Works Published in 2010

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Displaying works 81 - 100 of 135 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2010 journal article

Factors Associated with the Acquisition and Severity of Gestational Listeriosis

PLOS ONE, 5(9).

By: M. Suyemoto n, P. Spears n, T. Hamrick*, J. Barnes n, E. Havell n & P. Orndorff n

MeSH headings : Animals; Disease Models, Animal; Female; Humans; Listeria / physiology; Listeriosis / embryology; Listeriosis / microbiology; Listeriosis / pathology; Liver / microbiology; Liver / pathology; Mice; Pregnancy; Pregnancy Complications, Infectious / microbiology; Pregnancy Complications, Infectious / pathology; Severity of Illness Index; Spleen / microbiology; Spleen / pathology
TL;DR: It was determined in mice that increased susceptibility to lethal infection following oral inoculation begins surprisingly early in pregnancy and extends through embryonic development, and the window of listeriosis susceptibility afforded by pregnancy may be open longer than previously appreciated. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Evaluation of 30-and 25-diopter intraocular lens implants in equine eyes after surgical extraction of the lens

AMERICAN JOURNAL OF VETERINARY RESEARCH, 71(7), 809–816.

MeSH headings : Animals; Anterior Chamber / surgery; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / therapeutic use; Euthanasia, Animal; Eye Enucleation / methods; Eye Enucleation / veterinary; Horse Diseases / surgery; Horses; Lens Implantation, Intraocular / methods; Lens Implantation, Intraocular / veterinary; Lens, Crystalline / anatomy & histology; Lens, Crystalline / surgery; Lenses, Intraocular / veterinary; Refraction, Ocular / physiology; Refractive Errors / therapy; Refractive Errors / veterinary; Refractive Surgical Procedures / methods; Refractive Surgical Procedures / veterinary
TL;DR: Investigation of intraocular lens (IOL) implant strength to approximate emmetropia in horses found insertion of 30-D (enucleated globes) and 25-D IOL implants (adult horses) resulted in overcorrection of refractive error. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Efficacy and Pharmacokinetics of Pantoprazole in Alpacas

JOURNAL OF VETERINARY INTERNAL MEDICINE, 24(4), 949–955.

author keywords: Camelid; Gastrointestinal agents; Pharmacology; Physiology-gastrointestinal tract
MeSH headings : 2-Pyridinylmethylsulfinylbenzimidazoles / pharmacokinetics; 2-Pyridinylmethylsulfinylbenzimidazoles / therapeutic use; Animals; Anti-Ulcer Agents / pharmacokinetics; Anti-Ulcer Agents / therapeutic use; Camelids, New World; Hydrogen-Ion Concentration; Pantoprazole; Stomach Ulcer / prevention & control; Stomach Ulcer / veterinary
TL;DR: Based on the results of this study, pantoprazole represents a safe and effective drug for increasing 3rd compartment pH in camelids and either IV or SC administration is likely to be an effective treatment for gastric ulcers. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Documentation of In Vivo and In Vitro Aerobic Resistance of Feline Tritrichomonas foetus Isolates to Ronidazole

JOURNAL OF VETERINARY INTERNAL MEDICINE, 24(4), 1003–1007.

By: J. Gookin n, S. Stauffer n, D. Dybas & D. Cannon*

author keywords: 5-nitroimidazole; Feline; Resistance; Treatment; Trichomonas
MeSH headings : Aerobiosis; Animals; Antiprotozoal Agents / pharmacology; Cat Diseases / drug therapy; Cat Diseases / parasitology; Cats; Drug Resistance; Male; Metronidazole / pharmacology; Metronidazole / therapeutic use; Ronidazole / pharmacology; Tinidazole / pharmacology; Tinidazole / therapeutic use; Tritrichomonas foetus / drug effects
TL;DR: Clinical resistance to metronidazole, low efficacy of tinidrazole, and present documentation of in vivo and in vitro resistance to ronidazoles in some cats are consistent with a high level of cross resistance of feline T. foetus to 5-nitroimidazol drugs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2010 journal article

Altered Ferritin Subunit Composition: Change in Iron Metabolism in Lens Epithelial Cells and Downstream Effects on Glutathione Levels and VEGF Secretion

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 51(9), 4437–4446.

By: J. Harned n, J. Ferrell n, M. Lall n, L. Fleisher n, S. Nagar n, M. Goralska n, M. McGahan n

MeSH headings : Animals; Apoferritins / genetics; Apoferritins / metabolism; Cell Nucleus / metabolism; Cells, Cultured; Culture Media, Conditioned / pharmacology; Cystine / pharmacokinetics; Dogs; Epithelial Cells / cytology; Epithelial Cells / metabolism; Glutathione / metabolism; Homeostasis / physiology; Hypoxia-Inducible Factor 1, alpha Subunit / metabolism; Iron / metabolism; Lens, Crystalline / cytology; Lens, Crystalline / metabolism; Oxidative Stress / physiology; Protein Subunits / genetics; Protein Subunits / metabolism; RNA, Small Interfering; Transfection; Vascular Endothelial Growth Factor A / metabolism
TL;DR: Iron storage in ferritin was greatly reduced by FHsiRNA, resulting in increased iron availability, as noted by a decrease in transferrin receptor levels and iron uptake from transferrin, and profound effects clearly demonstrate that maintenance of a specific H:L ratio is part of a basic cellular homeostatic mechanism. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 book

A guided tour of veterinary anatomy

Raleigh: Millenium Print Group.

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

ULTRASONOGRAPHIC FINDINGS IN CAIRN TERRIERS WITH PRECLINICAL RENAL DYSPLASIA

VETERINARY RADIOLOGY & ULTRASOUND, 51(4), 453–457.

author keywords: dysplasia; renal; ultrasound
MeSH headings : Aging; Animals; Biopsy / veterinary; Dog Diseases / diagnostic imaging; Dog Diseases / pathology; Dogs; Female; Functional Laterality; Kidney Diseases, Cystic / diagnostic imaging; Kidney Diseases, Cystic / pathology; Kidney Diseases, Cystic / veterinary; Male; Polycystic Kidney Diseases / diagnostic imaging; Polycystic Kidney Diseases / pathology; Polycystic Kidney Diseases / veterinary; Ultrasonography / methods; Ultrasonography / veterinary
TL;DR: The ability to detect dysplastic changes before clinical signs develop makes ultrasound a potentially useful screening method for canine renal dysplasia. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Triclosan exposure modulates estrogen-dependent responses in the female Wistar rat

Toxicological Sciences, 117(1), 45–53.

By: T. Stoker, E. Gibson & L. Zorrilla

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Transforming growth factor-beta (TGF beta) and its signaling components in peni-ovulatory pig follicles

ANIMAL REPRODUCTION SCIENCE, 120(1-4), 84–94.

author keywords: Pig; TGF beta; Peri-ovulatory follicles; Luteinization; Granulosa cells; Progesterone
MeSH headings : Animals; Aromatase / genetics; Aromatase / metabolism; Cells, Cultured; Female; Gene Expression Profiling; Ligands; Luteinization / blood; Luteinization / genetics; Luteinization / metabolism; Ovarian Follicle / metabolism; Ovarian Follicle / physiology; Ovulation / blood; Ovulation / genetics; Ovulation / metabolism; Phosphoproteins / genetics; Phosphoproteins / metabolism; Progesterone / blood; Progesterone / metabolism; Receptors, Transforming Growth Factor beta / genetics; Receptors, Transforming Growth Factor beta / metabolism; Signal Transduction / genetics; Signal Transduction / physiology; Smad Proteins / genetics; Smad Proteins / metabolism; Swine / genetics; Swine / metabolism; Swine / physiology; Time Factors; Transforming Growth Factor beta / blood; Transforming Growth Factor beta / genetics; Transforming Growth Factor beta / metabolism
TL;DR: Data from the present study on temporal and spatial patterns of expression of the TGFbeta-system suggest that TGF beta may play a role in the overall process of luteinization, but it appears not to influence steroidogenesis in lute inizing pig follicles. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2010 journal article

The effects of simazine, a chlorotriazine herbicide, on pubertal development in the female Wistar rat

Reproductive Toxicology (Elmsford, N.Y.), 29(4), 393–400.

By: L. Zorrilla, E. Gibson & T. Stoker

Source: NC State University Libraries
Added: August 6, 2018

2010 book

The College of Veterinary Medicine, North Carolina State University: A personal perspective of its founding

Raleigh, N.C.: North Carolina Veterinary Medical Foundation.

By: T. Curtin

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Temporal Changes in Expression of FoxA1 and Wnt7A in Isolated Adult Human Alveolar Epithelial Cells Enhanced by Heparin

ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY, 293(6), 938–946.

By: K. Apparao n, D. Newman n, H. Zhang n, J. Khosla n, S. Randell* & P. Sannes n

author keywords: beta-catenin; differentiation; heparin; sulfated extracellular matrices
MeSH headings : Adult; Anticoagulants / physiology; Biomarkers / metabolism; Cell Differentiation / drug effects; Cell Differentiation / physiology; Cell Line; Cell Separation; Cells, Cultured; Heparin / physiology; Hepatocyte Nuclear Factor 3-alpha / biosynthesis; Hepatocyte Nuclear Factor 3-alpha / genetics; Humans; Pulmonary Alveoli / cytology; Pulmonary Alveoli / drug effects; Pulmonary Alveoli / metabolism; Respiratory Mucosa / cytology; Respiratory Mucosa / drug effects; Respiratory Mucosa / metabolism; Time Factors; Wnt Proteins / biosynthesis; Wnt Proteins / genetics; beta Catenin / biosynthesis; beta Catenin / genetics
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS) Protein Regulation of Human Neutrophil Migration

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 42(5), 586–594.

author keywords: inflammation; adhesion; beta 2 integrin; actin
MeSH headings : Actins / metabolism; CD18 Antigens / metabolism; Cell Adhesion / drug effects; Cell Membrane / drug effects; Cell Membrane / metabolism; Cell Polarity / drug effects; Chemotactic Factors / pharmacology; Chemotaxis, Leukocyte / drug effects; Humans; Intracellular Signaling Peptides and Proteins / metabolism; Membrane Proteins / metabolism; Myristoylated Alanine-Rich C Kinase Substrate; N-Formylmethionine Leucyl-Phenylalanine / pharmacology; Neutrophils / cytology; Neutrophils / drug effects; Neutrophils / metabolism; Peptides / pharmacology; Tetradecanoylphorbol Acetate / pharmacology
TL;DR: Treating isolated human neutrophils with MANS significantly inhibited both their migration and beta2 integrin-dependent adhesion in response to N-formyl-methionyl-leucyl-phenylalanine (fMLF), IL-8, or leukotriene (LT)B(4). (via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Modeling the interaction of binary and ternary mixtures of estradiol with bisphenol A and bisphenol AF in an in vitro estrogen-mediated transcriptional activation assay (T47D-Kbluc)

Toxicological Sciences, 116(2), 477–487.

By: D. Bermudez, L. Gray & V. Wilson

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Meniscal Mineralization in Domestic Cats

VETERINARY SURGERY, 39(5), 545–552.

By: M. Freire n, J. Brown n, I. Robertson n, A. Pease n, J. Hash n, S. Hunter n, W. Simpson*, A. Sumrell n, B. Lascelles n

MeSH headings : Age Factors; Animals; Calcinosis / diagnostic imaging; Calcinosis / pathology; Calcinosis / veterinary; Cat Diseases / diagnostic imaging; Cat Diseases / pathology; Cats; Female; Joint Diseases / diagnostic imaging; Joint Diseases / pathology; Joint Diseases / veterinary; Male; Menisci, Tibial / diagnostic imaging; Menisci, Tibial / pathology; Pain Measurement / veterinary; Prospective Studies; Radiography; Stifle / diagnostic imaging; Stifle / pathology
TL;DR: Meniscal mineralization is a common condition in domestic cats and seems to indicate medial compartment DJD, which is a cause, or a consequence of joint degeneration, in dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

MRI FEATURES OF METACARPO(TARSO) PHALANGEAL REGION LAMENESS IN 40 HORSES

VETERINARY RADIOLOGY & ULTRASOUND, 51(4), 404–414.

By: L. Gonzalez n, M. Schramme n, I. Robertson n, D. Thrall n & R. Redding n

author keywords: equine; fetlock; high-field magnetic resonance imaging; metacarpophalangeal joint; metatarsophalangeal joint
TL;DR: MRI provided information that was complementary to radiography, ultrasonography, and nuclear scintigraphy and that allowed for a comprehensive evaluation of all structures in the MP joint region and a diagnosis in all 40 horses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2010 article

MARCKS-related peptide modulates in vivo the secretion of airway Muc5ac (Retracted article. See vol. 309, pg. L 750, 2015)

Foster, W. M., Adler, K. B., Crews, A. L., Potts, E. N., Fischer, B. M., & Voynow, J. A. (2010, September). AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, Vol. 299, pp. L345–L352.

By: W. Foster*, K. Adler n, A. Crews n, E. Potts*, B. Fischer* & J. Voynow*

author keywords: myristoylated alanine-rich C kinase substrate; airway hyperresponsiveness; elastase; serotonin
MeSH headings : Aerosols; Animals; Bronchoalveolar Lavage Fluid / chemistry; Cytokines / metabolism; Goblet Cells / pathology; Inflammation / prevention & control; Inflammation Mediators / metabolism; Intracellular Signaling Peptides and Proteins / antagonists & inhibitors; Leukocyte Elastase / pharmacology; Lung / drug effects; Lung / physiopathology; Male; Membrane Proteins / antagonists & inhibitors; Metaplasia / chemically induced; Methacholine Chloride / administration & dosage; Mice; Mice, Inbred BALB C; Mucin 5AC / antagonists & inhibitors; Mucin 5AC / metabolism; Myristoylated Alanine-Rich C Kinase Substrate; Peptide Fragments / pharmacology; Respiratory Hypersensitivity / chemically induced; Respiratory Hypersensitivity / physiopathology; Respiratory System / drug effects; Respiratory System / metabolism; Serotonin
TL;DR: The concept that even in airway epithelia remodeled with goblet cell metaplasia and in a state of mucin hypersecretion, exogenous attenuation of function of MARCKS protein via the MANS peptide decreases airway mucin secretion, inflammation, and hyperreactivity is supported. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

MARCKS and Related Chaperones Bind to Unconventional Myosin V Isoforms in Airway Epithelial Cells

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 43(2), 131–136.

By: K. Lin n, S. Fang n, J. Park n, A. Crews n & K. Adler n

author keywords: airway; mucin; MARCKS; chaperones; myosin
MeSH headings : Bronchi / pathology; Epithelial Cells / cytology; Gene Expression Regulation; HSP70 Heat-Shock Proteins / chemistry; Humans; Intracellular Signaling Peptides and Proteins / metabolism; Membrane Proteins / metabolism; Models, Biological; Molecular Chaperones; Mucins / metabolism; Myosin Heavy Chains / chemistry; Myosin Type V / chemistry; Myristoylated Alanine-Rich C Kinase Substrate; Protein Binding; Protein Isoforms; Tetradecanoylphorbol Acetate / chemistry; Transfection
TL;DR: It is reported that myristoylated alanine-rich C kinase substrate (MARCKS) also interacts with unconventional myosin isoforms within these cells, and further molecular interactions between MARCKS and these chaperones/cytoskeletal proteins are elucidated. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Interferon Regulatory Factor 3 Attenuates Reovirus Myocarditis and Contributes to Viral Clearance

JOURNAL OF VIROLOGY, 84(14), 6900–6908.

MeSH headings : Animals; Animals, Newborn; Cells, Cultured; Humans; Immunity; Interferon Regulatory Factor-3 / genetics; Interferon Regulatory Factor-3 / metabolism; Interferon-beta / genetics; Interferon-beta / metabolism; Liver / pathology; Liver / virology; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocarditis / immunology; Myocarditis / pathology; Myocarditis / virology; Myocytes, Cardiac / pathology; Myocytes, Cardiac / virology; Reoviridae / metabolism; Reoviridae / pathogenicity; Reoviridae Infections / immunology; Reoviridae Infections / pathology; Reoviridae Infections / virology; Spleen / pathology; Spleen / virology; Survival Rate; Tissue Distribution
TL;DR: Cellular and humoral immune responses were equivalent in wild-type and IRF-3−/− animals, suggesting that IRf-3 functions independently of the adaptive immune response to enhance reovirus clearance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

In vivo depletion of CD4(+)CD25(hi) regulatory T cells is associated with improved antiviral responses in cats chronically infected with feline immunodeficiency virus

VIROLOGY, 403(2), 163–172.

author keywords: Feline immunodeficiency virus; HIV-1; Lentivirus; Regulatory T cell; Immunosuppression; Monoclonal antibody
MeSH headings : Animals; Antibodies, Monoclonal / administration & dosage; Antibodies, Viral / blood; CD4 Antigens / analysis; Cat Diseases / immunology; Cat Diseases / virology; Cats; Female; Immunodeficiency Virus, Feline / immunology; Interleukin-2 Receptor alpha Subunit / analysis; Lentivirus Infections / immunology; Lentivirus Infections / veterinary; Lymphocyte Depletion; T-Lymphocytes, Regulatory / chemistry; T-Lymphocytes, Regulatory / immunology
TL;DR: It is proposed that short-term in vivo Treg cell depletion during chronic HIV-1 infection could provide a window of opportunity for therapeutic vaccination in individuals with controlled viral replication. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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