Works Published in 2006
Displaying works 41 - 60 of 96 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2006 journal article
Pharmacokinetics of voriconazole after oral and intravenous administration to horses
AMERICAN JOURNAL OF VETERINARY RESEARCH, 67(6), 1070–1075.
MeSH headings : Administration, Oral; Animals; Antifungal Agents / administration & dosage; Antifungal Agents / blood; Antifungal Agents / pharmacokinetics; Biological Availability; Chemistry, Pharmaceutical; Cross-Over Studies; Drug Stability; Female; Horses / blood; Injections, Intravenous; Male; Pyrimidines / administration & dosage; Pyrimidines / blood; Pyrimidines / pharmacokinetics; Triazoles / administration & dosage; Triazoles / blood; Triazoles / pharmacokinetics; Voriconazole
TL;DR:
It was concluded that administration of voriconazole at a dosage of 4 mg/kg, PO, every 24 hours will attain plasma concentrations adequate for treatment of horses with fungal infections for which the fungi have a minimum inhibitory concentration.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2006 journal article
Pharmacokinetics of fluconazole after oral administration of single and multiple doses in African grey parrots
AMERICAN JOURNAL OF VETERINARY RESEARCH, 67(3), 417–422.
MeSH headings : Absorption; Administration, Oral; Animals; Antifungal Agents / administration & dosage; Antifungal Agents / blood; Antifungal Agents / pharmacokinetics; Area Under Curve; Dose-Response Relationship, Drug; Fluconazole / administration & dosage; Fluconazole / blood; Fluconazole / pharmacokinetics; Half-Life; Parrots / metabolism; Suspensions; Tablets
TL;DR:
Oral administration of fluconazole to parrots at 10 to 20 mg/kg every 24 to 48 hours maintains plasma concentrations above the minimum inhibitory concentration for several common yeast species.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2006 journal article
Pharmacokinetics of florfenicol after a single intramuscular dose in white-spotted bamboo sharks (Chiloscyllium plagiosum)
JOURNAL OF ZOO AND WILDLIFE MEDICINE, 37(2), 165–173.
author keywords: bamboo shark; Chiloscyllium plagiosum; florfenicol; pharmacokinetics; meningitis
MeSH headings : Animals; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / cerebrospinal fluid; Anti-Bacterial Agents / pharmacokinetics; Area Under Curve; Chromatography, High Pressure Liquid / methods; Chromatography, High Pressure Liquid / veterinary; Dose-Response Relationship, Drug; Female; Half-Life; Injections, Intramuscular / veterinary; Male; Meningitis, Bacterial / drug therapy; Meningitis, Bacterial / veterinary; Microbial Sensitivity Tests / veterinary; Pilot Projects; Sharks / blood; Sharks / metabolism; Thiamphenicol / analogs & derivatives; Thiamphenicol / blood; Thiamphenicol / cerebrospinal fluid; Thiamphenicol / pharmacokinetics
TL;DR:
The pharmacokinetics of florfenicol in the white-spotted bamboo shark was evaluated and the potential application for treatment of bacterial meningitis was explored.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2006 journal article
Magnetic resonance imaging findings in a dog with caudal aortic thromboembolism and ischemic myopathy
VETERINARY RADIOLOGY & ULTRASOUND, 47(4), 334–338.
MeSH headings : Animals; Aorta, Thoracic / pathology; Aortic Diseases / complications; Aortic Diseases / pathology; Aortic Diseases / veterinary; Diagnosis, Differential; Dog Diseases / pathology; Dogs; Magnetic Resonance Imaging / veterinary; Male; Paresis / etiology; Paresis / veterinary; Thromboembolism / complications; Thromboembolism / pathology; Thromboembolism / veterinary
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Dermatological effects of chronic exposure to 7,12-dimethylbenz[a]anthracene (DMBA) or N-methyl-N-nitrosoguanidine (MNNG) in swine
CUTANEOUS AND OCULAR TOXICOLOGY, 25(2), 103–119.
author keywords: DMBA; MNNG; skin cancer; swine
MeSH headings : 9,10-Dimethyl-1,2-benzanthracene / toxicity; Analysis of Variance; Animals; Cocarcinogenesis; Female; Methylnitronitrosoguanidine / toxicity; Neoplasms, Radiation-Induced; Skin / drug effects; Skin / radiation effects; Skin Neoplasms / chemically induced; Swine; Ultraviolet Rays
TL;DR:
The findings show that although chronic exposure to MNNG and DMBA, with or without UVB exposure, caused severe to mild dermatopathological changes, neither resulted in the development of skin carcinomas.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Bilateral renal agenesis in an alpaca cria
Canadian Veterinary Journal, 47(2), 159–161.
Source: NC State University Libraries
Added: August 6, 2018
2006 journal article
A quantitative real-time RT-PCR assay to measure TGF-beta mRNA and its correlation with hematologic, plasma chemistry and organo-somatic indices responses in triamcinolone-treated Atlantic menhaden, Brevoortia tyrannus
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 30(5), 473–484.
author keywords: Atlantic menhaden; triamcinolone; TGF-beta; health indices; hematology; plasma chemistry; real-time RT-PCR
MeSH headings : Animals; Anti-Inflammatory Agents / pharmacology; Base Sequence; Blood Glucose / analysis; Fish Diseases / blood; Fish Diseases / immunology; Fish Diseases / metabolism; Fishes / blood; Fishes / immunology; Fishes / metabolism; Leukocytes, Mononuclear / drug effects; Leukocytes, Mononuclear / metabolism; Liver / drug effects; Liver / metabolism; Molecular Sequence Data; Plasma; RNA, Messenger / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Skin Ulcer / immunology; Skin Ulcer / metabolism; Skin Ulcer / veterinary; Spleen / drug effects; Spleen / metabolism; Transforming Growth Factor beta / metabolism; Triamcinolone Acetonide / pharmacology
TL;DR:
A quantitative real-time reverse transcription polymerase chain reaction (RT-PCR) assay was developed to measure transforming growth factor-beta (TGF-beta) in Atlantic menhaden, an estuarine-dependent species plagued by ulcerative skin lesions in the estuaries along the eastern United States.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
A peptide against the N-terminus of myristoylated alanine-rich C kinase substrate inhibits degranulation of human leukocytes in vitro
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 34(6), 647–652.
author keywords: MARCKS protein; leukocytes; degranulation
MeSH headings : Cell Degranulation; Cell Line; Dose-Response Relationship, Drug; Eosinophil Peroxidase / metabolism; Granzymes; HL-60 Cells; Humans; Killer Cells, Natural; Leukocytes / drug effects; Leukocytes / enzymology; Leukocytes / physiology; Muramidase / metabolism; Neutrophils; Peptide Fragments / pharmacology; Peroxidase / metabolism; Serine Endopeptidases / metabolism; Tetradecanoylphorbol Acetate; Time Factors; U937 Cells
TL;DR:
The results indicate that MARCKS protein may play an important role in the secretion of membrane-bound granules from different leukocytes, and may be an important component of secretory pathways associated with release of granules by different cell types.
(via Semantic Scholar)
europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Phase I trial of doxorubicin-containing low temperature sensitive liposomes in spontaneous canine tumors
CLINICAL CANCER RESEARCH, 12(13), 4004–4010.
MeSH headings : Animals; Antineoplastic Agents / administration & dosage; Antineoplastic Agents / adverse effects; Antineoplastic Agents / pharmacokinetics; Carcinoma / therapy; Carcinoma / veterinary; Combined Modality Therapy; Dog Diseases / therapy; Dogs; Dose-Response Relationship, Drug; Doxorubicin / administration & dosage; Doxorubicin / adverse effects; Doxorubicin / pharmacokinetics; Drug Administration Schedule; Drug Delivery Systems; Female; Hyperthermia, Induced / methods; Liposomes; Male; Maximum Tolerated Dose; Microwaves / therapeutic use; Sarcoma / therapy; Sarcoma / veterinary; Temperature; Treatment Outcome
TL;DR:
LTSL-doxorubicin offers a novel approach to improving drug delivery to solid tumors and was well tolerated and resulted in favorable response profiles in these patients.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Neutrophils do not mediate the pathophysiological sequelae of Cryptosporidium parvum infection in neonatal piglets
INFECTION AND IMMUNITY, 74(10), 5497–5505.
MeSH headings : Animals; Antibodies / pharmacology; CD18 Antigens / drug effects; Cryptosporidiosis / immunology; Cryptosporidiosis / pathology; Cryptosporidium parvum; Diarrhea / immunology; Diarrhea / microbiology; Disease Models, Animal; Ileum / immunology; Ileum / microbiology; Ileum / pathology; Immunoglobulin G / pharmacology; Intestinal Mucosa / immunology; Intestinal Mucosa / microbiology; Intestinal Mucosa / pathology; Lipid Peroxidation; Neutrophils / enzymology; Neutrophils / immunology; Peroxidase / analysis; Peroxidase / metabolism; Peroxynitrous Acid / metabolism; Prostaglandins / metabolism; Superoxides / metabolism; Swine
TL;DR:
These studies are the first to demonstrate that neutrophilic inflammation arising in response to infection by a noninvasive epithelial pathogen results in physiologic rather than pathological effects in vivo.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2006 journal article
Lens epithelial cells synthesize and secrete ceruloplasmin: Effects of ceruloplasmin and transferrin on iron efflux and intracellular iron dynamics
EXPERIMENTAL EYE RESEARCH, 83(4), 721–727.
author keywords: lens; ceruloplasmin; iron; ferritin; transferrin; labile iron pool
MeSH headings : Animals; Ceruloplasmin / biosynthesis; Ceruloplasmin / pharmacology; Ceruloplasmin / physiology; Culture Media, Conditioned; Cytosol / metabolism; Dogs; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Ferritins / metabolism; Iron / metabolism; Lens Capsule, Crystalline / cytology; Lens Capsule, Crystalline / drug effects; Lens Capsule, Crystalline / metabolism; Tissue Culture Techniques; Transferrin / biosynthesis; Transferrin / pharmacology; Transferrin / physiology
TL;DR:
An important role for ceruloplasmin and transferrin in iron metabolism in the lens is indicated, with results consistent with increased efflux of iron.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Immune-related, lectin-like receptors are differentially expressed in the myeloid and lymphoid lineages of zebrafish
Immunogenetics, 58(1), 31–40.
author keywords: C-type lectin; ITIM; natural killer cells; signaling motifs
MeSH headings : Amino Acid Sequence; Animals; Cell Survival / physiology; Chromosomes; Chromosomes, Artificial, Bacterial; Killer Cells, Natural / metabolism; Lectins, C-Type / chemistry; Lectins, C-Type / genetics; Lectins, C-Type / metabolism; Lectins, C-Type / physiology; Lymphocytes / metabolism; Models, Molecular; Molecular Sequence Data; Myeloid Cells / metabolism; Phylogeny; Zebrafish / genetics; Zebrafish / immunology; Zebrafish / metabolism; Zebrafish Proteins / genetics; Zebrafish Proteins / metabolism
TL;DR:
A multi-gene family of Group II immune-related, lectin-like receptors (illrs) whose members possess inhibiting and/or activating signaling motifs typical of Group V NK receptors are identified.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2006 journal article
Evaluation of the gross and histologic reactions to five commonly used suture materials in the skin of the African clawed frog (Xenopus laevis)
Journal of the American Association for Laboratory Animal Science, 45(6), 22–26.
Source: NC State University Libraries
Added: August 6, 2018
2006 journal article
Desmoglein-1 is a minor autoantigen in dogs with pemphigus foliaceus
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 110(3-4), 245–255.
author keywords: autoimmunity; blistering; canine; cadherin; desmosome; skin
MeSH headings : Animals; Autoantibodies / immunology; Autoantigens / immunology; Calcium / metabolism; Cell Line; Desmoglein 1 / immunology; Dog Diseases / immunology; Dogs; Glycosylation; Humans; Pemphigus / immunology; Pemphigus / veterinary
TL;DR:
These studies establish canine dsg1 as a minor autoantigen for canine PF, and antigenic epitopes appear to be conformation- and glycosylation-dependent.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Compartmentalization and evolution of feline immunodeficiency virus between the central nervous system and periphery following intracerebroventricular or systemic inoculation
JOURNAL OF NEUROVIROLOGY, 12(4), 307–321.
author keywords: brain; cerebrospinal fluid; dementia; evolution; heteroduplex tracking assay; HIV
MeSH headings : Animals; Brain / virology; Cats; Central Nervous System Diseases / blood; Central Nervous System Diseases / cerebrospinal fluid; Central Nervous System Diseases / virology; Feline Acquired Immunodeficiency Syndrome / blood; Feline Acquired Immunodeficiency Syndrome / cerebrospinal fluid; Feline Acquired Immunodeficiency Syndrome / virology; Genes, env; Heteroduplex Analysis; Immunodeficiency Virus, Feline / genetics; Immunodeficiency Virus, Feline / metabolism; Leukocytes, Mononuclear / virology; Peripheral Nervous System Diseases / blood; Peripheral Nervous System Diseases / cerebrospinal fluid; Peripheral Nervous System Diseases / virology; RNA, Viral / blood; RNA, Viral / cerebrospinal fluid
TL;DR:
Early changes in virus evolution and compartmentalization between peripheral tissues and the central nervous system (CNS) after intracerebroventricular or intraperitoneal inoculation of animals with cell-free feline immunodeficiency virus (FIV) were tracked.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Cerebrospinal fluid is an efficient route for establishing brain infection with feline immunodeficiency virus and transfering infectious virus to the periphery
JOURNAL OF NEUROVIROLOGY, 12(4), 294–306.
author keywords: dementia; HIV; macrophages; T cells; viremia
MeSH headings : Animals; Brain Diseases / cerebrospinal fluid; Brain Diseases / immunology; Brain Diseases / virology; Cats; DNA, Viral / isolation & purification; Feline Acquired Immunodeficiency Syndrome / cerebrospinal fluid; Feline Acquired Immunodeficiency Syndrome / immunology; Feline Acquired Immunodeficiency Syndrome / virology; Immunodeficiency Virus, Feline / genetics; Immunodeficiency Virus, Feline / isolation & purification; Lymphocyte Subsets / immunology; Macrophages / immunology; Macrophages / virology; RNA, Viral / blood; RNA, Viral / cerebrospinal fluid; Viral Load
TL;DR:
Results indicate that free FIV circulating in the CSF promotes infection of the CNS and provides a highly efficient pathway for the transfer of infectious virus to the periphery.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2006 article
What is your diagnosis?
Pierce, K. N., & Gerard, M. P. (2006, July 1). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 229, pp. 37–38.
MeSH headings : Accidental Falls; Animals; Diagnosis, Differential; Fractures, Bone / diagnostic imaging; Fractures, Bone / veterinary; Horses / injuries; Lameness, Animal / etiology; Male; Pelvic Bones / diagnostic imaging; Pelvic Bones / injuries; Radionuclide Imaging; Ultrasonography
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Role of mTOR signaling in intestinal cell migration
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 291(3), G510–G517.
author keywords: insulin-like growth factor-1; arginine; p70 s6 kinase; extracellular signal-regulated kinase-2; rapamycin
MeSH headings : Animals; Arginine / metabolism; Cell Line; Cell Movement / physiology; Intestinal Mucosa / cytology; Intestinal Mucosa / physiology; Intestines / physiology; Protein Kinases / metabolism; Rats; Signal Transduction / physiology; TOR Serine-Threonine Kinases
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Mucosal permeability of water-soluble drugs in the equine jejunum: a preliminary investigation
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 29(5), 379–385.
MeSH headings : Animals; Anti-Infective Agents / chemistry; Anti-Infective Agents / pharmacokinetics; Anti-Infective Agents / pharmacology; Biological Availability; Cephalexin / chemistry; Cephalexin / pharmacokinetics; Fluconazole / chemistry; Fluconazole / pharmacokinetics; Fluoroquinolones / chemistry; Fluoroquinolones / pharmacokinetics; Horses; Intestinal Mucosa / drug effects; Jejunum / metabolism; Linear Models; Metronidazole / chemistry; Metronidazole / pharmacokinetics; Permeability / drug effects; Quinolones / chemistry; Quinolones / pharmacokinetics; Solubility
TL;DR:
The Ussing chamber is a promising method for determining mucosal permeability in the horse and the low permeability of cephalexin across the tissue may indicate a lack of active transporters that are found in other species.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2006 journal article
Heparin and fibroblast growth factors affect surfactant protein gene expression in type II cells
American Journal of Respiratory Cell and Molecular Biology, 35(5), 611–618.
Source: NC State University Libraries
Added: August 6, 2018
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