Works Published in 2019
Displaying works 121 - 140 of 215 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2019 article
Editorial note to the Special Issue "Advances in Bioceramics"
Baino, F., Marchi, J., & Narayan, R. (2019, September). INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY, Vol. 16, pp. 1752–1752.
Source: Web Of Science
Added: August 19, 2019
2019 journal article
G-Quadruplex Structure Improves the Immunostimulatory Effects of CpG Oligonucleotides
NUCLEIC ACID THERAPEUTICS, 29(4), 224–229.
author keywords: CpG ODN; toll-like receptor 9; G-quadruplex; IL-6; peripheral blood mononuclear cells
MeSH headings : Adjuvants, Immunologic / genetics; Adjuvants, Immunologic / pharmacology; Animals; Cell Line; CpG Islands / drug effects; G-Quadruplexes; Humans; Immunologic Factors / genetics; Leukocytes, Mononuclear / drug effects; Leukocytes, Mononuclear / immunology; Nucleic Acid Conformation / drug effects; Oligonucleotides, Antisense / chemistry; Oligonucleotides, Antisense / genetics; Phosphates / chemistry; Phosphates / metabolism
TL;DR:
Results indicate that G-quadruplex formation can be used to increase the immunostimulatory activity of CpG ODNs having a natural PD backbone.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 19, 2019
2019 journal article
On Command Drug Delivery via Cell-Conveyed Phototherapeutics
SMALL, 15(37).
author keywords: drug delivery; photolysis; prodrugs; red blood cells; vitamin B12
MeSH headings : Animals; Bridged-Ring Compounds / chemistry; Drug Carriers / chemistry; Drug Delivery Systems / methods; Erythrocytes / cytology; Female; Flow Cytometry; Humans; Mice; Photolysis; Prodrugs / chemistry; Taxoids / chemistry; Vitamin B 12 / chemistry
TL;DR:
Herein, the use of red blood cells (RBCs) as carriers of cytoplasmically interned phototherapeutic agents is described, and photolysis promotes drug release from the RBC carrier thereby providing the means to target specific diseased sites.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 19, 2019
2019 journal article
Prolonged time course of population excitatory postsynaptic potentials in motoneurons of chronic stroke survivors
JOURNAL OF NEUROPHYSIOLOGY, 122(1), 176–183.
author keywords: double stimulation; EPSP time course; reflex; spasticity; stroke
MeSH headings : Adult; Aged; Excitatory Postsynaptic Potentials; Female; H-Reflex; Humans; Male; Middle Aged; Motor Neurons / physiology; Reaction Time; Stroke / physiopathology
TL;DR:
It is proposed that one potential mechanism for hyperexcitability of spastic motoneurons in chronic stroke survivors may be associated with this prolongation of the Ia EPSP time-course, and the subthreshold double-stimulation approach could provide a noninvasive tool for quantifying the time of EPSPs in both healthy and pathological conditions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 12, 2019
2019 review
Biomimetic Strategies To Treat Traumatic Brain Injury by Leveraging Fibrinogen
[Review of ]. BIOCONJUGATE CHEMISTRY, 30(7), 1951–1956.
MeSH headings : Biomimetics; Blood-Brain Barrier; Brain Injuries, Traumatic / therapy; Fibrinogen / metabolism; Humans
TL;DR:
This work deconstructs what components of fibrinogen may be beneficial as well as, potentially harmful, following TBI and extrapolate this to biomimetic approaches to treat bleeding and trauma that may, also, lead to better outcomesFollowing TBI.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 12, 2019
2019 journal article
Application of Cognitive Task Performance Modeling for Assessing Usability of Transradial Prostheses
IEEE TRANSACTIONS ON HUMAN-MACHINE SYSTEMS, 49(4), 381–387.
Contributors: M. Zahabi*, M. White *, W. Zhang n, A. Winslow n, F. Zhang n , H. Huang n , D. Kaber*
author keywords: Cognitive modeling; GOMSL; mental workload; prosthetics
TL;DR:
Investigating the use of cognitive modeling to assess the usability of an upper-limb prosthesis with a focus on mental workload responses revealed the PR mode to be more intuitive, reduce cognitive load, and increase efficiency in prosthetic control as compared to the DC mode.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 12, 2019
2019 journal article
Hyaluronic Acid Hydrogel Integrated with Mesenchymal Stem Cell-Secretome to Treat Endometrial Injury in a Rat Model of Asherman's Syndrome
ADVANCED HEALTHCARE MATERIALS, 8(14).
author keywords: Asherman's syndrome; endometrial injury; hyaluronic acid; mesenchymal stem cells; secretome
MeSH headings : Animals; Disease Models, Animal; Electrocoagulation; Endometrium / injuries; Female; Gynatresia / therapy; Human Umbilical Vein Endothelial Cells / metabolism; Humans; Hyaluronic Acid / chemistry; Hydrogels / chemistry; Mesenchymal Stem Cells / metabolism; Pregnancy; Rats, Sprague-Dawley
TL;DR:
The HA gel/MSC‐Sec treatment paradigm creates a sustained release system that repairs endometrial injury in rats and promotes viable pregnancy, and holds great potential for the treatment of AS.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: August 12, 2019
2019 journal article
Quadriceps weakness associates with greater T1 rho relaxation time in the medial femoral articular cartilage 6months following anterior cruciate ligament reconstruction
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY, 27(8), 2632–2642.
author keywords: Posttraumatic osteoarthritis; T1rho; Knee extensor; Proteoglycan
MeSH headings : Adolescent; Adult; Anterior Cruciate Ligament Injuries / surgery; Anterior Cruciate Ligament Reconstruction; Cartilage, Articular / chemistry; Cartilage, Articular / diagnostic imaging; Cross-Sectional Studies; Female; Femur / surgery; Humans; Isometric Contraction; Knee Joint / diagnostic imaging; Knee Joint / surgery; Magnetic Resonance Imaging / methods; Male; Meniscus; Muscle Strength; Patellar Ligament / transplantation; Proteoglycans / analysis; Quadriceps Muscle / physiology; Transplantation, Autologous; Young Adult
TL;DR:
The association between weaker quadriceps and greater T1ρ relaxation times in the MFC suggests deficits in lower extremity muscle strength may be related to cartilage composition as early as 6 months following ACLR.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: August 12, 2019
2019 journal article
Lighting Up Biosensors: Now and the Decade To Come
ANALYTICAL CHEMISTRY, 91(14), 8732–8738.
MeSH headings : Animals; Biosensing Techniques / instrumentation; Biosensing Techniques / methods; Equipment Design; Humans; Optical Devices; Optics and Photonics / instrumentation; Optics and Photonics / methods
TL;DR:
The innovative approaches to overcoming existing hurdles to practical biosensor designs are reviewed and potential areas for future breakthroughs in optical biosensor technology are explored.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 5, 2019
2019 review
Physics of bioprinting
[Review of ]. APPLIED PHYSICS REVIEWS, 6(2).
TL;DR:
The physics that underpins the most commonly employed approaches, such as extrusion, laser-based, and inkjet bioprinting are reviewed and an overview of the relevant parameters, their inter-relationships, and the equations that govern the various printing processes are provided.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure
(Web of Science)
Source: Web Of Science
Added: July 29, 2019
2019 journal article
Hemicraniectomy in Traumatic Brain Injury: A Noninvasive Platform to Investigate High Gamma Activity for Brain Machine Interfaces
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING, 27(7), 1467–1472.
author keywords: Brain-machine interface; brain-computer interface; EEG; traumatic brain injury; high gamma
MeSH headings : Adult; Artifacts; Brain Injuries, Traumatic / surgery; Brain-Computer Interfaces; Decompressive Craniectomy / methods; Electroencephalography; Female; Fingers / innervation; Gamma Rhythm; Humans; Magnetoencephalography; Male; Muscle Contraction; Prosthesis Design; Psychomotor Performance
TL;DR:
Results indicate that people with hemicraniectomies can provide a useful resource for developing BMI therapies for the treatment of brain injury, and describe a new BMI paradigm to investigate the use of higher frequency signals in brain-injured subjects without incurring significant risk.
(via Semantic Scholar)
Source: Web Of Science
Added: July 29, 2019
2019 journal article
Intracochlear Electrocochleography: Response Patterns During Cochlear Implantation and Hearing Preservation
EAR AND HEARING, 40(4), 833–848.
author keywords: Cochlear implant; Electrocochleography; Hearing preservation; Intraoperative Monitoring
MeSH headings : Adolescent; Adult; Aged; Audiometry, Evoked Response / methods; Child; Child, Preschool; Cochlea / physiopathology; Cochlea / surgery; Cochlear Implantation / methods; Cochlear Implants; Female; Hearing; Hearing Loss, Sensorineural / physiopathology; Hearing Loss, Sensorineural / rehabilitation; Humans; Infant; Male; Middle Aged; Monitoring, Intraoperative / methods; Round Window, Ear; Speech Perception; Young Adult
TL;DR:
The correlation between the absolute magnitude obtained either before or during insertion of the ECochG and the hearing threshold changes suggest that cochlear health, which varies by subject, plays an important role.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: July 29, 2019
2019 journal article
Proportional Myoelectric Control of a Virtual Inverted Pendulum Using Residual Antagonistic Muscles: Toward Voluntary Postural Control
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING, 27(7), 1473–1482.
Contributors: A. Fleming n, S. Huang n & H. Huang n
author keywords: Electromyography; myoelectric control; postural control; volitional control; transtibial amputees; lower-limb amputees; residual muscles
MeSH headings : Adaptation, Psychological; Adult; Aged; Algorithms; Amputees; Ankle / physiology; Biomechanical Phenomena; Electromyography / methods; Female; Healthy Volunteers; Humans; Male; Middle Aged; Muscle Contraction / physiology; Muscle, Skeletal / physiology; Postural Balance; Posture / physiology; Psychomotor Performance; Virtual Reality
TL;DR:
The results suggest that after the training of transtibial amputees in coordinating antagonistic residual muscles in dynamic systems, it may be feasible to implement the proportional myoelectric control of the powered ankle prostheses in order to assist the postural control mechanisms, such as anticipatory and compensatory postural adjustments.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: July 29, 2019
2019 journal article
Photothermal Therapy Promotes Tumor Infiltration and Antitumor Activity of CAR T Cells
ADVANCED MATERIALS, 31(23).
author keywords: CAR T cells; cell therapy; drug delivery; immunotherapy; photothermal therapy
MeSH headings : Animals; Antigens / metabolism; Cell Line, Tumor; Chondroitin Sulfate Proteoglycans / metabolism; Combined Modality Therapy; Female; Heterografts; Humans; Hyperthermia, Induced; Immunotherapy, Adoptive / methods; Indocyanine Green / chemistry; Melanoma / pathology; Melanoma / therapy; Membrane Proteins / metabolism; Mice, SCID; Nanoparticles / chemistry; Photosensitizing Agents / chemistry; Phototherapy / methods; Polylactic Acid-Polyglycolic Acid Copolymer / chemistry; Proteoglycans / metabolism; Skin Neoplasms / pathology; Skin Neoplasms / therapy; T-Lymphocytes / metabolism; T-Lymphocytes / transplantation; Tumor Microenvironment
TL;DR:
It is found that the chondroitin sulfate proteoglycan‐4 (CSPG4)‐specific CAR T cells infused in Nod scid gamma mice engrafted with the human melanoma WM115 cell line have superior antitumor activity after photothermal ablation of the tumor.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: July 22, 2019
2019 journal article
Time-dependent tuning of balance control and aftereffects following optical flow perturbation training in older adults
JOURNAL OF NEUROENGINEERING AND REHABILITATION, 16.
MeSH headings : Aged; Biomechanical Phenomena; Female; Humans; Male; Muscle, Skeletal / physiology; Physical Therapy Modalities; Postural Balance / physiology; Sensation Disorders / rehabilitation; Walking / physiology
TL;DR:
Investigation of the propensity for time-dependent tuning of walking balance control and the presence of aftereffects following a single session of optical flow perturbation training suggests that older adults respond to the onset of perturbations using generalized anticipatory balance control, deprioritize that strategy following prolonged exposure to perturbATIONS, and exhibit short-term aftereeffects that indicate a lessening of anticipatory control, an increase in reactive control, and/or increased balance confidence.
(via Semantic Scholar)
jneuroengrehab.biomedcentral.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: July 22, 2019
2019 journal article
Extraction of Plant DNA by Microneedle Patch for Rapid Detection of Plant Diseases
ACS NANO, 13(6), 6540–6549.
author keywords: plant disease; DNA extraction; microneedle patch; Phytophthora infestans; nucleic acid amplification; point-of-care diagnostics
MeSH headings : DNA Barcoding, Taxonomic / instrumentation; DNA Barcoding, Taxonomic / methods; DNA, Fungal / chemistry; DNA, Fungal / genetics; Solanum lycopersicum / microbiology; Metagenomics / instrumentation; Metagenomics / methods; Needles; Phytophthora / genetics; Phytophthora / pathogenicity; Plant Diseases / microbiology; Plant Leaves / chemistry; Plant Leaves / microbiology
TL;DR:
A simple, cell-lysis-free, and purification-free DNA extraction method that could be a transformative approach to facilitate rapid sample preparation for molecular diagnosis of various plant diseases directly in the field is developed.
(via Semantic Scholar)
Source: Web Of Science
Added: July 15, 2019
2019 journal article
Mechanical Characterization of 3D Ovarian Cancer Nodules Using Brillouin Confocal Microscopy
CELLULAR AND MOLECULAR BIOENGINEERING, 12(3), 215–226.
author keywords: Tumors; Osmolality; Young's modulus; Stiffness; Spheroids; Optics; Atomic force microscopy; MicroSquisher
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: July 15, 2019
2019 journal article
Interferon-lambda 3 Promotes Epithelial Defense and Barrier Function Against Cryptosporidium parvum Infection
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 8(1), 1–20.
author keywords: Cryptosporidiosis; Cytokine; Enterocyte; Protozoa
MeSH headings : Animals; Cell Line; Cryptosporidiosis / genetics; Cryptosporidiosis / immunology; Cryptosporidiosis / parasitology; Cryptosporidium parvum / physiology; Cytokines / genetics; Cytokines / metabolism; Disease Models, Animal; Gene Expression Profiling; Intestinal Mucosa / immunology; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Swine; Up-Regulation
TL;DR:
These studies identify IFN-λ2/3 as a key epithelial defense mechanism against C parvum infection and Priming of IECs with recombinant human IFn-λ3 promoted cellular defense against CParvum infections and abrogated C parVum–induced loss of barrier function by decreasing paracellular permeability to sodium.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: July 15, 2019
2019 journal article
Independent component analysis based algorithms for high-density electromyogram decomposition: Systematic evaluation through simulation
COMPUTERS IN BIOLOGY AND MEDICINE, 109, 171–181.
author keywords: Biosignal processing; Electromyogram; Source separation; Independent component analysis; RobustICA; Simulation
MeSH headings : Algorithms; Electromyography; Humans; Muscle Contraction / physiology; Muscle, Skeletal / physiology; Pattern Recognition, Automated; Signal Processing, Computer-Assisted
TL;DR:
The RobustICA consistently showed high decomposition accuracy among the three algorithms under a variety of signal conditions, especially with a low signal quality and varying contraction levels, which provides guidance on selecting particular decomposition algorithms based on specific applications with different requirement on the accuracy/yield of the decomposition.
(via Semantic Scholar)
Source: Web Of Science
Added: July 8, 2019
2019 journal article
Ankle power biofeedback attenuates the distal-to-proximal redistribution in older adults
GAIT & POSTURE, 71, 44–49.
author keywords: Plantarflexor; Push-off; Gait; Elderly; Hip
MeSH headings : Aged; Ankle Joint / physiology; Biofeedback, Psychology; Biomechanical Phenomena; Female; Gait / physiology; Humans; Kinetics; Male; Walking / physiology; Walking Speed; Young Adult
TL;DR:
Older adults are capable of increasing ankle power through targeted ankle power biofeedback - effects that are accompanied by diminished hip power output and attenuation of the distal-to-proximal redistribution.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: July 8, 2019
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