Works Published in 2011
Displaying works 21 - 40 of 123 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2011 journal article
A potential mechanism of action of dietary anthocyanins: modulation of endothelial superoxide production by phenolic acid metabolites
Proceedings of the Nutrition Society, 70(OCE4).
TL;DR:
Evidence is presented that anthocyanins and their metabolites attenuate Ang II-induced endothelial superoxide production and that the cellular activity of anthocianins was enhanced following degradation and metabolism to phenolic acid metabolites.
(via Semantic Scholar)
www.cambridge.org (publisher PDF)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020
2011 journal article
Reply to C Drossard et al
The American Journal of Clinical Nutrition, 93(4), 866–867.
Sources: Web Of Science, NC State University Libraries
Added: January 5, 2020
2011 journal article
Subtyping Salmonella enterica Serovar Enteritidis Isolates from Different Sources by Using Sequence Typing Based on Virulence Genes and Clustered Regularly Interspaced Short Palindromic Repeats (CRISPRs)
Applied and Environmental Microbiology, 77(13), 4520–4526.
MeSH headings : Animals; Chickens; Cluster Analysis; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Disease Outbreaks; Eggs; Environmental Microbiology; Food Microbiology; Genotype; Humans; Inverted Repeat Sequences; Molecular Sequence Data; Molecular Typing / methods; Salmonella Infections / microbiology; Salmonella Infections, Animal / microbiology; Salmonella enteritidis / classification; Salmonella enteritidis / genetics; Salmonella enteritidis / isolation & purification; Sequence Analysis, DNA; United States / epidemiology; Virulence Factors / genetics
TL;DR:
A sequence typing scheme based on virulence genes and clustered regularly interspaced short palindromic repeats (CRISPR) identified three persistent and predominate STs circulating among U.S. human clinical isolates and chicken, egg, and hen house environmental isolates in Pennsylvania, and a potential environment-specific sequence type.
(via Semantic Scholar)
Source: ORCID
Added: January 2, 2020
2011 journal article
Novel Virulence Gene and Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) Multilocus Sequence Typing Scheme for Subtyping of the Major Serovars of Salmonella enterica subsp. enterica
Applied and Environmental Microbiology, 77(6), 1946–1956.
MeSH headings : Alleles; Cluster Analysis; DNA, Bacterial / genetics; Electrophoresis, Gel, Pulsed-Field; Molecular Sequence Data; Multilocus Sequence Typing / methods; Polymerase Chain Reaction; Polymorphism, Genetic / genetics; Salmonella enterica / classification; Salmonella enterica / genetics; Virulence / genetics
TL;DR:
The novel MLST scheme described in the present study accurately differentiated outbreak strains/clones of the major serovars of Salmonella, and therefore, it shows promise for subtyping this important food-borne pathogen during investigations of outbreaks.
(via Semantic Scholar)
Source: ORCID
Added: January 2, 2020
2011 journal article
Cas3 is a single-stranded DNA nuclease and ATP-dependent helicase in the CRISPR/Cas immune system
The EMBO Journal, 30(7), 1335–1342.
author keywords: Cas3; CRISPR; Ecoli subtype; site-directed mutagenesis; Streptococcus thermophilus
MeSH headings : Adenosine Triphosphate / metabolism; Cloning, Molecular; DNA Helicases / genetics; DNA Helicases / metabolism; DNA Mutational Analysis; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; DNA, Single-Stranded / metabolism; Escherichia coli / genetics; Gene Expression; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Repetitive Sequences, Nucleic Acid; Sequence Analysis, DNA; Streptococcus thermophilus / enzymology; Streptococcus thermophilus / genetics
TL;DR:
It is proposed that the Cas3 ATPase/helicase domain acts as a motor protein, which assists delivery of the nuclease activity to Cascade–crRNA complex targeting foreign DNA.
(via Semantic Scholar)
Source: ORCID
Added: January 2, 2020
2011 journal article
Short communication: The complete genome sequence of Bifidobacterium animalis subspecies animalis ATCC 25527T and comparative analysis of growth in milk with B. animalis subspecies lactis DSM 10140T
Journal of Dairy Science, 94(12), 5864–5870.
author keywords: Bifidobacterium animalis ssp animalis; genome; growth in milk; clustered regularly interspaced short palindromic repeats (CRISPR)
MeSH headings : Animals; Base Sequence; Bifidobacterium / genetics; Bifidobacterium / growth & development; DNA, Intergenic / genetics; Genome, Bacterial / genetics; Inverted Repeat Sequences / genetics; Milk / microbiology; Molecular Sequence Data; Sequence Alignment; Sequence Analysis, DNA / methods; Sequence Homology, Nucleic Acid
Source: ORCID
Added: January 2, 2020
2011 journal article
Evolution and classification of the CRISPR–Cas systems
Nature Reviews Microbiology, 9(6), 467–477.
MeSH headings : Adaptive Immunity / genetics; Archaea / genetics; Archaeal Proteins / classification; Archaeal Proteins / genetics; Bacterial Proteins / classification; Bacterial Proteins / genetics; Genome, Bacterial; Phylogeny; Repetitive Sequences, Nucleic Acid
TL;DR:
An updated analysis of the evolutionary relationships between CRISPR–Cas systems and Cas proteins is provided and a 'polythetic' classification that integrates the phylogenies of the most common cas genes, the sequence and organization of theCRISPR repeats and the architecture of the CRISpr–cas loci is proposed.
(via Semantic Scholar)
Source: ORCID
Added: January 2, 2020
2011 journal article
CRISPR-Cas Systems in Bacteria and Archaea: Versatile Small RNAs for Adaptive Defense and Regulation
Annual Review of Genetics, 45(1), 273–297.
author keywords: coevolution; immunity; interference; RNAi; bacteriophage
MeSH headings : Adaptive Immunity; Archaea / chemistry; Archaea / genetics; Archaea / immunology; Archaea / virology; Bacteria / chemistry; Bacteria / genetics; Bacteria / immunology; Bacteria / virology; Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Bacterial Proteins / immunology; Bacteriophages / genetics; Bacteriophages / immunology; CRISPR-Associated Proteins; Computational Biology; Endodeoxyribonucleases / chemistry; Endodeoxyribonucleases / genetics; Escherichia coli Proteins; Evolution, Molecular; Gene Expression Regulation, Archaeal; Gene Expression Regulation, Bacterial; Genetic Loci; Plasmids / immunology; RNA Interference; RNA Processing, Post-Transcriptional; RNA, Archaeal / chemistry; RNA, Archaeal / genetics; RNA, Archaeal / immunology; RNA, Bacterial / chemistry; RNA, Bacterial / genetics; RNA, Bacterial / immunology; RNA, Small Untranslated / chemistry; RNA, Small Untranslated / genetics; RNA, Small Untranslated / immunology; Transcription, Genetic; Virus Diseases / genetics; Virus Diseases / immunology; Virus Diseases / virology
TL;DR:
Exciting breakthroughs in understanding the mechanisms of the CRISPR-Cas system and its potential for biotechnological applications and understanding evolutionary dynamics are discussed.
(via Semantic Scholar)
Source: ORCID
Added: January 2, 2020
2011 journal article
The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli
Nucleic Acids Research, 39(21), 9275–9282.
MeSH headings : Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Bacteriophage lambda / genetics; Base Sequence; Cloning, Molecular; DNA, Bacterial / chemistry; Escherichia coli / genetics; Escherichia coli / immunology; Escherichia coli / virology; Immunity; Molecular Sequence Data; Mutation; Nucleotide Motifs; Plasmids / genetics; Protein Structure, Tertiary; Repetitive Sequences, Nucleic Acid; Streptococcus thermophilus / genetics; Transformation, Bacterial
TL;DR:
The results show that active CRISPR/Cas systems can be transferred across distant genera and provide heterologous interference against invasive nucleic acids and can be leveraged to develop strains more robust against phage attack, and safer organisms less likely to uptake and disseminate plasmid-encoded undesirable genetic elements.
(via Semantic Scholar)
Source: ORCID
Added: January 2, 2020
2011 article
Lactic Acid Bacteria Defenses Against Phages
Stress Responses of Lactic Acid Bacteria, pp. 459–478.
TL;DR:
This chapter highlights the most broadly used phage-resistance systems in LAB, with an emphasis on the novel CRISPR/Cas system, which provides acquired adaptive immunity against phages by targeting viral nucleic acid in a sequence-specific manner.
(via Semantic Scholar)
Source: ORCID
Added: January 2, 2020
2011 article
Genus Lactobacillus
Lactic Acid Bacteria, pp. 77–91.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: ORCID
Added: January 2, 2020
2011 journal article
Effects of sugar-sweetened and sugar-free cocoa on endothelial function in overweight adults
International Journal of Cardiology, 149(1), 83–88.
author keywords: Cocoa; Endothelial function; Cardiac risk
MeSH headings : Adult; Biomarkers / metabolism; Brachial Artery / drug effects; Brachial Artery / physiology; Cacao; Cardiovascular Diseases / diet therapy; Cardiovascular Diseases / epidemiology; Cardiovascular Diseases / prevention & control; Cholesterol / blood; Cross-Over Studies; Dietary Sucrose / administration & dosage; Endothelium, Vascular / drug effects; Endothelium, Vascular / physiology; Female; Humans; Male; Middle Aged; Overweight / diet therapy; Overweight / epidemiology; Placebos; Risk Factors; Vasodilation / drug effects; Vasodilation / physiology
TL;DR:
Daily cocoa ingestion improves EF independently of other biomarkers of cardiac risk, and does not cause weight gain, and sugar-free preparations may further augment endothelial function.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: November 13, 2019
2011 journal article
A gram scale synthesis of a multi-13 C-labelled anthocyanin,[6, 8, 10, 3′, 5′-13 C 5] cyanidin-3-glucoside, for use in oral tracer studies in humans
Chemical Communications, 47(38), 10596–10598.
Source: ORCID
Added: November 13, 2019
2011 journal article
Anthocyanin-derived phenolic acids form glucuronides following simulated gastrointestinal digestion and microsomal glucuronidation
Molecular Nutrition & Food Research, 55(3), 378–386.
Source: ORCID
Added: November 13, 2019
2011 journal article
Enzyme hydrolysis and ethanol fermentation of dilute ammonia pretreated energy cane
Bioresource Technology, 102(6), 4444–4448.
author keywords: Ammonia pretreatment; Energy cane; Ethanol; Lignocellulosic
MeSH headings : Ammonia / pharmacology; Biofuels / analysis; Biomass; Biotechnology / methods; Cellulase / metabolism; Cellulose / metabolism; Ethanol / metabolism; Fermentation / drug effects; Hydrolysis / drug effects; Saccharum / drug effects; Saccharum / metabolism
TL;DR:
The enzymatic digestibility was related to the removal of lignin and hemicellulose, perhaps due to increased surface area and porosity resulting in the deformation and swelling of exposed fibers as shown in the SEM pictures.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Source: ORCID
Added: June 24, 2019
2011 journal article
COMSOL Multiphysics model for continuous flow microwave heating of liquids
Journal of Food Engineering, 104(3), 422–429.
Contributors: D. Salvi* , D. Boldor *, G. Aita * & C. Sabliov *
author keywords: COMSOL; Continuous microwave heating; Numerical model
Source: ORCID
Added: June 24, 2019
2011 article
Specialized adaptation of a lactic acid bacterium to the milk environment: the comparative genomics of Streptococcus thermophilus LMD-9
Goh, Y. J., Goin, C., O'Flaherty, S., Altermann, E., & Hutkins, R. (2011, August 30). MICROBIAL CELL FACTORIES, Vol. 10.
MeSH headings : Animals; Cattle; Computational Biology; Dairy Products / microbiology; Genomics; Humans; Lactic Acid / metabolism; Milk / microbiology; Streptococcus thermophilus / genetics; Streptococcus thermophilus / metabolism
TL;DR:
The genome of S. thermophilus LMD-9 is shaped by its domestication in the dairy environment, with gene features that conferred rapid growth in milk, stress response mechanisms and host defense systems that are relevant to its industrial applications.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Promoting Wellness in Alaskan Villages: Integrating Traditional Knowledge and Science of Wild Berries
ECOHEALTH, 8(2), 199–209.
author keywords: traditional ecological knowledge; wild berries; environmental change; participatory research; youth; health; community wellness
MeSH headings : Alaska; Alcoholism / ethnology; Analysis of Variance; Climate Change; Community-Based Participatory Research; Environmental Pollution / adverse effects; Ethnobotany / methods; Feeding Behavior / ethnology; Focus Groups; Fruit / chemistry; Fruit / physiology; Health Knowledge, Attitudes, Practice / ethnology; Health Promotion / methods; Humans; Indians, North American; Interviews as Topic; Inuit; Social Behavior
TL;DR:
Multiple berry species were found to have powerful bioactive health properties for ameliorating metabolic syndrome as well as importance for community wellness and suggest the importance of incorporating locally available foods and socio-cultural traditions into community wellness programming.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
A vane-in-cup approach to measure viscoelastic properties of gelatin gels through torque-time responses from brookfield YR-I viscometer
Applied Rheology, 21(6).
Source: NC State University Libraries
Added: August 6, 2018
2011 personal communication
Probiotic and prebiotic claims in Europe: seeking a clear roadmap
Guarner, F., Sanders, M. E., Gibson, G., Klaenhammer, T., Cabana, M., Scott, K., … Hill, C. (2011, December).
MeSH headings : Europe; Prebiotics; Probiotics
TL;DR:
The scientists and clinical investigators belonging to the Board of Directors of the International Scientific Association for Probiotics and Prebiotics (ISAPP) are concerned that claims supported by solid scientific evidence are also being rejected, and there is a lack of clarity regarding the criteria – from study design through wording of the claim – for a dossier suitable for a positive regulatory opinion.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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