Works Published in 2020
Displaying works 101 - 120 of 216 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2020 journal article
Influence of barbed epitendinous suture combined with a core locking-loop sutures to repair experimental flexor tendon lacerations
VETERINARY SURGERY, 49(8), 1590–1599.
MeSH headings : Animals; Cadaver; Dogs / injuries; Dogs / surgery; Lacerations / surgery; Lacerations / veterinary; Plastic Surgery Procedures / veterinary; Suture Techniques / veterinary; Sutures / veterinary; Tendon Injuries / surgery; Tendon Injuries / veterinary; Tendons / surgery; Tensile Strength
TL;DR:
Investigating the influence of barbed epitendinous sutures on the biomechanical properties and gap formation of repaired canine tendons found Stratafix barbed suture performed better as an ES compared with other barbedSutures and similarly to monofilament suture.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: September 28, 2020
2020 review
VISUALIZATION OF MICROVASCULAR ANGIOGENESIS USING DUAL-FREQUENCY CONTRAST-ENHANCED ACOUSTIC ANGIOGRAPHY: A REVIEW
[Review of ]. ULTRASOUND IN MEDICINE AND BIOLOGY, 46(10), 2625–2635.
author keywords: Ultrasound; Microbubbles; Contrast agent; Angiography; Angiogenesis; Microvasculature
MeSH headings : Acoustics; Angiography / methods; Angiography / trends; Animals; Contrast Media; Forecasting; Humans; Microvessels / diagnostic imaging; Neoplasms / blood supply; Neoplasms / diagnostic imaging; Neovascularization, Pathologic / diagnostic imaging; Ultrasonography
TL;DR:
This review describes the development of acoustic angiography, including the principle, transducer design, and optimization of superharmonic imaging techniques, and details several preclinical applications of this microvascular imaging method.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: September 28, 2020
2020 journal article
Structure of an anti-PEG antibody reveals an open ring that captures highly flexible PEG polymers
COMMUNICATIONS CHEMISTRY, 3(1).
TL;DR:
Crystal structures of an anti-PEG antibody binding fragment bound to PEG are reported and key binding residues are identified by site-directed mutagenesis to illustrate a strategy by which antibodies can bind highly flexible repeated structures that lack fixed conformations, such as polymers.
(via Semantic Scholar)
www.nature.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: September 28, 2020
2020 journal article
Deletion ofJNKEnhances Senescence in Joint Tissues and Increases the Severity of Age-Related Osteoarthritis in Mice
ARTHRITIS & RHEUMATOLOGY, 72(10), 1679–1688.
MeSH headings : Aging / metabolism; Animals; Cartilage, Articular / metabolism; Cellular Senescence / genetics; Chondrocytes / metabolism; Disease Models, Animal; Knee Joint / metabolism; Matrix Metalloproteinase 13 / metabolism; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 8 / genetics; Mitogen-Activated Protein Kinase 8 / metabolism; Mitogen-Activated Protein Kinase 9 / genetics; Mitogen-Activated Protein Kinase 9 / metabolism; Osteoarthritis / diagnosis; Osteoarthritis / genetics; Osteoarthritis / metabolism; Severity of Illness Index
TL;DR:
To determine the role of JNK signaling in the development of osteoarthritis (OA) induced by joint injury or aging in mice, a large number of mice were sacrificed and the JNK gene was switched off.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: September 14, 2020
2020 journal article
Direct Acoustic Imaging Using a Piezoelectric Organic Light-Emitting Diode
ACS APPLIED MATERIALS & INTERFACES, 12(32), 36409–36416.
author keywords: ultrasonic sensor; piezoelectric; organic light emitting diode; acousto optic conversion; ultrasound tomography
TL;DR:
A novel ultrasonic imaging device that can optically display an acoustic signal on the surface of a piezoelectric transducer that is operated without a need for conventional signal processing is reported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
7. Affordable and Clean Energy
(OpenAlex)
Source: Web Of Science
Added: September 14, 2020
2020 journal article
Photoinduced reconfiguration to control the protein-binding affinity of azobenzene-cyclized peptides
JOURNAL OF MATERIALS CHEMISTRY B, 8(33), 7413–7427.
MeSH headings : Amino Acid Sequence; Azo Compounds / chemistry; Hydrogen-Ion Concentration; Isomerism; Osmolar Concentration; Peptides, Cyclic / chemistry; Photochemical Processes
TL;DR:
This study demonstrates a general method to develop azobenzene-cyclized peptide ligands with light-controlled affinity for target proteins by designing photo-switchable peptides targeting vascular cell adhesion marker 1 (VCAM1), a cell marker implicated in stem cell function.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(Web of Science)
Source: Web Of Science
Added: September 14, 2020
2020 journal article
Effect of partial vs complete circumferential epitendinous suture placement on the biomechanical properties and gap formation of canine cadaveric tendons
VETERINARY SURGERY, 49(8), 1571–1579.
MeSH headings : Animals; Biomechanical Phenomena; Cadaver; Dogs / injuries; Dogs / surgery; Plastic Surgery Procedures / veterinary; Suture Techniques / veterinary; Sutures / veterinary; Tendon Injuries / surgery; Tendon Injuries / veterinary; Tendons / surgery; Tensile Strength
TL;DR:
Addition of a complete circumferential ES with a single or double knotting technique increased the biomechanical strength of normal tendon repairs while reducing gap formation compared with partial ES placement alone.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: September 7, 2020
2020 review
Microphysiological systems for the modeling of wound healing and evaluation of pro-healing therapies
[Review of ]. JOURNAL OF MATERIALS CHEMISTRY B, 8(32), 7062–7075.
MeSH headings : Animals; Cell Culture Techniques; Cell Line; Cell Movement; Cellular Microenvironment; Hemostasis / drug effects; Humans; Hydrogels / chemistry; Hydrogels / metabolism; Macrophages / metabolism; Microfluidics; Models, Animal; Skin; Stereolithography; Wound Healing / drug effects
TL;DR:
This review provides a brief overview of the wound healing process and in vivo assays, and critically review the current state of microphysiological systems and supporting technologies for modelling and studying wound healing.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: September 7, 2020
2020 journal article
Effect of the Organic Functionality on the Synthesis and Antimicrobial Activity of Silver Nanoparticles
NANO LIFE, 10(3).
author keywords: 3-aminopropyltrimethoxysilane; 3-glycidoxypropyltrimethylsilane; antimicrobial agents; silver nanoparticles; minimum inhibitory concentration; minimum bactericidal concentration; dose-dependent kill kinetics
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 31, 2020
2020 journal article
Assessing changes in attitudes toward engineering and biomechanics resulting from a high school outreach event
Journal of Biomechanics, 103, 109683.
author keywords: Outreach; High school; Engagement; Quantitative; Engineering; National Biomechanics Day
MeSH headings : Attitude; Biomechanical Phenomena; Engineering; Humans; Schools; Surveys and Questionnaires
TL;DR:
This quantitative study examines participants' attitude changes following one such event and finds significant gains in all three areas, which could lead to more students recruited to study a variety of engineering disciplines, ultimately addressing the ongoing national shortage of qualified engineers.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Sources: ORCID, Crossref, NC State University Libraries
Added: August 27, 2020
2020 journal article
Platelet-like particles improve fibrin network properties in a hemophilic model of provisional matrix structural defects
JOURNAL OF COLLOID AND INTERFACE SCIENCE, 577, 406–418.
author keywords: Fibrin; Biomimetic; Platelet; Hemophilia; Biomaterials
MeSH headings : Blood Coagulation; Blood Platelets; Fibrin; Plasma; Wound Healing
TL;DR:
PLPs improved clot network density, force generation, and stiffness, and promoted fibroblast migration within an in vitro model of early wound healing under hemophilic conditions, indicating that PLPs could provide a biomimetic platform for improving wound healing events in disease conditions that cause deficient fibrin network formation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 24, 2020
2020 journal article
Application of a Glucose Dehydrogenase-Fused with Zinc Finger Protein to Label DNA Aptamers for the Electrochemical Detection of VEGF
SENSORS, 20(14).
author keywords: aptamer; labeling; enzyme; zinc finger protein; glucose dehydrogenase; electrochemical sensor; vascular endothelial growth factor
MeSH headings : Aptamers, Nucleotide; Biosensing Techniques; Electrochemical Techniques; Glucose 1-Dehydrogenase; Humans; Vascular Endothelial Growth Factor A / analysis; Zinc Fingers
TL;DR:
This study used GDH that was genetically fused to a DNA binding protein, i.e., zinc finger protein (ZF), to demonstrate the concept of using ZF-fused GDH to enzymatically label aptamers for electrochemical detection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 24, 2020
2020 journal article
Older Adults Overcome Reduced Triceps Surae Structural Stiffness to Preserve Ankle Joint Quasi-Stiffness During Walking
JOURNAL OF APPLIED BIOMECHANICS, 36(4), 209–216.
author keywords: Achilles tendon; activation; aging; plantar flexor; biofeedback
TL;DR:
Despite age-related reductions during isolated contractions, ankle joint quasi-stiffness was maintained in older adults during walking, which may be governed via activation-mediated increases in muscle stiffness.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 17, 2020
2020 journal article
The Photoinitiator Lithium Phenyl (2,4,6-Trimethylbenzoyl) Phosphinate with Exposure to 405 nm Light Is Cytotoxic to Mammalian Cells but Not Mutagenic in Bacterial Reverse Mutation Assays
POLYMERS, 12(7).
author keywords: lithium phenyl (2; 4; 6-trimethylbenzoyl) phosphinate; gelatin methacryloyl; bioprinting; photoinitiator; light exposure; mutagenicity; cytotoxicity; photorheology
TL;DR:
The data indicate that the combination of LAP and free radicals generated from photo-excited LAP is cytotoxic, but mutagenicity was not observed in bacteria under typical bioprinting conditions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 17, 2020
2020 journal article
Argon and oxygen plasma treatment increases hydrophilicity and reduces adhesion of silicon-incorporated diamond-like coatings
BIOINTERPHASES, 15(4).
MeSH headings : Animals; Argon / chemistry; Cell Adhesion / drug effects; Cell Line; Cell Survival / drug effects; Coated Materials, Biocompatible / chemical synthesis; Coated Materials, Biocompatible / chemistry; Coated Materials, Biocompatible / pharmacology; Diamond / chemistry; Hydrophobic and Hydrophilic Interactions; Mice; Microscopy, Atomic Force; Oxygen / chemistry; Photoelectron Spectroscopy; Plasma Gases / chemistry; Silicon / chemistry; Surface Properties
TL;DR:
The suitability of Si-DLC coatings as inert coatings for medical and biotechnology applications is indicated by the results of the study.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 17, 2020
2020 journal article
High-Throughput Manufacture of 3D Fiber Scaffolds for Regenerative Medicine
TISSUE ENGINEERING PART C-METHODS, 26(7), 364–374.
author keywords: 3D printing; melt blowing; fibers; scaffolds
MeSH headings : Animals; Biocompatible Materials / chemistry; Dogs; Hernia / therapy; Herniorrhaphy / methods; Polymers / chemistry; Printing, Three-Dimensional / instrumentation; Regenerative Medicine; Tissue Engineering / methods; Tissue Scaffolds / chemistry
TL;DR:
The 3DMB system described in this study is modified from larger nonwovens manufacturing machinery to accommodate the lower volume, high-cost polymers used for tissue engineering and implantable biomedical devices and has a fiber collection component that uses adaptable robotics to create scaffolds with predetermined geometries.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 10, 2020
2020 journal article
Dermal exosomes containing miR-218-5p promote hair regeneration by regulating beta-catenin signaling
SCIENCE ADVANCES, 6(30).
MeSH headings : Cells, Cultured; Exosomes; Hair; Hair Follicle; MicroRNAs / genetics; Regeneration; beta Catenin / genetics
TL;DR:
Results revealed that DP spheroids are effective at inducing the progression of the hair follicle cycle from telogen to anagen compared with just DP cell or minoxidil treatment, and it was demonstrated that miR-218-5p was notably up-regulated in DP spheroid–derived exosomes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 10, 2020
2020 journal article
Assay and Isolation of Single Proliferating CD4+Lymphocytes Using an Automated Microraft Array Platform
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 67(8), 2166–2175.
author keywords: Immune system; Media; Optical filters; Magnetic resonance imaging; Microscopy; Sorting; Cancer; Microarrays; lymphocyte; proliferation; cell sorting; immunology
MeSH headings : CD4-Positive T-Lymphocytes; Cell Separation; Cells, Cultured; Humans; Lymphocyte Activation
TL;DR:
A versatile platform for single cell analysis and isolation that can be applied in immunology research and clinical therapy development is developed, capable of both identification and isolation of proliferative T cells in an automated manner.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 10, 2020
2020 journal article
Algorithmically Controlled Electroporation: A Technique for Closed Loop Temperature Regulated Pulsed Electric Field Cancer Ablation
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 67(8), 2176–2186.
author keywords: Temperature control; Temperature measurement; Temperature sensors; Electric fields; Protocols; Temperature dependence; In vitro; Non-thermal high frequency irreversible electroporation; electro-thermal therapy; pulsed electric field; bioelectric; electroporation
MeSH headings : Electricity; Electroporation; Humans; Models, Theoretical; Neoplasms; Temperature
TL;DR:
The results of this study indicate ablative outcomes due to exposure to pulses on the order of one microsecond may be thermally mediated and dependent on local tissue temperatures.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 10, 2020
2020 journal article
Spatial heterogeneity of the cytosol revealed by machine learning-based 3D particle tracking
MOLECULAR BIOLOGY OF THE CELL, 31(14), 1498–1511.
MeSH headings : Cytoplasm / metabolism; Cytoplasm / physiology; Cytosol / metabolism; Cytosol / physiology; Eremothecium / metabolism; Image Processing, Computer-Assisted / methods; Machine Learning; Nanoparticles; Orientation, Spatial / physiology; Single Molecule Imaging / methods
TL;DR:
The physical properties of the cytosol vary substantially in time and space and can be a source of heterogeneity within individual cells and across populations.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 3, 2020
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