Works Published in 2016
Displaying works 101 - 120 of 173 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2016 journal article
An Integrated System for Superharmonic Contrast-Enhanced Ultrasound Imaging: Design and Intravascular Phantom Imaging Study
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 63(9), 1933–1943.
author keywords: Acoustic angiography; biomedical electronics; field-programmable gate arrays (FPGA); intravascular ultrasound (IVUS); microbubble contrast agent (MCA); ultrasonic imaging; ultrasonic transducer
MeSH headings : Arteries / diagnostic imaging; Contrast Media; Elasticity Imaging Techniques / instrumentation; Elasticity Imaging Techniques / methods; Equipment Design; Equipment Failure Analysis; Humans; Image Enhancement / instrumentation; Image Enhancement / methods; Phantoms, Imaging; Reproducibility of Results; Sensitivity and Specificity; Signal Processing, Computer-Assisted / instrumentation; Systems Integration; Ultrasonography, Interventional / instrumentation; Ultrasonography, Interventional / methods
TL;DR:
The system greatly reduced the cost and complexity of the superharmonic imaging intended for preclinical study and showed promise for high-contrast intravascular microvascular imaging, which may have significant importance in assessment of the vasa vasorum associated with atherosclerotic plaques.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 article
Acoustic angiography: A new high frequency contrast ultrasound technique for biomedical imaging
SENSING AND ANALYSIS TECHNOLOGIES FOR BIOMEDICAL AND COGNITIVE APPLICATIONS 2016, Vol. 9871.
author keywords: Ultrasound; contrast agent; microbubble; microvasculature; angiogenesis; broadband; superharmonic; transducer; dual-frequency; acoustic angiography
TL;DR:
Data shows that acoustic angiography can provide important information about the presence of disease based on vascular patterns, and may enable a new paradigm in medical imaging.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 article
A piezoelectric shear stress sensor
SENSORS AND SMART STRUCTURES TECHNOLOGIES FOR CIVIL, MECHANICAL, AND AEROSPACE SYSTEMS 2016, Vol. 9803.
author keywords: PMN-33% PT crystal; bimorph piezoelectric structures; floating element; electromechanical symmetry
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Wideband acoustic activation and detection of droplet vaporization events using a capacitive micromachined ultrasonic transducer
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA, 139(6), 3193–3198.
MeSH headings : Contrast Media / chemistry; Equipment Design; Fluorocarbons / chemistry; Lipids / chemistry; Microbubbles; Time Factors; Transducers; Ultrasonography / instrumentation; Volatilization
TL;DR:
This study exploited the wide bandwidth of a 128-element capacitive micromachined ultrasonic transducer array for activation and real-time imaging of ADV events from droplets circulating in a tube to provide a substantial increase of the contrast-to-noise ratio.
(via Semantic Scholar)
europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Whole-Body and Local Muscle Vibration Immediately Improve Quadriceps Function in Individuals With Anterior Cruciate Ligament Reconstruction
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION, 97(7), 1121–1129.
author keywords: Knee; Muscles; Osteoarthritis; Rehabilitation; Resistance training
MeSH headings : Anterior Cruciate Ligament Reconstruction / rehabilitation; Cross-Over Studies; Evoked Potentials, Motor; Female; Humans; Isometric Contraction / physiology; Knee Joint / physiopathology; Male; Muscle Strength / physiology; Physical Therapy Modalities; Quadriceps Muscle / physiopathology; Single-Blind Method; Torque; Vibration / therapeutic use; Young Adult
TL;DR:
WBV and LMV acutely improved quadriceps function and could be useful modalities for restoring quadricePS strength in individuals with knee pathologies.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Towards an Integrated Microneedle Total Analysis Chip for Protein Detection
ELECTROANALYSIS, 28(6), 1305–1310.
author keywords: lab-on-chip; biosensor; immunoassay; microneedle; myoglobin; troponin
TL;DR:
The results presented here provide an important proof-of-concept demonstration of integration of microneedles with a microchip platform containing fluidic channels and electrode transducers that may be used to extract interstitial fluid and monitor biologically important molecules.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Single Cell Chemical Cytometry of Akt Activity in Rheumatoid Arthritis and Normal Fibroblast-like Synoviocytes in Response to Tumor Necrosis Factor alpha
ANALYTICAL CHEMISTRY, 88(15), 7786–7792.
MeSH headings : Arthritis, Rheumatoid / metabolism; Arthritis, Rheumatoid / pathology; Cells, Cultured; Chromones / pharmacology; Electrophoresis, Capillary; Fibroblasts / cytology; Humans; Insulin / pharmacology; Morpholines / pharmacology; Phosphorylation; Proto-Oncogene Proteins c-akt / antagonists & inhibitors; Proto-Oncogene Proteins c-akt / genetics; Proto-Oncogene Proteins c-akt / metabolism; RNA Interference; RNA, Small Interfering / metabolism; Receptors, Tumor Necrosis Factor, Type I / metabolism; Signal Transduction / drug effects; Single-Cell Analysis; Synoviocytes / cytology; Synoviocytes / drug effects; Synoviocytes / metabolism; Tumor Necrosis Factor-alpha / pharmacology
TL;DR:
It is expected that chemical cytometry studies pairing peptide reporters with capillary electrophoresis will provide valuable data regarding aberrant kinase activity from small samples of clinical interest, suggesting heterogeneity in Akt and protease activity that may play a role in the RA-affected joint.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Enhanced Antiglioblastoma Efficacy of Neovasculature and Glioma Cells Dual Targeted Nanoparticles
MOLECULAR PHARMACEUTICS, 13(10), 3506–3517.
author keywords: glioma; antineovasculature; dual-targeted nanoparticle; drug delivery; paclitaxel
MeSH headings : Animals; Antineoplastic Agents, Phytogenic / chemistry; Antineoplastic Agents, Phytogenic / therapeutic use; Cell Line, Tumor; Drug Delivery Systems; Glioblastoma / drug therapy; Glioma / drug therapy; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles / chemistry; Paclitaxel / chemistry; Paclitaxel / therapeutic use; Polyesters / chemistry; Polyethylene Glycols / chemistry; Rats
TL;DR:
The in vivo antiglioma efficacy and safety evaluation showed PC-NP-PTX significantly enhanced the antIGlioma effectiveness and displayed negligible acute toxicity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Creating tissues from textiles: scalable nonwoven manufacturing techniques for fabrication of tissue engineering scaffolds
BIOMEDICAL MATERIALS, 11(1).
author keywords: human adipose derived stem cells; nonwoven tissue engineering scaffolds; scalable tissue engineering
MeSH headings : Adipogenesis / physiology; Biocompatible Materials / chemical synthesis; Cell Differentiation / physiology; Cell Survival / physiology; Cells, Cultured; Equipment Design; Equipment Failure Analysis; Humans; Lactic Acid / chemistry; Materials Testing; Osteogenesis / physiology; Polyesters; Polymers / chemistry; Stem Cells / cytology; Stem Cells / physiology; Textiles; Tissue Engineering / instrumentation; Tissue Engineering / methods; Tissue Scaffolds
TL;DR:
Nonwovens manufactured via these industry standard, commercially relevant manufacturing techniques were capable of supporting hASC attachment, proliferation, and both adipogenic and osteogenic differentiation of hASC, making them promising candidates for commercialization and translation of nonwoven scaffold based tissue engineering strategies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
9. Industry, Innovation and Infrastructure
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Tumor microenvironment and intracellular signal-activated nanomaterials for anticancer drug delivery
MATERIALS TODAY, 19(5), 274–283.
TL;DR:
The focus is placed on design strategies and methods of formulating novel nanoscaled materials for anticancer drug delivery using tumor and endocytic acidities, hypoxia, enzyme overexpression, and high levels of intracellular glutathione, reactive oxygen species, and adenosine-5′-triphosphate.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Transformable DNA nanocarriers for plasma membrane targeted delivery of cytokine
BIOMATERIALS, 96, 1–10.
author keywords: Cancer; Protein delivery; DNA structures; Cytokine; Nanomedicine
TL;DR:
A tumor microenvironment-responsive and transformable nanocarrier for cell membrane targeted delivery of cytokine using a phospholipase A2 degradable liposome as a shell and complementary DNA nanostructures decorated with cytokines as the cores is reported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Improving the analytical performance and versatility of paper spray mass spectrometry via paper microfluidics
ANALYST, 141(13), 4065–4073.
TL;DR:
Two paper-based microfluidic techniques, photolithography and wax patterning, were investigated for their potential to improve upon the sensitivity, reproducibility, and versatility of paper spray mass spectrometry.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Imaging and simulation of Achilles tendon dynamics: Implications for walking performance in the elderly
JOURNAL OF BIOMECHANICS, 49(9), 1403–1410.
author keywords: Ultrasound; Plantarflexor; Aging; Musculoskeletal modeling; Simulation; Biomechanics
MeSH headings : Achilles Tendon / diagnostic imaging; Achilles Tendon / physiology; Aging / physiology; Biomechanical Phenomena; Humans; Models, Biological; Molecular Imaging / methods; Walking / physiology
TL;DR:
Experimental evidence reveals that older tendons exhibit smaller differences in tissue deformations than young adults between regions of the AT presumed to arise from the gastrocnemius and soleus muscles, which could have implications for the mechanical independence of the triceps surae muscles.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 article
Fibrin Network Changes in Neonates after Cardiopulmonary Bypass
Brown, A. C., Hannan, R. H., Timmins, L. H., Fernandez, J. D., Barker, T. H., & Guzzetta, N. A. (2016, May). ANESTHESIOLOGY, Vol. 124, pp. 1021–1031.
MeSH headings : Adult; Blood Coagulation; Blood Loss, Surgical; Blood Transfusion; Cardiopulmonary Bypass / adverse effects; Factor XIII / analysis; Female; Fibrin; Fibrinogen / metabolism; Humans; Infant; Infant, Newborn; Male; Microscopy, Confocal; Prothrombin / analysis
TL;DR:
It is confirmed that significant differences exist in clot structure between neonates and adults and that neonatal and adult fibrinogen may not integrate well and suggested that differential treatment strategies for neonates should be pursued to reduce the demonstrated morbidity of blood product transfusion.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Fabrication of novel high surface area mushroom gilled fibers and their effects on human adipose derived stem cells under pulsatile fluid flow for tissue engineering. applications
ACTA BIOMATERIALIA, 36, 220–230.
author keywords: Gilled high surface area fibers; Human adipose derived stem cells; Pulsatile fluid slow; Shear stress; Scalable tissue engineering scaffolds
MeSH headings : Adipose Tissue / cytology; Adipose Tissue / metabolism; Agaricales; Cells, Cultured; Humans; Pulsatile Flow; Stem Cells / cytology; Stem Cells / metabolism; Tissue Engineering / instrumentation; Tissue Engineering / methods; Tissue Scaffolds / chemistry
TL;DR:
The successful fabrication of novel high surface area gilled fiber scaffolds for tissue engineering applications is reported for the first time, and in the absence of osteogenic induction factors, gilled fibers led to significantly increased mRNA expression of an early marker for osteogenesis after exposure to pulsatile fluid flow.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Evaluation of silver-titanium implants activated by low intensity direct current for orthopedic infection control: An in vitro and in vivo study
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 104(5), 1023–1031.
author keywords: prosthetic infection; oligodynamic silver; antimicrobial implant; electrical activation
MeSH headings : Animals; Female; Femur / microbiology; Femur / surgery; Implants, Experimental; Rats; Rats, Sprague-Dawley; Silver / chemistry; Silver / pharmacology; Staphylococcal Infections / prevention & control; Staphylococcus aureus / growth & development; Titanium / chemistry; Titanium / pharmacology
TL;DR:
In vivo, none of the four groups were able to prevent wound infection, but the experimental group resulted in reduced colonization, and the antimicrobial potential of LIDC-activated Ag-Ti implants is demonstrated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Design and characterization of a microfabricated hydrogen clearance blood flow sensor
JOURNAL OF NEUROSCIENCE METHODS, 267, 132–140.
author keywords: COMSOL Multiphysics; Electrolysis; Gas clearance; Photolithography; Platinum electrode
MeSH headings : Blood Chemical Analysis / instrumentation; Cerebrovascular Circulation / physiology; Computer Simulation; Electrodes, Implanted; Equipment Design; Finite Element Analysis; Hydrogen / analysis; Microtechnology; Norepinephrine / metabolism; Oxygen / analysis; Platinum; Reproducibility of Results
TL;DR:
Microfabrication allows for the high-throughput production of reproducible devices that are capable of monitoring deep brain CBF with sub-minute resolution, and can resolve physiological changes occurring on a shorter timescale than existing gas clearance measurements.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
Alternate Metabolic Programs Define Regional Variation of Relevant Biological Features in Renal Cell Carcinoma Progression
CLINICAL CANCER RESEARCH, 22(12), 2950–2959.
MeSH headings : Biomarkers, Tumor / genetics; Biomarkers, Tumor / metabolism; Carcinoma, Renal Cell / diagnostic imaging; Carcinoma, Renal Cell / genetics; Carcinoma, Renal Cell / pathology; Disease Progression; Gene Expression Regulation, Neoplastic; Humans; Kidney Neoplasms / diagnostic imaging; Kidney Neoplasms / genetics; Kidney Neoplasms / pathology; Magnetic Resonance Imaging / methods; Microarray Analysis; Positron Emission Tomography Computed Tomography / methods
TL;DR:
Higher tumor dependency on exogenous glucose accompanies the development of features associated with the poor risk ccB subgroup, and linking these panels of features may provide the opportunity to create functional maps to enable enhanced visualization of the heterogeneous biologic processes of an individual's disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
ATP-Responsive and Near-Infrared-Emissive Nanocarriers for Anticancer Drug Delivery and Real-Time Imaging
THERANOSTICS, 6(7), 1053–1064.
author keywords: drug delivery; nanomedicine; stimuli-responsive; ATP-responsive; theranostics; conjugated polymers
MeSH headings : Adenosine Triphosphate / metabolism; Antineoplastic Agents / administration & dosage; Boronic Acids / metabolism; Doxorubicin / administration & dosage; Drug Carriers / administration & dosage; Hep G2 Cells; Humans; Liver Neoplasms / diagnostic imaging; Liver Neoplasms / drug therapy; Nanoparticles / administration & dosage; Optical Imaging / methods; Theranostic Nanomedicine / methods
TL;DR:
In vivo studies validate that this adenosine-5'-triphosphate (ATP)-responsive and near-infrared (NIR)-emissive conjugated polymer-based nanocarrier for the controlled release of anticancer drugs and real-time imaging exhibits promising capability for inhibition of tumor growth.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
A genome-wide study of lipid response to fenofibrate in Caucasians: A combined analysis of the GOLDN and ACCORD studies
Pharmacogenetics and Genomics, 26(7), 324–333.
Source: NC State University Libraries
Added: August 6, 2018
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