Works Published in 2019
Displaying works 161 - 180 of 215 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2019 journal article
Challenges in a Technology-Based Cancer Pain Management Program Among Asian American Breast Cancer Survivors
CIN-COMPUTERS INFORMATICS NURSING, 37(5), 243–249.
author keywords: Asian American; Breast cancer survivors; Intervention; Issues; Racial; ethnic minority; Technology
MeSH headings : Asian / psychology; Asian / statistics & numerical data; Breast Neoplasms / complications; Breast Neoplasms / psychology; Cancer Survivors / psychology; Cancer Survivors / statistics & numerical data; Culturally Competent Care / methods; Female; Humans; Internet; Middle Aged; Pain Management / methods; Pain Management / trends; Pilot Projects; Social Media / trends
TL;DR:
The challenges faced during a pilot study that tested a technology- based cancer pain management program among Asian American survivors of breast cancer are discussed and directions for future technology-based interventions for racial and ethnic minorities are provided.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 4, 2019
2019 journal article
Microfabricated blood vessels for modeling the vascular transport barrier
NATURE PROTOCOLS, 14(5), 1425–1454.
MeSH headings : Capillary Permeability / physiology; Cell Culture Techniques / instrumentation; Cells, Cultured; Endothelial Cells / cytology; Equipment Design; Humans; Microfluidic Analytical Techniques / instrumentation; Microvessels / cytology; Microvessels / physiology; Models, Cardiovascular; Stromal Cells / cytology; Tissue Engineering / instrumentation
TL;DR:
This protocol describes how to design and fabricate the silicon hEMV device master molds and apply calibrated fluid shear stress to hEMVs, and how to assess vascular barrier function and perform immunofluorescence imaging.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 4, 2019
2019 journal article
Fabrication of Hollow Metal Microneedle Arrays Using a Molding and Electroplating Method
MRS ADVANCES, 4(24), 1417–1426.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 4, 2019
2019 journal article
Engineering Polymer-Binding Bispecific Antibodies for Enhanced Pretargeted Delivery of Nanoparticles to Mucus-Covered Epithelium
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 58(17), 5604–5608.
author keywords: antibodies; drug delivery; mucus; nanoparticles; PEGylation
MeSH headings : Antibodies, Bispecific / metabolism; Humans; Nanoparticles / metabolism; Polymers / metabolism
TL;DR:
This work explored a two-step "pretargeting" approach through engineering a bispecific antibody that binds both cell-surface ICAM-1 and polyethylene glycol (PEG) on the surface of nanoparticles, thereby effectively decoupling cell targeting from particle design and formulation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 4, 2019
2019 journal article
Prediction of Individual Finger Forces Based on Decoded Motoneuron Activities
ANNALS OF BIOMEDICAL ENGINEERING, 47(6), 1357–1368.
author keywords: EMG signal processing; Motor unit decomposition; Finger force; Hand function; Muscle activity
MeSH headings : Adult; Computer Simulation; Electromyography; Female; Fingers / innervation; Fingers / physiology; Humans; Male; Models, Neurological; Motor Neurons / physiology; Young Adult
TL;DR:
The experimental results indicate that the neural drive estimation based on motoneuron firing activities can be used as a reliable neural-machine interface signal involving individual fingers, however, real-time implementation of this approach is needed for future clinical translation.
(via Semantic Scholar)
Source: Web Of Science
Added: May 28, 2019
2019 journal article
Decreasing menopausal symptoms of Asian American breast cancer survivors through a technology-based information and coaching/support program
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 26(4), 373–382.
author keywords: Asian American; Breast cancer; Menopause; Survivors; Symptoms; Technology-based intervention
MeSH headings : Asian; Attitude to Health; Breast Neoplasms; Cancer Survivors; Female; Humans; Internet; Menopause / psychology; Middle Aged; Self Efficacy; Social Support
TL;DR:
The program was effective in alleviating menopausal symptoms of Asian American breast cancer survivors and theory-driven and culturally tailored intervention program aimed to provide information and coaching/support using computers and mobile devices.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 28, 2019
2019 journal article
Interference Removal From Electromyography Based on Independent Component Analysis
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING, 27(5), 887–894.
author keywords: Biosignal processing; independent component analysis; motion artifacts; noise reduction; power line noise
MeSH headings : Adult; Algorithms; Artifacts; Electromyography / methods; Electromyography / statistics & numerical data; Female; Fingers / innervation; Fingers / physiology; Hand / innervation; Hand / physiology; Humans; Male; Motor Neurons / physiology; Muscle Fibers, Skeletal / physiology; Muscle, Skeletal / physiology; Principal Component Analysis; Signal Processing, Computer-Assisted; Signal-To-Noise Ratio; Young Adult
TL;DR:
The method showed a minimal distortion of the denoised EMG amplitude and frequency and a higher yield of decomposed motor units and can benefit macro level EMG analysis and micro level motor unit analysis.
(via Semantic Scholar)
Source: Web Of Science
Added: May 28, 2019
2019 journal article
Toxicity and photosensitizing assessment of gelatin methacryloyl-based hydrogels photoinitiated with lithium phenyl-2,4,6-trimethylbenzoylphosphinate in human primary renal proximal tubule epithelial cells
BIOINTERPHASES, 14(2).
MeSH headings : Biocompatible Materials / chemical synthesis; Biocompatible Materials / toxicity; Cell Survival / drug effects; Cells, Cultured; Elasticity; Epithelial Cells / drug effects; Gelatin / chemistry; Gelatin / toxicity; Humans; Hydrogels / chemical synthesis; Hydrogels / toxicity; Lithium / toxicity; Materials Testing; Phosphinic Acids / toxicity; Polyhydroxyethyl Methacrylate / chemical synthesis; Polyhydroxyethyl Methacrylate / toxicity; Tissue Scaffolds
TL;DR:
Complete cross-linking of all formulations decreased photocatalytic activity while maintaining predictable final elastic moduli, and differences in cytotoxicity evaluation determined from the two viability assays imply cell membrane damage and should be investigated further.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 20, 2019
2019 journal article
An introduction to a new direct testing method for characterizing pressure in compression fabrics
JOURNAL OF THE TEXTILE INSTITUTE, 110(6), 822–831.
author keywords: Compression medical textiles; compression garments; interface pressure; body measurement; sensor measuring
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
7. Affordable and Clean Energy
(OpenAlex)
Source: Web Of Science
Added: May 20, 2019
2019 journal article
Robust antigen-specific tuning of the nanoscale barrier properties of biogels using matrix-associating IgG and IgM antibodies
ACTA BIOMATERIALIA, 89, 95–103.
author keywords: Basement membrane; Extracellular matrix; Antibodies; Laminin; Particle tracking; PEG
MeSH headings : Animals; Antigens / chemistry; Collagen / chemistry; Drug Combinations; Hydrogels / chemistry; Immunoglobulin G / chemistry; Immunoglobulin M / chemistry; Laminin / chemistry; Membranes, Artificial; Nanoparticles / chemistry; Proteoglycans / chemistry
TL;DR:
A new approach is offered, based on weakly adhesive third-party molecular anchors, that allow for a variety of foreign entities to be trapped within a biogel simultaneously with exceptional potency and molecular specificity, without perturbing the bulk properties of the biogels.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 20, 2019
2019 journal article
A Dual-Bioresponsive Drug-Delivery Depot for Combination of Epigenetic Modulation and Immune Checkpoint Blockade
ADVANCED MATERIALS, 31(17).
author keywords: bioresponsive materials; drug delivery; epigenetic modulation; immune checkpoint blockade; immunotherapy
MeSH headings : Animals; Antibodies, Monoclonal / pharmacology; Antibodies, Monoclonal, Humanized; Antineoplastic Agents / chemical synthesis; Antineoplastic Agents / pharmacology; Calcium Carbonate / chemistry; Cell Line, Tumor; Cytidine / analogs & derivatives; Cytidine / pharmacology; Drug Delivery Systems / methods; Drug Liberation; Drug Therapy, Combination / methods; Humans; Hydrogen-Ion Concentration; Immunosuppressive Agents / chemistry; Immunosuppressive Agents / pharmacology; Immunotherapy / methods; Melanoma / drug therapy; Nanoparticles / chemistry; Programmed Cell Death 1 Receptor / metabolism; Reactive Oxygen Species / metabolism; Tumor Microenvironment / drug effects
TL;DR:
It is demonstrated that this combination therapy increases the immunogenicity of cancer cells, and also plays roles in reversing immunosuppressive TME, which contributes to inhibiting the tumor growth and prolonging the survival time of B16F10‐melanoma‐bearing mice.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 13, 2019
2019 journal article
Molecular transport through primary human small intestinal monolayers by culture on a collagen scaffold with a gradient of chemical cross-linking
JOURNAL OF BIOLOGICAL ENGINEERING, 13.
author keywords: Intestinal transport; Stiffness; Extracellular matrix; Small intestine
TL;DR:
The results of this comparison highlight the need to create in vitro intestinal transport platforms whose characteristics mimic the in vivo lamina propria in order to accurately recapitulate epithelial function.
(via Semantic Scholar)
jbioleng.biomedcentral.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 13, 2019
2019 journal article
Characterization of glass frit capillary pumps for microfluidic devices
MICROFLUIDICS AND NANOFLUIDICS, 23(5).
author keywords: Porous; Glass; Capillary forces; Pump; Microfluidic; Point-of-care
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 6, 2019
2019 journal article
Characterization of a Multiple-Scan-Rate Voltammetric Waveform for Real-Time Detection of Met-Enkephalin
ACS CHEMICAL NEUROSCIENCE, 10(4), 2022–2032.
author keywords: carbon fiber; opioid; chromaffin cell; dopamine; cyclic voltammetry; microelectrode; FSCV
MeSH headings : Adrenal Glands / chemistry; Adrenal Glands / metabolism; Animals; Electrochemical Techniques / methods; Enkephalin, Methionine / analysis; Enkephalin, Methionine / metabolism; Male; Microinjections / methods; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Substantia Nigra / chemistry; Substantia Nigra / metabolism
TL;DR:
This work evaluated the waveform parameters to increase sensitivity to methionine-enkephalin (M-ENK), an endogenous opioid neuropeptide implicated in pain, stress, and reward circuits and demonstrates how voltammetric waveforms can be customized to enhance detection of specific target analytes, broadly speaking.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: May 6, 2019
2019 journal article
Enhanced local cancer therapy using a CA4P and CDDP co-loaded polypeptide gel depot
BIOMATERIALS SCIENCE, 7(3), 860–866.
MeSH headings : Animals; Cell Line, Tumor; Cell Survival / drug effects; Cisplatin / chemistry; Cisplatin / metabolism; Cisplatin / therapeutic use; Cisplatin / toxicity; Colonic Neoplasms / drug therapy; Colonic Neoplasms / pathology; Drug Liberation; Female; Humans; Hydrogels / chemical synthesis; Hydrogels / chemistry; Mice, Inbred BALB C; Peptides / chemistry; Polymers / chemical synthesis; Polymers / chemistry; Stilbenes / chemistry; Stilbenes / metabolism; Stilbenes / therapeutic use; Stilbenes / toxicity; Transplantation, Heterologous; Tumor Microenvironment / drug effects
TL;DR:
The results indicated that this material possessed concentration-dependent thermogelling properties and tunable in vivo biodegradability and showed the highest antitumor efficacy compared with the other experimental groups after peritumoral injection toward C26 tumor bearing mice.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: April 22, 2019
2019 journal article
Industrial-scale fabrication of an osteogenic and antibacterial PLA/silver-loaded calcium phosphate composite with significantly reduced cytotoxicity
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 107(4), 900–910.
author keywords: industrial-scale fabrication; multifunctional scaffold; osteogenic; antibacterial; reduced cytotoxicity
MeSH headings : Adipose Tissue / cytology; Adipose Tissue / metabolism; Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Calcium Phosphates / chemistry; Calcium Phosphates / pharmacology; Cell Differentiation / drug effects; Escherichia coli / growth & development; Humans; Osteogenesis / drug effects; Polyesters / chemical synthesis; Polyesters / chemistry; Polyesters / pharmacology; Silver / chemistry; Silver / pharmacology; Staphylococcus aureus / growth & development; Stem Cells / cytology; Stem Cells / metabolism; Tissue Scaffolds / chemistry
TL;DR:
The results of this study indicate a promising alternative approach to produce multifunctional scaffolds at industrial-scale with higher throughput, lower cost, and enhanced reproducibility.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: April 22, 2019
2019 review
A qualitative review of the design thinking framework in health professions education
[Review of ]. BMC MEDICAL EDUCATION, 19.
author keywords: Design thinking; Curriculum development; Creativity; Problem solving; Innovation
MeSH headings : Curriculum; Health Occupations / education; Health Personnel / education; Health Personnel / psychology; Humans; Problem Solving; Problem-Based Learning; Qualitative Research; Thinking
TL;DR:
The extent to which design thinking is taught to students as a skill-based tool to prepare students for problem solving in complex healthcare environments and the use of design thinking to create, implement, and refine health professions curricula and educational programs is reviewed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(OpenAlex)
Source: Web Of Science
Added: April 22, 2019
2019 journal article
Planar Hall effect and anisotropic magnetoresistance in semiconducting and conducting oxide thin films
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING, 125(5).
Source: Web Of Science
Added: April 22, 2019
2019 journal article
Illuminating the Numbers: Integrating Mathematical Models to Optimize Photomedicine Dosimetry and Combination Therapies
FRONTIERS IN PHYSICS, 7.
author keywords: photomedicine; mathematical oncology; photodynamic therapy; immunotherapy; computational modeling; combination therapy; cancer
TL;DR:
The utility of mathematical and computational approaches to guide adaptive therapy, and how mathematical models might be further developed and integrated as a novel methodology to guide precision photomedicine are foreseen.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: April 15, 2019
2019 journal article
Evidence for Aryl hydrocarbon Receptor-Mediated Inhibition of Osteoblast Differentiation in Human Mesenchymal Stem Cells
TOXICOLOGICAL SCIENCES, 167(1), 145–156.
author keywords: aryl hydrocarbon receptor; 2,3,7,8-tetrachlorodibenzo-p-dioxin; TCDD; mesenchymal stem cell; osteoblast differentiation; skeletal toxicity; bone toxicity
MeSH headings : Basic Helix-Loop-Helix Transcription Factors / agonists; Cell Differentiation / drug effects; Fibroblast Growth Factor 9 / genetics; Fibroblast Growth Factors / genetics; Humans; Ligands; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / drug effects; Mesenchymal Stem Cells / metabolism; Osteoblasts / cytology; Osteoblasts / drug effects; Osteoblasts / metabolism; Osteogenesis / drug effects; Osteogenesis / genetics; Polychlorinated Dibenzodioxins / toxicity; Receptors, Aryl Hydrocarbon / agonists; Up-Regulation
TL;DR:
Experimental evidence from this study suggests that AhR transactivation likely attenuates osteoblast differentiation in multipotent hBMSCs, and underscores the use of primary human MSCs to evaluate osteoinductive or osteotoxic potential of chemical and pharmacologic agents in vitro.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: April 15, 2019
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