Works Published in 2021

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Displaying works 141 - 160 of 246 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2021 journal article

Synthesis of sonicated fibrin nanoparticles that modulate fibrin clot polymerization and enhance angiogenic responses

COLLOIDS AND SURFACES B-BIOINTERFACES, 204.

author keywords: Fibrin; Nanoparticles; Wound healing; Regenerative medicine; Fibrin sealant
MeSH headings : Fibrin; Fibrin Tissue Adhesive; Nanoparticles; Polymerization; Wound Healing
TL;DR: It is shown that SFBNs may be a promising wound healing therapy that can be easily produced and delivered in a flowable formulation and support cell migration in an in vitro angiogenic sprouting assay, relevant for wound healing. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: July 19, 2021

2021 journal article

ON THE RELATIONSHIP BETWEEN SPATIAL COHERENCE AND IN SITU PRESSURE FOR ABDOMINAL IMAGING

ULTRASOUND IN MEDICINE AND BIOLOGY, 47(8), 2310–2320.

By: B. Zhang*, G. Pinton n & K. Nightingale*

author keywords: Mechanical index; In situ pressure; Spatial coherence; Tissue harmonic imaging; Measurement techniques; Abdominal ultrasound; Simulation
MeSH headings : Abdomen / diagnostic imaging; Animals; Phantoms, Imaging; Pressure; Swine; Ultrasonography
TL;DR: Strong correlation between both spatial coherence-based metrics and in situ PRP is demonstrated, an observation that could be leveraged in the future for patient-specific selection of acoustic output. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: July 19, 2021

2021 review

Mitochondria-targeted graphene for advanced cancer therapeutics

[Review of ]. ACTA BIOMATERIALIA, 129, 43–56.

author keywords: Mitochondria; Mitochondria-targeted graphene; Cancer; Therapy
MeSH headings : Animals; Antineoplastic Agents / pharmacology; Antineoplastic Agents / therapeutic use; Graphite; Mitochondria; Nanoparticles; Neoplasms / drug therapy
TL;DR: This review considers the cross-disciplinary nature of this area and focuses on the design and development of mitochondria-targeted graphene (mitoGRAPH), its immense potential, and future use for selective targeting of cancer mitochondria. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: July 19, 2021

2021 journal article

Static and dynamic proprioceptive recognition through vibrotactile stimulation

JOURNAL OF NEURAL ENGINEERING, 18(4).

By: L. Vargas n, H. Huang n, Y. Zhu n & X. Hu n

Contributors: L. Vargas n, H. Huang n, Y. Zhu n & X. Hu n

author keywords: somatosensory feedback; proprioception; vibrotactile stimulation; arm function; sensory substitution
MeSH headings : Feedback, Sensory; Forearm; Goals; Humans; Movement; Proprioception
TL;DR: The outcomes suggest that information pertaining to static and dynamic aspects of proprioception can be accurately delivered using an array of vibrotactors and could be used to potentially evaluate the sensorimotor integration processes during human–machine interactions, and to improve sensory feedback in clinical populations with somatosensory impairments. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: July 19, 2021

2021 article

Editorial: Tendon Structure-Function Relationship in Health, Ageing, and Injury

Maas, H., Arndt, T., & Franz, J. R. (2021, June 18). FRONTIERS IN SPORTS AND ACTIVE LIVING, Vol. 3.

By: H. Maas*, T. Arndt* & J. Franz n

author keywords: subtendon; non-uniform deformation; Achilles tendon; ultrasound; aging; skeletal muscle
Source: Web Of Science
Added: July 19, 2021

2021 review

Biosensing applications of carbon-based materials

[Review of ]. CURRENT OPINION IN BIOMEDICAL ENGINEERING, 18.

author keywords: Biosensing; graphene oxide; Carbon nanotubes; Graphite; Glassy carbon electrode; Graphene quantum dots; COVID-19
TL;DR: A brief account provides a description of recent efforts involving the use of carbon-based materials for biosensing and related biomedical applications. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: July 12, 2021

2021 journal article

Characterization of an Array-Based Dual-Frequency Transducer for Superharmonic Contrast Imaging

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 68(7), 2419–2431.

author keywords: Imaging; Transducers; Probes; Harmonic analysis; Acoustics; Acoustic arrays; Ultrasonic imaging; Acoustic angiography; array transducer; dual-frequency (DF); microbubble (MB) contrast agents; superharmonic imaging
MeSH headings : Angiography; Animals; Contrast Media; Mice; Microbubbles; Phantoms, Imaging; Transducers; Ultrasonography
TL;DR: In vitro contrast channel phantom imaging and in vivo xenograft mouse tumor imaging by this probe with superharmonic imaging showed contrast-to-tissue ratio improvements, compared to line-by-line micro-ultrasound B-mode imaging. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: July 12, 2021

2021 review

Neonatal coagulopathies: A review of established and emerging treatments

[Review of ]. EXPERIMENTAL BIOLOGY AND MEDICINE, 246(12), 1447–1457.

author keywords: Neonatal; coagulopathy; developmental hemostasis; transfusion
MeSH headings : Animals; Blood Coagulation Disorders / etiology; Blood Coagulation Disorders / therapy; Hemorrhage / etiology; Hemorrhage / therapy; Hemostasis / physiology; Humans; Infant, Newborn; Infant, Newborn, Diseases / etiology; Infant, Newborn, Diseases / therapy
TL;DR: This mini-review examines the current understanding of neonatal hemostatic balance and treatment of Neonatal coagulopathies, with particular emphasis on emerging treatment methods and areas in need of further investigative efforts. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: July 12, 2021

2021 article

Ex vivo evaluation of novel core tenorrhaphy patterns in dogs

Chiu, K. W., Duffy, D. J., Chang, Y.-J., Gaffney, L., & Fisher, M. B. (2021, July 6). VETERINARY SURGERY.

By: K. Chiu n, D. Duffy n, Y. Chang n, L. Gaffney n & M. Fisher n

MeSH headings : Animals; Biomechanical Phenomena; Cadaver; Dog Diseases; Dogs; Random Allocation; Suture Techniques / veterinary; Sutures / veterinary; Tendon Injuries / surgery; Tendon Injuries / veterinary; Tensile Strength
TL;DR: Use of novel patterns ExDCrL, EmDCrl, and MTang improved resistance to loads and gap formation and were biomechanically superior compared to 3LP in healthy canine tendon repairs in dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: July 12, 2021

2021 article

Cueing Changes in Peak Vertical Ground Reaction Force to Improve Coordination Dynamics in Walking

Armitano-Lago, C., Pietrosimone, B., Evans-Pickett, A., Davis-Wilson, H., Franz, J. R., Blackburn, T., & Kiefer, A. W. (2021, May 15). JOURNAL OF MOTOR BEHAVIOR.

By: C. Armitano-Lago*, B. Pietrosimone*, A. Evans-Pickett*, H. Davis-Wilson*, J. Franz n, T. Blackburn*, A. Kiefer*

author keywords: biofeedback; anterior cruciate ligament reconstruction; cross recurrence; relative phase
MeSH headings : Anterior Cruciate Ligament Injuries / surgery; Anterior Cruciate Ligament Reconstruction; Biomechanical Phenomena; Gait; Humans; Knee Joint; Walking
TL;DR: With thoughtful consideration for movement control, biofeedback can be used to target mechanisms leading to long-term deleterious joint adaptations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: July 6, 2021

2021 article

Phase separation drives aberrant chromatin looping and cancer development

Ahn, J. H., Davis, E. S., Daugird, T. A., Zhao, S., Quiroga, I. Y., Uryu, H., … Wang, G. G. (2021, June 23). NATURE.

MeSH headings : Animals; Carcinogenesis; Chromatin / genetics; Female; HEK293 Cells; HeLa Cells; Homeodomain Proteins / genetics; Humans; Intrinsically Disordered Proteins / genetics; Mice; Mice, Inbred BALB C; Neoplasms / genetics; Neoplasms / pathology; Nuclear Pore Complex Proteins / genetics; Oncogene Proteins, Fusion / genetics; Transcription Factors / genetics; Transcriptional Activation; Translocation, Genetic
TL;DR: A proof-of-principle example in which cancer acquires mutation to establish oncogenic transcription factor condensates via phase separation, which simultaneously enhances their genomic targeting and induces organization of aberrant three-dimensional chromatin structure during tumourous transformation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: July 6, 2021

2021 journal article

Artificial complementary chromatic acclimation gene expression system in Escherichia coli

MICROBIAL CELL FACTORIES, 20(1).

By: D. Ariyanti*, K. Ikebukuro* & K. Sode n

author keywords: Artificial complementary chromatic acclimation; Gene expression system; CcaS; CcaR; Escherichia coli
MeSH headings : Escherichia coli / genetics; Escherichia coli / metabolism; Gene Expression; Gene Expression Regulation, Bacterial; Genes, Reporter; Light; Luminescent Proteins / genetics; Phycobilins / biosynthesis; Phycobilins / genetics; Phycocyanin / biosynthesis; Phycocyanin / genetics; Promoter Regions, Genetic; Synechocystis / genetics; Synechocystis / metabolism; Transcription, Genetic; Transformation, Bacterial
TL;DR: An artificial CCA system was developed to realize a multiple gene expression system, which was regulated by two colors, red and green lights, using a single photosensor system, the CcaS/CcaR system derived from Synechocystis sp. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: July 6, 2021

2021 article

The evaluation of a multiphasic 3D-bioplotted scaffold seeded with adipose derived stem cells to repair osteochondral defects in a porcine model

Nordberg, R. C., Huebner, P., Schuchard, K. G., Mellor, L. F., Shirwaiker, R. A., Loboa, E. G., & Spang, J. T. (2021, June 10). JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS.

By: R. Nordberg n, P. Huebner n, K. Schuchard n, L. Mellor n, R. Shirwaiker n, E. Loboa*, J. Spang*

author keywords: in vivo; osteochondral; stem cells; tissue engineering; 3D-printing
MeSH headings : Animals; Cartilage, Articular / injuries; Stem Cells; Swine; Swine, Miniature; Tissue Engineering / methods; Tissue Scaffolds / chemistry
TL;DR: Overall, scaffold groups repaired the defect more successfully than an open lesion but achieved limited repair in the cartilage region, indicating that this approach holds potential to treat focal cartilage lesions in a highly personalized manner using a human patient's own ASC cells. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: June 21, 2021

2021 journal article

Artificial Olfaction in the 21<sup>st</sup> Century

IEEE Sensors Journal, 21(11), 12969–12990.

author keywords: Artificial olfaction; electronic nose; machine olfaction; odor detection; machine learning; headspace sampling; VOC analysis
TL;DR: The current state of the art that has been achieved over the last two decades as the field of artificial olfaction transitioned into the <inline-formula> <tex-math notation="LaTeX"> Century that served as the foundation upon which the authors have been building their odor-monitoring instrumental and measurement systems. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: June 21, 2021

2021 article

Platelet-like particles reduce coagulopathy-related and neuroinflammatory pathologies post-experimental traumatic brain injury

Todd, J., Bharadwaj, V. N., Nellenbach, K., Nandi, S., Mihalko, E., Copeland, C., … Stabenfeldt, S. E. (2021, June 11). JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS.

author keywords: blood-brain barrier; coagulopathy; neuroinflammation; permeability; platelet-like particles; traumatic brain injury
MeSH headings : Animals; Blood Platelets / metabolism; Blood-Brain Barrier / metabolism; Brain Injuries, Traumatic / complications; Brain Injuries, Traumatic / drug therapy; Brain Injuries, Traumatic / metabolism; Disease Models, Animal; Mice; Microglia / metabolism
TL;DR: Results suggest that PLP-treatment addressed acute hypocoagulation and decreased BBB permeability followed by decreased neuroinflammation and fold-change tissue loss by 7 days post-injury, indicating that PLPs could be a potential therapeutic modality for TBI. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: June 21, 2021

2021 journal article

Effect of Photoinitiator on Precursory Stability and Curing Depth of Thiol-Ene Clickable Gelatin

POLYMERS, 13(11).

author keywords: photoinitiator; hydrogel; polymerization; visible light; gelatin; thiol-ene click chemistry
TL;DR: The use of the visible light based Ru/SPS photo-initiator for constructs requiring rapid gelation and a good curing depth while Ig2959 or LAP can be applied for photo-polymerization of GelAGE materials requiring long-term incubation prior to application if UV is not a concern. (via Semantic Scholar)
Source: Web Of Science
Added: June 21, 2021

2021 journal article

Influence of Brachial Plexus Birth Injury Location on Glenohumeral Joint Morphology

JOURNAL OF HAND SURGERY-AMERICAN VOLUME, 46(6).

By: N. Dixit n, C. McCormick n, J. Cole n & K. Saul n

author keywords: Brachial plexus birth injury; glenoid inclination; glenoid version; humeral head morphology; radius of curvature
MeSH headings : Animals; Birth Injuries / diagnostic imaging; Brachial Plexus / diagnostic imaging; Brachial Plexus / injuries; Brachial Plexus Neuropathies / diagnostic imaging; Brachial Plexus Neuropathies / etiology; Humans; Rats; Rats, Sprague-Dawley; Shoulder Joint / diagnostic imaging; X-Ray Microtomography
TL;DR: It is suggested that glenoid deformities occur after postganglionics BPBI but not after preganglionic BPBI, whereas the humeral head is smaller after pre ganglionic injury, possibly suggesting an overall decreased biological growth rate in this group. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: June 21, 2021

2021 review

Recent advances in carbon nanomaterials for biomedical applications: A review

[Review of ]. CURRENT OPINION IN BIOMEDICAL ENGINEERING, 17.

By: P. Riley n & R. Narayan n

author keywords: Graphene; Carbon nanotubes; Drug delivery; Cancer therapy; Antiviral activity
TL;DR: A review on the latest progress involving the use of carbon nanostructures, namely fullerenes, graphene, and carbon nanotubes, for drug delivery, cancer therapy, and antiviral applications is provided. (via Semantic Scholar)
Source: Web Of Science
Added: June 21, 2021

2021 journal article

Electrochemical quantification of accelerated FADGDH rates in aqueous nanodroplets

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 118(25).

author keywords: nanoelectrochemistry; nanodroplet; enzymology; FADGDH; reaction acceleration
MeSH headings : Electrochemistry; Electrodes; Flavin-Adenine Dinucleotide; Glucose Dehydrogenases / metabolism; Nanoparticles / chemistry; Water / chemistry
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 16, 2021

2021 journal article

Integrated microneedle-smartphone nucleic acid amplification platform for in-field diagnosis of plant diseases

BIOSENSORS & BIOELECTRONICS, 187.

author keywords: Plant disease diagnostics; Nucleic acid extraction; Microneedle; Isothermal amplification; Smartphone
MeSH headings : Biosensing Techniques; Molecular Diagnostic Techniques; Nucleic Acid Amplification Techniques; Plant Diseases; Smartphone
TL;DR: It is found that the MN patch containing as few as a single needle tip successfully extracted enough RNA for RT-PCR or RT-LAMP analysis, and MN-extracted RNA samples remained stable on MN surfaces for up to three days. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: June 14, 2021

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