Works Published in 2020
Displaying works 161 - 180 of 216 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2020 journal article
Automated platform for cell selection and separation based on four-dimensional motility and matrix degradation
ANALYST, 145(7), 2731–2742.
MeSH headings : Automation; Cell Line, Tumor; Cell Movement; Cell Separation / methods; Collagen / chemistry; Humans; Image Processing, Computer-Assisted; Microscopy, Confocal; Tissue Array Analysis
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 8, 2020
2020 journal article
Engineered Glucose Oxidase Capable of Quasi-Direct Electron Transfer after a Quick-and-Easy Modification with a Mediator
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21(3).
author keywords: glucose oxidase; direct electron transfer; amine-reactive phenazine ethosulfate; glucose sensor; glycemic level monitoring
MeSH headings : Aspergillus niger / enzymology; Biosensing Techniques / methods; Blood Glucose / analysis; Electrochemical Techniques; Fungal Proteins / metabolism; Glucose / metabolism; Glucose Oxidase / genetics; Glucose Oxidase / metabolism; Phenazines / metabolism; Protein Engineering
TL;DR:
E engineered GOx, which was made readily available for single-step modification with a redox mediator on its surface via a lysine residue rationally introduced into the enzyme, showed a quasi-DET response upon the addition of glucose.
(via Semantic Scholar)
www.mdpi.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: May 8, 2020
2020 journal article
Microraft array-based platform for sorting of viable microcolonies based on cell-lethal immunoassay of intracellular proteins in microcolony biopsies
ANALYST, 145(7), 2649–2660.
MeSH headings : Animals; Cell Line, Tumor; Humans; Image Processing, Computer-Assisted; Immunoassay / instrumentation; Immunoassay / methods; Leukemia, Basophilic, Acute / metabolism; Leukemia, Basophilic, Acute / pathology; Magnetics; Microarray Analysis; Microscopy, Fluorescence; Phosphorylation; Rats; STAT3 Transcription Factor / metabolism
TL;DR:
A quad microraft array-based platform was developed to perform semi-automated cell sampling, bioassay, and banking on ultra-small sample sizes, and has the potential to enable colony screening and sorting based on assays not compatible with cell viability, greatly expanding the cell selection criteria available to identify cells with unique phenotypes for subsequent biomedical research.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 8, 2020
2020 journal article
Wearer-Prosthesis Interaction for Symmetrical Gait: A Study Enabled by Reinforcement Learning Prosthesis Control
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING, 28(4), 904–913.
author keywords: Prosthetics; Knee; Impedance; Legged locomotion; Robot kinematics; Tuning; Wearer-prosthesis interaction; robotic knee prosthesis; reinforcement learning; gait asymmetry; anteroposterior impulse
MeSH headings : Amputees; Artificial Limbs; Biomechanical Phenomena; Gait; Humans; Knee Joint; Prosthesis Design; Walking
TL;DR:
The results suggest that it is possible to personalize transfemoral prosthesis control for improved temporal-spatial gait symmetry, and indicated that the RL-based prosthesis tuning system was a potential tool for studying wearer-prosthesis interactions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: May 8, 2020
2020 journal article
Impact of composite scaffold degradation rate on neural stem cell persistence in the glioblastoma surgical resection cavity
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 111.
author keywords: Electrospinning; Acetalated dextran; Gelatin; Tumoricidal neural stem cell therapy; TRAIL
MeSH headings : Acetylation; Animals; Brain Neoplasms / pathology; Cell Line; Cell Survival; Cross-Linking Reagents / chemistry; Dextrans / chemistry; Female; Gelatin / chemistry; Glioblastoma / pathology; Mice, Nude; Neural Stem Cells / pathology; Temperature; Tissue Scaffolds / chemistry
TL;DR:
Interestingly, scaffold degradation profile did not significantly impact NSC persistence, but persistence and long-term survival of NSCs was significantly greater for both scaffolds compared to DI, with scaffold implanted N SCs still detected by BLI at day 120 in most mice.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 8, 2020
2020 journal article
Limbs Detection and Tracking of Head-Fixed Mice for Behavioral Phenotyping Using Motion Tubes and Deep Learning
IEEE ACCESS, 8, 37891–37901.
author keywords: Tracking; Mice; Cameras; Electron tubes; Feature extraction; Training; Deep networks; motion detection; CNN; LSTM; optical flow; spatiotemporal; neuroscience; behavioral phenotyping
TL;DR:
A deep learning-based image segmentation framework to automatically extract and label limb movements from movies capturing frontal and lateral views of head-fixed mice and introduces spatio-temporal coherence to the limb segmentation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 8, 2020
2020 journal article
Antibody-mediated trapping in biological hydrogels is governed by sugar-sugar hydrogen bonds
ACTA BIOMATERIALIA, 107, 91–101.
author keywords: Biological hydrogels; Glycosylation; Antibodies; Hydrogen bonds
MeSH headings : Alginates / chemistry; Chitosan / chemistry; Hydrogels / chemistry; Hydrogen Bonding; Immunoglobulin G / immunology; Immunoglobulin G / metabolism; Immunoglobulin M / immunology; Immunoglobulin M / metabolism; Nanoparticles / chemistry; Polyethylene Glycols / chemistry; Polyethylene Glycols / metabolism; Polystyrenes / chemistry; Protein Binding; Sepharose / chemistry
TL;DR:
A model in which hydrogen bonding between carboxyl and hydroxyl groups of glycans on both Ab and matrix facilitates Ab-mediated trapping of pathogens in biogels is proposed, which offers a blueprint for designing de novo hydrogels that could harness Ab-matrix interactions for various biomedical and biological applications.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 8, 2020
2020 journal article
Interpreting Dynamic Interfacial Changes at Carbon Fiber Microelectrodes Using Electrochemical Impedance Spectroscopy
LANGMUIR, 36(15), 4214–4223.
MeSH headings : Carbon; Carbon Fiber; Dielectric Spectroscopy; Electric Impedance; Microelectrodes
TL;DR:
Electrochemical impedance spectroscopy is established as a powerful method for characterization of carbon-fiber microelectrodes, providing unprecedented insight into how real-world factors affect the electrode/solution interface.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: May 8, 2020
2020 journal article
Developing Implantable Scaffolds to Enhance Neural Stem Cell Therapy for Post-Operative Glioblastoma
MOLECULAR THERAPY, 28(4), 1056–1067.
MeSH headings : Animals; Brain Neoplasms / pathology; Brain Neoplasms / surgery; Brain Neoplasms / therapy; Cell Line, Tumor; Combined Modality Therapy; Ganciclovir / administration & dosage; Ganciclovir / pharmacology; Glioblastoma / pathology; Glioblastoma / surgery; Glioblastoma / therapy; Humans; Luminescent Measurements; Mice; Neural Stem Cells / metabolism; Neural Stem Cells / transplantation; Polyesters / chemistry; Prodrugs / administration & dosage; Prodrugs / pharmacology; Thymidine Kinase / metabolism; Tissue Scaffolds / chemistry; Treatment Outcome; Xenograft Model Antitumor Assays
TL;DR:
Design parameters for effective scaffold/tNSC composites are defined and suggest a new approach to maximizing the efficacy of tNSC therapy in human patient trials.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: April 27, 2020
2020 journal article
Modeling and Control of a Cable-Driven Rotary Series Elastic Actuator for an Upper Limb Rehabilitation Robot
FRONTIERS IN NEUROROBOTICS, 14.
author keywords: series elastic actuator (SEA); rehabilitation robot; bowden cable; torque control; impedance control; disturbance observer (DOB)
TL;DR:
The preliminary results show that this new kind of actuation can not only implement stable and friendly actuation over a long distance but also be customized to meet the requirements of other robotic system design.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: April 27, 2020
2020 journal article
Extracellular-Matrix-Anchored Click Motifs for Specific Tissue Targeting
MOLECULAR PHARMACEUTICS, 17(2), 392–403.
author keywords: drug delivery; click chemistry; pancreatic cancer; brain delivery; extracellular matrix; computer modeling
MeSH headings : Animals; Antineoplastic Agents / administration & dosage; Antineoplastic Agents / pharmacokinetics; Brain / metabolism; Cell Line, Tumor; Click Chemistry / methods; Computational Biology / methods; Computer Simulation; Disease Models, Animal; Drug Delivery Systems / methods; Esters / administration & dosage; Esters / chemistry; Esters / pharmacokinetics; Extracellular Matrix / drug effects; Female; Hydrogels / administration & dosage; Mice; Mice, Inbred C57BL; Pancreatic Neoplasms / drug therapy; Pancreatic Neoplasms / pathology; Succinimides; Tissue Distribution
TL;DR:
ECM-anchored click groups do not elicit any noticeable local or systemic toxicity or immune response and specifically capture systemically-circulating molecules at intradermal, intratumoral, and intracranial sites for multiple months.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: April 20, 2020
2020 journal article
Immigration Transition and Cognitive Symptoms During Menopausal Transition
WESTERN JOURNAL OF NURSING RESEARCH, 42(4), 269–277.
author keywords: cognition; immigration; middle aged; women; race; ethnicity
MeSH headings : Acculturation; Black or African American / statistics & numerical data; Asian / statistics & numerical data; Cognition / physiology; Emigration and Immigration; Female; Hispanic or Latino / psychology; Humans; Menopause / ethnology; Middle Aged; Surveys and Questionnaires; United States; White People / statistics & numerical data; Women's Health / ethnology
TL;DR:
The study supported significant associations between immigration transition and cognitive symptoms of women at midlife.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
5. Gender Equality
(Web of Science; OpenAlex)
Source: Web Of Science
Added: April 20, 2020
2020 journal article
Functional angiogenesis requires microenvironmental cues balancing endothelial cell migration and proliferation
LAB ON A CHIP, 20(6), 1153–1166.
MeSH headings : Cell Movement; Cell Proliferation; Cues; Endothelial Cells; Humans; Neovascularization, Pathologic; Neovascularization, Physiologic
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: April 20, 2020
2020 journal article
Microfluidics for the study of mechanotransduction
JOURNAL OF PHYSICS D-APPLIED PHYSICS, 53(22).
author keywords: microfluidics; mechanotransduction; mechanobiology; microfabrication; cell adhesion; biofluids; microdevices
TL;DR:
An overview of the main mechanotransduction pathways that function at sites of cell adhesion are given, and examples of how microfluidics can be used to apply both solid forces and fluid forces to cells are presented.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: April 20, 2020
2020 journal article
DNA looping by two 5-methylcytosine-binding proteins quantified using nanofluidic devices
EPIGENETICS & CHROMATIN, 13(1).
author keywords: DNA methylation; MeCP2; MBD2; DNA compaction
MeSH headings : 5-Methylcytosine / chemistry; 5-Methylcytosine / metabolism; Binding Sites; DNA / chemistry; DNA / metabolism; DNA Methylation; DNA-Binding Proteins / chemistry; DNA-Binding Proteins / metabolism; Epigenomics / methods; Humans; Methyl-CpG-Binding Protein 2 / chemistry; Methyl-CpG-Binding Protein 2 / metabolism; Microfluidics / instrumentation; Microfluidics / methods; Microscopy, Atomic Force / methods; Protein Binding
TL;DR:
It is demonstrated that ATTO 565-labeled MBD2 is a good candidate as a staining agent for epigenetic mapping and determined that the mechanism for compaction by MeCP2 is the formation of bridges between distant DNA stretches and theformation of loops.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: April 20, 2020
2020 journal article
Object Shape and Surface Topology Recognition Using Tactile Feedback Evoked through Transcutaneous Nerve Stimulation
IEEE TRANSACTIONS ON HAPTICS, 13(1), 152–158.
author keywords: Shape recognition; surface topology; tactile sensation; transcutaneous nerve stimulation
MeSH headings : Adult; Feedback, Sensory / physiology; Female; Fingers / physiology; Humans; Male; Median Nerve / physiology; Recognition, Psychology / physiology; Touch / physiology; Touch Perception / physiology; Transcutaneous Electric Nerve Stimulation; Ulnar Nerve / physiology; Young Adult
TL;DR:
It is suggested that tactile feedback evoked from transcutaneous nerve stimulation allows the recognition of object shape and surface topology, which may help improve object manipulation and promote fine control of a prosthetic hand.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: April 14, 2020
2020 journal article
A Face-Shear Mode Piezoelectric Array Sensor for Elasticity and Force Measurement
SENSORS, 20(3).
author keywords: piezoelectric array sensor; elasticity sensor; force sensor; face-shear mode; PMN-PT
TL;DR:
The 6 × 6 piezoelectric array sensor employs an impedance measurement technique, sensing the acoustic load impedance of a target by measuring the electrical impedance shift of face-shear mode PMN–PT (lead magnesium niobate–lead titanate) single crystal elements.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
7. Affordable and Clean Energy
(OpenAlex)
Source: Web Of Science
Added: April 14, 2020
2020 journal article
An off-the-shelf artificial cardiac patch improves cardiac repair after myocardial infarction in rats and pigs
Science Translational Medicine, 12(538).
MeSH headings : Animals; Cell- and Tissue-Based Therapy; Extracellular Matrix; Heart; Myocardial Infarction / therapy; Myocardium; Rats; Swine
TL;DR:
The artCP is a clinically feasible, easy-to-store, and cell-free alternative to myocardial repair using cell-based cardiac patches and supported cardiac recovery by reducing scarring, promoting angiomyogenesis, and boosting cardiac function.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: April 9, 2020
2020 journal article
Shorter gastrocnemius fascicle lengths in older adults associate with worse capacity to enhance push-off intensity in walking
GAIT & POSTURE, 77, 89–94.
author keywords: Ultrasound; Plantarflexor; Triceps surae; Elderly; Gait; Biomechanics
MeSH headings : Adult; Age Factors; Aged; Biomechanical Phenomena; Female; Gait / physiology; Humans; Leg / diagnostic imaging; Leg / physiology; Leg / physiopathology; Male; Muscle, Skeletal / diagnostic imaging; Muscle, Skeletal / physiology; Muscle, Skeletal / physiopathology; Self-Help Devices; Tendons / physiology; Ultrasonography; Walking / physiology; Young Adult
TL;DR:
These findings provide muscle-level insight to develop more effective rehabilitation techniques to improve push-off intensity in older adults and assistive technologies designed to steer plantarflexor muscle fascicle operating behavior during functional tasks.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: April 6, 2020
2020 journal article
Home-based Upper Extremity Stroke Therapy Using a Multiuser Virtual Reality Environment: A Randomized Trial
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION, 101(2), 196–203.
author keywords: Rehabilitation; Stroke; Telerehabilitation; Upper extremity; Virtual reality
MeSH headings : Adult; Aged; Cross-Over Studies; Female; Home Care Services; Humans; Male; Middle Aged; Motivation; Recovery of Function; Stroke Rehabilitation / methods; Telerehabilitation / methods; Upper Extremity / physiology; Video Games; Virtual Reality
TL;DR:
Multi-user VR exercises may provide an effective means of extending clinical therapy into the home, and Fugl-Meyer Upper-Extremity (FMUE) score improved significantly across all participants, and Intrinsic Motivation Inventory (IMI) scores.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: March 30, 2020
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