Works Published in 2020
Displaying works 101 - 120 of 131 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2020 journal article
Extending the fused-sphere SAFT-gamma Mie force field parameterization approach to poly(vinyl butyral) copolymers
JOURNAL OF CHEMICAL PHYSICS, 152(4).
TL;DR:
This study explores the application of the fused-sphere SAFT-γ Mie approach to copolymers and demonstrates its capabilities at modeling poly(vinyl alcohol-co-vinyl butyral) (PVB), an important commercial copolymer widely used as an interlayer in laminated safety glass applications.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: April 6, 2020
2020 journal article
Transcriptome Ortholog Alignment Sequence Tools (TOAST) for phylogenomic dataset assembly
BMC Evolutionary Biology, 20(1).
author keywords: BUSCO ortholog assembly; Cetacean and teleost fish phylogeny; Missing data visualization; Transcriptome; Concatenated alignment
MeSH headings : Animals; Datasets as Topic; Humans; Phylogeny; Sequence Alignment / methods; Software; Transcriptome
TL;DR:
ToAST is introduced, an open source R software package that can utilize the ortholog searches based on the software Benchmarking Universal Single-Copy Orthologs to assemble multiple sequence alignments of orthologous loci from transcriptomes for any group of organisms.
(via Semantic Scholar)
bmcevolbiol.biomedcentral.com (publisher PDF)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: ORCID
Added: March 31, 2020
2020 journal article
Tumor cell-derived exosomes home to their cells of origin and can be used as Trojan horses to deliver cancer drugs
THERANOSTICS, 10(8), 3474–3487.
author keywords: exosome; homing; integrin; doxorubicin; cancer therapy
MeSH headings : Animals; Antibiotics, Antineoplastic / administration & dosage; Antineoplastic Agents / administration & dosage; Cell Line, Tumor; Doxorubicin / administration & dosage; Doxorubicin / analogs & derivatives; Drug Delivery Systems; Exosomes / metabolism; HeLa Cells; Humans; Mice; Mice, Nude; Polyethylene Glycols / administration & dosage
TL;DR:
It is demonstrated that the exosomes' ability to target the parent cancer is a phenomenon that opens up new ways to devise targeted therapies to deliver anti-tumor drugs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: March 30, 2020
2020 journal article
Comparative Plasma and Interstitial Fluid Pharmacokinetics of Meloxicam, Flunixin, and Ketoprofen in Neonatal Piglets
FRONTIERS IN VETERINARY SCIENCE, 7.
author keywords: piglet; pain; welfare; castration; NSAID; pharmacokinetics; interstitial fluid
TL;DR:
If drug concentrations in the ISF are more closely related to efficacy than the plasma, then the delay between the Tmax in plasma and ISF may be relevant to the timing of castration in order to provide the greatest analgesic effect.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: March 30, 2020
2020 journal article
Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis
NATURE COMMUNICATIONS, 11(1).
MeSH headings : Administration, Inhalation; Alveolar Epithelial Cells / drug effects; Alveolar Epithelial Cells / metabolism; Alveolar Epithelial Cells / pathology; Animals; Apoptosis / drug effects; Bleomycin / toxicity; Cell Proliferation; Disease Models, Animal; Exosomes / metabolism; Exosomes / transplantation; Humans; Idiopathic Pulmonary Fibrosis / chemically induced; Idiopathic Pulmonary Fibrosis / metabolism; Idiopathic Pulmonary Fibrosis / pathology; Idiopathic Pulmonary Fibrosis / therapy; Lung / cytology; Lung / metabolism; Lung Injury / chemically induced; Lung Injury / metabolism; Lung Injury / pathology; Lung Injury / therapy; Mesenchymal Stem Cells / metabolism; Mice; Myofibroblasts / cytology; Proteomics; Silicon Dioxide / toxicity; Spheroids, Cellular / metabolism
TL;DR:
It is shown that the secretome and exosomes of lung spheroid cells is effective as inhalation treatment in rodent models of lung injury and fibrosis and superior to the counterparts derived from mesenchymal stem cells.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: March 23, 2020
2020 journal article
Effect of presurgical storage conditions on leakage pressures of enterotomy sites closed with unidirectional barbed suture material in fresh, chilled, and frozen-thawed cadaveric canine jejunal specimens
AMERICAN JOURNAL OF VETERINARY RESEARCH, 81(3), 220–226.
MeSH headings : Anastomosis, Surgical / veterinary; Animals; Cadaver; Dogs; Freezing; Pressure; Sutures
TL;DR:
Leak pressure testing of cadaveric jejunal segments that are fresh or chilled at 4°C for 24 hours is recommended for enterotomy studies involving barbed suture material in dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: March 23, 2020
2020 journal article
Joint laxity varies in response to partial and complete anterior cruciate ligament injuries throughout skeletal growth
JOURNAL OF BIOMECHANICS, 101.
author keywords: Anterior cruciate ligament; Pediatric; Injury; Joint mechanics; Animal model
MeSH headings : Animals; Anterior Cruciate Ligament Injuries / complications; Biomechanical Phenomena; Female; Joint Instability / complications; Joint Instability / physiopathology; Rotation; Stifle / growth & development; Stifle / physiopathology; Swine
TL;DR:
At all ages, the medial collateral ligament and the medial meniscus combined to resist the majority of applied anterior tibial load following complete ACL transection, adding to the current understanding of age-specific functional properties of both healthy and injured knees during skeletal growth.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: March 23, 2020
2020 journal article
Nanosilver composite pNIPAm microgels for the development of antimicrobial platelet-like particles
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 108(6), 2599–2609.
Contributors: E. Chee n, S. Nandi n, K. Nellenbach n, E. Mihalko n, D. Snider n, L. Morrill n, A. Bond n, E. Sproul n
author keywords: antimicrobial; microgels; nanosilver; platelet-mimetic; wound healing
MeSH headings : Acrylic Resins / chemistry; Animals; Anti-Infective Agents / chemistry; Anti-Infective Agents / pharmacology; Bacterial Infections / drug therapy; Bacterial Infections / microbiology; Blood Platelets; Clot Retraction; Colony-Forming Units Assay; Fibrin / chemistry; Fibrin / immunology; Gels; Hemorrhage / drug therapy; Hemostasis / drug effects; Liver / injuries; Male; Metal Nanoparticles; Mice; Mice, Inbred C57BL; Microgels; Silver / administration & dosage; Silver / chemistry; Wound Healing
TL;DR:
It is found that nanosilver incorporation does not affect base PLP performance while bestowing significant antimicrobial activity and enhancing infected wound healing outcomes, and Ag-PLPs have great promise for treating hemorrhage and improving healing following trauma.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: March 16, 2020
2020 journal article
Use of intravenous lipid therapy in a cat with carprofen overdose
CLINICAL CASE REPORTS, 8(4), 653–657.
author keywords: feline toxicosis; intravenous lipids; NSAID overdose
TL;DR:
It is postulates that ILE can be used for the treatment of carprofen toxicity in cats and supports the lipid sink theory as the main mechanism of action.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: March 16, 2020
2020 journal article
Differential contribution of sensory transient receptor potential channels in response to the bioactive lipid sphingosine-1-phosphate
MOLECULAR PAIN, 16.
author keywords: Itch; pain; sphingosine 1-phosphate; TRPA1; TRPV1
MeSH headings : Animals; Behavior, Animal; Calcium / metabolism; Cells, Cultured; Female; Gene Expression Regulation; Lysophospholipids / chemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pruritus / drug therapy; Sensory Receptor Cells / metabolism; Sphingosine / analogs & derivatives; Sphingosine / chemistry; TRPA1 Cation Channel / metabolism; TRPV Cation Channels / metabolism
TL;DR:
It is revealed that S1P induces both pain and itch in vivo and that these responses are partially dependent upon the TRPV1, but not TRPA1 channels.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: March 16, 2020
2020 journal article
Atorvastatin enhances the therapeutic efficacy of mesenchymal stem cells-derived exosomes in acute myocardial infarction via up-regulating long non-coding RNA H19
CARDIOVASCULAR RESEARCH, 116(2), 353–367.
author keywords: Exosomes; Atorvastatin; MSCs; lncRNA H19; Myocardial infarction
MeSH headings : Angiogenic Proteins / metabolism; Animals; Apoptosis; Atorvastatin / pharmacology; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Endothelial Cells / metabolism; Endothelial Cells / pathology; Exosomes / drug effects; Exosomes / metabolism; Exosomes / transplantation; Female; Humans; Inflammation Mediators / metabolism; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells / drug effects; Mesenchymal Stem Cells / metabolism; Myocardial Infarction / genetics; Myocardial Infarction / metabolism; Myocardial Infarction / physiopathology; Myocardial Infarction / surgery; Myocytes, Cardiac / metabolism; Myocytes, Cardiac / pathology; Neovascularization, Physiologic; RNA, Long Noncoding / genetics; RNA, Long Noncoding / metabolism; Rats, Sprague-Dawley; Recovery of Function; Up-Regulation; Ventricular Function, Left
TL;DR:
Exosomes obtained from ATV-pretreated MSCs have significantly enhanced therapeutic efficacy for treatment of AMI possibly through promoting endothelial cell function and mediates the cardioprotective roles of MSCATV-Exo in promoting angiogenesis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: March 10, 2020
2020 journal article
Draft Genome Sequence of Staphylococcus pseudintermedius Strain 13-13613, Isolated from a Case of Canine Pyoderma
MICROBIOLOGY RESOURCE ANNOUNCEMENTS, 9(7).
TL;DR:
The draft genome sequence of Staphylococcus pseudintermedius strain 13-13613, isolated from a case of canine pyoderma, contains 2,533,486 bp in 570 contigs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: March 10, 2020
2020 journal article
Targeted anti-IL-1 beta platelet microparticles for cardiac detoxing and repair
SCIENCE ADVANCES, 6(6).
MeSH headings : Animals; Apoptosis; Blood Platelets / metabolism; Cell-Derived Microparticles / metabolism; Cytokines / metabolism; Disease Models, Animal; Humans; Immunohistochemistry; Inflammation Mediators / metabolism; Interleukin-1beta / antagonists & inhibitors; Mice; Models, Biological; Myocardial Infarction / etiology; Myocardial Infarction / metabolism; Myocardial Infarction / pathology; Myocytes, Cardiac / metabolism; Protein Binding; Ventricular Remodeling
TL;DR:
IL1-PM is a promising cardiac detoxification agent that removes cytotoxic IL-1β during AMI and induces therapeutic cardiac repair and protects the cardiomyocytes from apoptosis by neutralizing IL–1β and decreasing IL- 1β–driven caspase-3 activity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: March 2, 2020
2020 journal article
Determination of the minimum alveolar concentration of sevoflurane that blunts adrenergic responses and the effect of a constant rate infusion of ketamine in sheep
RESEARCH IN VETERINARY SCIENCE, 128, 230–235.
author keywords: Ketamine; MAC-BAR; sevoflurane; sheep; sparing effect
MeSH headings : Adrenergic Agents / administration & dosage; Adrenergic Agents / pharmacology; Anesthesia / veterinary; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Cross-Over Studies; Drug Synergism; Female; Ketamine / administration & dosage; Ketamine / blood; Ketamine / pharmacology; Pulmonary Alveoli / chemistry; Pulmonary Alveoli / drug effects; Sevoflurane / administration & dosage; Sevoflurane / adverse effects; Sevoflurane / pharmacokinetics; Sheep
TL;DR:
The MAC-BAR of sevoflurane in sheep was determined and the effect of higher doses of ketamine on inhalational anesthetic agents and their potential adverse effects are warranted.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Web Of Science
Added: February 27, 2020
2020 journal article
Effect of diphenhydramine and cetirizine on immediate and late-phase cutaneous allergic reactions in healthy dogs: a randomized, double-blinded crossover study
VETERINARY DERMATOLOGY, 31(4), 256-+.
MeSH headings : Animals; Cetirizine / therapeutic use; Cross-Over Studies; Diphenhydramine / therapeutic use; Dog Diseases / drug therapy; Dogs; Double-Blind Method; Histamine / administration & dosage; Histamine H1 Antagonists / administration & dosage; Hypersensitivity / drug therapy; Hypersensitivity / veterinary; Male; Skin / drug effects; Skin / pathology; Skin Tests; p-Methoxy-N-methylphenethylamine / administration & dosage
TL;DR:
Oral cetirizine was effective in preventing cutaneous allergic reactions without any obvious adverse effects in dogs and oral DPH failed to show an inhibitory effect despite attaining plasma drug concentrations that are considered effective in people.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 27, 2020
2020 journal article
Association of fecal sample collection technique and treatment history with Tritrichomonas foetus polymerase chain reaction test results in 1717 cats
JOURNAL OF VETERINARY INTERNAL MEDICINE, 34(2), 734–741.
author keywords: diarrhea; retrospective; risk factors; ronidazole
MeSH headings : Animals; Antiprotozoal Agents / therapeutic use; Cat Diseases / diagnosis; Cat Diseases / drug therapy; Cat Diseases / parasitology; Cats; Feces / parasitology; Female; Male; Polymerase Chain Reaction / veterinary; Protozoan Infections, Animal / diagnosis; Protozoan Infections, Animal / drug therapy; Protozoan Infections, Animal / parasitology; Retrospective Studies; Ronidazole / therapeutic use; Specimen Handling / veterinary; Tritrichomonas foetus / isolation & purification; United States
TL;DR:
Results of this study support that fecal samples collected by loop might be better for PCR diagnosis of T. foetus infection and Lack of association of ronidazole with PCR test results and a 21% all‐potential‐causes failure rate of rONidazoles in cats with preconfirmed infection are important limitations to use of this drug.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: February 27, 2020
2020 journal article
Ependyma-expressed CCN1 restricts the size of the neural stem cell pool in the adult ventricular-subventricular zone
EMBO JOURNAL, 39(5).
author keywords: CCN1; EGFR; ependymal cells; neural stem cells; niche
MeSH headings : Adult Stem Cells / physiology; Animals; Brain; Cysteine-Rich Protein 61 / genetics; Cysteine-Rich Protein 61 / metabolism; Ependyma / cytology; Ependyma / metabolism; ErbB Receptors / genetics; ErbB Receptors / metabolism; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Stem Cells / cytology; Neural Stem Cells / metabolism; Neurogenesis / physiology; Signal Transduction
TL;DR:
It is shown that ependyma‐derived matricellular protein CCN1 (cellular communication network factor 1) negatively regulates niche capacity and NSC number in the adult ventricular–subventricular zone (V‐SVZ) of the adult brain to maintain the proper niche capacity of the V‐VZ.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: February 17, 2020
2020 journal article
Minimally invasive spine surgery in dogs: Evaluation of the safety and feasibility of a thoracolumbar approach to the spinal cord
VETERINARY SURGERY, 49, O76–O85.
MeSH headings : Animals; Dogs / surgery; Feasibility Studies; Female; Male; Minimally Invasive Surgical Procedures / methods; Minimally Invasive Surgical Procedures / veterinary; Orthopedic Procedures / veterinary; Pain, Postoperative / veterinary; Prospective Studies; Plastic Surgery Procedures; Spinal Cord / surgery; Thoracic Vertebrae / surgery; Treatment Outcome
TL;DR:
Minimally invasive spine surgery was a safe and feasible technique to access the thoracolumbar vertebral canal and the ventral aspect of the spinal cord in dogs and supported postoperative pain benefits.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: February 17, 2020
2020 journal article
Perceptions and attitudes of Small Animal Internal Medicine specialists toward the publication requirement for board certification
JOURNAL OF VETERINARY INTERNAL MEDICINE, 34(2), 574–580.
author keywords: board certification; credentials; education; residency training
MeSH headings : Authorship; Certification; Humans; Societies, Scientific / organization & administration; Societies, Scientific / standards; Specialization; Specialty Boards / standards; Veterinary Medicine / organization & administration; Veterinary Medicine / standards
TL;DR:
A majority of SAIM Diplomates favored the retention of the publication requirement in some form, and publications submitted for credentialing purposes were cited at rates similar to control articles.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: February 17, 2020
2020 journal article
Population pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin in clinically diseased or injured Eastern box turtles (Terrapene carolina carolina), yellow‐bellied sliders (Trachemys scripta scripta), and river cooters (Pseudemys concinna)
Journal of Veterinary Pharmacology and Therapeutics.
author keywords: ciprofloxacin; enrofloxacin; population; subcutaneous injection; turtles
MeSH headings : Animals; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / metabolism; Anti-Bacterial Agents / pharmacokinetics; Area Under Curve; Ciprofloxacin / blood; Ciprofloxacin / metabolism; Ciprofloxacin / pharmacokinetics; Enrofloxacin / blood; Enrofloxacin / metabolism; Enrofloxacin / pharmacokinetics; Female; Half-Life; Injections, Subcutaneous; Male; Turtles / blood
TL;DR:
Results indicate variable pharmacokinetic parameters for enrofloxacin among turtle species, which will help guide appropriate dosing protocols in injured turtles.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: February 13, 2020
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