Works Published in 2019
Displaying works 101 - 120 of 147 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2019 journal article
Sequential Immunofluorescence and Immunohistochemistry on Cryosectioned Zebrafish Embryos
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, (147).
author keywords: Biology; Issue 147; Zebrafish; embryos; immunohistochemistry; immunofluorescence; colocalization; intercellular interaction
MeSH headings : Animals; Cryoultramicrotomy; Embryo, Nonmammalian / anatomy & histology; Immunohistochemistry; Zebrafish / anatomy & histology; Zebrafish / embryology
TL;DR:
The purpose of the method described herein is to perform sequential immunofluorescence and/or immunohistochemistry on individual cryosections derived from early-stage zebrafish embryos to achieve precise identification of protein expression at the single-cell level.
(via Semantic Scholar)
www.jove.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 24, 2019
2019 journal article
A missense variant in the titin gene in Doberman pinscher dogs with familial dilated cardiomyopathy and sudden cardiac death
HUMAN GENETICS, 138(5), 515–524.
MeSH headings : Amino Acid Sequence; Animals; Base Sequence; Cardiomyopathy, Dilated / genetics; Cardiomyopathy, Dilated / veterinary; Connectin / genetics; Death, Sudden, Cardiac / etiology; Death, Sudden, Cardiac / veterinary; Disease Models, Animal; Dogs; Female; Genetic Predisposition to Disease / genetics; Male; Mutation, Missense / genetics; Protein Kinases / genetics; Whole Genome Sequencing
TL;DR:
The dog provides a large animal model of familial dilated cardiomyopathy and is an excellent model to improve the understanding of the genotypic phenotypic relationships, penetrance, expression and the pathophysiology of variants in the titin gene.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 17, 2019
2019 journal article
Quantifying the relationship between human Lyme disease and Borrelia burgdorferi exposure in domestic dogs
GEOSPATIAL HEALTH, 14(1), 111–120.
author keywords: Lyme disease; Canine sentinel; Borrelia burgdorferi; USA
MeSH headings : Animals; Bayes Theorem; Borrelia burgdorferi; Dog Diseases / epidemiology; Dogs; Humans; Incidence; Lyme Disease / epidemiology; Pets / microbiology; Seroepidemiologic Studies; United States / epidemiology
TL;DR:
Bayesian statistical methods were used to fit a spatio-temporal spline regression model to estimate the relationship between human LD incidence and canine seroprevalence, and a strong non-linear monotonically increasing association was found.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 4, 2019
2019 journal article
Cardiac Leiomyosarcoma in a Cat Presenting for Bilateral Renal Neoplasia
JOURNAL OF COMPARATIVE PATHOLOGY, 168, 19–24.
author keywords: cardiac neoplasia; cat; immunohistochemistry; leiomyosarcoma
MeSH headings : Animals; Cat Diseases / pathology; Cats; Female; Heart Neoplasms / veterinary; Kidney Neoplasms / veterinary; Leiomyosarcoma / veterinary
TL;DR:
A 10-year-old neutered female domestic longhair cat was presented to a tertiary care veterinary hospital for evaluation of a right renal mass that was identified incidentally on abdominal radiographs as a sarcoma based on fine needle aspiration cytology, and diagnosed with cardiac leiomyosarcoma with pulmonary and bilateral renal metastasis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: June 4, 2019
2019 journal article
Perception of Cats: Assessing the Differences Between Videos and Still Pictures on Adoptability and Associated Characteristics
FRONTIERS IN VETERINARY SCIENCE, 6.
author keywords: feline; adoption; personality; photograph; video
TL;DR:
There is an advantage of videos over pictures in perceived adoptability, as determined by response to the question “how likely would you be to adopt this cat,” but this difference is small and likely does not justify additional resources.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 28, 2019
2019 journal article
US Veterinarians' Knowledge, Experience, and Perception Regarding the Use of Cannabidiol for Canine Medical Conditions
FRONTIERS IN VETERINARY SCIENCE, 5.
author keywords: cannabidiol; canine; legal status; veterinary use; client communication
TL;DR:
Overall, CBD was most frequently discussed as a potential treatment for pain management, anxiety and seizures, and Veterinarians practicing in states with legalized recreational marijuana were more likely to advise their clients and recommend the use of CBD, while there was no difference in the likelihood of prescribing CBD products.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: May 28, 2019
2019 journal article
Medical Updates and Appointment Confirmations: Pet Owners' Perceptions of Current Practices and Preferences
FRONTIERS IN VETERINARY SCIENCE, 6.
author keywords: veterinarian-client communication; text messages; telemedicine; client preferences; medical updates; telehealth; millennials
TL;DR:
There were differences in both frequency and modality between what pet owners currently encounter and what they would prefer, and few pet owners receive medical updates or appointment confirmations via text, when a significant portion would prefer this mode of communication.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 28, 2019
2019 journal article
International Society for Companion Animal Infectious Diseases (ISCAID) guidelines for the diagnosis and management of bacterial urinary tract infections in dogs and cats
VETERINARY JOURNAL, 247, 8–25.
author keywords: Antimicrobials; Cystitis; Prostatitis; Pyelonephritis; Antimicrobial stewardship
MeSH headings : Animals; Bacterial Infections / diagnostic imaging; Bacterial Infections / drug therapy; Bacterial Infections / therapy; Bacterial Infections / veterinary; Cat Diseases / diagnosis; Cat Diseases / therapy; Cats; Dog Diseases / diagnosis; Dog Diseases / therapy; Dogs; Pets; Urinary Tract Infections / diagnosis; Urinary Tract Infections / therapy; Urinary Tract Infections / veterinary
TL;DR:
This document is a revision and expansion on the 2011 Antimicrobial Use Guidelines for Treatment of Urinary Tract Disease in Dogs and Cats, providing recommendations for diagnosis and management of sporadic bacterial cystitis, recurrent bacterial cyStitis, pyelonephritis, bacterial prostatitis, and subclinical bacteriuria.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: May 20, 2019
2019 article
Stifle joint osteoarthritis at the time of diagnosis of cranial cruciate ligament injury is higher in Boxers and in dogs weighing more than 35 kilograms
VETERINARY RADIOLOGY & ULTRASOUND, Vol. 60, pp. 280–288.
author keywords: cranial cruciate ligament; dog; osteoarthritis; osteophytes
MeSH headings : Animals; Anterior Cruciate Ligament Injuries / diagnosis; Anterior Cruciate Ligament Injuries / diagnostic imaging; Anterior Cruciate Ligament Injuries / veterinary; Body Weight; Dog Diseases / diagnosis; Dog Diseases / diagnostic imaging; Dog Diseases / epidemiology; Dogs; Female; Male; Osteoarthritis / diagnosis; Osteoarthritis / diagnostic imaging; Osteoarthritis / veterinary; Prevalence; Radiography / veterinary; Retrospective Studies; Species Specificity; Stifle
TL;DR:
It is concluded that dogs have a consistent distribution pattern of OA within the stifle joint after CCL injury and Boxers had more severe OA than the other breeds evaluated in the study.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 20, 2019
2019 journal article
Neuromedin B Induces Acute Itch in Mice via the Activation of Peripheral Sensory Neurons
ACTA DERMATO-VENEREOLOGICA, 99(6), 587–593.
author keywords: acute itch; dorsal root ganglia; mast cells; neuromedin B; allergic dermatitis.
MeSH headings : Animals; Calcium / metabolism; Cell Degranulation; Cells, Cultured; Dermatitis, Allergic Contact / etiology; Female; Ganglia, Spinal / cytology; Ganglia, Spinal / metabolism; Gene Expression; Indoles / pharmacology; Injections, Intradermal; Macaca mulatta; Male; Mast Cells / metabolism; Mast Cells / physiology; Mice; Neurokinin B / administration & dosage; Neurokinin B / analogs & derivatives; Pruritus / chemically induced; Pyridines / pharmacology; RNA, Messenger / metabolism; Receptors, Bombesin / antagonists & inhibitors; Receptors, Bombesin / genetics; Receptors, Bombesin / metabolism; Sensory Receptor Cells / physiology; Single-Cell Analysis; Toluene 2,4-Diisocyanate
TL;DR:
In vitro real time PCR analysis for neuromedin B and its receptor expression in murine mast cells and dorsal root ganglia as well as functional calcium imaging in the ganglia found that the peripheral signal is likely transmitted through the activation of dorsalRoot ganglia.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: May 20, 2019
2019 journal article
Cellular Plasticity of Defa4(Cre)-Expressing Paneth Cells in Response to Notch Activation and Intestinal Injury
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 7(3), 533–554.
author keywords: Defensin; Paneth Cell; Intestinal Stem Cells; Regeneration; Enteroid; Notch; Chemotherapy
MeSH headings : ADAM10 Protein / metabolism; Adenoma / pathology; Adenomatous Polyposis Coli Protein / metabolism; Alleles; Animals; Cell Dedifferentiation; Cell Lineage; Cell Plasticity; Clone Cells; Doxorubicin; Gene Deletion; Homeostasis; Hyperplasia; Integrases / metabolism; Intestines / injuries; Intestines / pathology; Mice; Mitosis; Multipotent Stem Cells / metabolism; Organoids / growth & development; Organoids / pathology; Paneth Cells / metabolism; Receptors, Notch / metabolism; Regeneration; alpha-Defensins / metabolism
TL;DR:
The studies have shown that Defa4Cre-expressing Paneth cells possess cellular plasticity, can dedifferentiate into multipotent stem cells upon Notch activation, and can contribute to intestinal regeneration in an acute injury model.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 6, 2019
2019 journal article
Maternal pre-pregnancy obesity, offspring cord blood DNA methylation, and offspring cardiometabolic health in early childhood: an epigenome-wide association study
EPIGENETICS, 14(4), 325–340.
author keywords: DNA methylation; epigenome-wide association study; maternal obesity; offspring body mass index; offspring blood pressure; cardiometabolic health; ALSPAC; NEST
MeSH headings : Adult; Blood Pressure; Cardiovascular Diseases / epidemiology; Cardiovascular Diseases / genetics; Child; Child, Preschool; DNA Methylation; Epigenesis, Genetic; Epigenomics; Female; Genome-Wide Association Study; Humans; Infant, Newborn / blood; Infant, Newborn / growth & development; Male; Membrane Transport Proteins / genetics; Metabolic Syndrome / epidemiology; Metabolic Syndrome / genetics; Obesity / epidemiology; Obesity / genetics
TL;DR:
Findings suggest sex-specific effects at CpG sites of the TAPBP gene were associated with BMI z-score and systolic BP percentile in female and syStolic and diastolicBP percentile in male offspring, which, if causal, may explain observed sex- specific effects of maternal obesity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: April 29, 2019
2019 journal article
Are Geckos Paratenic Hosts for Caribbean Island Acanthocephalans? Evidence from Gonatodes antillensis and a Global Review of Squamate Reptiles Acting as Transport Hosts
BULLETIN OF THE PEABODY MUSEUM OF NATURAL HISTORY, 60(1), 55–79.
author keywords: Acanthocephala; intestinal helminths; cats; parasite; trophic transmission; mammals; birds; host-parasite interactions; vector species
TL;DR:
Evidence is found that the ability of squamate reptiles to act as transport hosts is a pervasive feature across their Tree of Life, suggesting that these animals may serve as important vectors for transporting parasites between intermediate and definitive hosts.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: April 29, 2019
2019 journal article
Enrofloxacin Pharmacokinetics and Sampling Techniques in California Sea Hares (Aplysia californica)
JOURNAL OF THE AMERICAN ASSOCIATION FOR LABORATORY ANIMAL SCIENCE, 58(2), 231–234.
MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / pharmacokinetics; Aplysia / metabolism; Chromatography, High Pressure Liquid; Enrofloxacin / administration & dosage; Enrofloxacin / pharmacokinetics; Laboratory Animal Science
TL;DR:
Hemocoel injection appears to be an effective way to administer enrofloxacin to Aplysia and reach clinically relevant concentrations, and reached therapeutic target concentrations in A. californica when dosed according to the regimen described in the current report.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 22, 2019
2019 journal article
IMMERSION IN TRICAINE METHANESULFONATE (MS-222) IS NOT SUFFICIENT FOR EUTHANASIA OF SMOKEY JUNGLE FROGS (LEPTODACTYLUS PENTADACTYLUS)
JOURNAL OF ZOO AND WILDLIFE MEDICINE, 50(1), 89–95.
author keywords: Animal welfare; Euthanasia; Leptodactylus petuadactylus; MS-222; Smokey Jungle Frog; Tricaine methanesulfonate
MeSH headings : Aminobenzoates / therapeutic use; Anesthetics / therapeutic use; Animals; Anura / physiology; Dose-Response Relationship, Drug; Euthanasia, Animal / methods; Immersion
TL;DR:
Although death was achieved in 17 of 18 frogs, given the repeated events of regained consciousness, MS-222 immersion when used at concentrations ≤10 g/L did not result in rapid and distress-free death and is not sufficient for humane euthanasia in this species.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: April 22, 2019
2019 journal article
2-PHENOXYETHANOL (2-PE) AND TRICAINE METHANESULFONATE (MS-222) IMMERSION ANESTHESIA OF AMERICAN HORSESHOE CRABS (LIMULUS POLYPHEMUS)
JOURNAL OF ZOO AND WILDLIFE MEDICINE, 50(1), 96–106.
MeSH headings : Aminobenzoates / adverse effects; Anesthesia / methods; Anesthesia / veterinary; Anesthetics / adverse effects; Animals; Ethylene Glycols / adverse effects; Female; Horseshoe Crabs / drug effects; Horseshoe Crabs / physiology; Immersion; Male; North Carolina; Random Allocation
TL;DR:
2-PE provided a subjectively more reliable and smoother anesthesia compared to MS-222, and provided effective anesthesia with clinically useful induction and recovery times.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: April 22, 2019
2019 journal article
Morphometric analysis of spinal cord termination in Cavalier King Charles Spaniels
JOURNAL OF VETERINARY INTERNAL MEDICINE, 33(2), 717–725.
author keywords: conus medullaris; dural sac; filum terminate; syringomyelia
MeSH headings : Animals; Dog Diseases / diagnostic imaging; Dogs; Dura Mater / abnormalities; Female; Magnetic Resonance Imaging / veterinary; Male; Neural Tube Defects / diagnostic imaging; Neural Tube Defects / veterinary; Reproducibility of Results; Retrospective Studies; Spinal Cord / abnormalities; Syringomyelia / diagnostic imaging; Syringomyelia / veterinary
TL;DR:
The relationship between TL SM and possible spinal cord tethering because of a more caudal dural sac termination should be investigated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: April 22, 2019
2019 review
Language Consideration and Methodological Transparency in "Systematic" Reviews of Animal Toxicity Studies
[Review of ]. INTERNATIONAL JOURNAL OF TOXICOLOGY, 38(2), 135–145.
author keywords: toxicology; translation; foreign languages; publications; systematic review methodology; authorship
MeSH headings : Animals; Authorship; Language; Meta-Analysis as Topic; Research Design; Research Support as Topic; Systematic Reviews as Topic; Toxicity Tests
TL;DR:
Neither the study type, grant funding, nor first author country of affiliation was associated with an increased consideration of NEL, and study quality reporting was more common in SRs that considered multiple languages.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: April 22, 2019
2019 journal article
Exosome proteomic analyses identify inflammatory phenotype and novel biomarkers in African American prostate cancer patients
CANCER MEDICINE, 8(3), 1110–1123.
author keywords: biomarker; exosomes; health disparity; inflammation; prostate cancer
MeSH headings : Black or African American; Biomarkers, Tumor; Biopsy; Calcium / metabolism; Cell Line, Tumor; Chromatography, Liquid; Exosomes / metabolism; Exosomes / ultrastructure; Filamins / metabolism; Healthcare Disparities; Humans; Immunohistochemistry; Inflammation Mediators; Macrophages / metabolism; Male; Molecular Imaging; Neurons / metabolism; Phenotype; Prostatic Neoplasms / epidemiology; Prostatic Neoplasms / metabolism; Proteome; Proteomics / methods; Tandem Mass Spectrometry; White People
TL;DR:
Results support the usefulness of serum exosomes to noninvasively detect inflammatory phenotype and to discover novel biomarkers associated with PCa in African American men.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: April 9, 2019
2019 journal article
Antibody-Armed Platelets for the Regenerative Targeting of Endogenous Stem Cells
NANO LETTERS, 19(3), 1883–1891.
author keywords: Myocardium infarction; platelets; endogenous stem cells; antibodies
MeSH headings : Animals; Antigens, CD34 / immunology; Blood Platelets / chemistry; Blood Platelets / immunology; Cell- and Tissue-Based Therapy; Disease Models, Animal; Heart Injuries / genetics; Heart Injuries / pathology; Heart Injuries / therapy; Humans; Mice; Myocardial Infarction / pathology; Myocardial Infarction / therapy; Myocardium / immunology; Myocardium / pathology; Stem Cells / immunology; Stem Cells / metabolism
TL;DR:
Taking advantage of the natural infarct-homing ability of platelets, CD34 antibody-linked platelets (P-CD34) are engineered to capture circulating CD34-positive endogenous stem cells and direct them to the injured heart for effective heart repair.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: April 2, 2019
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