Works Published in 2019

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Displaying works 181 - 200 of 215 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2019 review

Current Advancements in Transdermal Biosensing and Targeted Drug Delivery

[Review of ]. SENSORS, 19(5).

author keywords: Iontophoresis; transdermal biosensing; drug delivery; electroporation; microfabrication; microfluidics; microneedle; luminescent sensors; fluorescent biosensors
MeSH headings : Administration, Cutaneous; Animals; Biosensing Techniques / methods; Drug Delivery Systems / methods; Electroporation / methods; Humans; Iontophoresis / methods; Needles; Pharmaceutical Preparations / administration & dosage
TL;DR: In this manuscript, recent advancements in the area of minimally-invasive transdermal biosensing and drug delivery are reviewed and microneedles have emerged as a novel approach to replace hypodermic needles. (via Semantic Scholar)
Source: Web Of Science
Added: April 15, 2019

2019 journal article

Antibody-Armed Platelets for the Regenerative Targeting of Endogenous Stem Cells

NANO LETTERS, 19(3), 1883–1891.

By: D. Shen n, Z. Li n, S. Hu n, K. Huang n, T. Su n, H. Liang n, F. Liu n, K. Cheng n

author keywords: Myocardium infarction; platelets; endogenous stem cells; antibodies
MeSH headings : Animals; Antigens, CD34 / immunology; Blood Platelets / chemistry; Blood Platelets / immunology; Cell- and Tissue-Based Therapy; Disease Models, Animal; Heart Injuries / genetics; Heart Injuries / pathology; Heart Injuries / therapy; Humans; Mice; Myocardial Infarction / pathology; Myocardial Infarction / therapy; Myocardium / immunology; Myocardium / pathology; Stem Cells / immunology; Stem Cells / metabolism
TL;DR: Taking advantage of the natural infarct-homing ability of platelets, CD34 antibody-linked platelets (P-CD34) are engineered to capture circulating CD34-positive endogenous stem cells and direct them to the injured heart for effective heart repair. (via Semantic Scholar)
Source: Web Of Science
Added: April 2, 2019

2019 journal article

Gait Mechanics and T1 rho MRI of Tibiofemoral Cartilage 6 Months after ACL Reconstruction

MEDICINE & SCIENCE IN SPORTS & EXERCISE, 51(4), 630–639.

By: S. Pfeiffer*, J. Spang*, D. Nissman*, D. Lalush n, K. Wallace*, M. Harkey*, L. Pietrosimone*, R. Schmitz* ...

author keywords: BIOMECHANICS; PROTEOGLYCAN DENSITY; POSTTRAUMATIC; OSTEOARTHRITIS
MeSH headings : Anterior Cruciate Ligament Injuries / diagnostic imaging; Anterior Cruciate Ligament Injuries / physiopathology; Anterior Cruciate Ligament Injuries / surgery; Anterior Cruciate Ligament Reconstruction / methods; Arthroscopy; Biomechanical Phenomena; Cartilage, Articular / chemistry; Cartilage, Articular / diagnostic imaging; Cartilage, Articular / physiopathology; Cross-Sectional Studies; Female; Gait / physiology; Humans; Knee Joint / chemistry; Knee Joint / diagnostic imaging; Knee Joint / physiopathology; Magnetic Resonance Imaging / methods; Male; Osteoarthritis, Knee / etiology; Proteoglycans / analysis; Risk Factors; Young Adult
TL;DR: Associations between outcomes related to lesser mechanical loading during walking and greater T1&rgr; MRI ILR were found 6 months after ACLR, suggesting that underloading of the ACLR limb at 6 monthsAfter ACLR may be associated with lesser proteoglycan density in the ACLr limb compared with the uninjured limb. (via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: April 2, 2019

2019 journal article

Advanced Age Redistributes Positive but Not Negative Leg Joint Work during Walking

MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 51(4), 615–623.

author keywords: ECCENTRIC; CONCENTRIC; BIOMECHANICS; GAIT; AGING
MeSH headings : Adolescent; Adult; Age Factors; Aged; Aging / physiology; Ankle / physiology; Biomechanical Phenomena; Female; Gait Analysis; Humans; Knee / physiology; Leg / physiology; Male; Muscle Contraction / physiology; Muscle, Skeletal / physiology; Walking / physiology; Walking Speed / physiology; Young Adult
TL;DR: Exercise prescription should focus on improving ankle muscle function while preserving knee muscle function in older adults trying to maintain their independence, as distal-to-proximal redistribution of positive joint work during level and uphill walking is absent. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: April 2, 2019

2019 article

Special Issue on Pilot Clinical Translation of New Medical Ultrasound Methodologies

Gallippi, C. M., & Dahl, J. J. (2019, March). IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, Vol. 66, pp. 423–424.

TL;DR: A vital first step to translating these cutting-edge ultrasound methods to clinical implementation is performing pilot studies in humans, in vivo, to demonstrate the feasibility of new methodologies in the context of complex tissue environments with unknown parameters. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: April 2, 2019

2019 journal article

Delineation of Human Carotid Plaque Features In Vivo by Exploiting Displacement Variance

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 66(3), 481–492.

author keywords: Acoustic radiation force impulse (ARFI) imaging; atherosclerosis; carotid endarterectomy (CEA); carotid plaque characterization
MeSH headings : Aged; Carotid Arteries / diagnostic imaging; Carotid Arteries / pathology; Carotid Arteries / surgery; Carotid Stenosis / diagnostic imaging; Carotid Stenosis / pathology; Carotid Stenosis / surgery; Elasticity Imaging Techniques / methods; Endarterectomy, Carotid; Female; Humans; Image Interpretation, Computer-Assisted / methods; Male; Middle Aged; Plaque, Atherosclerotic / diagnostic imaging; Plaque, Atherosclerotic / pathology; Plaque, Atherosclerotic / surgery; Signal-To-Noise Ratio
TL;DR: It is suggested that log(VoA) enhances the differentiation of LRNC, IPH, COL, and CAL in human carotid plaques, in vivo, which is clinically relevant to improving stroke risk prediction and medical management. (via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Source: Web Of Science
Added: April 2, 2019

2019 journal article

Mechanical Anisotropy Assessment in Kidney Cortex Using ARFI Peak Displacement: Preclinical Validation and Pilot In Vivo Clinical Results in Kidney Allografts

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 66(3), 551–562.

By: M. Hossain n, R. Detwiler*, E. Chang*, M. Caughey*, M. Fisher*, T. Nichols*, E. Merricks*, R. Raymer* ...

author keywords: Acoustic radiation force impulse (ARFI); anisotropy; chronic kidney disease (CKD); kidney transplant; renal rejection; shear wave elasticity imaging (SWEI); ultrasound
MeSH headings : Adult; Aged; Allografts / diagnostic imaging; Allografts / physiology; Animals; Anisotropy; Elastic Modulus / physiology; Elasticity Imaging Techniques / methods; Female; Humans; Kidney Cortex / diagnostic imaging; Kidney Cortex / physiology; Kidney Transplantation; Male; Middle Aged; Renal Insufficiency, Chronic / diagnostic imaging; Renal Insufficiency, Chronic / surgery; Swine
TL;DR: The results of this pilot clinical study suggest the feasibility of implementing symmetrical ARF to obviate mechanical anisotropy in the kidney cortex when anisOTropy is a confounding factor and implementing asymmetric ARF in the cortex of human kidney allografts to exploit mechanical an isotropy when mechanicalAnisotropic biomarker is a potentially relevant biomarker. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: April 2, 2019

2019 journal article

Electrocardiogram of a Silver Nanowire Based Dry Electrode: Quantitative Comparison With the Standard Ag/AgCl Gel Electrode

IEEE ACCESS, 7, 20789–20800.

Contributors: Q. Qin n, J. Li*, S. Yao n, C. Liu*, H. Huang n & Y. Zhu n

author keywords: Dry electrode; ambulatory ECG; ECG discrepancy comparison; signal quality indices; heart rate variability analysis
TL;DR: Quantitative comparisons showed that the AgNW electrode could collect acceptable ECG waveforms as the Ag/AgCl electrode in both the sitting and walking conditions, however, the baseline drift and waveform distortions existed in the Ag NW electrode, likely due to electrode motion. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: March 25, 2019

2019 journal article

The relationships of multiple factors to menopausal symptoms in different racial/ethnic groups of midlife women: The structural equation modeling

WOMEN & HEALTH, 59(2), 196–212.

author keywords: Covariates; menopausal symptoms; midlife women; race/ethnicity; structural equation modeling
MeSH headings : Acculturation; Adult; Black or African American / statistics & numerical data; Asian / statistics & numerical data; Ethnicity / statistics & numerical data; Female; Health Status; Hispanic or Latino / statistics & numerical data; Humans; Latent Class Analysis; Menopause / ethnology; Middle Aged; Race Factors; Socioeconomic Factors; Surveys and Questionnaires; United States / ethnology; White People / statistics & numerical data
TL;DR: The model had the highest fit indices for non-Hispanic (NH) White midlife women, and prominent racial/ethnic differences were observed in the relationships of multiple factors to menopausal symptoms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science; OpenAlex)
Source: Web Of Science
Added: March 25, 2019

2019 journal article

Estimating asymmetric information effects in health care with uninsurable costs

INTERNATIONAL JOURNAL OF HEALTH ECONOMICS AND MANAGEMENT, 19(1), 79–98.

author keywords: Moral hazard; Adverse selection; Health insurance; Transaction costs; C14; D82; I11
TL;DR: A structural approach is used to separately estimate moral hazard and adverse selection effects in health care utilization using hospital invoices data and indicates statistically significant and economically meaningful moral hazard in the population of patients with non life-threatening diagnoses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: March 25, 2019

2019 journal article

EFFECT OF HYDROSTATIC PRESSURE, BOUNDARY CONSTRAINTS AND VISCOSITY ON THE VAPORIZATION THRESHOLD OF LOW-BOILING-POINT PHASE-CHANGE CONTRAST AGENTS

ULTRASOUND IN MEDICINE AND BIOLOGY, 45(4), 968–979.

author keywords: Phase change; Contrast agents; Acoustic droplet vaporization; Vaporization threshold; Decafluoro-butane; Nanoemulsion
MeSH headings : Animals; Contrast Media / administration & dosage; Female; Hydrostatic Pressure; Image Enhancement / methods; Kidney / anatomy & histology; Models, Animal; Rats; Rats, Inbred F344; Ultrasonography / methods; Viscosity; Volatilization
TL;DR: Constraints caused by the surrounding tissue and capillary walls, as well as increased viscosity in vivo, contribute to the increased vaporization threshold compared with in vitro experiments, although more work is required to confirm all relevant factors. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: March 18, 2019

2019 journal article

Electrical Transition in Isostructural VO2 Thin-Film Heterostructures

SCIENTIFIC REPORTS, 9.

TL;DR: This work designs a novel strain-stabilized isostructural VO2 epitaxial thin-film system where the electrical transition occurs without any observable structural transition, and calculates that the strain in monoclinic structure reduces the difference between long and short V-V bond-lengths in monOClinic structures which leads to a systematic decrease in the electronic bandgap of VO2. (via Semantic Scholar)
Source: Web Of Science
Added: March 18, 2019

2019 journal article

Dynamic assessment of dual-frequency microbubble-mediated sonothrombolysis in vitro

JOURNAL OF APPLIED PHYSICS, 125(8).

By: D. Suo n, B. Govind n, J. Gu n, P. Dayton n & Y. Jing n

TL;DR: It is found that dual- frequencies excitation in general produces a faster rate of clot dissipation in comparison to single-frequency excitation, and this observation is corroborated by cavitation signal detection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: March 18, 2019

2019 journal article

Ultrasound Measurement of Vascular Density to Evaluate Response to Anti-Angiogenic Therapy in Renal Cell Carcinoma

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 66(3), 873–880.

By: J. Rojas n, V. Papadopoulou n, T. Czernuszewicz*, R. Rajamahendiran*, A. Chytil*, Y. Chiang*, D. Chong*, V. Bautch ...

author keywords: Microvasculature; angiogenesis; ultrasound; contrast agents; response to therapy; acoustic angiography
MeSH headings : Angiogenesis Inhibitors / pharmacology; Angiography / methods; Animals; Carcinoma, Renal Cell / blood supply; Carcinoma, Renal Cell / diagnostic imaging; Drug Monitoring; Female; Heterografts; Kidney / blood supply; Kidney / diagnostic imaging; Kidney Neoplasms / blood supply; Kidney Neoplasms / diagnostic imaging; Mice; Mice, Inbred NOD; Mice, SCID; Microvessels / diagnostic imaging; Microvessels / drug effects; Microvessels / pathology; Ultrasonography / methods
TL;DR: Results suggest that future applications utilizing ultrasound imaging to monitor tumor response to therapy may be able to provide earlier insight into tumor behavior from metrics of microvascular density rather than anatomical tumor size measurements. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: March 11, 2019

2019 journal article

Third generation impedimetric sensor employing direct electron transfer type glucose dehydrogenase

BIOSENSORS & BIOELECTRONICS, 129, 189–197.

By: Y. Ito*, J. Okuda-Shimazaki n, W. Tsugawa*, N. Loew n, I. Shitanda*, C. Lin*, J. La Belle*, K. Sode n

author keywords: Faradaic electrochemical impedance spectroscopy; Impedimetric biosensor; Direct electron transfer; FAD dependent glucose dehydrogenase complex; Charge transfer resistance; Imaginary impedance monitoring
MeSH headings : Bacteria / enzymology; Biosensing Techniques / methods; Electric Impedance; Electrodes; Electron Transport; Flavin-Adenine Dinucleotide / chemistry; Glucose / analysis; Glucose 1-Dehydrogenase / chemistry; Gold / chemistry
TL;DR: The 3rd-generation faradaic enzyme EIS sensor would provide alternative platform for future impedimetric immunosensing system, which does not use redox probe, according to its potential application as the future immunosensor platform. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: March 11, 2019

2019 journal article

Formation and characterization of nano- and microstructures of twinned cubic boron nitride

PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 21(4), 1700–1710.

TL;DR: It is envisage that the controlled growth of phase-pure nano and microstructures of twinned c-BN and their temperature-dependent Raman-active vibrational mode studies will have a tremendous impact on low-temperature solid-state electrical and mechanical devices. (via Semantic Scholar)
Source: Web Of Science
Added: March 11, 2019

2019 journal article

Development of an EMG-Controlled Serious Game for Rehabilitation

IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING, 27(2), 283–292.

By: M. Ghassemi n, K. Triandafilou*, A. Barry*, M. Stoykov*, E. Roth*, F. Mussa-Ivaldi, D. Kamper n, R. Ranganathan*

author keywords: EMG; rehabilitation; serious game
MeSH headings : Adult; Biomechanical Phenomena; Calibration; Electromyography / methods; Female; Functional Laterality; Games, Experimental; Hand / physiopathology; Healthy Volunteers; Humans; Male; Muscle, Skeletal / physiopathology; Psychomotor Performance; Recovery of Function; Stroke Rehabilitation / instrumentation; Young Adult
TL;DR: A novel platform for playing a serious game through electromyographic control is developed and holds promise for rehabilitation of control of muscle activation patterns. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: March 4, 2019

2019 journal article

Cells exhibiting strong p16(INK4a) promoter activation in vivo display features of senescence

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 116(7), 2603–2611.

author keywords: senescence; cdkn2a; aging
MeSH headings : Animals; Cell Proliferation; Cellular Senescence / genetics; Cyclin-Dependent Kinase Inhibitor p16 / genetics; Enzyme Activation; Fibroblasts / metabolism; Half-Life; Humans; Mice; Phenotype; Promoter Regions, Genetic; RNA, Messenger / genetics; beta-Galactosidase / metabolism
TL;DR: A reporter allele is described, p16tdTom, enabling the in vivo identification and isolation of cells featuring high-level activation of the p16INK4a promoter, displaying characteristics of senescence. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: February 25, 2019

2019 article

On the Quantitative Potential of Viscoelastic Response (VisR) Ultrasound Using the One-Dimensional Mass-Spring-Damper Model (vol 63, pg 1276, 2016)

Selzo, M. R., Moore, C. J., Hossain, M. M., Palmeri, M. L., & Gallippi, C. M. (2019, January). IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, Vol. 66, pp. 251–251.

By: M. Selzo n, C. Moore n, M. Hossain n, M. Palmeri* & C. Gallippi n

TL;DR: In the original publication of this paper, equation (3) contained sign errors for the amplitude of the third and fourth Heaviside functions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: February 18, 2019

2019 journal article

Platelet-like particles dynamically stiffen fibrin matrices and improve wound healing outcomes

BIOMATERIALS SCIENCE, 7(2), 669–682.

MeSH headings : Animals; Biomimetic Materials / chemistry; Blood Platelets / metabolism; Blood Platelets / physiology; Fibrin / chemistry; Fibrin / pharmacology; Humans; Mechanical Phenomena; Mice; Platelet Activation / drug effects; Skin / drug effects; Skin / injuries; Wound Healing / drug effects
TL;DR: The utility of PLPs for enhancing wound repair is demonstrated and the role of native platelet-mediated clot retraction in wound healing is provided, to provide insight into the role in vitro and in vivo models of wound healing. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: February 18, 2019

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