid; Chromatography, Liquid / methods; Enzyme Inhibitors / pharmacology; Humans; Plant Extracts / chemistry; Plant Extracts / pharmacology; Proanthocyanidins / chemistry; Proanthocyanidins / isolation & purification; Spectrometry, Mass, Electrospray Ionization; Topoisomerase II Inhibitors
TL;DR: A 2(3) factorial analysis revealed that the vacuum and open column strategies for separation did not yield significantly different results in terms of mass recovery, DP, or bioactivity; however, interactions with other factors such as matrix or subfraction series resulted in distinctive shifts in fraction profiles and biological activity. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 9, 2020

2008 journal article

Phytochemical Composition and Metabolic Performance-Enhancing Activity of Dietary Berries Traditionally Used by Native North Americans

Journal of Agricultural and Food Chemistry, 56(3), 654–660.

By: T. Burns Kraft, M. Dey, R. Rogers, D. Ribnicky, D. Gipp, W. Cefalu, I. Raskin, M. Lila*

author keywords: Amelanchier alnifolia; Viburnum trilobum; Prunus virginiana; Shepherdia argentea; diabetes; inflammation; energy expenditure
MeSH headings : Aldehyde Reductase / antagonists & inhibitors; Anthocyanins / analysis; Diet; Elaeagnaceae / chemistry; Energy Metabolism / drug effects; Flavonoids / analysis; Fruit / chemistry; Humans; Indians, North American; Plant Extracts / chemistry; Prunus / chemistry; Rosaceae / chemistry; Viburnum / chemistry
TL;DR: Four wild berry species integral to the traditional subsistence diet of Native American tribal communities contain a rich array of phytochemicals that have the capacity to promote health and protect against chronic diseases, such as diabetes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 9, 2020

2008 journal article

Neo-clerodane diterpenes from Ajuga turkestanica

Phytochemistry Letters, 1(2), 81–84.

By: M. Grace*, D. Cheng*, I. Raskin* & M. Lila*

author keywords: Ajuga turkestanica; Labiatae; Neo-clerodane diterpenes; 14,15-Dihydroajugachin B; 14-Hydro-15-methoxyajugachin B
TL;DR: The ethyl acetate extract of the aerial parts of Ajuga turkestanica afforded 6 neo-clerodane diterpenes, including two novel compounds, 14, 15-dihydroajugachin B and 14-hydro-15-methoxyajugaches B and chamaepitin, which were elucidated through exhaustive NMR spectroscopic analysis and chemical transformation. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 9, 2020

2008 journal article

Satiety in rats following blueberry extract consumption induced by appetite-suppressing mechanisms unrelated to in vitro or in vivo antioxidant capacity

Food Chemistry, 107(3), 1039–1044.

By: A. Molan*, M. Lila* & J. Mawson*

author keywords: blueberry; cultivars; satiety; rats; antioxidant; FRAP
TL;DR: The observed results suggest that the reduction in food intake and decrease in body weight in experimental animals is not merely a consequence of antioxidant mechanisms, and BBE may provide a good satiety inducer and weight management modulator. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 9, 2020

2008 journal article

In vitro production of metabolism-enhancing phytoecdysteroids from Ajuga turkestanica

Plant Cell, Tissue and Organ Culture, 93(1), 73–83.

By: D. Cheng*, G. Yousef*, M. Grace*, R. Rogers*, J. Gorelick-Feldman*, I. Raskin*, M. Lila*

author keywords: 20-Hydroxyecdysone; cell suspension culture; cyasterone; hairy root; methyl jasmonate; mevalonic acid; turkesterone
TL;DR: The results suggest that sustainable production of metabolically active phytoecdysteroid can be achieved through hairy root culture systems. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 9, 2020

2008 journal article

Plant extracts from central Asia showing antiinflammatory activities in gene expression assays

Phytotherapy Research, 22(7), 929–934.

By: M. Dey*, C. Ripoll*, R. Pouleva*, R. Dorn*, I. Aranovich*, D. Zaurov*, A. Kurmukov, M. Eliseyeva ...

author keywords: antiinflammatory natural product; gene expression; real-time RT-PCR
MeSH headings : Animals; Anti-Inflammatory Agents / pharmacology; Asia, Central; Cell Survival / drug effects; Cyclooxygenase 2 / genetics; Cyclooxygenase 2 / metabolism; Dose-Response Relationship, Drug; Gene Expression / drug effects; Gene Expression Profiling; Inhibitory Concentration 50; Interleukin-1beta / genetics; Interleukin-1beta / metabolism; Macrophages / drug effects; Macrophages / metabolism; Medicine, East Asian Traditional; Mice; Nitric Oxide Synthase Type II / genetics; Nitric Oxide Synthase Type II / metabolism; Phytotherapy; Plant Extracts / pharmacology; Plants, Medicinal / chemistry; RNA, Messenger / metabolism; Reverse Transcriptase Polymerase Chain Reaction
TL;DR: A mouse macrophage‐based quantitative, reverse transcription polymerase chain reaction (qRT‐PCR) system was optimized to screen plant extracts for antiinflammatory activities using three well known genetic markers of inflammation, and extracts identified were able to reduce inflammatory symptoms in vivo. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 9, 2020

2008 journal article

Interaction of Environmental Moisture with Powdered Green Tea Formulations: Effect on Catechin Chemical Stability

Journal of Agricultural and Food Chemistry, 56(11), 4068–4077.

author keywords: green tea; catechin stability; degradation; powder; humidity
MeSH headings : Adsorption; Ascorbic Acid / chemistry; Catechin / chemistry; Drug Stability; Environment; Food Preservation; Humidity; Sodium Nitrite / pharmacology; Tea / chemistry
TL;DR: Results are the first to demonstrate that addition of other dry components to tea powders may affect catechin stability in finished dry blends and highlight the importance of considering the complex interplay between a multicomponent system and its environment for developing stable products. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2008 journal article

Carotenoid Bioaccessibility from Whole Grain and Degermed Maize Meal Products

Journal of Agricultural and Food Chemistry, 56(21), 9918–9926.

By: E. Kean*, B. Hamaker* & M. Ferruzzi*

author keywords: Carotenoids; maize; lutein; carotene; bread; porridge; bioaccessibility
MeSH headings : Biological Availability; Carotenoids / analysis; Food-Processing Industry; Lutein / analysis; Xanthophylls / analysis; Zea mays / chemistry; Zeaxanthins
TL;DR: The results suggest that maize-based food products are good dietary sources of bioaccessible carotenoids and that specific food preparation methods may influence the relative bioaccessibility of individual carotanoid species. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2008 journal article

Impact of the Hard-to-Cook Phenomenon on Phenolic Antioxidants in Dry Beans (Phaseolus vulgaris)

Journal of Agricultural and Food Chemistry, 56(9), 3102–3110.

By: C. Machado*, M. Ferruzzi* & S. Nielsen*

author keywords: common beans; Phaseolus vulgaris; phenolic acids; antioxidant activity; hard-to-cook phenomenon
MeSH headings : Antioxidants / analysis; Food Preservation; Food Technology; Hot Temperature; Hydroxybenzoates / analysis; Phaseolus / chemistry; Phenols / analysis; Seeds / chemistry; Time Factors
TL;DR: This study showed that the HTC phenomenon affected a potential nutritive characteristic of dry beans, and the contents of free and acid hydrolyzable phenolic acids were reduced and the antioxidant activity was reduced. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: August 28, 2020

2008 journal article

Epigallocatechin-3-gallate (EGCG) inhibits PC-3 prostate cancer cell proliferation via MEK-independent ERK1/2 activation

Chemico-Biological Interactions, 171(1), 89–95.

By: D. Albrecht*, E. Clubbs*, M. Ferruzzi* & J. Bomser*

author keywords: epigallocatechin-3-gallate; extracellular signal-regulated kinase; prostate cancer; green tea
MeSH headings : Anticarcinogenic Agents / pharmacology; Catechin / analogs & derivatives; Catechin / pharmacology; Cell Line; Cell Line, Tumor; Cell Proliferation / drug effects; Chromones / pharmacology; Enzyme Activation / drug effects; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Flavonoids / pharmacology; Humans; Inhibitory Concentration 50; Male; Mitogen-Activated Protein Kinase 1 / metabolism; Mitogen-Activated Protein Kinase 3 / metabolism; Mitogen-Activated Protein Kinase Kinases / antagonists & inhibitors; Mitogen-Activated Protein Kinase Kinases / metabolism; Morpholines / pharmacology; Phosphatidylinositol 3-Kinases / metabolism; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation / drug effects; Prostatic Neoplasms / metabolism; Prostatic Neoplasms / pathology; Protein Kinase Inhibitors / pharmacology
TL;DR: Results suggest that ERK1/2 activation via a MEK-independent, PI3-K-dependent signaling pathway is partially responsible for the antiproliferative effects of EGCG in PC-3 cells. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: August 28, 2020

2008 journal article

The Impact of Television Commercials on Food Preferences of Preschoolers

Journal of the American Dietetic Association, 108(9), A112.

By: T. Nicklas*, E. Tsuei-Goh*, L. Goodell*, D. Acuff*, R. Reiher*, R. Buday*, A. Ottenbacher*

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 28, 2020

2008 journal article

The major intestinal metabolites of anthocyanins are unlikely to be conjugates of their parent compounds but metabolites of their degradation products

Proceedings of the Nutrition Society, 67(OCE8).

By: C. Kay*, P. Kroon* & A. Cassidy*

TL;DR: ) does not appear achievable inhuman subjects and the in vitro mechanistic bioactivity of anthocyanins has been exclusively explored using aglycones andglycoside conjugates, despite a lack of evidence establishing these compounds as the biologically-available forms. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020

2008 journal article

Effects of pistachios on cardiovascular disease risk factors and potential mechanisms of action: a dose-response study--

The American Journal of Clinical Nutrition, 88(3), 651–659.

By: S. Gebauer, S. West, C. Kay, P. Alaupovic, D. Bagshaw & P. Kris-Etherton

Source: ORCID
Added: November 13, 2019

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