Works Published in 2016
Displaying works 61 - 80 of 117 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2016 journal article
An imaging investigation of in situ uroliths in hospitalized cats in New Zealand and in the United States
VETERINARY MEDICINE AND SCIENCE, 2(4), 255–265.
Contributors: P. Wightman *, K. Hill *, E. Cohen n , J. Bridges *, C. Bolwell *, J. French*, B. Adler*, R. Green*
author keywords: feline; imaging; prevalence; urolith; urolithiasis
TL;DR:
The prevalence of uroliths in the upper tract or lower tract was low in the New Zealand cohort compared to that of cats in the USA cohort, irrespective of age category, and may be important when evaluating risk factors for feline urolithiasis.
(via Semantic Scholar)
onlinelibrary.wiley.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2016 journal article
Troubleshooting hypothermia and hyperthermia brrrr is bad too!
Questions and Answers in Small Animal Anesthesia, 147–153.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Topically applied manganese-porphyrins BMX-001 and BMX-010 display a significant anti-inflammatory response in a mouse model of allergic dermatitis
ARCHIVES OF DERMATOLOGICAL RESEARCH, 308(10), 711–721.
author keywords: Superoxide dismutase mimics; BMX-010; BMX-001; Allergic dermatitis; Mice
MeSH headings : Administration, Cutaneous; Administration, Oral; Animals; Cell Line; Dendritic Cells / drug effects; Dendritic Cells / metabolism; Dermatitis, Allergic Contact / drug therapy; Disease Models, Animal; Ear; Female; Humans; Infant, Newborn; Inflammation / drug therapy; Inflammation / metabolism; Interleukin-1beta / metabolism; Interleukin-4 / metabolism; Keratinocytes / drug effects; Keratinocytes / metabolism; Metalloporphyrins / administration & dosage; Metalloporphyrins / therapeutic use; Mice; Mice, Inbred BALB C; Pruritus / drug therapy; Skin / drug effects; Skin / metabolism; Skin Cream; Superoxide Dismutase / metabolism; Toluene 2,4-Diisocyanate / toxicity; p-Methoxy-N-methylphenethylamine / toxicity
TL;DR:
Topical treatment with BMX cream resulted in a significant decrease in scratching behaviour in the compound 48/80 model, but not in the TDI model, and interestingly, the concentration of the cytokines IL-1β and IL-4 in inflamed skin was reduced by 80–90 % by all treatment options.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 review
Review of Automated Microinjection Systems for Single Cells in the Embryogenesis Stage
[Review of ]. IEEE-ASME TRANSACTIONS ON MECHATRONICS, 21(5), 2391–2404.
author keywords: Automation; biological cells; control system; mechatronics; reviews
TL;DR:
A comprehensive review of the major research technologies used in automated cell microin injection and of their individual subsystems concludes that research into automated microinjection systems will focus on reducing the scale of microinject systems and developing appropriate controllers.
(via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2016 journal article
Posaconazole Pharmacokinetics in Healthy Cats after Oral and Intravenous Administration
JOURNAL OF VETERINARY INTERNAL MEDICINE, 30(5), 1703–1707.
author keywords: Bioavailability; Blastomyces; Fungal infection; Histoplasma
MeSH headings : Administration, Oral; Animals; Antifungal Agents / administration & dosage; Antifungal Agents / pharmacokinetics; Area Under Curve; Cats; Female; Half-Life; Injections, Intravenous; Male; Triazoles / administration & dosage; Triazoles / pharmacokinetics
TL;DR:
Despite low PO absorption, these data allow for simulation of PO dosage regimens that could be explored in clinical studies, and two regimens can be considered to maintain targeted trough concentrations of 0.5–0.7 μg/mL as extrapolated from studies in humans.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
Intermittent At-Home Suctioning of Esophageal Content for Prevention of Recurrent Aspiration Pneumonia in 4 Dogs with Megaesophagus
JOURNAL OF VETERINARY INTERNAL MEDICINE, 30(5), 1715–1719.
author keywords: Esophagostomy; Regurgitation
MeSH headings : Animals; Catheters, Indwelling; Dog Diseases / etiology; Dog Diseases / prevention & control; Dogs; Enteral Nutrition; Esophageal Achalasia / complications; Esophageal Achalasia / veterinary; Female; Male; Pneumonia, Aspiration / etiology; Pneumonia, Aspiration / prevention & control; Pneumonia, Aspiration / veterinary; Recurrence; Suction / methods; Survival Analysis
TL;DR:
Use of intermittent esophageal suctioning in dogs with megaesophagus that continue to regurgitate despite gastrostomy tube feedings can reduce or abolish clinical episodes of aspiration pneumonia.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
Genotype imputation in the domestic dog
MAMMALIAN GENOME, 27(9-10), 485–494.
MeSH headings : Alleles; Animals; Breeding; Computer Simulation; Dogs / genetics; Genotype; Models, Genetic; Polymorphism, Single Nucleotide; Sequence Analysis, DNA
TL;DR:
These findings demonstrate that genotype imputation from SNP array-derived data to whole genome-level genotypes is both feasible and accurate in the dog with appropriate breed overlap between the target and reference panels.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Feline onychectomy: Current practices and perceptions of veterinarians in Ontario, Canada
Canadian Veterinary Journal, 57(9), 969–975.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
External beam radiation therapy of squamous cell carcinoma in the beak of an African grey parrot (Psittacus timneh)
Journal of Avian Medicine and Surgery, 30(3), 250–256.
MeSH headings : Animals; Beak / pathology; Bird Diseases / radiotherapy; Carcinoma, Squamous Cell / radiotherapy; Carcinoma, Squamous Cell / veterinary; Male; Parrots
TL;DR:
Squamous cell carcinoma of the rhinotheca was diagnosed in a 34-year-old timneh African grey parrot with a 2-year history of beak abnormalities and died approximately 7 months after diagnosis and 4 months after cessation of radiation treatment.
(via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Clinical and diagnostic imaging features of brain herniation in dogs and cats
Journal of Veterinary Internal Medicine, 30(5), 1672–1680.
MeSH headings : Animals; Body Size; Brain / diagnostic imaging; Brain / pathology; Cat Diseases / diagnostic imaging; Cat Diseases / pathology; Cats; Dog Diseases / diagnostic imaging; Dog Diseases / pathology; Dogs; Magnetic Resonance Imaging / veterinary; Retrospective Studies
TL;DR:
Brain herniation can be quantified on MRI and more severe CTH based on TTX is associated with a worse short‐term outcome, compared with more severe foramen magnum based on FMH.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
An Inhaled Inhibitor of Myristoylated Alanine-Rich C Kinase Substrate Reverses LPS-Induced Acute Lung Injury in Mice
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 55(5), 617–622.
author keywords: myristoylated alanine-rich C kinase substrate; acute lung injury; LPS; neutrophils
MeSH headings : Acute Lung Injury / chemically induced; Acute Lung Injury / drug therapy; Aerosols / administration & dosage; Aerosols / pharmacology; Animals; Behavior, Animal; Bronchoalveolar Lavage Fluid; Cytokines / metabolism; Female; Inflammation Mediators / metabolism; Intracellular Signaling Peptides and Proteins / antagonists & inhibitors; Intracellular Signaling Peptides and Proteins / metabolism; Leukocytes / metabolism; Lipopolysaccharides; Lung / drug effects; Lung / metabolism; Lung / pathology; Membrane Proteins / antagonists & inhibitors; Membrane Proteins / metabolism; Mice, Inbred BALB C; Myristoylated Alanine-Rich C Kinase Substrate; NF-kappa B / metabolism; Peptides / administration & dosage; Peptides / pharmacology; Peptides / therapeutic use
TL;DR:
Results implicate MARCKS protein in the pathogenesis of ALI/ARDS and suggest that MARC KS-inhibitory peptide(s), delivered by inhalation, could represent a new and potent therapeutic treatment for ALi/ARDS, even if administered well after the disease process has begun.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Alternative haplotypes of antigen processing genes in zebrafish diverged early in vertebrate evolution
Proceedings of the National Academy of Sciences, 113(34), E5014–E5023.
author keywords: comparative genomics; proteasome and TAP evolution; major histocompatibility; MHC class I pathway; CG2 clonal zebrafish
MeSH headings : Animals; Antigen Presentation; Biological Evolution; Cloning, Organism; Cysteine Endopeptidases / classification; Cysteine Endopeptidases / genetics; Cysteine Endopeptidases / immunology; Genome; Haplotypes; High-Throughput Nucleotide Sequencing; Histocompatibility Antigens Class I / classification; Histocompatibility Antigens Class I / genetics; Histocompatibility Antigens Class I / immunology; Phylogeny; Proteasome Endopeptidase Complex / genetics; Proteasome Endopeptidase Complex / immunology; Protein Isoforms / classification; Protein Isoforms / genetics; Protein Isoforms / immunology; Transcriptome; Zebrafish / classification; Zebrafish / genetics; Zebrafish / immunology; Zebrafish Proteins / classification; Zebrafish Proteins / genetics; Zebrafish Proteins / immunology
TL;DR:
Comparison analysis shows that antigen processing gene diversity is far more extensive than previously realized, implying distinct immune functions and conserved roles in shaping MHC pathway evolution throughout vertebrates.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2016 journal article
Allergic inflammation is augmented via histamine H4 receptor activation: The role of natural killer cells in vitro and in vivo
JOURNAL OF DERMATOLOGICAL SCIENCE, 83(2), 106–115.
author keywords: Natural killer cells; Histamine H4 receptor; CCL17/TARC; Dermal dendritic cells; Allergic contact dermatitis
MeSH headings : Animals; Chemokine CCL17 / metabolism; Chemotaxis / drug effects; Coculture Techniques; Dendritic Cells / drug effects; Dendritic Cells / metabolism; Dermatitis, Atopic / immunology; Dermatitis, Atopic / metabolism; Disease Models, Animal; Female; Histamine / metabolism; Humans; Indoles / pharmacology; Killer Cells, Natural / drug effects; Killer Cells, Natural / metabolism; Mice; Mice, Inbred BALB C; Mice, Knockout; Ovalbumin; Piperazines / pharmacology; Pyrimidines / pharmacology; Receptors, G-Protein-Coupled / agonists; Receptors, G-Protein-Coupled / antagonists & inhibitors; Receptors, G-Protein-Coupled / genetics; Receptors, G-Protein-Coupled / metabolism; Receptors, Histamine / genetics; Receptors, Histamine / metabolism; Receptors, Histamine H4; Skin / cytology; Skin / drug effects; Skin / metabolism; Toluene 2,4-Diisocyanate / toxicity
TL;DR:
The H4R is identified as a new target controlling NK cell migration and NK cell-dendritic cell interaction in the skin during early allergic inflammation and is suggested to be beneficial in diseases like AD.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Use of RNA-seq to identify cardiac genes and gene pathways differentially expressed between dogs with and without dilated cardiomyopathy
AMERICAN JOURNAL OF VETERINARY RESEARCH, 77(7), 693–699.
MeSH headings : Animals; Cardiomyopathy, Dilated / genetics; Cardiomyopathy, Dilated / metabolism; Cardiomyopathy, Dilated / veterinary; Dog Diseases / genetics; Dog Diseases / metabolism; Dogs; Down-Regulation; Female; Gene Expression; Heart Ventricles; Male; Myocardium / metabolism; RNA / genetics; Up-Regulation
TL;DR:
Genes involved in cellular energy metabolism, especially metabolism of carbohydrates and fats, were significantly downregulated in dogs with DCM, and Expression of cardiac structural proteins was also altered in affected dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
The confounding complexity of innate immune receptors within and between teleost species
Fish & Shellfish Immunology, 53, 24–34.
author keywords: Gene content haplotype; Novel immune-type receptors; Diverse immunoglobulin domain containing proteins; Polymeric immunoglobulin receptor-like proteins; Novel immunoglobulin-like transcripts
MeSH headings : Animals; Fishes / genetics; Fishes / immunology; Genetic Variation; Genome; Immunity, Innate; Receptors, Immunologic / genetics
TL;DR:
By defining which teleost lineages encode (and do not encode) different IIir families, predictions can be made about the presence (or absence) of specific IIIR families in each teleost lineage.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2016 journal article
Single-cell transcriptional analysis of normal, aberrant, and malignant hematopoiesis in zebrafish
The Journal of Cell Biology, 213(3), 2133OIA95.
Sources: NC State University Libraries, ORCID, NC State University Libraries
Added: August 6, 2018
2016 journal article
Scanning technology selection impacts acceptability and usefulness of image-rich content
JOURNAL OF THE MEDICAL LIBRARY ASSOCIATION, 104(1), 15–23.
author keywords: Interlibrary Loans; Photographs; Image Enhancement; Image Compression; Pathology; Radiology
MeSH headings : Diagnostic Imaging / standards; Documentation / standards; Electronic Health Records / standards; Humans; Interlibrary Loans / standards; Libraries, Medical / standards; Microscopy, Electron, Scanning / standards; Photography / standards; United States
TL;DR:
This study addressed whether scans of figures in black and white, grayscale, or color, or portable document format to tagged image file format (TIFF) conversions as provided by interlibrary loan or document delivery were viewed as acceptable or useful by radiologists or pathologists.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Recombinase-Dependent Mouse Lines for Chemogenetic Activation of Genetically Defined Cell Types
CELL REPORTS, 15(11), 2563–2573.
MeSH headings : Alleles; Animals; Anxiety / complications; Anxiety / pathology; Anxiety / physiopathology; Behavior, Animal / drug effects; Clozapine; Dendrites / drug effects; Dendrites / metabolism; Designer Drugs / pharmacology; Gamma Rhythm / drug effects; Genetic Techniques; Hippocampus / drug effects; Hippocampus / pathology; Hippocampus / physiopathology; Humans; Hypothermia / complications; Hypothermia / pathology; Hypothermia / physiopathology; Integrases / metabolism; Locomotion / drug effects; Mice; Neuroglia / drug effects; Neuroglia / metabolism; Receptor, Muscarinic M3 / genetics; Recombination, Genetic / genetics
TL;DR:
It is confirmed that activation of hM3Dq is sufficient to dose-dependently evoke phenotypic changes, without extreme phenotypes associated with hM2Dq overexpression, and offer the ability to non-invasively control activity of diverse cell types to uncover their function and dysfunction at any developmental stage.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Evaluation of Clinical Metrology Instrument in Dogs with Osteoarthritis
JOURNAL OF VETERINARY INTERNAL MEDICINE, 30(3), 836–846.
author keywords: Analgesia; Client metrology instrument; Degenerative joint disease; Questionnaire
MeSH headings : Animals; Antibodies / immunology; Antibodies / therapeutic use; Dog Diseases / immunology; Dog Diseases / physiopathology; Dog Diseases / therapy; Dogs; Double-Blind Method; Immunotherapy / veterinary; Nerve Growth Factor / immunology; Osteoarthritis / physiopathology; Osteoarthritis / therapy; Osteoarthritis / veterinary; Pain / drug therapy; Pain / veterinary; Pain Measurement / veterinary; Pilot Projects; Proof of Concept Study
TL;DR:
There is little difference between independent and dependent interviewing, however, dependent interviewing resulted in increased treatment effect sizes and investigators could increase clinical trial power through minimal change to study design.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Detection of Copy Number Imbalance in Canine Urothelial Carcinoma With Droplet Digital Polymerase Chain Reaction
VETERINARY PATHOLOGY, 53(4), 764–772.
author keywords: comparative genomic hybridization; cytogenetics; dogs; molecular diagnostic; transitional cell carcinoma; polymerase chain reaction; urinary bladder; urothelial carcinoma
MeSH headings : Animals; Carcinoma, Transitional Cell / diagnosis; Carcinoma, Transitional Cell / genetics; Carcinoma, Transitional Cell / pathology; Carcinoma, Transitional Cell / veterinary; Comparative Genomic Hybridization / veterinary; DNA Copy Number Variations; Dog Diseases / diagnosis; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Polymerase Chain Reaction / veterinary; Urinary Bladder / pathology; Urinary Bladder Neoplasms / diagnosis; Urinary Bladder Neoplasms / genetics; Urinary Bladder Neoplasms / pathology; Urinary Bladder Neoplasms / veterinary; Urologic Neoplasms / diagnosis; Urologic Neoplasms / genetics; Urologic Neoplasms / pathology; Urologic Neoplasms / veterinary
TL;DR:
The findings show that ddPCR is a useful molecular technique to detect CNAs and may be used as a noninvasive molecular diagnostic test for canine UC.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
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