Works Published in 2017

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Displaying works 101 - 120 of 203 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2017 journal article

Composition and structure of porcine digital flexor tendon-bone insertion tissues

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 105(11), 3050–3058.

author keywords: tendon-bone insertion; collagen fiber orientation; fast fourier transform; time-of-flight secondary ion mass spectrometry
MeSH headings : Animals; Anisotropy; Biomechanical Phenomena; Bone and Bones / chemistry; Collagen / analysis; Minerals / analysis; Spectrometry, Mass, Secondary Ion; Swine; Tendons / chemistry; Tensile Strength
TL;DR: The porcine digital flexor tendon insertion tissue is examined to provide a quantitative description of its collagen orientation and mineral concentration by using Fast Fourier Transform based image analysis and mass spectrometry, respectively. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2017 journal article

A pH-sensitive methenamine mandelate-loaded nanoparticle induces DNA damage and apoptosis of cancer cells

Acta Biomaterialia, 62, 246–256.

By: L. Zhang, W. Hao, L. Xu, Y. Gao, X. Wang, D. Zhu, Z. Chen, X. Zhang, H. Chen, L. Mei

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Usability Comparison of Conventional Direct Control Versus Pattern Recognition Control of Transradial Prostheses

IEEE TRANSACTIONS ON HUMAN-MACHINE SYSTEMS, 47(6), 1146–1157.

author keywords: Biomedical signal; Human factors; Man-machine systems; prosthetics
TL;DR: Empirical efficacy of using eye-tracking-based measures of cognitive load and standardize test paradigms for assessment of upper limb prosthetic usability is illustrated and supports PR prosthetic device control as an intuitive alternative to DC. (via Semantic Scholar)
UN Sustainable Development Goal Categories
8. Decent Work and Economic Growth (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2017 journal article

Three-dimensional assessment of curvature, torsion, and canal flare index of the humerus of skeletally mature nonchondrodystrophic dogs

American Journal of Veterinary Research, 78(10), 1140–1149.

MeSH headings : Animals; Dogs / anatomy & histology; Female; Humans; Humerus / anatomy & histology; Humerus / diagnostic imaging; Male; Models, Anatomic; Tomography, X-Ray Computed / veterinary
TL;DR: CT-based 3-D reconstructions allowed the assessment of shaft angulation, torsion, and CFI, and increased body weight was associated with a lower craniocaudal CFI. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Room Temperature Growth of Epitaxial Titanium Nitride Films by Pulsed Laser Deposition

CRYSTAL GROWTH & DESIGN, 17(12), 6634–6640.

By: D. Rasic n, R. Sachan n, M. Chisholm*, J. Prater & J. Narayan n

Source: Web Of Science
Added: August 6, 2018

2017 journal article

Required hydrophobicity of fluorescent reporters for phosphatidylinositol family of lipid enzymes

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 409(29), 6781–6789.

By: J. Waybright*, W. Huang*, A. Proctor*, X. Wang*, N. Allbritton* & Q. Zhang*

author keywords: Fluorescent reporter; Chemical cytometry; Lipid enzyme; Phosphatidylinositol
MeSH headings : Enzymes / metabolism; Fluorescent Dyes / chemistry; Hydrophobic and Hydrophilic Interactions; Lipids / chemistry; Liposomes / metabolism; Phosphatidylinositols / metabolism
TL;DR: For both enzymes, the fluorescent probe with a longer side chain functions as a better substrate than that with a shorter chain and works well in the presence of the endogenous lipid, highlighting the importance of hydrophobicity of side chains in fluorescent phosphoinositide reporters. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Neutron-activatable needles for radionuclide therapy of solid tumors

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 105(12), 3273–3280.

By: J. Kim*, R. Narayan n, X. Lu* & M. Jay*

author keywords: neutron-activation; brachytherapy; rhenium-molybdenum alloy; pulsed laser deposition; chemical vapor deposition
MeSH headings : Brachytherapy / instrumentation; Coated Materials, Biocompatible / chemistry; Drug Delivery Systems / instrumentation; Equipment Design; Holmium / chemistry; Humans; Molybdenum / chemistry; Needles; Neoplasms / radiotherapy; Neutrons; Rhenium / chemistry; Titanium / chemistry; Transdermal Patch
TL;DR: These coated neutron-activatable needles offer a new approach to internal radiation therapy of tumors that allows precise tailoring of the absorbed radiation dose delivered to the tumor by controlling the coating thickness and the irradiation time. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

KO of 5-InsP(7) kinase activity transforms the HCT116 colon cancer cell line into a hypermetabolic, growth-inhibited phenotype

Proceedings of the National Academy of Sciences of the United States of America, 114(45), 11968–11973.

By: C. Gu, H. Nguyen, D. Ganini, Z. Chen, H. Jessen, Z. Gu, H. Wang, S. Shears

Source: NC State University Libraries
Added: August 6, 2018

2017 article

KIDNEY PHYSIOLOGYA size bandpass filter

Lu, Y., & Gu, Z. (2017, November). NATURE NANOTECHNOLOGY, Vol. 12, pp. 1023–1025.

By: Y. Lu n & Z. Gu n

MeSH headings : Animals; Glomerular Filtration Rate; Humans; Kidney Glomerulus / metabolism; Nanoparticles; Particle Size
TL;DR: The next-generation precision medications and diagnostic tools developed in this study will help improve the quality of life for patients and improve the efficiency of existing treatments. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Interactions Between Transfemoral Amputees and a Powered Knee Prosthesis During Load Carriage

Scientific Reports, 7(1).

By: A. Brandt*, Y. Wen*, M. Liu*, J. Stallings n & H. Huang*

Contributors: A. Brandt*, Y. Wen*, M. Liu*, J. Stallings n & H. Huang*

MeSH headings : Adult; Amputees; Artificial Limbs; Biomechanical Phenomena; Female; Humans; Knee Prosthesis; Male; Middle Aged; Perception; Prosthesis Design; Walking / physiology; Wearable Electronic Devices; Weight-Bearing / physiology; Young Adult
TL;DR: The results suggest transfemoral amputees could benefit from load-adaptive powered knee controllers, and controller adjustments affect amputee users more when they walk with (versus without) load. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID, NC State University Libraries
Added: August 6, 2018

2017 journal article

First-in-Human Study of Acoustic Angiography in the Breast and Peripheral Vasculature

Ultrasound in Medicine & Biology, 43(12), 2939–2946.

author keywords: Contrast-enhanced ultrasound; Breast imaging; Angiography; Superharmonic; Microbubble; Micro-vasculature; Dual frequency
MeSH headings : Acoustics; Angiography; Breast / anatomy & histology; Breast / blood supply; Contrast Media; Feasibility Studies; Female; Fluorocarbons; Hand / anatomy & histology; Hand / blood supply; Humans; Image Enhancement / methods; Male; Microbubbles; Reference Values; Sensitivity and Specificity; Ultrasonography / methods; Wrist / anatomy & histology; Wrist / blood supply
TL;DR: The translation of a contrast-enhanced ultrasound technique, acoustic angiography, to human imaging is described and results indicate that sensitivity and spatial resolution are sufficient to image vessels as small as 0.2 mm in diameter at depths of ~15‬mm in the human breast. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Does dynamic stability govern propulsive force generation in human walking?

ROYAL SOCIETY OPEN SCIENCE, 4(11).

By: M. Browne n & J. Franz n

author keywords: variability; push-off; balance; walking speed; biofeedback; ageing
TL;DR: It is found that young adults adopt an FP at their preferred walking speed that maximizes dynamic stability, and the onset of a diminished push-off in old age may independently contribute to poorer balance control and precipitate slower walking speeds. (via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Chemical fixation to arrest phospholipid signaling for chemical cytometry

JOURNAL OF CHROMATOGRAPHY A, 1523, 97–106.

By: A. Proctor*, C. Sims* & N. Allbritton n

author keywords: Capillary electrophoresis; Phospholipid; Phospholipase C; Diacylglycerol; Chemical cytometry; Chemical fixation
MeSH headings : Electrophoresis, Capillary; Signal Transduction; Tissue Fixation / methods; Type C Phospholipases / metabolism
TL;DR: This methodology enables cell assay with the reporter to be separated in space and time from reporter metabolite quantification while preserving assay integrity, and demonstrates the capability of chemical fixation coupled to single-cell CZE to yield an accurate snapshot of cellular reactions with the probe. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Characterizing Cell Migration Within Three-dimensional In Vitro Wound Environments

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, (126).

By: S. Nandi n & A. Brown n

author keywords: Bioengineering; Issue 126; cell migration; three dimensional; fibrin; wound healing; extracellular matrix; integrins; in vitro wound healing assay
MeSH headings : Bioengineering / methods; Cell Movement / physiology; Humans; Wound Healing / physiology
TL;DR: The method described herein allows for the study of cell migration in a three-dimensional model that better reflects physiological conditions than previously established two-dimensional scratch assays, thus increasing the relevance of in vitro cell studies prior to the use of in vivo animal models. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Two-photon polymerization for biological applications

MATERIALS TODAY, 20(6), 314–322.

By: A. Nguyen n & R. Narayan n

TL;DR: Current research into TPA-sensitive photopolymers with good biocompatibility and holographic projections using spatial light modulators address current technological limitations by providing materials specifically formulated for biological applications and by making better use of available laser power for applications in which nanoscale resolution is not required. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Transgenerational inheritance of neurobehavioral and physiological deficits from developmental exposure to benzo[a]pyrene in zebrafish

TOXICOLOGY AND APPLIED PHARMACOLOGY, 329, 148–157.

By: A. Knecht*, L. Truong*, S. Marvel n, D. Reif n, A. Garcia*, C. Lu*, M. Simbnich, J. Teeguarden*, R. Tanguay*

author keywords: Zebrafish Benzo[a]pyrene; Transgenerational; Neurobehavioral; Developmental toxicity; Physiological deficits; Aryl hydrocarbon receptor
MeSH headings : Animals; Animals, Genetically Modified; Behavior, Animal / drug effects; Benzo(a)pyrene / toxicity; DNA Methylation / drug effects; DNA Modification Methylases / metabolism; Dose-Response Relationship, Drug; Epigenesis, Genetic / drug effects; Genotype; Heart Rate / drug effects; Heredity; Inheritance Patterns / drug effects; Learning / drug effects; Mitochondria / drug effects; Mitochondria / metabolism; Motor Activity / drug effects; Neurotoxicity Syndromes / genetics; Neurotoxicity Syndromes / metabolism; Neurotoxicity Syndromes / physiopathology; Phenotype; Repressor Proteins / agonists; Repressor Proteins / deficiency; Repressor Proteins / genetics; Respiration / drug effects; Risk Assessment; Social Behavior; Time Factors; Water Pollutants, Chemical / toxicity; Zebrafish / genetics; Zebrafish / growth & development; Zebrafish / metabolism; Zebrafish Proteins / agonists; Zebrafish Proteins / deficiency; Zebrafish Proteins / genetics
TL;DR: Exposure to benzo[a]pyrene during development resulted in transgenerational inheritance of neurobehavioral and physiological deficiencies, and indirect evidence suggested the potential for an AHR2‐dependent epigenetic route. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

The effects of Achilles tendon compliance on triceps surae mechanics and energetics in walking

JOURNAL OF BIOMECHANICS, 60, 227–231.

author keywords: Plantarflexor; Musculoskeletal modeling; Forward dynamics; Mechanical power; Metabolic energy
MeSH headings : Achilles Tendon / physiology; Adult; Biomechanical Phenomena; Humans; Male; Muscle, Skeletal / physiology; Walking / physiology
TL;DR: GAS muscle-tendon mechanics and energetics were significantly more sensitive to changes in tendon compliance than were those for SOL, and GAS was not able to return stored tendon energy during push-off as effectively as SOL, particularly for larger values of tendon compliance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Tailoring Biomaterials for Cancer Immunotherapy: Emerging Trends and Future Outlook

ADVANCED MATERIALS, 29(29).

author keywords: biomaterials; cancer immunotherapy; cell therapy; drug delivery
MeSH headings : Animals; Antigen-Presenting Cells / cytology; Antigen-Presenting Cells / metabolism; Antigens / genetics; Antigens / immunology; Antigens / metabolism; Biocompatible Materials / chemistry; Cell- and Tissue-Based Therapy; Humans; Immunologic Factors / metabolism; Immunologic Factors / therapeutic use; Immunotherapy; Nanostructures / chemistry; Neoplasms / therapy
TL;DR: An overview of the latest studies on engineering biomaterials for the enhancement of anticancer immunity is given, including the perspectives of delivery of immunomodulatory therapeutics, engineering immune cells, and constructing immune‐modulating scaffolds. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Piezoelectric Floating Element Shear Stress Sensor for the Wind Tunnel Flow Measurement

IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS, 64(9), 7304–7312.

By: T. Kim n, A. Saini n, J. Kim n, A. Gopalarathnam n, Y. Zhu n, F. Palmieri*, C. Wohl*, X. Jiang n

author keywords: Bimorph piezoelectric (PE) structures; electromechanical symmetry; floating element (FE); PMN-33% PT crystal; shear stress
TL;DR: An analytical model was proposed based on cantilever beam theory with an end-tip-mass for verifying the resonance frequency shift in static stress measurements and the signal-to-noise ratio (SNR) and ambient vibration-filtered pure shear stress sensitivity were obtained through signal processing. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

OPTIMIZING SENSITIVITY OF ULTRASOUND CONTRAST-ENHANCED SUPER-RESOLUTION IMAGING BY TAILORING SIZE DISTRIBUTION OF MICROBUBBLE CONTRAST AGENT

ULTRASOUND IN MEDICINE AND BIOLOGY, 43(10), 2488–2493.

author keywords: Super resolution; Microbubble contrast agent; Sensitivity; Size distribution
MeSH headings : Animals; Contrast Media; Disease Models, Animal; Female; Fibrosarcoma / blood supply; Fibrosarcoma / diagnostic imaging; Image Enhancement / methods; Microbubbles; Microvessels / diagnostic imaging; Particle Size; Phantoms, Imaging; Rats; Rats, Inbred F344; Ultrasonography / methods
TL;DR: Experiments in phantom vessels and in vivo experiments imaging rat tumors revealed that the sensitivity of contrast-enhanced super-resolution imaging can be improved by using microbubbles with a larger diameter. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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